scholarly journals Improvement of transmucosal absorption of drugs in drug delivery system (DDS) 3. The functional role of transporters in the intestine and their contribution to drug absorption

2005 ◽  
Vol 20 (4) ◽  
pp. 424-432 ◽  
Author(s):  
Mariko Morishita
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Absorption ◽  
Functional Role

Role of excipients in successful development of self-emulsifying/microemulsifying drug delivery system (SEDDS/SMEDDS)

2012 ◽  
Vol 39 (1) ◽  
pp. 1-19 ◽  
Author(s):  
Md. Akhlaquer Rahman ◽  
Arshad Hussain ◽  
Md. Sarfaraj Hussain ◽  
Mohd. Aamir Mirza ◽  
Zeenat Iqbal
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Successful Development

scholarly journals A REVIEW ON NASAL DRUG DELIVERY SYSTEM AND ITS CONTRIBUTION IN THERAPEUTIC MANAGEMENT

2019 ◽  
Vol 12 (1) ◽  
pp. 40
Author(s):  
Sulaiman Alnasser
Keyword(s):  
Drug Delivery ◽  
Nasal Cavity ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Absorption ◽  
Delivery Systems ◽  
Nasal Delivery ◽  
Present Review ◽  
Drug Formulations ◽  
Nasal Drug Delivery

Nasal drug delivery has received a great deal of attention as a convenient, reliable, and promising method for the systemic administration of drugs. It is especially for those molecules which are ineffective orally and only effective if administered by injection. The nasal route of drug delivery has advantages over the other alternative systems of non-invasive drug administration. The present review describes nasal delivery systems in recognizing to its potential and limits. The present review is an attempt to provide some information concerning nasal drug delivery system such as limitations, advantages, mechanism of drug absorption, anatomy of nasal cavity, factors affecting of nasal drug delivery, strategies to enhance nasal absorption, strategies to extend duration of drug formulations within the nasal cavity, leading to improved nasal drug absorption, novel drug formulations, sorts of nasal drug delivery system with uses of nasal drug delivery in various diseases, and recent advancement of nasal delivery systems.

scholarly journals Nanotech drug delivery system: The perfect physio-Chemical deal for biological command

2021 ◽  
Vol 9 (2) ◽  
pp. 73-80
Author(s):  
Yogranjan Singh ◽  
Kaustubh Gurnani ◽  
G. K. Satpute
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Drug Delivery System ◽  
Delivery System ◽  
Conventional Therapy ◽  
Therapeutic Agents ◽  
Prime Concern ◽  
Key Techniques ◽  
Near Future

The application of nanotechnology in drug delivery is offering several exhilarating possibilities not only in healthcare but also in agriculture. Nanoparticles combined with the therapeutic agents have a proven edge over problems associated with conventional therapy; however, some issues like side effects and toxicity are still under debate and are of prime concern in utilization in biological systems. Herein, we discuss the role of nanotech drug delivery system mostly in animal and plants- highlighting the comparative accounts of the key techniques for designing of drug in animals and plants, the challenges therein, the important nanoparticles being used in both the area and prospects of the field in the near future.

scholarly journals APPROACHES AND ROLE OF PROTEIN BASED NANOPARTICLES IN DRUG DELIVERY SYSTEM: A REVIEW

2019 ◽  
Vol 6 (2) ◽  
pp. 1879-1887
Author(s):  
Shayeri Chatterjee ◽  
◽  
Beduin Mahanti ◽  
Subhabrota Majumdar ◽  
Rana Mazumder
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
System A

A Review on Oral Liquid as an Emerging Technology in Controlled Drug Delivery System

2018 ◽  
Vol 24 (13) ◽  
pp. 1349-1356 ◽  
Author(s):  
Sangmesh Raosaheb Torne ◽  
Angappan Sheela ◽  
N.C. Sarada
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Dosage Form ◽  
Related Factors ◽  
Additional Advantage ◽  
Controlled Drug Delivery System ◽  
Oral Liquid ◽  
Liquid Dosage Form

Background: The Oral Liquid Drug Delivery System (OLDDS) remains the primary choice of dosage form, though challenging, for the pharmaceutical scientists. In the last two decades, Oral Liquid Controlled Release (OLCR) formulation has gained a lot of attention because of its advantages over the conventional dosage forms. Method: The world of nanotechnology has paved multiple ways to administer the drug through oral cavity in liquid dosage form with an additional advantage of control over the release. In the current study, the various approaches towards the same have been discussed comprehensively to understand the different mechanisms of OLCR. Conclusion: This review also emphasizes on the existing techniques and the developments that have been made to improve on its efficacy including various formulation related factors. It also provides valuable insights into the role of polymers in the development of OLCR formulation that can be used in the management of Gastroesophageal Reflux Disease (GERD).

Self-emulsifying Drug Delivery System Improve Oral Bioavailability: Role of Excipients and Physico-chemical Characterization

2020 ◽  
Vol 8 (4) ◽  
pp. 290-301
Author(s):  
Yujin Zhu ◽  
Jing Ye ◽  
Quan Zhang
Keyword(s):  
Drug Delivery ◽  
Physicochemical Property ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Bioavailability ◽  
Water Soluble ◽  
Oral Drug ◽  
Scale Production ◽  
Drug Bioavailability

: Self-emulsifying drug delivery system (SEDDS) is a kind of solid or liquid formulation composed of drugs, oil, surfactant and cosurfactant. It could form a fine emulsion (micro/nano) in the gastrointestinal tract after oral administration. Later on, the formed emulsion is absorbed through the lymphatic pathway. The oral bioavailability of drugs in SEDDS would be improved for bypassing the first-pass effect of the liver. Therefore, SEDDS has become a vital strategy to increase the oral bioavailability of poor watersoluble drugs. In addition, there is no aqueous phase in SEDDS, thus SEDDS is a homogeneous system, consequently being suitable for large-scale production and more stable than conventional emulsion. However, the role of formulation aspects in the biological property of SEDDS is not fully clear. In order to prepare the satisfying SEDDS to improve oral drug bioavailability, we need to fully understand the various factors that affect the in vivo behavior of SEDDS. In this review, we would explore the role of ingredient (drugs, oils, surfactant and cosurfactant) of SEDDS in increasing oral drug bioavailability. We would also discuss the effect of physicochemical property (particle size and zeta potential) of SEDDS on the oral drug bioavailability enhancement. This review would provide an approach to develop a rational SEDDS to improving oral drug bioavailability. Lay Summary: Self-emulsifying drug-delivery system (SEDDS) has been proven to be promising in ameliorating the oral bioavailability of poor water-soluble drugs. This review highlighted the influence of excipients and physicochemical property of SEDDS on the formation of emulsion and the oral absorption of drugs in the body.

Role of size of drug delivery carriers for pulmonary and intravenous administration with emphasis on cancer therapeutics and lung-targeted drug delivery

RSC Advances ◽  
2014 ◽  
Vol 4 (62) ◽  
pp. 32673-32689 ◽  
Author(s):  
Chetna Dhand ◽  
Molamma P. Prabhakaran ◽  
Roger W. Beuerman ◽  
R. Lakshminarayanan ◽  
Neeraj Dwivedi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Intravenous Administration ◽  
Targeted Drug Delivery ◽  
Cancer Therapeutics ◽  
Drug Carriers ◽  
Design Parameters ◽  
Targeted Drug

The design of a drug delivery system and the fabrication of efficient, successful, and targeted drug carriers are two separate issues that require slightly different design parameters.

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