scholarly journals The impact of COVID-19 threats, and preventive chain of action: molecule to medicine

2021 ◽  
Vol 17 (3) ◽  
pp. 119-123
Author(s):  
Mohammed H. Alqahtani ◽  
Diane E. Heck ◽  
Hong Duck Kim
Keyword(s):  
Medical Application ◽  
Multidimensional Data ◽  
Individual Level ◽  
Decision Tools ◽  
Knowledge Based ◽  
Educational Engagement ◽  
Life Threatening ◽  
Novel Coronavirus ◽  
The Individual ◽  
The Impact

The emergence of the novel coronavirus (SARS-CoV-2) had affected us significantly from the individual level, to nationwide and global with a big loss of finances, and the freezing of various factories, schools, and transportation in communities The pandemic started with anxiety and a loss of health guidance and policies due to the unknown causes of viral transmission to human features as well as a high infection rate with low mortality It remains the original source of Covid-19 where it comes from and what is the reality of real viral entities and its origin such as natural born and recombinant viral variants in the case of COVID-19 pandemic. This sentence is unclear. In this short perspective article, we address some issues of risk assessment and management issues using molecular-based decision tools which may benefit or provide future drills to counteract health and clinic safety against a viral pandemic. Every pandemic gives us life threatening lessons on previous and disconnected human networks due to uncertainty of viral infection, which we learned from this COVID-19 pandemic case as well. It gives us some insight on how to rebuild our community regarding the strength of public health and the integration of science tools into the early phase of medical application, such as the role of molecular diagnostics through educational engagement. To promote the value of awareness with solid knowledge-based communication and to develop resilient preventive solutions for supply chains or prevention, the systematic practice of connectivity through visual format using multidimensional data outcomes could help reconsider the leverage of molecules as a bridge for the improvement and application of updated scientific tools of prediction precisely to identify unknown pathogens encompass rigor community-based activity likelihood sensitivity and resistance to pathogen infiltrated society in the future.

scholarly journals Harnessing testing strategies and public health measures to avert COVID-19 outbreaks during ocean cruises

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Gerardo Chowell ◽  
Sushma Dahal ◽  
Raquel Bono ◽  
Kenji Mizumoto
Keyword(s):  
Public Health ◽  
Cost Effective ◽  
Contact Network ◽  
Social Distancing ◽  
Individual Level ◽  
Health Measures ◽  
Testing Strategies ◽  
Novel Coronavirus ◽  
The Individual ◽  
The Impact

AbstractTo ensure the safe operation of schools, workplaces, nursing homes, and other businesses during COVID-19 pandemic there is an urgent need to develop cost-effective public health strategies. Here we focus on the cruise industry which was hit early by the COVID-19 pandemic, with more than 40 cruise ships reporting COVID-19 infections. We apply mathematical modeling to assess the impact of testing strategies together with social distancing protocols on the spread of the novel coronavirus during ocean cruises using an individual-level stochastic model of the transmission dynamics of COVID-19. We model the contact network, the potential importation of cases arising during shore excursions, the temporal course of infectivity at the individual level, the effects of social distancing strategies, different testing scenarios characterized by the test’s sensitivity profile, and testing frequency. Our findings indicate that PCR testing at embarkation and daily testing of all individuals aboard, together with increased social distancing and other public health measures, should allow for rapid detection and isolation of COVID-19 infections and dramatically reducing the probability of onboard COVID-19 community spread. In contrast, relying only on PCR testing at embarkation would not be sufficient to avert outbreaks, even when implementing substantial levels of social distancing measures.

scholarly journals Harnessing testing strategies and public health measures to avert COVID-19 outbreaks during ocean cruises

2021 ◽  
Author(s):  
Gerardo Chowell ◽  
Sushma Dahal ◽  
Raquel Bono ◽  
Kenji Mizumoto
Keyword(s):  
Public Health ◽  
Cost Effective ◽  
Contact Network ◽  
Social Distancing ◽  
Individual Level ◽  
Health Measures ◽  
Testing Strategies ◽  
Novel Coronavirus ◽  
The Individual ◽  
The Impact

AbstractTo ensure the safe operation of schools, workplaces, nursing homes, and other businesses during COVID-19 pandemic there is an urgent need to develop cost-effective public health strategies. Here we focus on the cruise industry which was hit early by the COVID-19 pandemic, with more than 40 cruise ships reporting COVID-19 infections. We apply mathematical modeling to assess the impact of testing strategies together with social distancing protocols on the spread of the novel coronavirus during ocean cruises using an individual-level stochastic model of the transmission dynamics of COVID-19. We model the contact network, the potential importation of cases arising during shore excursions, the temporal course of infectivity at the individual level, the effects of social distancing strategies, different testing scenarios characterized by the test’s sensitivity profile, and the testing frequency. Our findings indicate that PCR testing at embarkation and daily testing of all individuals aboard, together with increased social distancing and other public health measures, should allow for rapid detection and isolation of COVID-19 infections and dramatically reducing the probability of onboard COVID-19 community spread. In contrast, relying only on PCR testing at embarkation would not be sufficient to avert outbreaks, even when implementing substantial levels of social distancing measures.

scholarly journals Natural History of NAFLD

2021 ◽  
Vol 10 (6) ◽  
pp. 1161
Author(s):  
Raluca Pais ◽  
Thomas Maurel
Keyword(s):  
Liver Disease ◽  
Natural History ◽  
Disease Progression ◽  
Specific Treatment ◽  
Alcoholic Fatty Liver ◽  
Individual Level ◽  
Close Relationship ◽  
History Of ◽  
The Individual ◽  
The Impact

The epidemiology and the current burden of chronic liver disease are changing globally, with non-alcoholic fatty liver disease (NAFLD) becoming the most frequent cause of liver disease in close relationship with the global epidemics of obesity, type 2 diabetes and metabolic syndrome. The clinical phenotypes of NAFLD are very heterogeneous in relationship with multiple pathways involved in the disease progression. In the absence of a specific treatment for non-alcoholic steatohepatitis (NASH), it is important to understand the natural history of the disease, to identify and to optimize the control of factors that are involved in disease progression. In this paper we propose a critical analysis of factors that are involved in the progression of the liver damage and the occurrence of extra-hepatic complications (cardiovascular diseases, extra hepatic cancer) in patients with NAFLD. We also briefly discuss the impact of the heterogeneity of the clinical phenotype of NAFLD on the clinical practice globally and at the individual level.

The Evolution of the Role of U.S. School Nurses in Adolescent Mental Health at the Individual, Community, and Systems Level: An Integrative Review

2022 ◽  
pp. 105984052110681
Author(s):  
Ashwini R. Hoskote ◽  
Emily Croce ◽  
Karen E. Johnson
Keyword(s):  
Mental Health ◽  
Adolescent Mental Health ◽  
School Nurse ◽  
School Nurses ◽  
Integrative Review ◽  
School Nursing ◽  
Individual Level ◽  
The Individual ◽  
The Impact

School nurses are crucial to addressing adolescent mental health, yet evidence concerning their evolving role has not been synthesized to understand interventions across levels of practice (i.e., individual, community, systems). We conducted an integrative review of school nurse roles in mental health in the U.S. related to depressive symptoms, anxiety, and stress. Only 18 articles were identified, published from 1970 to 2019, and primarily described school nurses practicing interventions at the individual level, yet it was unclear whether they were always evidence-based. Although mental health concerns have increased over the years, the dearth of rigorous studies made it difficult to determine the impact of school nurse interventions on student mental health outcomes and school nurses continue to feel unprepared and under supported in this area. More research is needed to establish best practices and systems to support school nursing practice in addressing mental health at all levels of practice.

The consequences of social intolerance on non-violent protest

2015 ◽  
Vol 8 (4) ◽  
pp. 567-588 ◽  
Author(s):  
Carolin Rapp ◽  
Kathrin Ackermann
Keyword(s):  
Social Psychology ◽  
Rational Choice ◽  
Ecological Effect ◽  
Multilevel Analyses ◽  
Cultural Groups ◽  
Individual Level ◽  
The Individual ◽  
Established Democracies ◽  
The Impact ◽  
Positive Effect

This paper scrutinizes the impact of intolerance toward diverse ethnic, religious, and cultural groups on an individual’s willingness to actively engage in non-violent protest. Following new insights, we examine the individual as well as the ecological effect of social intolerance on protest behavior. Drawing from insights of social psychology and communication science, we expect that the prevalence of intolerance reinforces the positive effect of individual-level intolerance on protest participation. From a rational choice perspective, however, a negative moderating effect is expected, as the expression of opinions becomes redundant for intolerant individuals in an intolerant society. We base our multilevel analyses on data from theWorld Values Surveyscovering 32 established democracies. Our results reveal that intolerance leads to more non-violent protest participation. This relationship, however, is strongly influenced by the prevalence of intolerance in a country.

scholarly journals The Impact of Customer Contact on Collective Human Energy in Firms

2018 ◽  
Vol 44 (5) ◽  
pp. 915-952
Author(s):  
Petra Kipfelsberger ◽  
Heike Bruch ◽  
Dennis Herhausen
Keyword(s):  
Transformational Leadership ◽  
Organizational Level ◽  
Data Set ◽  
Customer Contact ◽  
Individual Level ◽  
Moderated Mediation Model ◽  
Human Energy ◽  
The Individual ◽  
High Level ◽  
The Impact

This article investigates how and when a firm’s level of customer contact influences the collective organizational energy. For this purpose, we bridge the literature on collective human energy at work with the job impact framework and organizational sensemaking processes and argue that a firm’s level of customer contact is positively linked to the collective organizational energy because a high level of customer contact might make the experience of prosocial impact across the firm more likely. However, as prior research at the individual level has indicated that customers could also deplete employees’ energy, we introduce transformational leadership climate as a novel contingency factor for this linkage at the organizational level. We propose that a medium to high transformational leadership climate is necessary to derive positive meaning from customer contact, whereas firms with a low transformational leadership climate do not get energized by customer contact. We tested the proposed moderated mediation model with multilevel modeling and a multisource data set comprising 9,094 employees and 75 key informants in 75 firms. The results support our hypotheses and offer important theoretical contributions for research on collective human energy in organizations and its interplay with customers.

Management of Neurological Emergencies in Children: An Updated Overview

2021 ◽  
Author(s):  
Mario Mastrangelo ◽  
Valentina Baglioni
Keyword(s):  
Motor Impairment ◽  
Febrile Seizures ◽  
Diagnostic Tools ◽  
Emergency Setting ◽  
Neurological Emergencies ◽  
Life Threatening ◽  
Novel Coronavirus ◽  
A Minor ◽  
The Impact

AbstractNeurological emergencies account for about one-third of the highest severity codes attributed in emergency pediatric departments. About 75% of children with acute neurological symptoms presents with seizures, headache, or other paroxysmal events. Life-threatening conditions involve a minor proportion of patients (e.g., less than 15% of children with headache and less than 5% of children with febrile seizures). This review highlights updated insights about clinical features, diagnostic workup, and therapeutic management of pediatric neurological emergencies. Particularly, details will be provided about the most recent insights about headache, febrile seizures, status epilepticus, altered levels of consciousness, acute motor impairment, acute movement disorders, and functional disorders, as well as the role of diagnostic tools (e.g., neuroimaging, lumbar puncture, and electroencephalography), in the emergency setting. Moreover, the impact of the current novel coronavirus disease2019 (COVID-19) pandemic on the evaluation of pediatric neurologic emergencies will also be analyzed.

Trust, Ethnicity and Integrity in East Africa: Experimental Evidence from Kenya and Tanzania

2017 ◽  
Vol 2 (1) ◽  
pp. 88-123 ◽  
Author(s):  
Dominic Burbidge ◽  
Nic Cheeseman
Keyword(s):  
Ethnic Diversity ◽  
Negative Impact ◽  
Common Knowledge ◽  
Individual Level ◽  
Trust Games ◽  
Negative Effect ◽  
Experimental Games ◽  
The Individual ◽  
The Impact ◽  
First Time

AbstractPolitical economy comparisons of Kenya and Tanzania have often found the political salience of ethnicity to be far higher in the former than the latter, with a negative impact on intercommunal trust. This difference has tended to be explained on the basis of the different kinds of leadership that the two countries experienced after independence. However, these findings have typically been demonstrated using aggregate or survey data. This paper assesses the salience of ethnicity at the individual level for the first time, deploying monetized two-round trust games in urban Kenya and Tanzania. The experimental games isolate the comparative impact of common knowledge of ethnicity and integrity among a quasi-random selection of 486 citizens. Verifying previous findings, we observe higher levels of trust and trustworthiness in Tanzania as compared with Kenya. Further, in comparison with Kenya, any shared knowledge of ethnic identities in Tanzania leads players to transfer fewer resources, while common knowledge that both players are “honest” led to higher transfers there than in Kenya. These results provide robust evidence of higher levels of trust in Tanzania, and of the negative effect in that country of common knowledge of ethnicity on levels of cooperation. The findings demonstrate the way in which political context can shape the impact of ethnic diversity, and encourage further experimental research that looks at the intersubjective dynamics of social cooperation.

Interesting Knowledge Patterns in Databases

2011 ◽  
pp. 297-304
Author(s):  
Rajesh Natarajan ◽  
B. Shekar
Keyword(s):  
Knowledge Creation ◽  
Explicit Knowledge ◽  
Business Environment ◽  
Knowledge Discovery In Databases ◽  
Individual Level ◽  
Knowledge Based ◽  
Transactional Databases ◽  
Rich Information ◽  
The Individual ◽  
Combination Mode

Knowledge management (KM) transforms a firm’s knowledge-based resources into a source of competitive advantage. Knowledge creation, a KM process, deals with the conversion of tacit knowledge to explicit knowledge and moving knowledge from the individual level to the group, organizational, and interorganizational levels (Alavi & Leidner, 2001). Four modes¾namely, socialization, externalization, combination, and internalization¾create knowledge through the interaction and interplay between tacit and explicit knowledge. The “combination” mode consists of combining or reconfiguring disparate bodies of existing explicit knowledge (like documents) that lead to the production of new explicit knowledge (Choo, 1998). Transactional databases are a source of rich information about a firm’s processes and its business environment. Knowledge Discovery in Databases (KDD), or data mining, aims at uncovering trends and patterns that would otherwise remain buried in a firm’s operational databases. KDD is “the non-trivial process of identifying valid, novel, potentially useful, and ultimately understandable patterns in data.” (Fayyad, Piatetsky-Shapiro, & Smyth, 1996). KDD is a typical example of IT-enabled combination mode of knowledge creation (Alavi & Leidner, 2001).

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