scholarly journals Anxiety, Depression and Sleep Disturbances among Renal Disorders in Tertiary Care Center

2021 ◽  
Vol 12 (1) ◽  
pp. 310-314
Author(s):  
Saritha CH. V. N. ◽  
Gowtham Reddy C.

Depression is the most general psychiatric disease in patients with Chronic Kidney Disease (CKD). Depression exposed to affect mortality in end-stage renal disease patient. The main focus of this study was to measure the occurrence of painful symptoms among CKD patients. Co-morbid depression influences harmfully on the excellence of life in Chronic Kidney Disease patients. This study was done to calculate predominance of depression inpatient on hemodialysis (HD) using Patient Health Questionnaire-9, Hamilton Rating Scale for Depression-17 and International Classification of Disease-10 classification of mental and behavioural disorders. It was a cross-sectional study conducted from December 2019 till July 2020, in Nandhyala, Kurnool district region. Informed and written consent was taken. Patients undergoing hemodialysis at the Nandhyala, Kurnool district region for more than three months duration were involved in the study. Psychiatrists monitored Hamilton Rating scale for diagnosis and categorization of depression. Psychiatrists confirmed depression based on International Classification of Disease-10 scale. SPSS version.20 was used for statistical analysis. The study was done among 300 patients. Prevalence of depression was 234 using Patient Health Questionnaire-9 (PHQ-9)and 195 using Hamilton Rating scale (HAD-17)and 153 using International Classification of Disease -10 (ICD-10). Mean depression in females using PHQ-9 was 7±4.33 and in males was 11.04±5.90, and the Median age was 47.6 years. The most common symptom was fatigue among 246. There is a high occurrence of depression in patients with Chronic Kidney Disease (CKD) stage 5 on hemodialysis compared to the general population. 

2019 ◽  
Vol 57 (217) ◽  
Author(s):  
Krishna Kumar Agrawaal ◽  
Pramod Kumar Chhetri ◽  
Pradip Man Singh ◽  
Dhiraj Narayan Manandhar ◽  
Prakash Poudel ◽  
...  

Introduction: Co-morbid depression impacts negatively on quality of life in Chronic Kidney Diseasepatients. It is unclear if self-reported depression rating scales can be used accurately for screening.The aim of this study was to estimate prevalence of depression in patients on hemodialysis usingPatient Health Questionnaire-9 and compare Patient Health Questionnaire-9, Max Hamilton Ratingscale and International Classification of Disease-10 for diagnosis of depression. Methods: It was descriptive cross-sectional study conducted from November 2017 till June 2018.Ethical approval was taken from Ethical Review Board, Nepal Health Research Council. Informedand written consent was taken. Patients undergoing hemodialysis at Nepal Medical College for >3 months duration were included in study. Patients on hemodialysis were asked to fill validatedNepali translated version of Patient Health Questionnaire -9. Psychiatrist administered MaxHamilton Rating scale for diagnosis and categorization of depression and confirmed depressionbased on International Classification of Disease -10. Statistical Package for Social Sciences version 20was used for statistical analysis. Results: Total of 100 patients completed study. Median age was 47.5 years. Prevalence of depressionwas 78 (78%) using Patient Health Questionnaire-9 and 65 (65%) using Max Hamilton Rating scaleand 51 (51%) using International Classification of Disease -10. Mean depression in males using PatientHealth Questionnaire -9 was 7±4.33 and in females was 11.04±5.90. The most common symptom wasfatigue among 82 (82%). Conclusions: There is a high prevalence of depression in patients with Chronic Kidney Disease onhemodialysis compared to general population.


Author(s):  
Eldislei Mioto ◽  
Marco Utiumi ◽  
João Küster ◽  
Bin Tan ◽  
Nikolai Kotsifas ◽  
...  

IntroduçãoOs ataques de migrânea são caracterizados por sintomas álgicos e não álgicos. Além disso, a migrânea ocorre associada a diversas comorbidades. Tanto os sintomas não álgicos como as comorbidades podem se caracterizar por sintomas autonômicos. Este trabalho tem por objetivo avaliar a disautonomia em migranosos e diferenças relacionadas entre os grupos episódico (ME) e crônico (MC).Material e MétodosEstudo transversal de pacientes atendidos em ambulatório especializado, diagnosticados pela International Classification of Headache Disorders 3 como ME ou MC, convidados de forma consecutiva e utilizando entrevistas semi-estruturadas. O questionário Composite Autonomic Symptom Score (COMPASS) foi utilizado para avaliação de sintomas autonômicos, o Patient Health Questionnaire (PHQ) 9 para avaliação de sintomas depressivos e o Short Form (SF) 36 para avaliação de qualidade de vida. O estudo foi aprovado pelo comitê de ética do HC- UFPR.ResultadosForam incluídos 210 pacientes dos quais 97 (46%) apresentavam ME e 113 (54%) MC. Destes, 78 (69%) consumiam analgésicos excessivamente. A média de idade era de 39,5±12,6 anos e 189 (90%) pacientes eram do sexo feminino. O grupo CM apresentou um escore COMPASS mais alto (34,7±18,3) que o grupo EM (26,4±14,8). A regressão múltipla foi empregada para analisar a associação das variáveis clínicas com o COMPASS. O modelo final ajustado mostra que para cada sintoma não álgico tipicamente vistos na aura de tronco encefálico, há um incremento médio de 2,17-6,3 no COMPASS. Para cada ponto a mais no PHQ9, o COMPASS eleva-se entre 0,78-1,84 em média. Todos os processos de inferência consideraram um valor alpha de 0.05.ConclusãoO processo de cronificação pode cursar com mais sintomas disautonômicos. Estes, por sua vez, estão associados a mais sintomas atribuídos a alterações de tronco e à depressão, indicando esta área como potencialmente envolvida nesta gama de sintomas.


2021 ◽  
Vol 12 ◽  
Author(s):  
Simeng Ma ◽  
Jun Yang ◽  
Bingxiang Yang ◽  
Lijun Kang ◽  
Peilin Wang ◽  
...  

Background: The Hamilton Rating Scale for Depression (HAMD-17) has been used for several decades to assess the severity of depression. Multiple studies have documented defects in this scale and deemed it unsuitable for clinical evaluation. The HAMD-6, which is the abbreviated version of HAMD-17, has been shown to be effective in assessing the core symptoms of depression with greater sensitivity than HAMD-17. And the Patient Health Questionnaire-9 (PHQ-9) is suggested as an effective alternative to the HAMD-17 because of its simplicity and ease-of-use.Methods: Research was completed involving 1,741 participants having major depressive disorder. Cronbach's alpha, intraclass correlation coefficient (ICC) and weighted Kappa analysis was used to determine the reliability of the scales. Pearson correlation analysis and factor analysis were used to analyze validity. Item response theory (IRT) was used to analyze psychological characteristics of items in both the HAMD-17 and PHQ-9.Results: Reliability analysis showed that the Cronbach's alpha of the HAMD-17, HAMD-6 and PHQ-9 were 0.829, 0.764, and 0.893 respectively, and the ICC of the three scales ranged from 0.606 to 0.744. The Kappa score of the consistency of depression severity assessment was 0.248. Validity analysis showed that the PHQ-9 was a single factor structure, and the total score of the scale was strongly correlated with the HAMD-17 (r = 0.724, P < 0.001). The IRT analysis showed that the discrimination parameters of the PHQ-9 were higher than that of the HAMD-17 in all dimensions. The HAMD-6 had the lowest measurement accuracy in distinguishing the severity of depression, while the PHQ-9 had the highest measurement accuracy.Conclusion: Results showed that the PHQ-9 was satisfactory in terms of reliability, validity and distinguishing the severity of depression. It is a simple, rapid, effective and reliable tool which can be used as an alternative to the HAMD-17 to assess the severity of depression.


2009 ◽  
Vol 54 (2) ◽  
pp. 198-203 ◽  
Author(s):  
Ryan T. Williams ◽  
◽  
Allen W. Heinemann ◽  
Rita K. Bode ◽  
Catherine S. Wilson ◽  
...  

2020 ◽  
Vol 20 (2) ◽  
Author(s):  
Maryatun Hasan

Abstrak. Penyakit ginjal kronis (PGK) merupakan penyakit yang dapat mengakibatkan penderitanya mengalami stress jangka panjang dan akhirnya bermanifestasi menjadi depresi. Depresi yang ditimbulkan dapat mempengaruhi perilaku pasien dalam hal pengaturan cairan sehingga dapat berakibat terhadap peningkatan Interdialytic Weight Gain (IDWG). Jika IDWG meningkat maka akan menimbulkan komplikasi yang dapat menghambat keberhasilan terapi hemodialisis.  Penelitian ini bertujuan untuk mengetahui gambaran tingkat depresi terhadap terjadinya peningkatan Interdialytic Weight Gain pada pasien PGK yang menjalani hemodialisis di RSUDZA Banda Aceh. Jenis penelitian ini adalah deskriptif analitik dengan pendekatan cross sectional. Pengumpulan data dilakukan pada bulan Desember 2019 menggunakan teknik accidental sampling dengan responden adalah pasien di unit hemodialisis RSUDZA Banda Aceh. Pengumpulan data dilakukan dengan menggunakan kuesioner Hamilton Rating Scale for Depression kemudian dilakukan analisis univariat untuk mengatahui gambaran dari penelitian dan bivariat dengan menggunakan uji korelasi Spearman. Berdasarkan hasil analisis statistik dengan menggunakan uji Spearman, didapatkan p value sebesar 0,000 (p0,05) dengan koefisien korelasi Spearman sebesar 0,729. Hal ini menunjukkan adanya hubungan yang signifikan antara tingkat depresi dengan peningkatan IDWG pada pasien PGK yang menjalani hemodialisis di RSUDZA Banda Aceh.Kata Kunci: Penyakit Ginjal Kronis, Hemodialisis, Depresi, Interdialytic Weight GainAbstract. Chronic kidney diasease (CKD) might cause stress which generally leads to depression. Depression is correlated to significant impairment in a patient's daily life, such as excessive Interdialytic Weight Gain (IDWG) caused by an overload of fluids. Excessive Interdialytic Weight Gain might also cause other complications that are able to interfere the process of hemodialysis therapy. The objective of this research was to identify the overview of and the correlation between depression types and Interdialytic Weight Gain (IDWG) of the chronic kidney disease patients undergoing hemodialysis therapy in dr. Zainoel Abidin Regional Public Hospital of Banda Aceh. This descriptive analytical research was conducted by means of a cross-sectional study approach. The data were collected in December 2019 by using an accidental sampling technique. The data were collected by distributing the Hamilton Rating Scale for Depression. Those data were then analyzed by using a univariate data analysis and a bivariate data analysis, especially the Spearman Correlation Coefficient. Based on the statistical analysis with the Spearman test, p-value of 0.000 (p0.05) with a Spearmen Correlation Coefficient of 0.729 was found. Hence, a significant correlation between depression levels or types and IDWG in chronic kidney disease patients undergoing hemodialysis in dr. Zainoel Abidin Regional Public Hospital of Banda Aceh was indicated.Keywords: Chronic Kidney Disease, hemodialysis, Depression, Interdialytic Weight Gain


2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Fitri Amalia ◽  
Nadjmir Nadjmir ◽  
Syaiful Azmi Azmi

AbstrakDepresi merupakan salah satu dari gangguan mood yang utama. Tanda dan gejala lain gangguan mood adalah perubahan tingkat aktivitas, kemampuan kognitif, pembicaraan dan fungsi vegetatif seperti tidur, nafsu makan, aktivitas seksual dan irama biologis lainnya. Perubahan tersebut hampir selalu menyebabkan gangguan fungsi interpersonal, social, dan pekerjaan. Tujuan penelitian ini adalah untuk mengetahui gambaran tingkat depresi pada pasien penyakit ginjal kronik yang menjalani hemodialisis di RSUP Dr. M. Djamil. Penelitian ini merupakan penelitian deskriptif dengan desain cross sectional study. Subjek diambil dari seluruh populasi yang memenuhi kriteria inklusi menggunakan teknik total sampling, Subjek yang memenuhi kriteria inklusi diwawancarai menggunakan The Hamilton Rating Scale For Depression dari seluruh populasi didapatkan 16 subjek yang memenuhi kriteria. Hasil yang didapatkan ialah 9 responden (56,25%) tidak mengalami depresi, depresi ringan 6 responden (37,50%) dan depresi sedang 1 responden (6,25%). Dapat disimpulkan tingkat depresi terbanyak pada pasien penyakit ginjal kronik yang menjalani hemodialisis di RSUP DR. M. Djamil tahun 2013 adalah tingkat depresi ringan. Karakteristik responden terbanyak yang mengalami depresi adalah sebagai berikut: umur 40-49 tahun, perempuan, menikah, berpendidikan terakhir SMA, pekerjaan ibu rumah tangga dan tidak bekerja.Kata kunci: depresi, penyakit ginjal kronik, hemodialisisAbstractDepression is one of the major of mood disorders. Other signs and symptoms of mood disorders are changes in the level of activity, cognitive ability, speech and vegetative functions such as sleep, appetite, sexual activity and other biological rhythms. Such changes always lead to malfunction of interpersonal, social and employment. The objective of this study was to describe the level of depression in patients with chronic kidney disease who undergoing hemodialysis at RSUP Dr. M. Djamil Padang. This was a descriptive study using a cross sectional design. Subject were taken from the entire population who met the inclusion criteria using total sampling technique, subject who met the inclusion criteria were interviewed using the Hamilton Rating Scale for Depression, of the entire population obtained 16 subjects that meet the criteria. From this study, a 9 respondents (56.25%) did not experience depression, 6 respondents (37.50%) mild depression and 1 respondent (6.25%) moderate depression. It can be concluded highest rates of depression in patients with chronic kidney disease undergoing hemodialysis at RSUP DR. M. Djamil Padang in 2013 in the level of mild depression. Most characteristics of the respondents who were depressed were as follows : age 40-49 years, female, married, educated, past high school, housewives work and do not work, 13-18 months undergoing hemodialysis.Keywords: depression, chronic kidney disease, hemodialysis


2020 ◽  
Vol 18 (5) ◽  
pp. 1116-1123
Author(s):  
José Cândido de Araújo Filho ◽  
Frederico Castelo Branco Cavalcanti ◽  
Gleydson Silva Morais ◽  
Shirley Dias Bezerra ◽  
Marthley José Correia Costa ◽  
...  

Nephron ◽  
2021 ◽  
pp. 1-12
Author(s):  
Alyshah Abdul Sultan ◽  
Glen James ◽  
Xia Wang ◽  
Seth Kuranz ◽  
Katarina Hedman ◽  
...  

<b><i>Introduction:</i></b> Further understanding of adverse clinical events in patients with chronic kidney disease (CKD) is needed. This study aimed to describe characteristics of patients with nondialysis-dependent (NDD) and dialysis-dependent (DD) CKD and to assess incidence rates of uncommon adverse clinical events of interest in these patients. <b><i>Methods:</i></b> This retrospective study used electronic medical record data from USA CKD patients (≥18 years) with estimated glomerular filtration rate (eGFR) &#x3c;60 mL/min/1.73 m<sup>2</sup> between January 1, 2010, and December 31, 2018, obtained from the USA-based TriNetX database. NDD-CKD and DD-CKD were diagnosed and staged from ≥2 consecutive eGFR readings, recorded ≥90 days apart. Dialysis was identified using procedure codes for renal replacement therapy. Outcomes assessed were select uncommon adverse clinical events, defined by International Classification of Disease, 9th and 10th Revision codes. <b><i>Results:</i></b> Incidence rates of adverse clinical events per 100 person-years (95% confidence interval) were generally higher in patients with DD-CKD versus NDD-CKD. Differences were particularly pronounced for hyperkalemia (26.9 [26.2–27.6] vs. 4.5 [4.5–4.6]), acidosis (15.1 [14.7–15.6] vs. 3.4 [3.4–3.4]), and sepsis (14.6 [14.2–15.1] vs. 3.3 [3.3–3.4]). Among DD-CKD patients, incidence rates of adverse events were particularly high during the first 3 months following dialysis initiation. Incidence of adverse clinical events generally increased with decreasing eGFR among patients with NDD-CKD and with hemoglobin &#x3c;10 g/dL in both NDD- and DD-CKD patients. <b><i>Conclusions:</i></b> Our results help establish baseline rates of uncommon adverse clinical events and provide additional evidence of increased morbidity for patients with DD-CKD versus NDD-CKD.


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