Morphological Study of The Pancreas and Duodenum in Adult Guinea Pigs (Cavia porcellus)

The present study aimed to investigate the morphological features of the pancreas and duodenum of theadult males and females guinea pigs. Eight animals of each sex were collected to conduct this project.The selected organs were photographed in situ and macro morphometric measurements were conductedon them. Gross findings revealed that the pancreas of guinea pig was of compact type, of two lobes (rightand left) connected by large central part (body). The organ drains the pancreatic secretion toward the lastpart of the ascending duodenum via minor pancreatic duct with absence of major pancreatic duct. Theduodenum of the guinea pig was very short and V-shaped. The beginning of the duodenum containsduodenal papilla in which found central orifice for the exit of bile secretions of the common bile duct. Inconclusions, the present findings showed the presence of only one minor pancreatic duct and such resultwas significantly different than most rodents by having major pancreatic duct. The duodenum in thestudied guinea pigs was characteristically very short and V-shaped differently to other animals that haveU-shaped and long duodenum.

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Family Outbreaks of Nontyphoidal Salmonellosis following a Meal of Guinea Pigs

Case Reports in Infectious Diseases ◽

10.1155/2015/864640 ◽

2015 ◽

Vol 2015 ◽

pp. 1-3

Author(s):

John B. Fournier ◽

Kimberly Knox ◽

Maureen Harris ◽

Michael Newstein

Keyword(s):

Case Report ◽

South America ◽

Guinea Pig ◽

Guinea Pigs ◽

Cavia Porcellus ◽

Andean Region ◽

Human Salmonellosis ◽

Pig Meat

Salmonellaoutbreaks have been linked to a wide variety of foods, including recent nationwide outbreaks. Guinea pig (Cavia porcellus), also known as cuy or cobayo, has long been a popular delicacy and ceremonial food in the Andean region in South America. This case report describes three family outbreaks of nontyphoidal salmonellosis, each occurring after a meal of guinea pigs. We believe this case report is the first to describe a probable association between the consumption of guinea pig meat and human salmonellosis. Physicians should be aware of the association ofSalmonellaand the consumption of guinea pigs, given the increasing immigration of people from the Andean region of South America and the increasing travel to this region.

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Effects of lonomer Cement on Guinea Pig Cochleas

Ear Nose & Throat Journal ◽

10.1177/014556139707600410 ◽

1997 ◽

Vol 76 (4) ◽

pp. 223-230 ◽

Cited By ~ 7

Author(s):

Taisuke Kobayashi ◽

Yasuyuki Hinohira ◽

Masamitsu Hyodo ◽

Goran Bredberg ◽

Edel Alsterborg

Keyword(s):

Hearing Loss ◽

Guinea Pig ◽

Guinea Pigs ◽

Morphological Study ◽

Round Window ◽

Cell Loss ◽

Round Window Membrane ◽

Hair Cell Loss ◽

Ear Surgery ◽

Hearing Thresholds

The inner ear toxicity of ionomeric cement (lonocem®) when used as a reconstructive material in ear surgery was evaluated in 47 guinea pigs used in a morphological study. The cement was implanted on either the promontory, the round window membrane or the stapes. There was no significant hair cell loss compared with the control ear at three weeks, two months or three months after implantation. Using electrocochleography, the hearing thresholds before, and three weeks, two and three months after the implantation were compared in an additional seven animals. No evident hearing loss was observed in any animal during the study period. No morphological or functional evidence for an ototoxic effect of the ionomeric cement was found in this study.

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Measurement of the pH of the Endolymph in the Cochlea of Guinea Pigs

American Journal of Physiology-Legacy Content ◽

10.1152/ajplegacy.1958.194.2.393 ◽

1958 ◽

Vol 194 (2) ◽

pp. 393-395 ◽

Cited By ~ 18

Author(s):

George A. Misrahy ◽

Kenneth M. Hildreth ◽

Leland C. Clark ◽

Edward W. Shinabarger

Keyword(s):

Carbon Dioxide ◽

Guinea Pig ◽

Potassium Chloride ◽

Guinea Pigs ◽

Carbon Dioxide Tension

Using a potassium chloride reference microelectrode and an antimony-Cerroseal alloy active microelectrode, the pH of the perilymph exposed to the atmosphere was found to be 7.8–8.0 and the endolymph in situ 7.3–7.5 in the guinea pig. The acidity of these fluids in situ appears to be very sensitive to changes in carbon dioxide tension.

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115 FIRST SUCCESSFUL PREGNANCY AFTER EMBRYO TRANSFER INTO SYNCHRONIZED FEMALES IN GUINEA PIG (CAVIA PORCELLUS)

Reproduction Fertility and Development ◽

10.1071/rdv24n1ab115 ◽

2012 ◽

Vol 24 (1) ◽

pp. 170

Author(s):

A. Grégoire ◽

F. Peredo ◽

S. León ◽

E. Huamán ◽

A. Allard ◽

...

Keyword(s):

Guinea Pig ◽

Embryo Transfer ◽

Low Income ◽

Guinea Pigs ◽

18Th Century ◽

Tap Water ◽

Uterine Horn ◽

Cavia Porcellus ◽

Research Areas ◽

Transfer Method

The guinea pig (Cavia porcellus) has been used as a laboratory animal since the late 18th century and still remains essential in many research areas. It also plays an important role in the Andes societies as a source of protein for many low-income highlanders and as part of rituals and traditional medicines. Thus, the conservation of genetic diversity is a long-term issue that must be considered. To establish an embryo cryobank, it is necessary to develop a method of embryo transfer. Up to now no pregnancies after surgical embryo transfer into synchronized females have been reported in guinea pigs. The aim of this work was to design a standard embryo transfer method in this species. Eight normally cycling female guinea pigs from the Maria-Marcela Farm (Puente Piedra, Peru), weighing from 1 to 1.5 kg, were used in this study. Females were housed under farming conditions and fed on commercial pellets and tap water ad libitum. Three donor females were superovulated using 15 IU of human menopausal gonadotrophin (hMG, Massone®, Buenos Aires, Argentina) and mated as soon as the vagina opened. Copulatory plug was observed and vaginal smears were taken to guarantee successful mating. Thirty-eight embryos were collected between Days 3.5 and 4.5 after ovulation at the morula and early blastocyst stages. Five recipient females were synchronized by a daily 0.1-mL dose of altrenogest (Regumate® Equine, Intervet, France) per os by means of a syringe for 15 days. Two embryos were transferred into each uterine horn by laparotomy at Day 3.5 and 4.5 after ovulation. Two types of pipettes were tested for embryo transfer: pulled glass pipettes approximately 0.3 mm in diameter in 2 female recipients and plastic open pulled straws (OPS, Minitüb®, Germany) in 3 recipients. Pregnancy diagnosis was detected by observation of no return to oestrus at Day 16 and confirmed by ultrasonography. None of the 3 OPS-transferred females were pregnant. One of the 2 pulled glass pipette–transferred females was diagnosed as pregnant and delivered 2 stillbirths (one per uterine horn). There were no postsurgical complications and the females undergoing embryo transfer returned to normal reproduction. We demonstrated that a classic surgical embryo transfer method is possible under field conditions to obtain pregnancy in this species. We suggest further studies using glass pipettes, which allow a more precise embryo deposition. Future experiments will incorporate the transfer of frozen-thawed embryos on a larger scale.

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Influence of Litter Size at Birth on Productive Parameters in Guinea Pigs (Cavia porcellus)

Animals ◽

10.3390/ani10112059 ◽

2020 ◽

Vol 10 (11) ◽

pp. 2059

Author(s):

Angela Edith Guerrero Pincay ◽

Raúl Lorenzo González Marcillo ◽

Walter Efraín Castro Guamàn ◽

Nelson Rene Ortiz Naveda ◽

Deyvis Angel Grefa Reascos ◽

...

Keyword(s):

Guinea Pig ◽

Litter Size ◽

Guinea Pigs ◽

Growth And Development ◽

Meat Production ◽

Cavia Porcellus ◽

Mixed Feeding ◽

Balanced Diet ◽

Pig Meat ◽

Size At Birth

A study was conducted at the Escuela Superior Politècnica de Chimborazo, Ecuador, to evaluate the influence of litter size of guinea pigs (Cavia porcellus) on their development and to establish the economic profitability of the production system. Forty-eight animals were used, distributed into litters of two, three, and four rodents per litter, with a balanced diet and green fresh alfalfa for the weaning, growth, and fattening stage, the rodents and litters were randomly selected, applying the statistical model completely randomly and evaluating different variables across 120 days. The litters of three guinea pigs obtained the best productive responses and economic profitability. With respect to sex, the males presented better productive behavior, greater economic increase, and less cost, evidencing that mixed feeding influences the number of guinea pigs per birth in terms of growth and development. The results serve to improve guinea pig meat production for the rural population.

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Genomic Characterization of Campylobacter jejuni Adapted to the Guinea Pig (Cavia porcellus) Host

Frontiers in Cellular and Infection Microbiology ◽

10.3389/fcimb.2021.607747 ◽

2021 ◽

Vol 11 ◽

Author(s):

Craig T. Parker ◽

Kerry K. Cooper ◽

Francesca Schiaffino ◽

William G. Miller ◽

Steven Huynh ◽

...

Keyword(s):

Guinea Pig ◽

Campylobacter Jejuni ◽

Guinea Pigs ◽

Host Specialization ◽

Whole Genome Sequence ◽

Gene Gain ◽

Cavia Porcellus ◽

Middle Income ◽

Anatomy And Physiology ◽

Genes Encoding

Campylobacter jejuni is the leading bacterial cause of gastroenteritis worldwide with excessive incidence in low-and middle-income countries (LMIC). During a survey for C. jejuni from putative animal hosts in a town in the Peruvian Amazon, we were able to isolate and whole genome sequence two C. jejuni strains from domesticated guinea pigs (Cavia porcellus). The C. jejuni isolated from guinea pigs had a novel multilocus sequence type that shared some alleles with other C. jejuni collected from guinea pigs. Average nucleotide identity and phylogenetic analysis with a collection of C. jejuni subsp. jejuni and C. jejuni subsp. doylei suggest that the guinea pig isolates are distinct. Genomic comparisons demonstrated gene gain and loss that could be associated with guinea pig host specialization related to guinea pig diet, anatomy, and physiology including the deletion of genes involved with selenium metabolism, including genes encoding the selenocysteine insertion machinery and selenocysteine-containing proteins.

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Formamide denaturation of chromosomal DNA for in situ hybridization and C-band preparation in the guinea pig, Cavia porcellus

Experimental Cell Research ◽

10.1016/0014-4827(76)90054-9 ◽

1976 ◽

Vol 102 (2) ◽

pp. 385-393 ◽

Cited By ~ 8

Author(s):

H.R. Hubbell ◽

C.G. Sahasrabuddhe ◽

T.C. Hsu

Keyword(s):

In Situ Hybridization ◽

Guinea Pig ◽

Cavia Porcellus ◽

Chromosomal Dna

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Uterine blood flow and timing of blastocyst implantation in the guinea pig

AJP Endocrinology and Metabolism ◽

10.1152/ajpendo.1981.241.2.e142 ◽

1981 ◽

Vol 241 (2) ◽

pp. E142-E145

Author(s):

D. R. Garris ◽

D. S. Whitehead

Keyword(s):

Blood Flow ◽

Guinea Pig ◽

Guinea Pigs ◽

Temporal Relationship ◽

Oxygen Electrode ◽

Uterine Blood Flow ◽

Serum Estradiol ◽

Dramatic Rise ◽

Blastocyst Implantation

The temporal and direct relationships between serum estradiol (E) and progesterone (P) levels and uterine blood flow (UBF) and intrauterine oxygen tension (IU PO2) were examined in guinea pigs between days 1 and 8 of pregnancy. Both UBF and IU PO2 were measured in situ using a noninvasive electromagnetic blood flow monitor and needle oxygen electrode, respectively. Serum P levels remained relatively constant throughout the first 8 days of pregnancy. In contrast, serum E levels declined to basal levels between days 1 and 3, and then subsequently rose between days 4 and 7 before again falling to basal levels by day 8. The changes in UBF and IU PO2 paralleled those of serum E levels, both exhibiting a rise between days 5 and 6. The direct effect of oil, E, or P injections on UBF and IU PO2 measurements in ovariectomized animals indicated that E induced a dramatic rise in both uterine parameters, whereas both measurements remained at basal levels after oil or P treatment. The results of this study indicate that UBF and IU PO2 levels are directly regulated by the cyclic fluctuations in serum E. The temporal relationship between the days 4 to 7 rise in serum E, UBF, and IU PO2 levels and the timing of blastocyst implantation suggest that these events are involved in uterine preparation for nidation in the guinea pig.

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Antipredator behaviour of domestic guinea pigs (Cavia porcellus)

Acta Veterinaria Brno ◽

10.2754/avb201685030293 ◽

2016 ◽

Vol 85 (3) ◽

pp. 293-301 ◽

Cited By ~ 1

Author(s):

Aneta Baklová ◽

Eva Baranyiová ◽

Hana Šimánková

Keyword(s):

Guinea Pigs ◽

Antipredator Behaviour ◽

Cavia Porcellus ◽

Laboratory Setting ◽

Control Test ◽

Bird Of Prey ◽

Laboratory Conditions ◽

Males And Females ◽

And Control ◽

Wallis Anova

The objective of this study was to test the reactions of domestic guinea pigs to the presence of aerial and terrestrial predators in a laboratory setting. We measured the behavioural reactions of 27 adolescent guinea pigs to the presence of a dog, imitation of a bird of prey and an unknown human as control. Kruskal-Wallis ANOVA and Mann-Whitney U Test were used to analyse the differences in duration and frequency of responses (freezing, fleeing, and vigilance) to predators. When confronted with the dog, guinea pigs reacted for the longest time and most frequently by freezing. In presence of the bird of prey, they responded for the longest time and most often by freezing and fleeing. In presence of a human, they showed mostly vigilance. When comparing reactions to the dog and human, there were differences in duration and frequency of freezing and fleeing. When comparing reactions to the bird of prey and control test, we observed differences between fleeing and vigilance. The durations and frequencies of freezing, fleeing and vigilance to the dog and bird of prey were different. The only differences in reactions of males and females occurred in duration and frequency of fleeing in presence of the bird of prey. No vocalization was observed except for two occurrences, of a “drrr” and a “chirrup”. Our results indicate that domestic guinea pigs tested under laboratory conditions can discriminate between a terrestrial and an aerial predator, when exposed to them individually. Their antipredator behaviours remained functional, although their vocalizations may have been affected by the absence of signal receivers.

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