scholarly journals Perubahan tingkat fatigue melalui latihan Progressive Muscle Relaxation (PMR) pada pasien Gagal Ginjal Kronis yang menjalani hemodialisa

2019 ◽  
Author(s):  
Santi Herlina
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Muscle Relaxation ◽  
Intervention Group ◽  
Nursing Intervention ◽  
Progressive Muscle Relaxation ◽  
Control Group ◽  
Before And After

Fatigue is a major complaint of patients undergoing long-term hemodialysis, which has a high value, so it will affect the quality of life of patients. The purpose of this study was to determine the influence of PMR on the level of fatigue in patients with chronic kidney disease undergoing hemodialysis. This study used a quasi experiment design approach pretest-posttest control group. The number of respondents in the study were 32 patients divided into 2 groups: the 16 intervention group and 16 control group. The research concludes that there are significant differences on the level of fatigue in the intervention group between before and after PMR with p = 0.000. Suggested training PMR can be used as an independent nursing intervention in reducing fatigue in patients with chronic kidney disease undergoing hemodialysis.

scholarly journals The improvement of elderly sleeping quality with progressive muscle relaxation therapy

2020 ◽  
Vol 7 (5) ◽  
pp. 1684
Author(s):  
Emira Apriyeni ◽  
Helena Patricia
Keyword(s):  
Sleep Quality ◽  
Sleep Disorders ◽  
Muscle Relaxation ◽  
The Elderly ◽  
Nursing Intervention ◽  
Progressive Muscle Relaxation ◽  
Control Group ◽  
Relaxation Therapy ◽  
Before And After

Background: Sleep is one part of physiological needs and it is a basic need which is needed by all humans to be able to function optimally. However, the elderly will often experience sleep disorders. Sleep disorders in the elderly will affect the quality of sleep. One of nursing intervention that can improve the elderly sleeping quality is progressive muscle relaxation therapy. This study aims to determine the differences of sleep quality before and after having progressive muscle relaxation therapy toward the elderly with sleep disorders.Methods: This research was conducted at the Tresna Werdha Sabai Nan Aluih Social Home, Sicincin in 2019. The research was conducted for 2 weeks with one-week intervention. This research is a Quasy experiment using one group pre-test and post-test without control group design approach. This study used the sample of 16 respondents taken by purposive sampling. The analysis of data uses dependent T-test with a significance level of 95% (α 0.05).Results: The results of the study found that the average sleep quality of the elderly before being given the intervention was 13.63 and after the intervention it became 8.44 with p value of 0.000.Conclusions: The results showed that there were significant differences before and after the intervention. For this reason, it is recommended for the elderly with sleep disorders to be able to do progressive muscle relaxation therapy to improve sleep quality.  

scholarly journals Manfaat Relaksasi Otot Progresif Bagi Klien DM Tipe II Untuk Mengurangi Gejala Fatigue

2021 ◽  
Vol 6 (2) ◽  
pp. 45-52
Author(s):  
Reny Sulistyowati
Keyword(s):  
Muscle Relaxation ◽  
Intervention Group ◽  
Progressive Muscle Relaxation ◽  
Wilcoxon Test ◽  
Bivariate Analysis ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Significant Difference ◽  
Before And After

Fatigue is a widespread clinical complaint among adults with type 2 diabetes. Fluctuating glucose levels can cause fatigue. Several factors are associated with fatigue in diabetic patients, including physiological factors such as hypoglycemia or hyperglycemia, psychological factors such as depression associated with diabetes. Progressive muscle relaxation is a procedure to get relaxation in the muscles through two steps, namely by applying tension to a muscle group and stopping the tension then focusing on how the muscle relaxes, feeling the sensation of relaxation and fatigue is reduced. The aim of this study was to identify the effect of progressive muscle relaxation on fatigue symptoms in type II DM clients in 15 control groups and 15 intervention groups. The research method used a quasi-experimental design with a pretest-posttest control group design approach, consisting of one treatment (in the intervention group) and a control group. Data analysis was performed using univariate and bivariate analysis using t-independent and t-dependent tests. Wilcoxon test results in the intervention group and the control group showed a significant p-value of 0.002 (<0.05), meaning that there was a significant difference in fatigue symptoms in the intervention group before and after the intervention. This shows that there was a decrease in fatigue symptoms in the intervention group before and after combination OHO therapy and progressive muscle relaxation exercises (previously the average respondent in the intervention group experienced symptoms of severe fatigue, after intervention, the average value of fatigue symptoms turned into mild fatigue ). Conclusion: Progressive muscle relaxation combined with OHO therapy can reduce symptoms of fatigue compared to only OHO therapy.

scholarly journals Health Education Through a Campaign and mHealth to Enhance Knowledge and Quality of Life Among Patients With Chronic Kidney Disease in Bangladesh: Protocol for a Randomized Controlled Trial (Preprint)

2021 ◽  
Author(s):  
Mohammad Habibur Rahman Sarker ◽  
Michiko Moriyama ◽  
Harun Ur Rashid ◽  
Md Moshiur Rahman ◽  
Mohammod Jobayer Chisti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Randomized Controlled Trial ◽  
Kidney Disease ◽  
Health Education ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Randomized Controlled

BACKGROUND Despite the growing burden of chronic kidney disease (CKD), disease knowledge and understanding are still lacking, especially in Bangladesh. OBJECTIVE The aim of this study was to evaluate the outcome of a health education intervention in order to enhance knowledge, health-related quality of life (QOL), and motivation regarding healthy lifestyles among rural and periurban adults suffering from CKD. METHODS A parallel-group (1:1) randomized controlled trial is ongoing in the Mirzapur subdistrict, Bangladesh, where two groups of patients with CKD are being compared. Patients aged 18 years and over with CKD (stages 1-3) were enrolled in November 2020. Patients were randomly allocated into either the intervention group (n=63) or the control group (n=63). The control group received usual treatment, while the intervention group received health education through a CKD campaign facilitated by a nephrologist and via mHealth (ie, periodic mobile phone calls) from community health workers. Both groups were followed up for a period of 6 months. The primary endpoint is patients’ increased knowledge measured using the Chronic Kidney Disease Knowledge Questionnaire. The secondary endpoints are improved QOL measured using the standardized EuroQol 5-Dimension 5-Level (EQ-5D-5L) questionnaire as well as improvements in the levels of blood pressure, BMI, serum creatinine, fasting blood sugar, hemoglobin, cholesterol, high-density lipoprotein cholesterol, triglyceride, serum uric acid, blood urea nitrogen, and albumin to creatinine ratio. RESULTS Enrollment of participants began in November 2020; the intervention and follow-up were completed in May 2021. We enrolled 126 patients in the study. Patients’ mean ages were 57.97 (SD 15.03) years in the control group and 57.32 (SD 14.37) years in the intervention group. There were 45 out of 63 (71%) females in the control group and 38 out of 63 (60%) females in the intervention group. In addition, there were 38 out of 63 (60%) literate patients in the control group and 33 out of 63 (52%) literate patients in the intervention group. CONCLUSIONS It is expected that a combined approach, incorporating both a CKD campaign and mHealth, for health education may be an effective tool for increasing knowledge and improving QOL among patients with CKD. CLINICALTRIAL ClinicalTrials.gov NCT04094831; https://clinicaltrials.gov/ct2/show/NCT04094831 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/30191

scholarly journals Health Education Through a Campaign and mHealth to Enhance Knowledge and Quality of Life Among Patients With Chronic Kidney Disease in Bangladesh: Protocol for a Randomized Controlled Trial

10.2196/30191 ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. e30191
Author(s):  
Mohammad Habibur Rahman Sarker ◽  
Michiko Moriyama ◽  
Harun Ur Rashid ◽  
Md Moshiur Rahman ◽  
Mohammod Jobayer Chisti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Randomized Controlled Trial ◽  
Kidney Disease ◽  
Health Education ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Randomized Controlled

Background Despite the growing burden of chronic kidney disease (CKD), disease knowledge and understanding are still lacking, especially in Bangladesh. Objective The aim of this study was to evaluate the outcome of a health education intervention in order to enhance knowledge, health-related quality of life (QOL), and motivation regarding healthy lifestyles among rural and periurban adults suffering from CKD. Methods A parallel-group (1:1) randomized controlled trial is ongoing in the Mirzapur subdistrict, Bangladesh, where two groups of patients with CKD are being compared. Patients aged 18 years and over with CKD (stages 1-3) were enrolled in November 2020. Patients were randomly allocated into either the intervention group (n=63) or the control group (n=63). The control group received usual treatment, while the intervention group received health education through a CKD campaign facilitated by a nephrologist and via mHealth (ie, periodic mobile phone calls) from community health workers. Both groups were followed up for a period of 6 months. The primary endpoint is patients’ increased knowledge measured using the Chronic Kidney Disease Knowledge Questionnaire. The secondary endpoints are improved QOL measured using the standardized EuroQol 5-Dimension 5-Level (EQ-5D-5L) questionnaire as well as improvements in the levels of blood pressure, BMI, serum creatinine, fasting blood sugar, hemoglobin, cholesterol, high-density lipoprotein cholesterol, triglyceride, serum uric acid, blood urea nitrogen, and albumin to creatinine ratio. Results Enrollment of participants began in November 2020; the intervention and follow-up were completed in May 2021. We enrolled 126 patients in the study. Patients’ mean ages were 57.97 (SD 15.03) years in the control group and 57.32 (SD 14.37) years in the intervention group. There were 45 out of 63 (71%) females in the control group and 38 out of 63 (60%) females in the intervention group. In addition, there were 38 out of 63 (60%) literate patients in the control group and 33 out of 63 (52%) literate patients in the intervention group. Conclusions It is expected that a combined approach, incorporating both a CKD campaign and mHealth, for health education may be an effective tool for increasing knowledge and improving QOL among patients with CKD. Trial Registration ClinicalTrials.gov NCT04094831; https://clinicaltrials.gov/ct2/show/NCT04094831 International Registered Report Identifier (IRRID) DERR1-10.2196/30191

scholarly journals The Effect of Progressive Muscle Relaxation on Post Cesarean Section Pain, Quality of Sleep and Physical Activities Limitation

2018 ◽  
Vol 3 (3) ◽  
pp. 14 ◽  
Author(s):  
Nemat Ismail Abdel Aziz Ismail ◽  
Wafaa Taha Ibrahim Elgzar
Keyword(s):  
Cesarean Section ◽  
Muscle Relaxation ◽  
Nursing Intervention ◽  
Physical Activities ◽  
Progressive Muscle Relaxation ◽  
Medical Institute ◽  
Control Group ◽  
Study Group ◽  
Quality Of Sleep

Background: Pain, sleep disturbances, and physical activity limitation are the most tiresome complains of the women post caesarian section (Cs). Progressive muscle relaxation is a promising intervention for these complains. This study aimed to determine the effect of progressive muscle relaxation technique on post-cesarean section pain, quality of sleep and physical activities limitation. Research design: Randomized controlled clinical trial. Setting: post-partum unit at Damanhour National Medical Institute. Sample: A purposive sample of 80 women undergoing Cs was recruited. Randomization block was done to randomly assign 40 women for the study group and 40 for the control group. Tools: Four tools were used for data collection: structured interview schedule, short-form McGill Pain Questionnaire, Physical activities limitation Questionnaire and Groningen Sleep Quality Scale. Results: After the intervention, PMR significantly decreased pain severity among study group in Pain Rating Index scale, Visual analogue pain scale, and Present Pain Intensity scale compared to the control group. The severe physical activities limitation significantly absent from the entire study group, while it was significantly present among 70% of the control group. About two-thirds (62.5%) of the study group had a good quality of sleep compared to 5% of the control group. Conclusion: PMR significantly decreased pain, improved physical activities and quality of sleep among women after Cs. Recommendation: PMR should be incorporated in the nursing intervention protocols post-Cs.

scholarly journals The Effect Of Progressive Muscle Relaxation On Sleep Quality In Patients With Hypertension In South Cilacap City

2017 ◽  
Vol 3 (2) ◽  
pp. 20 ◽  
Author(s):  
KASRON KASRON ◽  
SUSILAWATI SUSILAWATI
Keyword(s):  
Sleep Quality ◽  
Muscle Relaxation ◽  
Progressive Muscle Relaxation ◽  
Wilcoxon Test ◽  
Control Group ◽  
P Value ◽  
Care Programme ◽  
Hypertensive Patients ◽  
Before And After

Introduction : Patients with hypertension patients can have sleep disorders such as dizziness or headache, feeling tired during the day, anxiety, decreasing concentration and irritability. This study aimed to evaluate the effect of progressive muscle relaxation (PMR) on sleep quality in patients with hypertension in South Cilacap City. Method : The research used quasi-experiment with pre-post test without control group. Respondents werw patients with hypertension in South Cilacap City, with the criteria forthose who were active in health care programme, able to perform independent activities, consume of anti-hypertensive drugs, have done PMR regularly for 7 days, and the exclusion criteria was patients with impaired osteoarthritis and rheumatoid arthritis. Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality twice, before and 7 days after interventions PMR. Statistic analysis used wilcoxon test. 16 respondents included in the criteria. Result : The quality of sleep before treatment PMR was 7 people (43.8%) poor, 9 people (56.3%) very bad. After treatment PMR was 3 people (18.8%) rather good, 13 people (81.3%) less good. The analysis shown the sleep quality was difference between before and after PMR with p-value <0.001. Discussion : The study shows there is difference between before and after PMR in hypertensive patients in South Cilacap. PMR can be used to improve the sleep quality of hypertensive patients.

scholarly journals Pengaruh Latihan Relaksasi Otot Progresif terhadap Kualitas Tidur Lansia

1970 ◽  
Vol 4 (1) ◽  
Author(s):  
Sulidah Sulidah ◽  
Ahmad Yamin ◽  
Raini Diah Susanti
Keyword(s):  
Older People ◽  
Muscle Relaxation ◽  
Intervention Group ◽  
T Test ◽  
Progressive Muscle Relaxation ◽  
Control Group ◽  
Quality Of Sleep ◽  
Post Test ◽  
Relaxation Exercise

Lansia merupakan kelompok orang yang paling sering mengalami penurunan kualitas tidur. Beberapa penelitian menunjukkan manfaat latihan relaksasi otot progresif untuk menghadirkan rasa nyaman yang dibutuhkan dalam mereduksi penyebab gangguan tidur. Penelitian ini untuk mengidentifikasi pengaruh relaksasi otot progresif terhadap kualitas tidur lansia. Rancangan penelitian ini Quasi Experimental dengan pendekatan Pretest-Posttest Control Group Design. Sampel diambil secara Purposive Sampling. Besar sampel 51 responden, terdiri dari 26 responden kelompok intervensi dan 25 responden kelompok kontrol. Kelompok intervensi melakukan latihan relaksasi otot progresif selama empat minggu. Kualitas tidur diukur sebelum dan sesudah latihan relaksasi otot progresif menggunakan instrumen PSQI. Pengukuran dilakukan empat kali, yaitu sebelum intervensi (pre test), dua minggu setelah intervensi (post test 1), tiga minggu setelah intervensi (post test 2), dan empat minggu setelah intervensi (post test 3). Data dianalisis menggunakan t test dan Repeated Anova. Hasil Uji t berpasangan kelompok intervensi menunjukkan nilai t hitung > t tabel, dengan p = 0,000. Pada kelompok kontrol diperoleh nilai t hitung < t tabel, dengan p > 0,05. Uji Repeated Anova memeroleh nilai F hitung (71,415) > F tabel (3,89) dengan p=0,000. Uji t tidak berpasangan didapatkan skor pretest, posttest 1, posttest 2 dan posttest 3 berbeda signifikan antara kelompok intervensi dan kelompok kontrol dengan p < 0,05. Rata-rata skor PSQI kelompok intervensi menunjukkan kecenderungan penurunan setelah latihan relaksasi otot progresif, sedang kelompok kontrol tidak menunjukkan perubahan skor secara bermakna. Hal ini dimungkinkan karena latihan relaksasi otot progresif bermanfaat menimbulkan respon tenang, nyaman, dan rileks. Implikasi penelitian ini bahwa latihan relaksasi otot progresif secara bermakna meningkatkan kualitas tidur lansia sehingga dapat dipertimbangkan sebagai terapi komplementer dalam tatalaksana gangguan tidur pada lansia sebagai tindakan mandiri keperawatan.Kata kunci: Kualitas tidur, lansia, relaksasi otot progresif.The Effect of Progressive Muscle Relaxation Exercise towards Older People’s Quality of SleepAbstractOlder people are the group of people who often experience the decreasing of quality of sleep. Few studies showed the benefit of progressive muscle relaxation exercise to give comfort that is needed to reduce the cause of sleep disturbance. This study aimed to examine the effect of progressive muscle relaxation exercise towards older people’s quality of sleep. The research design is quasi experimental using pretest-posttest control group design. The sample were recruited using purposive sampling. The total sample were 51 participant which consist of 26 participants in intervention group and 25 participants in control group. Intervention group were conducted progressive muscle relaxation exercise for four weeks. The quality of sleep were measured before and after the exercise using PSQI instrument. The measurements were conducted four times, which were before intervention (pretest), two weeks after intervention (posttest 1), three weeks after intervention (posttest 2), and four weeks after intervention (posttest 3). The data were analyzed using t-test and Repeated ANOVA. The paired t-test for intervention group showed that the score of counted t > table t, with p = 0.000. In the control group, the results showed that counted t < table t score, p >0.005. The repeated ANOVA showed that counted F (71.415) > table F (3.89) with p= 0.000. Independent t-test showed that scores of pretest, posttest 1, posttest 2 and posttest 3 were different significantly between intervention and control groups with p<0.05. The average PSQI scores in intervention group showed a tendency of decreasing after progressive muscle relaxation exercise, while in the control group there was no significant changes in the scores. This is because the progressive muscle relaxation exercise is benefit to give calming, comforting and relaxing responses. The implication of this study is that progressive muscle relaxation exercise can significantly improve the quality of sleep of older people so that this exercise can be considered as a complementary therapy for management of sleep disturbance among older people as an independent nursing care.Keywords: Older people, progressive muscle relaxation exercise, quality of sleep.

scholarly journals THE APPLICATION OF ART THERAPY TO REDUCE THE LEVEL OF DEPRESSION IN PATIENTS WITH HEMODIALYSIS

2018 ◽  
Vol 4 (3) ◽  
pp. 329-335
Author(s):  
Atikah Fatmawati ◽  
M. Rachmat Soelaeman ◽  
Imas Rafiyah
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Art Therapy ◽  
Intervention Group ◽  
Psychological Adaptation ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Before And After ◽  
Quasi Experimental

Background: Depression can occur in patients with chronic kidney disease undergoing hemodialysis and can lead to decreased quality of life, and will have a two-fold risk for the occurrence of death and hospitalization. Objective: The purpose of this study was to identify the effects of art therapy on the level of depression patients with hemodialysis.Methods: This study used a quasi-experimental method with pretest posttest with control group design. Collecting data using questionnaires of Beck Depression Inventory (BDI-II) versions of Indonesia, which was done twice, before and after art therapy intervention. Data were analyzed using paired t-test and unpaired t-test.Results: The results showed that after given intervention of art therapy there were differences in the average scores of depression in the intervention group (t = 0.764; p-value = 0.000). Art therapy is a medium to expose and express the feelings, fears or perceived problem, so it can be used as an adaptive coping method in patients with chronic kidney disease undergoing hemodialysis. Conclusion: It is concluded that art therapy could reduce depression in patients with chronic kidney disease undergoing hemodialysis. Nurses can act as a facilitator to provide art-based therapy in order to improve the ability of psychological adaptation in patients with chronic kidney disease undergoing hemodialysis. 

scholarly journals The Effects of “Ceria” Chemotherapy Effect Management on the Life Quality Improvement of Children with Cancer

2019 ◽  
Vol 1 (1) ◽  
pp. 87-96
Author(s):  
Siti Lestari ◽  
Sri Hartini Mardi Asih ◽  
Rusmiyati Rusmiyati
Keyword(s):  
Quality Of Life ◽  
Quality Improvement ◽  
Treatment Group ◽  
Muscle Relaxation ◽  
Life Quality ◽  
Progressive Muscle Relaxation ◽  
Control Group ◽  
Children With Cancer ◽  
Before And After

The prevalence of cancer in children is now increasing and followed by an increasing number of them who undergo chemotherapy. The effect of chemotherapy can reduce the children’s quality of life, hence it requires the contribution of nurses in improving health services to children with cancer. The purpose of the study was to analyze the effect management of “Ceria” chemotherapy : (C)egah Sariawan (preventing mucositis), Cegah (E)kstravasasi (preventing extravacation), (R)elaksasi (Progressive Muscle Relaxation to reduce fatigue), Cegah (I)nfeksi (preventing infection), (A)kupresur (acupressur to reduce nausea and vomiting) on the life quality of children with cancer. The method applied was experimental research using control group design with pretest posttest. The treatment group received intervention in the form of “Ceria” chemotherapy effect management from the researchers while the control group did not receive intervention treatment. The selection of research subjects for the treatment and control groups was done randomly. The children’s quality of life was measured before and after one week of intervention using PedsQL (Children's Quality of Life Inventory). The participants were 76 children (38 in the treatment  group and 38 in the control group). The results of the paired t test showed that there were significant mean differences of life quality before and after "Ceria" chemotherapy effects management on children with cancer (p = 0,0001; sig = 0.05), the highest life quality improvement was found on children who experienced progressive muscle relaxation. This study concludes that "Ceria" chemotherapy effect management  can improve the life quality of children with cancer. Therefore, the reseachers recommend nurses to apply “Ceria” chemotherapy effect management to improve the life quality of children with cancer.   Keywords: cancer, children, quality of life,  "Ceria" chemotherapy effect management

scholarly journals Prebiotic Therapy with Inulin Associated with Low Protein Diet in Chronic Kidney Disease Patients: Evaluation of Nutritional, Cardiovascular and Psychocognitive Parameters

Toxins ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 381
Author(s):  
Silvia Lai ◽  
Sandro Mazzaferro ◽  
Maurizio Muscaritoli ◽  
Daniela Mastroluca ◽  
Massimo Testorio ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Intervention Group ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Control Group ◽  
Low Protein ◽  
Sf 36

A relationship between dysbiotic gut microbiome and chronic kidney disease (CKD) has been recently documented; it contributes to CKD-related complications, including cardiovascular disease. Aim: We tested how a low-protein diet (LPD)—with or without oral inulin supplementation as a prebiotic—modulates some inflammatory, atherosclerosis and endothelial dysfunction indices and nutritional markers, as well as psychocognitive functions in CKD patients. We conducted a prospective, case–control study on CKD patients on conservative therapy, divided in two groups: the intervention group treated with LPD (0.6 g/kg/day) plus inulin (19 g/day) and a control group treated with LPD without inulin, for six consecutive months. Clinical and hematochemical parameters as well as instrumental, and psychocognitive assessments (by SF-36 survey and MMSE, HAM-D, BDI-II) were recorded in all the participants at baseline (T0), at three months (T1) and at six months (T2). A total of 41 patients were enrolled: 18 in the intervention group and 23 in the control group. At T2, in both groups, we observed a significant reduction of serum nitrogen and phosphorus (p ≤ 0.01) and serum uric acid (p ≤ 0.03), and an improvement in metabolic acidosis (bicarbonates, p ≤ 0.01; base excess, p ≤ 0.02). Moreover, at T2 the intervention group showed a reduction in serum insulin (p = 0.008) and fasting glucose levels (p = 0.022), HOMA-IR (p = 0.004), as well as lower total serum cholesterol (p = 0.012), triglycerides (p = 0.016), C-reactive protein (p = 0.044) and homocysteine (p = 0.044) and higher HDL (p < 0.001) with respect to baseline. We also observed a significant amelioration of some quality of life and functional status indices (SF-36 survey) among the intervention group compared to controls, without a significant improvement in the cognitive state (MMSE). On the other hand, an amelioration in mood (by HAM-D and BDI-II) was found in the intervention group and in controls (only by BID-II). In conclusion, LPD in association with oral inulin supplementation improved glycemic and lipid metabolism and ameliorated the systemic inflammatory state, likely reducing cardiovascular risk in CKD patients and this may represent a promising therapeutic option, also improving quality of life and mood.

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