scholarly journals Variations of Vitamin D in Various Stages of Breast Carcinoma: A Randomized Case Control Study

2021 ◽  
pp. 11-14
Author(s):  
Aananda Krishna KS ◽  
Saai Ram Thejas ◽  
Aniruddhan VJ ◽  
Sudarsan Adithya
Keyword(s):  
Vitamin D ◽  
Breast Carcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Dietary and serum vitamin D and preeclampsia risk in Chinese pregnant women: a matched case–control study

2021 ◽  
pp. 1-26
Author(s):  
Xue-min Huang ◽  
Yan-hua Liu ◽  
Han Zhang ◽  
Yuan Cao ◽  
Wei-feng Dou ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dietary Intake ◽  
Pregnant Women ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Concentrations ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

Abstract The effect of vitamin D (VD) on the risk of preeclampsia (PE) is uncertain. Few of previous studies focused on the relationship between dietary VD intake and PE risk. Therefore, we conducted this 1:1 matched case-control study to explore the association of dietary VD intake and serum VD concentrations with PE risk in Chinese pregnant women. A total of 440 pairs of participants were recruited during March 2016 to June 2019. Dietary information was obtained using a 78-item semi-quantitative food frequency questionnaire. Serum concentrations of 25(OH)D2 and 25(OH)D3 were measured by liquid chromatography–tandem mass spectrometry. Multivariate conditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Restricted cubic splines (RCS) were plotted to evaluate the dose-response relationship of dietary VD intake and serum VD concentrations with PE risk. Compared with the lowest quartile, the ORs of the highest quartile were 0.45 (95%CI: 0.29-0.71, Ptrend = 0.001) for VD dietary intake and 0.26 (95%CI: 0.11-0.60, Ptrend = 0.003) for serum levels after adjusting for confounders. In addition, the RCS analysis suggested a reverse J-shaped relationship between dietary VD intake and PE risk (P-nonlinearity = 0.02). A similar association was also found between serum concentrations of total 25(OH)D and PE risk (P-nonlinearity = 0.02). In conclusion, this study provides evidence that higher dietary intake and serum levels of VD are associated with the lower risk of PE in Chinese pregnant women.

scholarly journals Vitamin D Status and Its Role in First-Time and Recurrent Urinary Tract Infections in Children: A Case-Control Study

Children ◽  
2021 ◽  
Vol 8 (5) ◽  
pp. 419
Author(s):  
Carmen Muntean ◽  
Maria Săsăran
Keyword(s):  
Vitamin D ◽  
Urinary Tract ◽  
Case Control Study ◽  
Case Control ◽  
Study Group ◽  
Recurrent Utis ◽  
Vitamin D Levels ◽  
Tract Infections ◽  
First Time ◽  
Control Study

Vitamin D has emerged as a key factor in innate immunity. Its involvement in the pathogenesis of urinary tract infections (UTIs) has gained a lot of attention recently. The objective of this study is to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) levels and first-time or recurrent UTIs in children. A prospective, case-control study was conducted on 101 pediatric patients, who were divided into two groups: 59 patients with UTIs and 42 age-matched healthy controls. Serum 25(OH)D was determined in each child and expressed in ng/mL. Vitamin D presented significantly lower values in study group subjects than in healthy controls (p < 0.01). Moreover, a significantly higher prevalence of vitamin D insufficiency and deficiency was found in children with UTIs (p < 0.01). Patients with recurrent UTIs presented significantly lower levels of vitamin D than those with first-time UTIs (p = 0.04). Urinary tract abnormalities did not seem to exercise an additional effect upon vitamin D levels within the study group. In conclusion, first-time and recurrent UTIs are associated with lower vitamin D levels. Further studies are necessary to validate our findings, as well as future longitudinal research regarding efficacy of vitamin D supplementation in children with UTIs.

scholarly journals Vitamin D Levels in Patients with and without Acne and Its Relation to Acne Severity: A Case-Control Study

2020 ◽  
Vol Volume 13 ◽  
pp. 759-765
Author(s):  
Ghadah Alhetheli ◽  
Ahmed Ibrahim Abd Elneam ◽  
Adel Alsenaid ◽  
Mohammed Al-Dhubaibi
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Case Control ◽  
Vitamin D Levels ◽  
Control Study

Dose–response association between vitamin D deficiency and atopic dermatitis in children, and effect modification by gender: a case-control study

2019 ◽  
pp. 1-6
Author(s):  
Amal Ahmed Mohamed ◽  
Eman Mohamed Salah Ahmed ◽  
Youssef M. K. Farag ◽  
Nermeen Ibrahim Bedair ◽  
Nourelhuda Ahmed Nassar ◽  
...  
Keyword(s):  
Vitamin D ◽  
Atopic Dermatitis ◽  
Vitamin D Deficiency ◽  
Dose Response ◽  
Case Control Study ◽  
Case Control ◽  
Effect Modification ◽  
Control Study

scholarly journals Vitamin D status and breast cancer in Saudi Arabian women: case-control study

2013 ◽  
Vol 98 (1) ◽  
pp. 105-110 ◽  
Author(s):  
Fatimah M Yousef ◽  
Elizabeth T Jacobs ◽  
Paul T Kang ◽  
Iman A Hakim ◽  
Scott Going ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Case Control Study ◽  
Saudi Arabian ◽  
Case Control ◽  
Vitamin D Status ◽  
Control Study

Lower Vitamin D Level as a Risk Factor for Late Onset Neonatal Sepsis: An Observational Case–Control Study

2021 ◽  
Author(s):  
Shaimaa Reda Abdelmaksoud ◽  
Mostafa Abdel-Azim Mostafa ◽  
Rana Atef khashaba ◽  
Effat Assar
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Late Onset ◽  
Case Control ◽  
Sepsis Group ◽  
Term Neonates ◽  
Maternal Vitamin ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D ◽  
Control Study

Objective The aim of the study is to investigate the relation of neonatal and maternal vitamin D and late-onset sepsis (LOS) Study Design One-hundred twenty term neonates along with their mothers were enrolled in this case–control study. Sixty neonates who were admitted in the neonatal intensive care unit by LOS and had not been previously admitted for last 48 hours and did not receive antibiotics or vitamin D were enrolled as cases (sepsis) group. On the other hand, 60 healthy term neonates were referred as control group. Maternal and neonatal serum 25-OH vitamin D levels were assessed in both the cohorts. Results Maternal and neonatal 25-OH vitamin D levels in cases (17.2 and 16.1 ng/mL, respectively) were significantly lower than in controls (22.7 and 21 ng/mL, respectively) p = 0.001. In the study group, the neonatal 25-OH vitamin D was negatively correlated with C-reactive protein and length of hospital stay (r = −0.616 and −0.596, respectively) p <0.001 for both. With a cut-off value of 12.9 ng/mL, the specificity and positive predictive value of neonatal vitamin D were 83.3 and 74.4%, respectively. The odds ratio was 1.088 (95% CI = 1.034–1.144)) for LOS in vitamin D-deficient neonates. Conclusion Neonates with higher vitamin D level are at lower risk of LOS than those with vitamin D deficiency. Maternal vitamin D correlates with neonatal vitamin D. These data suggest that maternal vitamin supplementation during pregnancy may lower the risk of LOS. Key Points

Vitamin D intake during the first 4 years and onset of asthma by age 5: A nested case-control study

2017 ◽  
Vol 28 (7) ◽  
pp. 641-648 ◽  
Author(s):  
Bright I. Nwaru ◽  
Kishor Hadkhale ◽  
Niina Hämäläinen ◽  
Hanna-Mari Takkinen ◽  
Suvi Ahonen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Case Control ◽  
Vitamin D Intake ◽  
Nested Case Control ◽  
Control Study
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