Acute gastroenteritis with a new coronavirus infection in Novosibirsk residents

The aim of the study was to determine the frequency and clinical and laboratory features of acute gastroenteritis (OGE) in adult residents of Novosibirsk hospitalized with a new coronavirus infection (COVID-19) in 2020.Materials and methods. We examined 3581 patients aged 18 to 96 years with a diagnosis of “New coronavirus infection”, confirmed by the detection of SARS-CoV-2 RNA in the mucus from the oropharynx by PCR, hospitalized in the State Medical Institution NSO GICB No. 1 in 2020. Along with the generally accepted diagnostic methods, feces were examined by PCR in 50 patients with gastrointestinal syndrome to detect SARS-CoV-2 RNA using a set of original specific primers.Results. Of the 3,581 hospitalized adult patients with COVID-19, 74% of cases were diagnosed with bilateral polysegmental pneumonia, and 26% of cases were diagnosed with acute respiratory infection. Manifestations of OGE were observed in 6.8% (n=243) of patients. In the group of 50 COVID-19 patients, in whom the disease began with symptoms of OGE, it came to the fore in the clinical picture of the disease in 20% of cases, and SARS-Co- V2 RNA in the feces was detected in 62% of patients.Conclusion The established frequency of OGE in COVID-19 in adults shows the need to develop and implement in clinical practice test systems (PCR of SARS-CoV-2 RNA in feces) for the diagnosis of the intestinal form of a new coronavirus infection.

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Acute respiratory infection due to Mycoplasma pneumoniae: current status of diagnostic methods

European Journal of Clinical Microbiology & Infectious Diseases ◽

10.1007/s10096-010-0975-2 ◽

2010 ◽

Vol 29 (9) ◽

pp. 1055-1069 ◽

Cited By ~ 59

Author(s):

K. Loens ◽

H. Goossens ◽

M. Ieven

Keyword(s):

Mycoplasma Pneumoniae ◽

Respiratory Infection ◽

Acute Respiratory Infection ◽

Diagnostic Methods ◽

Current Status

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Clinical manifestations of new coronavirus infection (COVID-19) in children admitted to hospital

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) ◽

10.21508/1027-4065-2021-66-5-88-96 ◽

2021 ◽

Vol 66 (5) ◽

pp. 88-96

Author(s):

D. I. Sadykova ◽

S. V. Khaliullina ◽

V. A. Anokhin ◽

A. I. Ziatdinov ◽

S. A. Senek ◽

...

Keyword(s):

Risk Factors ◽

Viral Infection ◽

Clinical Picture ◽

Clinical Manifestations ◽

Infection Risk ◽

Hospitalized Children ◽

Respiratory Viral Infection ◽

Laboratory Features ◽

Infection Risk Factors ◽

Coronavirus Infection

Objective. To describe clinical and laboratory features of COVID-19 in children admitted to the hospital.Children characteristics and research methods. The authors carried out a retrospective observational study, which included 204 children admitted to the Kazan hospital with a diagnosis of “new coronavirus infection” in the period from May 1 to October 30, 2020.Results. It was revealed that all hospitalized children had RNA of the SARS-CoV-2 virus (100%) in a smear from the nasopharynx and oropharynx detected by PCR and only 50% of patients were diagnosed with lung tissue lesions by computed tomography. The clinical picture of COVID-19 in children most often corresponds to the classic manifestations of a respiratory viral infection. Risk factors for the development of severe forms, described in adults, were recorded only in isolated cases in our study.Conclusion. The clinical picture of COVID-19 in children most often corresponds to the classic manifestations of a respiratory viral infection. Risk factors for the development of severe forms, described in adults, were recorded in isolated cases in our study.

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Acute ischemia of the lower limb in a patient with infective endocarditis under the mask of coronavirus infection

Grekov s Bulletin of Surgery ◽

10.24884/0042-4625-2021-180-4-95-98 ◽

2021 ◽

Vol 180 (4) ◽

pp. 95-98

Author(s):

I. P. Mikhaylov ◽

V. A. Arustamyan ◽

B. V. Kozlovskij ◽

E. V. Kungurcev

Keyword(s):

Clinical Practice ◽

Infective Endocarditis ◽

Lower Extremity ◽

Successful Treatment ◽

Clinical Picture ◽

Lower Limb ◽

Clinical Case ◽

Acute Ischemia ◽

Coronavirus Infection

Despite the fact that significant success has been achieved in the treatment of patients with infective endocarditis (IE), difficulties in clinical practice arise in the diagnosis of this disease. The article analyzes a clinical case of successful treatment of a patient with acute ischemia of the lower extremity due to thromboembolic syndrome in IE, the diagnosis of which was initially regarded as COVID-19. The clinical case occurred during the coronavirus infection (COVID-19) pandemic, and all patients who initially complained of fever were regarded as potentially infected, which, with insufficient examination, masked the clinical picture of infective endocarditis.

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Acute Respiratory Infection Due to Chlamydia pneumoniae: Current Status of Diagnostic Methods

Clinical Infectious Diseases ◽

10.1086/511076 ◽

2007 ◽

Vol 44 (4) ◽

pp. 568-576 ◽

Cited By ~ 106

Author(s):

E. J. C. Goldstein ◽

S. Kumar ◽

M. R. Hammerschlag

Keyword(s):

Respiratory Infection ◽

Acute Respiratory Infection ◽

Chlamydia Pneumoniae ◽

Diagnostic Methods ◽

Current Status

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Frequency of Coronavirus NL63 Infection in Children with Upper Respiratory Infection by Real-Time PCR

Iranian Journal of Pediatrics ◽

10.5812/ijp.101905 ◽

2020 ◽

Vol 30 (3) ◽

Author(s):

Mahtab Mohammadi ◽

Seyed Ali Mohammad Arabzadeh ◽

Hamid Reza Mollaei ◽

Seyed Hamidreza Monavari ◽

Najmeh Nikpour

Keyword(s):

Real Time ◽

Respiratory Infection ◽

Real Time Pcr ◽

Acute Respiratory Infection ◽

Clinical Symptoms ◽

Upper Respiratory Infection ◽

Highly Sensitive ◽

Coronavirus Infection ◽

Upper Respiratory ◽

First Time

Background: Human coronavirus NL63 (HCoV-NL63) is a new respiratory virus associated with acute respiratory infection in children. Infection with this virus is usually accompanied by upper and lower infections of the respiratory tract in adults. Objectives: In a retrospective study, we investigated the incidence of coronavirus infection in children under the age of five years. Methods: We collected 138 specimens (nasal and throat swabs) from children less than five-years-old with acute respiratory infection from October 2018 to December 2019. Then, HCoV-NL63 was investigated using real-time PCR. Results: Out of 138 samples, 33 (23.9%) were positive for coronavirus NL63, including 21 (63.6%) male samples and 12 (36.4%) female samples. There was no significant correlation between gender and positivity for coronavirus infection (P > 0.05). However, the association of clinical symptoms with the virus was statistically significant (P < 0.05). Conclusions: This study was conducted for the first time in Kerman Province. In this study, the frequency of coronavirus NL63 was evaluated among children with acute respiratory infection with a highly sensitive method, real-time PCR. The prevalence of this virus was 33%, which was more frequent than in similar studies.

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