The results of the risk factors study for the development of cerebrovascular diseases in women in Kyiv city

2020 ◽  
pp. 54-57
Author(s):  
G.О. Slabkiy ◽  
◽  
М.М. Prokopiv ◽  
Keyword(s):  
Risk Factors ◽  
Cerebrovascular Disease ◽  
Healthy Lifestyle ◽  
Cerebrovascular Diseases ◽  
Cerebral Stroke ◽  
Hypertensive Disease ◽  
Working Age ◽  
Hereditary Nature ◽  
High Level ◽  
The Impact

Cerebrovascular diseases in the leading countries of the world occupy the second place among all the causes of death and become the main cause of disability of the population in working age. Preventive measures for the development of cerebrovascular disease are directed at eliminating or reducing the impact of risk factors of disease. The objective: to define risk factors for the development of cerebrovascular disease in women under the age of 40 years residing in Kyiv. Materials and methods. 420 women under the age of 40 years residing in Kyiv were questioned with the use of sociological method. A universal adapted questionnaire was used to conduct the research. The results were processed with the application of statistical method and the method of structural-and-logical analysis. Results. It has been defined that up to 32.0% of women have risk factors for developing cerebrovascular diseases of medical nature, up to 69.0% – of hereditary nature, up to 69.0% – of those associated with lifestyle and 32.0% – of socio-economic nature. Among women who did not have a diagnosis of cerebrovascular disease 24.6±2.2% of the polled have hypertensive disease. At the same time, 21.9±2.1% of them do not follow the doctor’s recommendations on healthy lifestyle and 13.8±1.7% of them do not follow the recommendations of the doctor on taking medications. Among women who have been diagnosed with cerebrovascular disease 31.7±2.3% of the polled have hypertensive disease. At the same time, 48.7±2.5% of them do not follow the doctor’s recommendations on healthy lifestyle and 38.5±2.4% do not follow the recommendations of the doctor regarding the intake of medicines. All that leads to high risks of developing a cerebral stroke. Conclusions. A high level of risk factors for cerebrovascular disease was defined among women aged up to 40 years of life residing in Kyiv that requires the introduction of comprehensive information and sanitary preventive programs. Keywords: Kyiv, women, cerebrovascular diseases, risk factors.

IDENTIFICATION AND ASSESSMENT OF RISK FACTORS ROLE IN MYOCARDIAL INFARCTION DEVELOPMENT

2019 ◽  
Vol 72 (5) ◽  
pp. 779-783
Author(s):  
Victor A. Ognev ◽  
Anna A. Podpriadova ◽  
Anna V. Lisova
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Cardiovascular System ◽  
Control Group ◽  
Biological Factors ◽  
Prevention And Treatment ◽  
High Level ◽  
Social Importance ◽  
The Impact

Introduction:The high level of morbidity and mortality from cardiovascular disease is largely due toinsufficient influence on the main risk factors that contribute to the development of myocardial infarction.Therefore, a detailed study and assessment of risk factors is among the most important problems of medical and social importance. The aim: To study and evaluate the impact of biological, social and hygienic, social and economic, psychological, natural and climatic risk factors on the development of myocardial infarction. Materials and methods: A sociological survey was conducted in 500 people aged 34 to 85. They were divided into two groups. The main group consisted of 310 patients with myocardial infarction. The control group consisted of 190 practically healthy people, identical by age, gender and other parameters, without diseases of the cardiovascular system. Results: It was defined that 30 factors have a significant impact on the development of myocardial infarction.Data analysis revealed that the leading risk factors for myocardial infarction were biological and socio-hygienic. The main biological factors were: hypertension and hypercholesterolemia. The man socio-hygienic factor was smoking. Conclusions: Identification of risk factors provides new opportunities for the development of more effective approaches for the prevention and treatment of myocardial infarction.

scholarly journals Methionine Diet Evoked Hyperhomocysteinemia Causes Hippocampal Alterations, Metabolomics Plasma Changes and Behavioral Pattern in Wild Type Rats

2021 ◽  
Vol 22 (9) ◽  
pp. 4961
Author(s):  
Maria Kovalska ◽  
Eva Baranovicova ◽  
Dagmar Kalenska ◽  
Anna Tomascova ◽  
Marian Adamkov ◽  
...  
Keyword(s):  
Morphological Changes ◽  
Brain Area ◽  
Critical Role ◽  
Cerebrovascular Diseases ◽  
Behavioral Pattern ◽  
Cell Physiology ◽  
Male Wistar Rats ◽  
High Level ◽  
Hippocampal Alterations ◽  
The Impact

L-methionine, an essential amino acid, plays a critical role in cell physiology. High intake and/or dysregulation in methionine (Met) metabolism results in accumulation of its intermediate(s) or breakdown products in plasma, including homocysteine (Hcy). High level of Hcy in plasma, hyperhomocysteinemia (hHcy), is considered to be an independent risk factor for cerebrovascular diseases, stroke and dementias. To evoke a mild hHcy in adult male Wistar rats we used an enriched Met diet at a dose of 2 g/kg of animal weight/day in duration of 4 weeks. The study contributes to the exploration of the impact of Met enriched diet inducing mild hHcy on nervous tissue by detecting the histo-morphological, metabolomic and behavioural alterations. We found an altered plasma metabolomic profile, modified spatial and learning memory acquisition as well as remarkable histo-morphological changes such as a decrease in neurons’ vitality, alterations in the morphology of neurons in the selective vulnerable hippocampal CA 1 area of animals treated with Met enriched diet. Results of these approaches suggest that the mild hHcy alters plasma metabolome and behavioural and histo-morphological patterns in rats, likely due to the potential Met induced changes in “methylation index” of hippocampal brain area, which eventually aggravates the noxious effect of high methionine intake.

scholarly journals Identification and Qualitative Evaluation of Risk Factors in the Construction Projects in Iraq

2021 ◽  
Vol 14 (2) ◽  
pp. 91-101
Author(s):  
Noor Aletby ◽  
Hafeth Ibrahim
Keyword(s):  
Risk Factors ◽  
Risk Management ◽  
Construction Projects ◽  
Qualitative Evaluation ◽  
Qualitative Assessment ◽  
Management Process ◽  
Risk Management Process ◽  
Questionnaire Method ◽  
High Level ◽  
The Impact

Construction projects in Iraq face many dangers that cause exceeding the estimated cost of the project and not completing the project on time, and since the risk management process in construction projects is of great importance in controlling and reducing the impact of risks in construction projects, so it is necessary to identify these risks and evaluate them correctly in order to increase accuracy and the health of the subsequent stages of the risk management process in construction projects. This paper aims to identify the most important risks in construction projects in Iraq and to conduct a qualitative assessment of the identified risks and arrange them according to their importance. The researcher adopted the questionnaire method as a tool to determine the risks and used the technique of probability and effect matrix to conduct the qualitative assessment of the identified risks. The study found that there are 48 risk factors that constitute the most dangerous factor in construction projects in Iraq, and 10 of the determining factors were within the high level of risk, and at the forefront of which was the inability of the owner to finance the project.

scholarly journals Modifiable Lifestyle Factors: Opportunities for (Hereditary) Breast Cancer Prevention - a Narrative Review

Breast Care ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. 108-113 ◽  
Author(s):  
Jacqueline Lammert ◽  
Sabine Grill ◽  
Marion Kiechle
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cancer Prevention ◽  
Healthy Lifestyle ◽  
Absolute Risk ◽  
Lifestyle Factors ◽  
Breast Cancer Prevention ◽  
The Impact

Increasing rates of obesity, lack of physical activity, sedentary behavior, and frequent alcohol consumption are major lifestyle-related risk factors for breast cancer. In fact, it has been estimated that about one-third of breast cancer cases are attributable to factors women can change. Most research has focused on examining the impact of one single exposure on breast cancer risk while adjusting for other risk modifiers. Capitalizing on big data, major efforts have been made to evaluate the combined impact of well-established lifestyle factors on overall breast cancer risk. At the individual level, data indicate that even simple behavior modifications could have a considerable impact on breast cancer prevention. Moreover, there is emerging new evidence that adopting a healthy lifestyle may be particularly relevant for women with hereditary susceptibility to breast cancer. On the absolute risk scale, studies suggest that the presence of certain risk factors, such as excessive body weight, had a substantially higher impact on breast cancer risk if women had a hereditary predisposition to cancer. The existing body of knowledge gives the medical professionals guidance as to which factors to focus on when counseling patients. However, well-designed randomized controlled trials utilizing objective methods are crucial to providing concrete recommendations.

scholarly journals Arterial hypertension in young men, officers of land forces: psychophysiological peculiarities

2013 ◽  
Vol 4 (2) ◽  
pp. 11-15
Author(s):  
I. M Davidovich ◽  
O. V Afonaskov
Keyword(s):  
Risk Factors ◽  
Arterial Hypertension ◽  
Heart Rhythm ◽  
Hypertensive Disease ◽  
Heart Rhythm Variability ◽  
Additional Risk ◽  
Cognitive Loading ◽  
Arterial Blood ◽  
Personal Anxiety ◽  
High Level

The authors have studied heart rhythm variability at rest and with cognitive loading, types of coronary behavior and reactive and personal anxiety in 86 men of young age, officers of the land forces. 52 of them had hypertensive disease (HD) of I–II stage. 34 men had normal arterial blood pressure. Patients with HD in comparison with normotensive men turned out to have additional risk factors accompanied arterial hypertension. They were hypersympaticotonia, high level of personal anxiety and coronary behavior type A.

scholarly journals Diabetes in the Context of Stroke (Local Study)

2021 ◽  
pp. 1-5
Author(s):  
Magda Mostafa ◽  
Mohamad Aladlany ◽  
Mohamad Sherif ◽  
Mohammed Abbas
Keyword(s):  
Cardiovascular Complications ◽  
Cerebrovascular Diseases ◽  
Cerebral Stroke ◽  
Diabetic Patients ◽  
Stroke Severity ◽  
Base Line ◽  
Local Study ◽  
Established Risk Factor ◽  
Group B ◽  
The Impact

Background: Cerebrovascular diseases (CVD), including stroke, are considered as a high burden heath issue around the world. Diabetes is a well-established risk factor for stroke that affects both severity and outcome. Objectives: The objective of this study is to evaluate cerebral stroke in diabetic patients and the impact of diabetes mellitus on the severity and outcome of all types of strokes. Patients and Methods: This study included 500 patients with the first attack stroke who were classified into two groups; Group A: 404 diabetic patients & Group B: 96 non-diabetic patients. All patients were diagnosed clinically and with base line CT (Computed Tomography) brain and stroke severity was evaluated by NIHSS within 24 hours of admission. Results: The mean NIHSS in the diabetic cases was 10.35 ± 2.51 which was statistically significant higher as compared with the non-diabetic cases (7.25 ± 1.02) (P <0.001). The percentage of cases with infarction stroke was higher in the diabetic group, however it did not detect major dissimilarity between the 2 groups. Conclusion: Cardiovascular complications including cerebral strokes occur in higher rates in diabetic patients as compared with the non-diabetic. The outcomes of cerebral strokes were worse as compared with the non-diabetic.

scholarly journals Possibilities of telemedical monitoring risk factors in patients with cardiovascular diseases: experience of using a patient-oriented model of remote rehabilitation care

2021 ◽  
Vol 65 (6) ◽  
pp. 549-556
Author(s):  
Elena V. Kotelnikova ◽  
Valery N. Senchikhin ◽  
Tatyana P. Lipchanskaya
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
Cardiac Rehabilitation ◽  
Healthy Lifestyle ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Rehabilitation Care ◽  
Rehabilitation Model ◽  
High Level ◽  
Remote Assistance

Introduction. The modern system for the prevention of cardiovascular diseases and the creation of conditions for the formation and maintenance of a healthy lifestyle (coolant) includes activities in the development of monitoring systems for information on risk factors. Purpose: to assess the capabilities of telemedicine monitoring of cardiovascular risk factors in the structure of a patient-oriented model of distance rehabilitation care. Material and methods. The study included patients with coronary heart disease and/or arterial hypertension of the I-III degree, without cognitive dysfunction and contraindications to physical rehabilitation, with a mobile device with Internet access. The following groups were distinguished: remote cardiac rehabilitation, with the participation of patients in a 12-month program (28 patients, 86% of men, average age 55.2 ± 10.7 years), and traditional follow-up (30 patients, 80% of men, average age 64.7 ± 6.9 years). Remote cardiac rehabilitation model provided for office consulting using a decision support system, monitoring indicators based on digital recording devices, mobile applications and the electronic «Patient Diary» deferred telemedicine counselling. The effectiveness of the observation was evaluated by the trend of the modified risk factors; patient satisfaction with remote assistance - according to the «Client Satisfaction Questionnaire - CSQ-8» questionnaire. Results. After completion of the remote cardiac rehabilitation (RCR) program, a significant decrease in systolic and diastolic blood pressure, total cholesterol, low-density lipoprotein cholesterol and triglycerides were observed, and a tendency to increase physical activity. Upon completion of the RCR-program, a high level of satisfaction with telemedicine assistance was noted. Conclusion. The results of the pilot phase of the study, dedicated to the study of the possibilities of remote rehabilitation in the context of maximizing the benefits for cardiovascular prophylaxis, indicate the possibility of using a patient-oriented model of remote cardiac rehabilitation to monitor and modify risk factors in patients with cardiovascular diseases.

scholarly journals The Impact of Lifestyle Interventions in High-Risk Early Breast Cancer Patients: A Modeling Approach from a Single Institution Experience

Cancers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 5539
Author(s):  
Mirco Pistelli ◽  
Valentina Natalucci ◽  
Laura Scortichini ◽  
Veronica Agostinelli ◽  
Edoardo Lenci ◽  
...  
Keyword(s):  
Risk Factors ◽  
Nutrition Education ◽  
Healthy Lifestyle ◽  
Serum Insulin ◽  
Depression Scale ◽  
Well Being ◽  
Lifestyle Interventions ◽  
Testosterone Levels ◽  
Significant Difference ◽  
The Impact

A healthy lifestyle plays a strategic role in the prevention of BC. The aim of our prospective study is to evaluate the effects of a lifestyle interventions program based on special exercise and nutrition education on weight, psycho-physical well-being, blood lipid and hormonal profile among BC patients who underwent primary surgery. From January 2014 to March 2017, a multidisciplinary group of oncologists, dieticians, physiatrists and an exercise specialist evaluated 98 adult BC female patients at baseline and at different time points. The patients had at least one of the following risk factors: BMI ≥ 25 kg/m2, high testosterone levels, high serum insulin levels or diagnosis of MS. Statistically significant differences are shown in terms of BMI variation with the lifestyle interventions program, as well as in waist circumference and blood glucose, insulin and testosterone levels. Moreover, a statistically significant difference was reported in variations of total Hospital Anxiety and Depression Scale (HADS) score, in the anxiety HADS score and improvement in joint pain. Our results suggested that promoting a healthy lifestyle in clinical practice reduces risk factors involved in BC recurrence and ensures psycho-physical well-being.

scholarly journals HIV Associated Risk Factors for Ischemic Stroke and Future Perspectives

2020 ◽  
Vol 21 (15) ◽  
pp. 5306
Author(s):  
Saifudeen Ismael ◽  
Mohammad Moshahid Khan ◽  
Prashant Kumar ◽  
Sunitha Kodidela ◽  
Golnoush Mirzahosseini ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Hiv Infection ◽  
Opportunistic Infections ◽  
Experimental Studies ◽  
Chronic Administration ◽  
Cerebrovascular Diseases ◽  
Vascular Abnormalities ◽  
Increased Risk ◽  
The Impact

Although retroviral therapy (ART) has changed the HIV infection from a fatal event to a chronic disease, treated HIV patients demonstrate high prevalence of HIV associated comorbidities including cardio/cerebrovascular diseases. The incidence of stroke in HIV infected subjects is three times higher than that of uninfected controls. Several clinical and postmortem studies have documented the higher incidence of ischemic stroke in HIV infected patients. The etiology of stroke in HIV infected patients remains unknown; however, several factors such as coagulopathies, opportunistic infections, vascular abnormalities, atherosclerosis and diabetes can contribute to the pathogenesis of stroke. In addition, chronic administration of ART contributes to the increased risk of stroke in HIV infected patients. Concurrently, experimental studies in murine model of ischemic stroke demonstrated that HIV infection worsens stroke outcome, increases blood brain barrier permeability and increases neuroinflammation. Additionally, residual HIV viral proteins, such as Trans-Activator of Transcription, glycoprotein 120 and Negative regulatory factor, contribute to the pathogenesis. This review presents comprehensive information detailing the risk factors contributing to ischemic stroke in HIV infected patients. It also outlines experimental evidence demonstrating the impact of HIV infection on stroke outcomes, in addition to possible novel therapeutic approaches to improve these outcomes.

Risks of health disorders in pedagogical, medical workers and preventive measures

2021 ◽  
Vol 61 (12) ◽  
pp. 833-840
Author(s):  
Evgeniy A. Bayimakov ◽  
Irena A. Mishkich ◽  
Olga I. Yushkova ◽  
Anna V. Zajtseva ◽  
Khristina T. Oniani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Motor Activity ◽  
Emotional Labor ◽  
Healthy Lifestyle ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
Production Studies ◽  
Health Disorders ◽  
General Physical ◽  
High Level

The formation of a healthy lifestyle and a healthy lifestyle in the work of various activities, developing a program that includes appropriate measures to correct the functional state of employees of nervous and emotional labor, is currently one of the essential areas of occupational health. The study aims to assess the prevalence of behavioral risk factors for health disorders and the effectiveness of measures to correct overstrain in pedagogical and medical workers, depending on the personal level of anxiety. The researchers conducted comprehensive physiological and hygienic studies. We described behavioral risk factors, awareness of health-saving issues based on a questionnaire (346 teachers), a professional graphical assessment of the intensity of efforts. Psychophysical studies help to study the states of various functions of the central nervous system and the cardiovascular system, psychological testing, and general physical performance (GPP) according to the RWC170 test when evaluating the implemented model of motor activity and assess the effectiveness of relaxation in the shungite room. We performed static processing of the data obtained using statistical programs EpiInfo 3.5.2., Statistica 10, Microsoft Excel 2010 using adequate methods of statistical analysis. The study of the prevalence of the factors risky cheek of life for the health of teachers revealed insufficient physical activity (61.1% (95% CI 54.7-67.2)), inadequate sleep duration (46.1% (95% CI 40.0-52.4)), eating disorders (16.2% (95% CI 11.9-21.5)) tobacco smoking (15.8% (95% CI 11.5-20.9)). The developed and implemented regime, which increases the volume of motor activity to 8-9 hours a week instead of 3-4 hours, contributed to an increase in resistance to stress effects, a decrease in the percentage of identified teachers with a low level of physical fitness. A high degree of nervous and emotional tension in the work of general practitioners, the possibility of infection with COVID-19 leads to the formation of a high level of anxiety in a significant part (63.7-72.2%) of medical workers, which indicates the purposefulness of a psychological correction measure. The conducted production studies have shown the usefulness of using in programs for correcting the functional conformity of pedagogical and medical workers, an increase in motor activity using physical culture and sports, and relaxation in the shungite room.

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