scholarly journals Analysis of the Effect of Anesthetics Comprising of Remifentanil Combined with Propofol During Thyroidectomy

2019 ◽  
Vol 3 (5) ◽  
Author(s):  
Qikai Liao

Objective: To analyze the anesthetic effect of remifentanil combined with propofol during thyroidectomy. Methods: A total of 70 patients who underwent thyroidectomy during November 2018 to November 2019 in Chongqing Eleventh People's Hospital were selected and recruited. These patients were divided into control group and observation group by random number table method. Each group consisted of 35 patients. The patients in the control group was given intravenous anesthesia comprising of propofol combined with intermittent fentanyl anesthesia, whereas the patients in the observation group was given intravenous anesthesia comprising of remifentanil combined with propofol. Results: The heart rate and mean arterial pressure of the observation group after anesthesia for 30 minutes were lower than those of the control group, and the differences were statistically significant (P < 0.05). The total incidence of adverse reactions in the observation group was lower than that of the control group, and the differences were statistically significant (P < 0.05). Conclusion: Remifentanil combined with propofol is effective in thyroidectomy. This combination can reduce the risk of adverse reactions and maintain stable hemodynamic parameters.

2021 ◽  
Vol 5 (4) ◽  
pp. 112-116
Author(s):  
Liang Wang ◽  
Li Liu ◽  
Zhenghui Liu

Objective: To observe the efficacy of Yin-tonifying Ophiopogonis Decoction combined with Rehabilitation New Liquid in the treatment of reflux esophagitis (RE). Methods: Seventy-four patients with RE were included in the study and they were divided into an observation group and a control group using the random number table method with 37 cases in each group. The patients in the control group were given oral Yin-tonifying Ophiopogonis Decoction whereas the patients in the observation group were additionally treated with the Rehabilitation New Liquid. The clinical efficacy, traditional Chinese medicine (TCM) symptoms, and the efficiency of gastroscopy were compared between the two groups. Results: The total effective rate of clinical symptoms, TCM symptoms, and gastroscopy results between the observation group and the control group were significantly different (P < 0.05) and were statistically significant. Conclusion: The clinical effect of Yin-tonifying Ophiopogonis Decoction combined with the Rehabilitation New Liquid in the treatment of RE is significant.


2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Liang Yanqm

<p>ObjectiveToinvestigate the clinical effect of indomethacin suppositories prevention of POST-ERCP acute. Pancreatitis20&gt;Methods180 cases of ERCP were selected from March to September 2015 in ourHospital, all the patients according to the random number table were divided into two groups, there were-cases in the OBsenTation Group and the control group.Hie control group received conventional treatment, the observation group treated with indomethacin on the preventionof the conventional treatment.The serum amylase levels at different time points before and after surgery, acute pancreatitis and hyperamylasemia&lt;/b13&gt;</p><p>author Units:4732b4Nanyang,Henan Zhongnan Industrial Co., Ltd. Staff Hospital surgery</p><p>oftwo groups were compared.ResultsTheserum amylase levels of the observation group and the control group after 2 H, after H, H PostoperativE were higlier than the preoperative, the degree of elevation of the Obsen<sup>T</sup>ation Group was smaller than the conTrol Group, the difference was statistically significance (P 0.05).The incidence of acute pancreatitisand hyperamylasemia of the Obsen<sup>7</sup>ation Group were lower than the control groUp, the difference was statistically significant (^ 0.05).conclusionindomethacin can be effective in preventing POST-ERCP acutePancreatitis and reduce the incidence of hyperamylasemia, can significantly lower blood.</p>


2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Yongjie Wang ◽  
Hongxing Zhang ◽  
Wangbo Cao

Objective: To study the effects of Shensong Yangxin capsules and amiodarone on heart rate variability indexes and inflammatory factors in the treatment of patients with arrhythmia. Methods: The research subjects were selected patients with arrhythmia admitted in our hospital's department from October 2018 to October 2019, and a total of 70 patients were divided into two groups. 35 subjects in the control group were treated with amiodarone alone, and 35 subjects in the observation group were treated with Shensongyangxin capsule in combination with amiodarone for comparisons in treatment effects, heart rate variability indices, inflammatory factors, and adverse reactions. Results: After observation, the treatment efficiency in the observation group was higher than that in the control group (P<0.05). Before treatment, there was no difference in heart rate variability indices between the two groups (P>0.05), after treatment, the improvement in patients of the observation group was better than that of the control group (P<0.05). After treatment, the inflammatory factors of the two groups of patients decreased, and the indicators of the observation group were comparably lower than those of the control group (P<0.05). In the comparison of adverse reactions, the observation group showed a lower incidence of adverse reactions after treatment than the control group (P<0.05). Conclusion: In the treatment of patients with arrhythmia, the combined use of Shensong Yangxin capsules and amiodarone has more significant therapeutic effects, which can effectively improve the patient's heart rate variability indices, reduce the inflammatory factors, and relieve the symptoms in patients. The incidence of adverse reactions is low and the safety is quite high, therefore it has great value in clinical applications.


Author(s):  
Huanlin Huang ◽  
Zheng Zhong ◽  
Xinyi Zhang ◽  
Jizhou Wang ◽  
Yujie Li ◽  
...  

Background: Fear is one of the most widely studied emotions and is closely associated with the autonomic nervous system (ANS). Previous studies have proven that acupuncture directly impacts the ANS, influences the heart rate (HR) and the heart rate variability (HRV) and exerts other effects. The aim of this study was to explore the effect of Jianshi (PC5) and Neiguan (PC6) electro-acupuncture on HRV during fear-invoking auditory stimulation using an Actiheart ECG recorder. Materials and Methods: Two hundred healthy subjects were recruited. Using a random number table, subjects were grouped for exposure to fear-invoking auditory stimulation (n=40) or neutral auditory stimulation (n=40). After determining that our fear-invoking auditory stimulation produced the fear emotion, the other 120 subjects were similarly divided into an electro-acupuncture (EA group) and a control group that received PC5 and PC6 electro-acupuncture or no intervention. Results: The fear score of the fear-invoking auditory group was significantly higher than that of the neutral auditory group. The EA group showed higher SD, RMSSD, and high frequency (HF) components of HRV than those of the control group. Conclusion: The primary result suggests that PC5 and PC6 electro-acupuncture affects cardiac autonomic neural regulation, mainly via the parasympathetic system, in subjects exposed to fear-invoking auditory stimulation.


2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Jiayi Lu

Objective — To investigate the efficacy of acupuncture and moxibustion in the treatment of chronic functional constipation and the observation of adverse reactions in patients. Methods — A total of 88 patients with chronic functional constipation who were treated from June 2019 to March 2021 were selected as the subjects, and the patients were divided into control group with 44 patients and observation group with 44 patients according to a random number table.The control group was given conventional western medication, and the observation group was given acupuncture based treatment. The scores for clinical symptom and the incidence of adverse reactions were compared between the two groups after treatment. Results — After treatment, the symptom scores of frequency of abdominal pain, incomplete sense of defecation, abdominal distension and difficulty in defecation in the observation group were all lower than those in the control group (P < 0.05). After treatment, the total incidence of adverse reactions of abdominal distension, spasmodic abdominal pain, borborygmus and dizziness in observation group was 4.55%, which was significantly lower than that in control group, 22.73% (P < 0.05). Conclusion — Acupuncture and moxibustion therapy is more effective than conventional western medicine therapy in treatment of chronic functional constipation,which effectively improve the clinical symptoms of patients, reduce the occurrence of adverse reactions, as as result, it is worthy of promotion and universal application.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Shimin Miao

Objective: To investigate the effects of Pulmicort Respules, Ventolin combined with methylprednisolone in the adjuvant treatment of bronchiolitis in children. Methods: A total of 100 children with bronchiolitis in our hospital from March 2018 to March 2020 were selected and divided into 2 groups with 50 cases in each group by using random number table. Both groups received conventional treatment. Based on this, the control group was given Pulmicort Respules and Ventolin, and the observation group was given methylprednisolone in combination with the conventional regimens on the basis of the control group treatment, the course of treatment was 5 days. The levels of inflammatory factors [tumor necrosis factor-a (TNF-a), interleukin 6 (IL-6)] and the time to symptom disappearance before and after treatment were compared and analyzed between the two groups. Results: After treatment, the levels of serum TNF-a and IL-6 in the two groups decreased, and the observation group was lower than the control group, the difference was statistically significant (P<0.05); the disappearance of pulmonary moist rales, lung wheezing, cough and wheezing in the observation group were all earlier than the control group, the difference was statistically significant (P<0.05). Conclusion: Pulmicort Respules, Ventolin combined with methylprednisolone is effective in adjuvant treatment of bronchiolitis in children, which can reduce inflammation and promote the recovery of children.


2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Liang Gao ◽  
Shuang Xu ◽  
Jun Liu ◽  
Wei Luo ◽  
Jing Chen

Objective: To investigate the effect of vault on conjunctiva combined with fascia sheath suspension on the mobility and aesthetics of eyelid in patients with ptosis. Methods: A total of 80 patients with ptosis who were admitted to our hospital from January 2017 to January 2019 were selected as the subjects. They were divided into 2 groups with random number table method, 40 cases each. The control group was treated with modified single-incision frontalis fascia flap suspension, and the observation group was treated with vault on conjunctiva combined with fascia sheath suspension. The eyelid margin activity, aesthetics and complications were compared between the two groups. Results: The eyelid margin activity of the observation group after treatment was higher than that of the control group, the difference was statistically significant (P<0.05); the aesthetic satisfaction of the observation group after treatment was 95.00% (38/40) higher than that of the control group 70.00% (28/40) The difference was statistically significant (P<0.05); the incidence of complications in the observation group was 2.50% (1/40) lower than that in the control group 20.00% (8/40), and the difference was statistically significant (P<0.05). Conclusion: Patients with ptosis are treated with superior conjunctival fornix combined with fascia sheath suspension, which can improve the mobility of eyelid margin, and it is more beautiful and has less complications.


2021 ◽  
Vol 7 (3) ◽  
pp. 12
Author(s):  
Ze Wang ◽  
Li Du ◽  
Mengyuan Hu

Objective: To explore the effect of Guhong injection combined with atorvastatin on CHD patients with angina pectoris and its influence on hemorheology and oxidative stress.Methods: 80 CHD patients with angina pectoris admitted to our hospital from December 2018 to December 2019 were randomly divided into the observation group (40 cases) and the control group (40 cases) by use of the random number table. The patients in the control group were treated with atorvastatin, while those in the observation group were treated with Guhong injection on the basis of the control group. The course of treatment was 2 weeks for each group. The treatment effect, the frequency of angina pectoris seizure and its duration before and after treatment, the changes of hemorheology indexes and oxidative stress and the occurrence of adverse reactions were compared between the two groups.Results: the total effective rate of the observation group (92.50%) was higher than that of the control group (70.00%) (p < .05). The frequency of angina pectoris seizure and its duration in these two groups after treatment were lower than those before treatment (Observation group: t = 25.588, 23.009; Control group: t = 16.587, 16.263; p < .05); After treatment, the frequency of angina pectoris seizure and its duration in the observation group were lower than those in the control group (t = 15.191, 9.425; p < .05). In the observation group, the hemorheology indexes after treatment were lower than those before treatment (t = 6.742, 15.224, 6.983, 23.537, p < .05); the hemorheology indexes after treatment in the observation group were lower than those in the control group (t = 5.201, 13.913, 5.539, 13.745; p < .05). In the observation group, the level of serum SOD after treatment was higher than that before treatment, while the levels of LPO and MDA after treatment were lower than those before treatment (t = 10.839, 6.924, 8.466; p < .05); the level of serum SOD after treatment in the observation group was higher than that in the control group, while the levels of LPO and MDA after treatment in the observation group were lower than those in the control group (t = 6.171, 6.432, 5.394; p < .05). The incidence of adverse reactions in the observation group was lower than that in the control group (p < .05).Conclusions: Guhong injection combined with atorvastatin has an obvious clinical effect on CHD patients with angina pectoris, and it can improve hemorheology indexes and oxidative stress reaction with fewer adverse reactions.


2021 ◽  
Vol 7 (5) ◽  
pp. 3022-3028
Author(s):  
Fei Guo ◽  
Yongjun Wang ◽  
Shenghui Liu ◽  
Junrong Cao

To investigate the effect of B-ultrasound-guided nerve block on analgesia and sedation in patients with acute cholecystitis undergoing puncture and drainage. Methods 96 patients with acute cholecystitis who underwent puncture and drainage from May 2018 to November 2020 were randomly divided into control group and observation group by random number table method, with 48 cases in each group. The patients in the control group were anesthetized by local infiltration. The patients in the observation group were anesthetized by B-ultrasound-guided nerve block. Heart rate, blood pressure, analgesia score, sedation score, and oxidative stress level were compared between the two groups. Results At the time of puncture (T2), heart rate (HR) and mean arterial pressure (MAP) in the two groups were significantly lower than those before operation (T1) (P<0.05); at the end of operation (T3), HR and MAP in the control group were significantly higher than those at T1 (P<0.05); at T2, HR and MAP in the observation group were significantly higher than those in the control group (P<0.05); at T3, HR and MAP in the observation group were significantly lower than those in the control group (P<0.05). AtT2 and T3, Ramsay sedation score in both groups was significantly lower than that at T1 (P<0.05), while Ramsay score in the observation group was significantly higher than that in control group (P<0.05); atT2 and T3, visual analog scale (VAS) pain score in both groups was significantly higher than that at T1 (P<0.05), while VAS score in the observation group was significantly lower than that in the control group (P<0.05). After operation, the levels of serum malondialdehyde (MDA) and superoxide dismutase (SOD) in the two groups were significantly higher than those before operation (P<0.05), and the levels of serum total antioxidant capacity (T-AOC) were significantly lower than those before operation (P<0.05); after operation, the levels of serum SOD and T-AOC in the observation group were significantly higher than those in the control group (P<0.05), and the levels of MDA in the observation group were significantly lower than those in the control group (P>0.05). Conclusion B-ultrasound-guided nerve block anesthesia can maintain the stable hemodynamic index of patients with acute cholecystitis undergoing puncture and drainage therapy, improve the analgesic and sedative effect and reduce the oxidative stress response of the body.


2017 ◽  
Vol 26 (2) ◽  
pp. 116-21
Author(s):  
Arif H.M. Marsaban ◽  
Aldy Heriwardito ◽  
I G.N.A.D. Yundha

Background: Increased blood pressure and heart rate are the most frequent response to laryngoscopy which sometimes causes serious complications. Laryngoscopy technique and tools modification lessen the nociceptive stimulation, thus preventing hemodynamic response. BURP maneuver is used to lower Cormack-Lehane level, but it can cause additional pain stimulation during laryngoscopy. The aim of this study was to compare the cardiovascular response and the need of BURP maneuver during laryngoscopy between CMAC® and conventional Macintosh.Methods: A randomized, single blinded, control trial was performed to 139 subjects who underwent general anesthesia with endotracheal tube. Subjects were randomised into a control group (conventional Macintosh) and an intervention group (CMAC®). The cardiovascular parameters (systolic, dyastolic, mean arterial pressure, and heart rate) were measured prior to induction (T1). Midazolam 0.05 mg/kg and Fentanyl 2 micrograms/kg were given 2 minutes before the induction. Moreover, they were given propofol 1 mg/kg followed by propofol infusion of 10 mg/kg/hour and Atracurium 0.8–1 mg/kg. After TOF-0 cardiovascular parameters (T2) were remeasured, it was proceeded to laryngoscopy. When Cormack-Lehane 1–2 was reached (with or without BURP maneuver), cardiovascular parameters were measured again (T3).Results: Unpaired T-test showed that cardiovascular response during laryngoscopy were significantly lower in the intervention group compared to the control group (p<0.05). The need of BURP maneuver was significantly lower in the CMAC® group compared to the Convensional Macintosh group (13.9% vs 40.3%; p<0.05).Conclusion: Cardiovascular response and BURP maneuver during laryngoscopy with CMAC® were significantly lower compared to conventional Macintosh.


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