scholarly journals Active search about latex in injectable drugs for patient’s safety in medical therapy

Author(s):  
Roberta G. PEIXE ◽  
Maria C. SODRÉ ◽  
Beatriz B. OLIVEIRA ◽  
Luana P. GONÇALVES ◽  
Ian G. HALM ◽  
...  

Objectives: To classify injectable drugs used in a general hospital inventory according to latex presence or absence in vials with rubber stoppers, antibiotics, and electrolytes bags. Methods: The information about latex content has been collected from medicine industries, after identification of authorized manufacturers in Brazil, through the National Health Surveillance Agency (ANVISA) medicine search database. Medicines have been grouped per pharmaceutical manufacturers, and data were collected through telephone or e-mail. Only written information from pharmaceutical companies were considered. Results: Among 161 medicines used in the hospital packaged in vials with rubber stoppers, antibiotics, and electrolytes bags, 123 (76.4%) medicine-related responses were received, covering 540 (82.2%) different presentations. For this, from 87 contacts, 70 (80.5%) companies responded and 65 (74.7%) provided information related to the presence or absence of the allergen. Among the medicine list, 8 (6.5%) were identified as containing latex (in 12 different presentations – 2.2%) and 101 medications (82.1%) in 507 presentations (93.9%) do not contain latex. The manufacturers responded that the medicine was latex-free, but could not confirm for raw materials (6 medicines – 4.9% - in 6 different presentations – 1.1%) and that they were unable to ensure there was no contact with latex during manipulation (4 medicines – 3.3% - in 8 different presentations – 1.5%). For 4 medicines (3.3%) in 7 different presentations (1.3%), the companies were inconclusive, as they could not confirm whether they were latex-free or not. Conclusion: Although latex is a known allergen, information about the presence of latex components in pharmaceutical packaging and package inserts needs improvement, since the active search identified 161 medicines packaged in vials with rubber stoppers, antibiotics, and electrolytes bags that failed to depict this information. The results of this survey endorse the Importance of displaying this information on medicines label or packaging in order to ensure healthcare professionals easy access and prompt consultation.

2008 ◽  
Vol 59 (2) ◽  
pp. 129-134
Author(s):  
Ion Teoreanu ◽  
Roxana Lucia Dumitrache ◽  
Stefania Stoleriu

Any change of the raw material sources for glazes, economically, ecologically motivated, and also from the glaze quality point of view, is conditioned by the molecular formula rationalization and by the variation limits of the molecular formula, respectively. The proper glaze compositions are placed within their limit variation intervals with optimized processing and utilization properties. For this purpose, the rationalization criteria and procedures of molecular formulas are summarized in the present paper, as well as the results referring to their rationalization obtained in the authors� previous work. Thus, one starts from a base of raw materials that are selected, usable and also accessible for the design and producing of the glazes. On these bases the groundwork and the design equation for the glaze recipes are developed, exemplified for a single glaze. For an easy access to results, computer programs are used for an easy access to results.


Author(s):  
L.E. Yasinskaya ◽  

Introduction. Earlier, the comparative analysis of the commercial and investment activities of the companies that play the key roles in the investment processes in the Russian pharmaceutical industry and operate within the four main business models (biotechnological, generic, specialized pharmaceutical companies, active pharmaceutical ingredient (API) manufacturers) has been conducted. No full assessment of the companies’ activitiesis conceivable without a financial analysis of their activities to identify the risks of investment activities. Objective of the study. A detailed comparative analysis of the financial standing of domestic pharmaceutical manufacturers operating within the selected business models for further identification of potential financial risks for investors. Research procedure and article structure. Analysis of RAS statements (forms 1 and 2) of 72 over 500 million revenue companies grouped together as selected business models for the period from 2015 to 2019. Results. The researchers provided a detailed description of the commercial activities of domestic pharmaceutical companies within the business models under consideration. The companies within various business models showed positive revenue growth rates over the past five years. All business models demonstrate consistently high business profitability and a significant share of own capital in the asset profile. Conclusion. The results of the study show the stable financial standing of the pharmaceutical companies within various business models. The biotechnology sector companies that are the most attractive for investments have the highest quality financial standing. The specialized and generic companies show similar consistently strong performance. API manufacturers that the companies with relatively small revenues are actively developing and are attractive to restrained budget investors.


2019 ◽  
Vol 2 (2) ◽  
pp. 188
Author(s):  
Dilla Cattleyana ◽  
Adytira Rachman

Micro, Small and Medium Enterprises (UMKM) has an important role in the Indonesian economy, one of which can help the per capita income of the Indonesian state, especially in Banyuwangi Regency, as well as in the UM Banana Sale UD UD. Sumber Alam Buana, located at the eastern end of the island of Java, precisely in Banyuwangi. The UMKM is one of Banyuwangi's original typical food businesses from Ambon banana raw material, bearing in mind that typical food is identical to souvenirs (souvenirs) when visiting Banyuwangi, certainly not forgetting to bring and share them with you. However, there are problems in the field of production of UD Banana Banana UD, namely the low production capacity of processing banana raw materials because it still uses a cutting knife and the appropriate method has not been applied to record raw materials or finished goods so that the owner is less able to control the cycle of raw materials or finished goods. While in the marketing sector it is still conventional to be entrusted in a gift shop so that it can only wait for whether the product is sold or vice versa. The solution to the development activities of UMKM Sale Banana UD Sumber Alam Buana includes counseling and training using a banana chopper tool that is more efficient than a knife that has been used to chop banana raw materials. Whereas in terms of recording to help partners to control raw material inventory and finished goods efficiently and effectively, the need for training knowledge and assistance to owners and employees using a perpetual method stock card (inventory). To expand market share that has demanded the use of technology, training is held to make e-mail as a portal to access several e-commerce websites and to open online stores through social media such as Facebook and others. The results achieved in the Community Service program are the development of this business in terms of increasing production capacity, managing raw materials, expanding markets and increasing income.


2021 ◽  
Vol 1 (1) ◽  
pp. 34-49
Author(s):  
Ruby T. Nguyen ◽  
◽  
Ange-Lionel Toba ◽  
Michael H. Severson ◽  
Ethan M. Woodbury ◽  
...  

<abstract> <p>Material databases are important tools to provide and store information from material research. Rising concerns about supply-chain risks to raw materials presents a need to incorporate raw-material market and end-use application data, beyond basic chemical and physical properties, into a material database. One key challenge for researchers working on critical materials is information scarcity and inconsistency. This paper introduces, as a result of a two-year project, a critical-material commodity database (CMCD) incorporated with a low-code web-based platform that allows easy access for users and simple updates for the authors. The main goal of this project was to educate material scientists on the applications having the most impact on the supply chain and current industrial specifications/markets for each application. The objective was to provide material researchers with harmonized information so that they could gain a better understanding of the market, focus their technologies on an application with a high potential for commercialization, and better contribute to supply-chain risk reduction. While the goal was met with high receptivity, several limitations stemmed from query design, distribution platform, and quality of data source. To overcome some of these limitations and expand on CMCD's potential, we are building a public webpage with an improved interface, better data organization, and higher extensibility.</p> </abstract>


STORIA URBANA ◽  
2009 ◽  
pp. 83-100
Author(s):  
Manuel Vaquero Pineiro

- The different forms of presence of Spanish merchants in Rome since the beginning of Early Modern Age: ideas for a debate at European level. Between the 15th and the 16th centuries, due also to the political coverage offered by the empire of Charles V, both Castilians and Catalans succeeded in establishing themselves as the most dynamic merchants in Europe. The control they had over strategic raw materials such as wool, iron and alum and their privileged position gave them easy access to monetary flows in the coastal cities from Flanders to the Mediterranean, where a number Spanish colonies were established. These cities were soon granted with major privileges by local authorities, which fostered the settling of merchants and bankers in certain areas therein. The result, as in the case of Bruges, was the creation of districts protected by exclusive jurisdictional rights or, as in the case of Rome, a random scattering of the new settlers, with no real reference points. In the mid 16th century, in Rome the distribution of places of work and residence followed no national or religious criteria. The complex structure of social relations was thus reflected also in Rome topography.


Author(s):  
Tatiane da Silva Dal Pizzol ◽  
Cassia Garcia Moraes ◽  
Paulo Sérgio Dourado Arrais ◽  
Andréa Dâmaso Bertoldi ◽  
Luiz Roberto Ramos ◽  
...  

ABSTRACT: Introduction: The written information on medicines has been acknowledged as an important tool for health education. Objective: To analyze the use and understanding of medicine package inserts by users and assess sociodemographic and medical factors associated with their comprehension. Method: Data in this analysis are part of the PNAUM National Survey - a cross-sectional population-based study conducted in Brazil. Descriptive statistics and the Pearson χ2 tests were performed to compare proportions between sociodemographic and medical characteristics, as well as use and understanding of medicine package inserts. Results: A total of 28.427 individuals responded to questions related to medicine package inserts. From these, 59.6% (95%CI 57.7 - 61.5) said they usually read the inserts, and 98.4% (95%CI 98.0 - 98.8) considered them necessary. Among people who read the medicine package inserts, more than half indicated difficulties with legibility (57.4%; 95%CI 55,2 - 59,6) and readability (54.1%; 95%CI 52.1 - 56.1). People from a lower education level reported greater difficulty in understanding them. Conclusion: The larger portion of the population usually read medicine package inserts. Nevertheless, people have difficulty in reading and understanding them.


2002 ◽  
Vol 35 (1) ◽  
pp. 127-149 ◽  
Author(s):  
David Romano

This article examines the effect of modern media and communications technology on ethnic nationalist resurgence, using the Kurds as a case example. Television, satellite communications, the Internet and easy access to publishing technology now facilitate ethnic nationalist challenges to state hegemony and monopoly of information. Additionally, modern media and communications technology can turn a humiliating defeat into a catalyst for a more unified, stronger, ethnic nationalist movement. Globally broadcast images of such a defeat arouse the passions and indignation of even those people who only nominally identify themselves with the ethnic group in question. At the same time, communications technology such as telephones, faxes and e-mail facilitate the channeling of such indignation into immediate group protest and action which, in turn, strengthens the ethnic identification of action participants.


2011 ◽  
Vol 56 (01) ◽  
pp. 1-18 ◽  
Author(s):  
JOERGEN OERSTROEM MOELLER

For 200 years, we have lived with capitalism in its American style forged easy access to raw materials. Despite entering an era of scarcities, economics is still anchored in growth and distribution theories reflecting the world of plenty. Production theory does not recognize the significance of sharing of knowledge and group behavior introduced by ICT. Consumption theory is still about buying 'more', neglecting the element of uncertainty. Competition has been eradicated and replaced by a limited number of gigantic corporations. Only recently has economics started to go interdisciplinary to incorporate psychology and brain research to explain behavior when confronted with economic choices and the difference between individual and group behavior.


2016 ◽  
Vol 14 (1) ◽  
pp. 52-55
Author(s):  
Talita Muniz Maloni Miranda ◽  
Andressa de Abreu Ferraresi

ABSTRACT Objective Standardization and systematization of data to provide quick access to compatibility of leading injectable drugs used in hospitals for parenteral nutrition. Methods We selected 55 injectable drugs analyzed individually with two types of parenteral nutrition: 2-in-1 and 3-in-1. The following variables were considered: active ingredient, compatibility of drugs with the parenteral nutrition with or without lipids, and maximum drug concentration after dilution for the drugs compatible with parenteral nutrition. Drugs were classified as compatible, incompatible and untested. Results After analysis, relevant information to the product’s compatibility with parental nutrition was summarized in a table. Conclusion Systematization of compatibility data provided quick and easy access, and enabled standardizing pharmacists work.


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