scholarly journals Observation on Curative Effect and Adverse Reaction of Acupuncture and Moxibustion in Treating Chronic Functional Constipation

2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Jiayi Lu
Keyword(s):  
Abdominal Pain ◽  
Adverse Reactions ◽  
Clinical Symptoms ◽  
Functional Constipation ◽  
Abdominal Distension ◽  
Control Group ◽  
Observation Group ◽  
Acupuncture And Moxibustion ◽  
Total Incidence ◽  
Universal Application

Objective — To investigate the efficacy of acupuncture and moxibustion in the treatment of chronic functional constipation and the observation of adverse reactions in patients. Methods — A total of 88 patients with chronic functional constipation who were treated from June 2019 to March 2021 were selected as the subjects, and the patients were divided into control group with 44 patients and observation group with 44 patients according to a random number table.The control group was given conventional western medication, and the observation group was given acupuncture based treatment. The scores for clinical symptom and the incidence of adverse reactions were compared between the two groups after treatment. Results — After treatment, the symptom scores of frequency of abdominal pain, incomplete sense of defecation, abdominal distension and difficulty in defecation in the observation group were all lower than those in the control group (P < 0.05). After treatment, the total incidence of adverse reactions of abdominal distension, spasmodic abdominal pain, borborygmus and dizziness in observation group was 4.55%, which was significantly lower than that in control group, 22.73% (P < 0.05). Conclusion — Acupuncture and moxibustion therapy is more effective than conventional western medicine therapy in treatment of chronic functional constipation,which effectively improve the clinical symptoms of patients, reduce the occurrence of adverse reactions, as as result, it is worthy of promotion and universal application.

scholarly journals Artificial Intelligence-Based CT Images in Analysis of Postoperative Recovery of Patients Undergoing Laparoscopic Cholecystectomy under Balanced Anesthesia

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Manyun Bai ◽  
Renzhong Guo ◽  
Qian Zhao ◽  
Yufang Li
Keyword(s):  
Artificial Intelligence ◽  
Abdominal Pain ◽  
Recovery Time ◽  
Adverse Reactions ◽  
Abdominal Distension ◽  
Control Group ◽  
Bowel Sound ◽  
Observation Group ◽  
Reconstruction Accuracy ◽  
Balanced Anesthesia

To explore whether preoperative processing can promote the recovery of gastrointestinal function after laparoscopic cholecystectomy (LC) surgery, in the study, an artificial intelligence-based algorithm was used to segment the CT images to assist doctors in decision making. The patients were divided into observation group (balanced anesthesia) and control group (general anesthesia) with SPSS. The observation group received balanced anesthesia half a day before the operation. The method of balanced anesthesia was to induce 0.2 mg/kg midazolam, 3 mg/kg propofol, 2 μg/kg remifentanil, 0.2 mg/kg vecuronium, 4∼5 mg/(kg·h) propofol, and 9∼11 μg/(kg·h) remifentanil continuous intravenous infusion to maintain anesthesia, and it was stopped once the patient defecated; the control group had general anesthesia in the afternoon after the operation, and it was stopped once the patient defecated. The time before the first exhaust and defecation after the surgery as well as the recovery time of bowel sound was recorded, and the degree of abdominal pain, abdominal distension, and gastrointestinal adverse reactions was evaluated at 22 hours, 46 hours, and 70 hours after the surgery. It was found that the accuracy of the artificial intelligence-based segmentation algorithm was 81%. The reconstruction accuracy of multidimensional liver could be observed at any angle, and the reconstruction accuracy was not lower than the resolution of original input CT. The calculation error was less than 9%, and the volume of whole liver, liver segment, preresection liver, and residual liver was less than 9%. The simulation accuracy of virtual liver surgery was not lower than the resolution of original input CT. The time before the first exhaust and defecation was shorter in the observation group versus the control group ( P  < 0.05). The recovery time of bowel sound in the observation group was shorter than that in the control group ( P  < 0.05). There was a significant difference in the scores of abdominal distension between the two groups at 22 h and 46 h after surgery ( P  < 0.05). It suggested that both the observation group and the control group could improve the symptoms of gastrointestinal adverse reactions after surgery. Nevertheless, balanced anesthesia can shorten the time before the first exhaust and defecation after surgery and promote the recovery of postoperative bowel sound. Furthermore, balanced anesthesia can alleviate abdominal distension, abdominal pain, and gastrointestinal adverse reactions, which should be promoted in clinic.

scholarly journals Curative effect of Omeprazole under different treatment courses in treatment of children with PU and HP infection and its influence on inflammatory factors

2020 ◽  
Vol 36 (7) ◽  
Author(s):  
Shaohui Zhang ◽  
Yuan-da Zhang ◽  
Qing-wei Dong ◽  
Fang Gu
Keyword(s):  
Adverse Reactions ◽  
Eradication Rate ◽  
Clinical Symptoms ◽  
Statistical Significance ◽  
Symptom Relief ◽  
Inflammatory Factors ◽  
Controlled Study ◽  
Control Group ◽  
Observation Group ◽  
Curative Effect

Objective: To compare curative effect and safety of omeprazole under different treatment courses in treatment of children with peptic ulcer (PU, diameter ≤1.0cm) and helicobacter pylori (HP) infection and its influence on inflammatory cytokines. Methods: The study was a randomized controlled study and conducted at Baoding children’s hospital from June 2015 to June 2018. In this study 100 PU children with positive HP were chosen and classified into two groups at random. The 58 cases in the observation group were given omeprazole + amoxicillin + clarithromycin, and the antibiotics were not used two weeks later. Then, omeprazole was used to treat for two weeks. 42 cases in the control group were given omeprazole + amoxicillin + clarithromycin for two weeks. Curative effect, HP eradication rate, clinical symptoms, incidence of adverse reactions, level of serum inflammatory cytokine interleukin-6 (IL-6) and level of tumor necrosis factor-a (TNF-a) in two groups were compared. Results: Total effective rate, HP eradication rate and clinical symptom relief of observation group were better than those of control group, and the differences showed statistical significance (P<0.05). The differences of two groups in the incidence of adverse reactions had no statistical significance (P<0.05). Serum IL-6 level and TNF-a level of observation group were significantly lower than those of control group and before the treatment, and the differences had statistical significance (P<0.05). Conclusion: The application of omeprazole in treatment of PU patients with positive HP for four weeks can significantly improve PU cure rate and HP eradication rate, relieve clinical symptoms and reduce inflammatory response, so it deserves to be promoted clinically. doi: https://doi.org/10.12669/pjms.36.7.3048 How to cite this:Zhang S, Zhang Y, Dong Q, Gu F. Curative effect of Omeprazole under different treatment courses in treatment of children with PU and HP infection and its influence on inflammatory factors. Pak J Med Sci. 2020;36(7):---------. doi: https://doi.org/10.12669/pjms.36.7.3048 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Benefits of a Nanosilver Nasal Spray for Postoperative Care of Patients with Chronic Rhinosinusitis

2020 ◽  
Vol 20 (12) ◽  
pp. 7342-7346
Author(s):  
Xia Zhao ◽  
Chenghua Zhao ◽  
Xiaoning Zhang ◽  
Liqun Xing
Keyword(s):  
Chronic Rhinosinusitis ◽  
Adverse Reactions ◽  
Clinical Symptoms ◽  
Metallic Silver ◽  
Control Group ◽  
Observation Group ◽  
Pathogenic Microorganisms ◽  
Post Surgery ◽  
Nanosilver Particles ◽  
Symptoms And Signs

To explore tending to patients with chronic rhinosinusitis using a nanosilver compound. From February 2014 to August 2016, 112 surgical patients with chronic rhinosinusitis were randomly divided into an observation group and a control group. Patients in the observation group were given antibiotics, care to retain hemostasis, and other treatment after surgery. Patients in the observation group were administered treatment with bonbijing nano antibacterial water spray post-surgery. The progress of both groups recorded. Nanosilver is metallic silver of nanometer size. Nanosilver particles in the spray are approximately 25 nm in diameter, strongly inhibit growth of or kill dozens of pathogenic microorganisms, e.g., Escherichia coli. Postoperative pain in patients in the observation group was less than pain in the control group patients (p < 0.05). Symptom and sign scores in observation group patients were lower than scores in control group patients (p < 0.05). Incidence of adverse reactions and complications was also lower in observation group patients (p<0.05). Use of nanosilver for tending to patients with chronic rhinosinusitis after surgery can significantly improve clinical symptoms and signs, and reduce adverse reactions and complications.

Efficacy of Shenqi Runchang Tongbian Decoction in Treatment of Children with Constipation and Its Effect on Clinical Symptoms of Children

2021 ◽  
Vol 7 (5) ◽  
pp. 1551-1557
Author(s):  
Huang Yuanqin ◽  
Li Xiaoqian ◽  
he Huizhen ◽  
Li Lin ◽  
Xu Hui
Keyword(s):  
Abdominal Pain ◽  
Symptom Score ◽  
Clinical Symptoms ◽  
Abdominal Distension ◽  
Control Group ◽  
Study Group ◽  
Secondary Symptom ◽  
Significant Difference ◽  
Defecation Frequency

To investigate the efficacy of Shenqi Runchang Tongbian Decoction in the treatment of children with constipation and its effect on the clinical symptoms of children. Methods: From January 2016 to January 2020, 100 patients with constipation were randomly divided into two groups. The control group was treated with lactulose oral solution, and the study group was treated with Shenqi Runchang Tongbian Decoction. Both groups were administered with drugs for 14 days, and the two groups were followed up on the 28th day. The effectiveness of the two groups was compared before treatment and during follow-up. The changes of various symptom scores were compared before treatment, after treatment and during follow-up, and the changes of primary symptom score, secondary symptom score and total score were compared before treatment, after treatment and during follow-up. Results: After treatment, the effectiveness of the study group was higher than that of the control group at follow-up (P <0.05). After treatment and during the follow-up, the scores of facial color, lips, sleep, urination, hand-foot-heart-chest, appetite, halitosis, abdominal distension and abdominal pain, defecation duration, defecation difficulty, defecation frequency and stool property of the two groups were lower than those before treatment (P < 0.05). There was no significant difference in the scores of facial color, sleep, urination and hand-foot-heart-chest symptoms before and after treatment of the control group and the study group (P > 0.05). There was no significant difference in the scores of facial color, lips, sleep, urination and hand-foot-heart-chest symptoms before treatment and during follow-up between the control group and the study group (P > 0.05). The scores of lip symptoms after treatment in the study group were lower than those in the control group (P < 0.05). The scores of appetites, halitosis, abdominal distension and abdominal pain, defecation duration, defecation difficulty, defecation frequency, stool property after treatment and during follow-up in the study group were lower than those in the control group (P <0.05). The total score, the secondary symptom score and the primary symptom score of the two groups before treatment and during follow-up were lower than those before treatment (P < 0.05). The total score, the secondary symptom score and the primary symptom score in the study group were lower than those in the control group after treatment and during follow-up (P < 0.05). Conclusion: The treatment of children with constipation with Shenqi Runchang Tongbian Decoction can improve the secondary symptoms and primary symptoms of children and improve the comprehensive curative effect, especially in the aspects of improving appetite, halitosis, abdominal distension and abdominal pain, defecation duration, defecation difficulty, defecation frequency and stool property. It can effectively enhance the gastrointestinal function and promote the rehabilitation of children. It is worthy of being popularized in clinical practice.

scholarly journals Analysis of the Effect of Anesthetics Comprising of Remifentanil Combined with Propofol During Thyroidectomy

2019 ◽  
Vol 3 (5) ◽  
Author(s):  
Qikai Liao
Keyword(s):  
Heart Rate ◽  
Mean Arterial Pressure ◽  
Adverse Reactions ◽  
Random Number ◽  
Control Group ◽  
Observation Group ◽  
Hemodynamic Parameters ◽  
Intravenous Anesthesia ◽  
Total Incidence ◽  
Random Number Table

Objective: To analyze the anesthetic effect of remifentanil combined with propofol during thyroidectomy. Methods: A total of 70 patients who underwent thyroidectomy during November 2018 to November 2019 in Chongqing Eleventh People's Hospital were selected and recruited. These patients were divided into control group and observation group by random number table method. Each group consisted of 35 patients. The patients in the control group was given intravenous anesthesia comprising of propofol combined with intermittent fentanyl anesthesia, whereas the patients in the observation group was given intravenous anesthesia comprising of remifentanil combined with propofol. Results: The heart rate and mean arterial pressure of the observation group after anesthesia for 30 minutes were lower than those of the control group, and the differences were statistically significant (P < 0.05). The total incidence of adverse reactions in the observation group was lower than that of the control group, and the differences were statistically significant (P < 0.05). Conclusion: Remifentanil combined with propofol is effective in thyroidectomy. This combination can reduce the risk of adverse reactions and maintain stable hemodynamic parameters.

scholarly journals Application of simple head cooling combined with gangliosides in neonatal hypoxic-ischemic encephalopathy

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Zhen Zhan ◽  
Huanhuan Cheng ◽  
Xianhong Lin ◽  
Yangyang Meng ◽  
Liying Dai ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Adverse Reactions ◽  
Clinical Symptoms ◽  
Clinical Performance ◽  
Hypoxic Ischemic Encephalopathy ◽  
Control Group ◽  
Observation Group ◽  
Head Cooling ◽  
Disturbance Of Consciousness ◽  
Ischemic Encephalopathy

Objective To investigate the effect of simple head cooling combined with ganglioside therapy on neonatal hypoxic-ischemic encephalopathy (HIE) and its clinical efficacy. Methods A total of 100 children with HIE admitted in the neonatal ward of our hospital from August 2018 to October 2020 were selected as the research objects, and were divided into control group and observation group according to the random number table method, with 50 cases in each group. The control group was treated with gangliosides, and the observation group was treated with simple head cooling combined with gangliosides. Observe and compare the clinical performance improvement time, the level of relevant hematological examination indexes before and after treatment, and the neonatal behavioral neurological assessment (NBNA), clinical efficacy, and adverse reactions. Results The improvement time of convulsions, disturbance of consciousness, pupil changes, hypotonia, and gastrointestinal dysfunction in the observation group was significantly lower than that in the control group (all P＜0.001). After treatment, the NSE, IL-6, CK, CK-MB of the two groups of children were significantly lower than before treatment, and the serum calcium and NBNA scores were significantly higher than before treatment, and the decrease or increase in the observation group was significantly higher than that of the control Group (all P＜0.001). The total effective rate of treatment of children in the observation group (82.00%) was higher than that of the control group (62.00%) (P<0.05). There were no obvious adverse reactions in both groups. Conclusion The simple head cooling combined with gangliosides in the treatment of HIE can improve the clinical symptoms, blood test index levels, and NBNA scores. The clinical effect is clear and superior to the single use of gangliosides.

scholarly journals The Observation of the Curative Effects of Nursing Intervention on the Premature Infant with Jaundice

2015 ◽  
Vol 4 (3) ◽  
pp. 19
Author(s):  
Hui Yang
Keyword(s):  
Premature Infants ◽  
Adverse Reactions ◽  
Clinical Effect ◽  
Serum Bilirubin ◽  
Abdominal Distension ◽  
Nursing Intervention ◽  
Control Group ◽  
Observation Group ◽  
Bilirubin Concentration ◽  
Serum Bilirubin Concentration

<strong>Objective:</strong> To analyze the clinical effect of comprehensive nursing intervention on preterm infant with jaundice. <strong>Methods: </strong>During the treatment in our hospital as the research purpose from January 2004 to January 2014, 94 cases of premature infants were randomly divided into two groups which is control group and observation group. For control group patients, they were given routine nursing while the observation group patients were given comprehensive nursing intervention. These two groups of patients were analyzed with serum bilirubin concentration respectively, the comparison between patient weight and the time of fetal turn yellow and the occurrence of the disease. <strong>Results:</strong> Compared to control group, the serum bilirubin concentration in the observation group was significantly decreased, weight and meconium turned yellow time increased significantly, the incidence of complications such as apnea, abdominal distension and feeding intolerance was significantly lower and the differences were statistically significant (<em>p</em> &lt; 0.05). <strong>Conclusion:</strong> Comprehensive nursing intervention can effectively improve the growth and development of premature infants and recovery, reduce the incidence of adverse reactions, has a significant clinical effect and it is worth promoting.

scholarly journals Comparison of azithromycin and erythromycin in the treatment of mycoplasma pneumonia in children

2019 ◽  
Vol 36 (2) ◽  
Author(s):  
Rui Han ◽  
Qianqian Yu ◽  
Guohui Zhang ◽  
Baoqiang Li ◽  
Shuzhen Han ◽  
...  
Keyword(s):  
Adverse Reactions ◽  
Clinical Symptoms ◽  
Control Group ◽  
Clinical Effects ◽  
Observation Group ◽  
Research Subjects ◽  
Creative Commons ◽  
Significant Difference ◽  
Mycoplasma Pneumonia ◽  
The Difference

Objective: To study and compare the clinical effects of azithromycin and erythromycin on children with mycoplasma pneumonia. Methods: Total 132 children with mycoplasma pneumonia who were admitted to our hospital between November 2017 and September 2018 were selected as the research subjects. All the children were divided into an observation group and a control group according to random number table, 66 each. The observation group was treated with azithromycin, while the control group was treated with erythromycin. The therapeutic effect, incidence of adverse reactions and disappearance time of clinical symptoms were compared between the two groups. Results: The total efficacy of the observation group was 98.04%, and that of the control group was 74.51%; there was a significant difference (X2=7.184, P=0.007). The incidence of adverse reactions in the observation group was 15.69%, significantly lower than that in the control group (41.18%) (X2=6.376, P=0.002). The disappearance of fever, cough, rale and X ray shadow of the observation group was significantly earlier than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: Compared with erythromycin, azithromycin is more effective in the treatment of mycoplasma pneumonia in children. Azithromycin can further shorten the improvement time of clinical symptoms and signs and has few adverse reactions and high safety. It is worth clinical application. doi: https://doi.org/10.12669/pjms.36.2.1441 How to cite this:Han R, Yu Q, Zhang G, Li B, Han S, Li G. Comparison of azithromycin and erythromycin in the treatment of mycoplasma pneumonia in children. Pak J Med Sci. 2020;36(2):---------. doi: https://doi.org/10.12669/pjms.36.2.1441 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Analysis on Nursing Effect of Octreotide on Acute Pancreatitis

2021 ◽  
Vol 7 (4) ◽  
pp. 300-307
Author(s):  
Chenxia Wu ◽  
Li He
Keyword(s):  
Acute Pancreatitis ◽  
Clinical Symptoms ◽  
Nursing Intervention ◽  
Effective Rate ◽  
Occurrence Rate ◽  
Control Group ◽  
Observation Group ◽  
Clinical Value ◽  
Nursing Satisfaction ◽  
Satisfaction Scale

To explore the clinical value of octreotide therapy and nursing intervention in patients with acute pancreatitis. 120 patients with acute pancreatitis admitted to the Department of Digestive Medicine from June 2018 to August 2019 were selected. Two groups of patients were treated with octreotide. They were randomly divided into observation group (intensive nursing intervention) and control group (routine nursing) with 60 patients in each group. Compared with the control group (81.67%), the total effective rate (93.33%) was higher in the observation group (P<0.05%); After treatment, C reactive protein, lactate dehydrogenase, WBC and hemodiastase of patients in the observation group were better than those in the control group (P<0.05); compared with the control group (18.33%), the occurrence rate of hypoglycemia in the observation group (6.67%) was lower (P<0.05%); At the same time, the Nursing Satisfaction Scale of the observation group (95.00%) was higher than that of the control group (78.33%), (P<0.05%). Patients with acute pancreatitis treated with octreotide and strengthened nursing intervention can obtain more obvious therapeutic effect, so that the clinical symptoms and related laboratory indicators of patients have been significantly improved. At the same time, the clinical value was significant with a lower occurrence rate of hypoglycemia and higher nursing satisfaction scale.

scholarly journals Meta-Analysis of Clinical Efficacy and Safety of Ligustrazine in the Treatment of Idiopathic Pulmonary Fibrosis

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Xiaozheng Wu ◽  
Wen Li ◽  
Zhenliang Luo ◽  
Yunzhi Chen
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Clinical Efficacy ◽  
Adverse Reactions ◽  
Clinical Symptoms ◽  
Gas Analysis ◽  
Control Group ◽  
Efficacy And Safety ◽  
Arterial Blood Gas ◽  
Arterial Blood

Objective. To systematically review the efficacy and safety of Ligustrazine in the treatment of idiopathic pulmonary fibrosis (IPF). Methods. The electronic literature databases (PubMed, EMbase, CNKI, WanFang database, and VIP) were retrieved through a computer to find out the randomized controlled trials (RCT) of Ligustrazine in the treatment of IPF according to the inclusion/exclusion criteria screening test. Cochrane’s bias risk table was also used to evaluate the quality of the study and to extract effective data. RevMan 5.3 was used for statistical analysis. Results. A total of 7 RCTs (a total of 366 patients, including 196 in experimental and 170 in control group). Compared with the control group, Ligustrazine could improve the clinical symptoms ([OR] = 2.20, 95% CI [1.40, 3.46], P = 0.0006 ), lung function (VC % [MD] = 3.92, 95% CI [0.68, 7.17], P = 0.02 ), (TLC% [MD] = 4.94, 95% CI [0.37, 9.52], P = 0.03 ), the pulmonary diffusion function (DLCO % [MD] = 9.12, 95% CI [5.70, 12.55], P < 0.00001 ), and arterial blood gas analysis (PaO2 [MD] = 7.11, 95% CI [1.96, 12.25], P = 0.007 ) (PaCO2 [MD] = −2.42, 95% CI [−4.36, −0.49], P = 0.01 ) of IPF patients, respectively. However, FEV1/FVC % ([MD] = 9.37, 95% CI [−1.23, 19.97], P = 0.08 ) and adverse reactions ([MD] = 0.35, 95% CI [0.02, 5.36], P = 0.45 ) were not significantly improved. Conclusion. Ligustrazine has certain clinical efficacy in the treatment of IPF, but the safety of applying it and the adverse reactions need to be further analyzed and determined. It can be considered as a new alternative and complementary medicine to be promoted and recommended for use in medical units in various countries in the world and it solved the difficult problem of conventional drug treatment of IPF; therefore, more research strength can be put in the treatment of the pathological mechanism of IPF for further exploration. The study was registered under registration number CRD42020193626.

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