scholarly journals Examining the clinical utility of using affective dynamics to characterize and predict depression symptoms within a comorbid sample

2021 ◽  
Author(s):  
Marilyn Piccirillo ◽  
Madelyn Frumkin ◽  
Marilyn Piccirillo ◽  
Natasha April Tonge ◽  
Katherine T. Foster

Background: Dynamic indices calculated from ecological momentary assessment (EMA) data can model individual-level symptom fluctuations over time. However, the clinical utility for using these complex metrics to characterize comorbid symptomatology and to predict future symptom changes has not been adequately examined. Methods: Women (N = 35) with social anxiety disorder and a history of major depression completed a clinical diagnostic interview and self-report measures at baseline and approximately two months later. In between these assessments, participants completed EMA surveys on mood and anxiety symptoms five times a day for approximately 30 days (T = 5,250). Symptom severity and dynamic indices (i.e., variance, inertia) during EMA were calculated. The relative predictive value of these indices for characterizing baseline symptomatology, as well as the relative prospective predictive value of dynamic indices predicting future depressive symptomatology was assessed. Results: Baseline depressive symptoms were associated with mean levels of anxiety (b = .38, p = .001); whereas, baseline social anxiety symptoms were associated with mean levels of depression during EMA (b = -.38, p = .013). Moment-to-moment variance in anxiety during EMA (b = .22, p = .020) and baseline self-report measures of depression (b = .50, p < .001) predicted future depressive symptoms. Conclusions: Moment-to-moment fluctuations in anxiety may constitute a unique early warning sign of future increases in depression for individuals with mood and anxiety comorbidity.

2009 ◽  
Vol 15 (3) ◽  
pp. 393-398 ◽  
Author(s):  
K Poder ◽  
K Ghatavi ◽  
JD Fisk ◽  
TL Campbell ◽  
S Kisely ◽  
...  

Background Little is known about social anxiety in MS. Objective We estimated the prevalence of social anxiety symptoms and their association with demographic and clinical features in a clinic-attending sample of patients with MS. Methods Patients attending the Dalhousie MS Research Unit for regularly scheduled visits completed the Social Phobia Inventory (SPIN), the Hospital Anxiety and Depression Scale (HADS), and the Health Utilities Index (HUI). Neurological disability was determined by ratings on the Expanded Disability Status Scale (EDSS). Results A total of 251 patients completed self-report scales of anxiety and depression symptoms. In all, 245 (98%) provided sufficient data for analysis. In all, 30.6% ( n = 75) had clinically significant social anxiety symptoms as defined by a SPIN threshold score of 19. Half of those with social anxiety had general anxiety (HADSA ≥ 11) and a quarter had depression (HADSD ≥ 11). Severity of social anxiety symptoms was associated with reduced health-related quality of life and not related to neurological disability. Conclusions Social anxiety symptoms are common in persons with MS, contribute to overall morbidity, but are unrelated to the overall severity of neurologic disability. Greater awareness and routine systematic inquiry of social anxiety symptoms is an important component of comprehensive care for persons with MS.


SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A121-A122
Author(s):  
S T Nguyen-Rodriguez ◽  
O M Buxton

Abstract Introduction Chronotype refers to a preference for morning hours (morningness) vs. evening hours (eveningness) when individuals tend to feel their best (e.g., higher energy levels). People may be classified at either end of this spectrum or along a continuum between these preferences. Among adolescents, eveningness is positively related to depression and anxiety, whereas morningness is negatively related to depression. However, less is known about the relationship of chronotype and psychological health in pre-teens and Latinx youth. The present study explored associations of morningness/eveningness with anxiety symptoms, depressive symptoms, and perceived stress among Latinx pre-adolescents in Southern California. Methods A purposive sample of 100 Latinx children, ages 10-12 years old, completed self-report surveys in their homes or a preferred location chosen by the parent. Measures included the Morningness/Eveningness Scale for Children (higher scores indicate morning preference), Revised Child Anxiety and Depression Scale and the Perceived Stress Scale (higher scores indicate higher anxiety, depression and stress, respectively). Associations were tested with Pearson correlations. Results The sample was 47% male with a mean±SD age of 10.9±0.8 years. Average score for morningness/eveningness was M=30.2±4.4 (range: 18-41), for anxiety symptoms was M=0.7±0.7 (range: 0-2.8), for depression symptoms was M=0.5±0.4 (range: 0-1.9) and for perceived stress was M=15.2±5.8 (range: 2-30). Greater morningness/eveningness scores, indicating more morningness, were associated with lower scores for anxiety symptoms (r=-.41, p<.001), depressive symptoms (r=-.36, p<.001) and perceived stress (r=-.33, p=.001). Conclusion As has been found for adolescents, higher morningness in Latinx pre-teens was related to less frequent anxiety and depression symptoms, as well as lower perceived stress. Youth experience a circadian phase delay during adolescence, shifting their preference toward eveningness, which may exacerbate stressors and negative mental health. Therefore, interventions to promote psychological well-being in pre-adolescents may help prevent worse psychological outcomes in Latinx children as they transition to adolescence. Support This work was supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Numbers UL1GM118979, TL4GM118980, and RL5GM118978.


Assessment ◽  
2021 ◽  
pp. 107319112098388
Author(s):  
Kevin M. King ◽  
Max A. Halvorson ◽  
Kevin S. Kuehn ◽  
Madison C. Feil ◽  
Liliana J. Lengua

There is a small body of research that has connected individual differences in negative urgency, the tendency to report rash actions in response to negative emotions, with self-report depressive and anxiety symptoms. Despite the conceptual overlap of negative urgency with negative emotionality, the tendency to experience frequent and intense negative emotions, even fewer studies have examined whether the association of negative urgency with internalizing symptoms hold when controlling for negative emotionality. In the current study, we estimated the bivariate association between negative urgency and internalizing symptoms, tested whether they remained significant after partialling out negative emotionality, and tested whether these effects generalized to real-time experiences of negative emotions. We used data from five independent samples of high school and college students, assessed with global self-report ( n = 1,297) and ecological momentary assessment ( n = 195). Results indicated that in global self-report data, negative urgency was moderately and positively associated with depressive and anxiety symptoms, and the partial association with depressive symptoms (but not anxiety symptoms) controlling for negative emotionality remained significant and moderate in magnitude. This pattern was replicated in ecological momentary assessment data. Negative urgency may convey risk for depressive symptoms, independent of the effects of negative emotionality.


1989 ◽  
Vol 14 (3) ◽  
pp. 166-174 ◽  
Author(s):  
Betty C. Epanchin ◽  
Mary Sue Rennells

The primary purpose of this study was to investigate parents' and teachers' sensitivity to the unhappiness and depression of 110 elementary-aged undercontrolled children being treated in an inpatient program. Sensitivity was operationally defined as congruence between the child's responses on two self-report measures (Children's Depression Inventory and Hopelessness Scale for Children) and the adults' behavioral ratings of the children on behavior checklists (Child Behavior Checklist and Teacher Report Form). The first hypothesis that children's self-reports of depressive symptoms would not be significantly correlated with parents' and teachers' ratings of depressive symptomatology was supported. Secondly, it was hypothesized that there would be no differences in the level of self-reported depressive symptoms when children who were rated as depressed by their parents and teachers were compared with children rated as not depressed by their parents and teachers. This was also supported. Finally, it was hypothesized that children who reported significant levels of depressive symptomatology would be rated by their parents and teachers as having more behavior problems than children who did not report significant levels of depressed symptomatology. This was partially supported. The implications of these results in relation to identification and treatment are discussed.


2019 ◽  
Author(s):  
Alexandra C Pike ◽  
Frida Printzlau ◽  
Alexander H. von Lautz ◽  
catherine harmer ◽  
Mark G. Stokes ◽  
...  

Mood and anxiety disorders are associated with deficits in attentional control involving emotive and non-emotive stimuli. Current theories focus on impaired attentional inhibition of distracting stimuli in producing these deficits. However, standard attention tasks struggle to separate distractor inhibition from target facilitation. Here, we investigate whether distractor inhibition underlies these deficits using neutral stimuli in a behavioural task specifically designed to tease apart these two attentional processes. Healthy participants performed a four-location Posner cueing paradigm and completed self-report questionnaires measuring depressive symptoms and trait anxiety. Using regression analyses, we found no relationship between distractor inhibition and mood symptoms or trait anxiety. However, we find a relationship between target facilitation and depression. Specifically, higher depressive symptoms were associated with reduced target facilitation in a task-version in which the target location repeated over a block of trials. We suggest this may relate to findings previously linking depression with deficits in predictive coding in clinical populations.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Simeng Gu ◽  
Yawen Li ◽  
Fei Liang ◽  
Rou Feng ◽  
Zhi Zeng ◽  
...  

Mindfulness training has gained popularity in the scientific field and has been proposed as an efficient way for emotional regulation. Mindfulness-based cognitive therapy (MBCT) is designed especially for depressive people in reducing risk of depression relapse and is recommended in national guidelines as a treatment choice for relapse prevention in recurrent depression. The aim of the current study was to investigate the effects of mindfulness training on depressive symptoms of international students and probe into the mediating role of mindfulness in stressful events and depression. In addition, we introduced a new kind of mindfulness training, the breathing exercise-based mindfulness training, which is based on the integration of Buddhism and Daoism. Self-report questionnaires assessing the coping style, abnormal depressive behavior, and stressful live events were completed in 260 international students in China (mean age=21.4 years). The results showed that (1) many international students showed depression symptoms, (2) stressful life events play a completely mediating role in the initiation of depression and anxiety, and (3) mindfulness training for 8 weeks significantly reduced the depressive symptoms, and it was also related to a positive coping style. This study has certain theoretical significance in exploring the mechanism of the occurrence and development of depression among international students and provides useful tools for this special group of international students. In addition, the international students can also learn Chinese culture through the training. These findings indicate that mindfulness training and positive coping style are interrelated with treating depressive symptoms for international students.


2020 ◽  
pp. 026988112095404
Author(s):  
Roger S McIntyre ◽  
Nelson B Rodrigues ◽  
Orly Lipsitz ◽  
Flora Nasri ◽  
Hartej Gill ◽  
...  

Background: Individuals meeting criteria for treatment-resistant depression (TRD) are differentially affected by high levels of anxiety symptoms. Aims: There is a need to identify the efficacy of novel rapid-onset treatments in adults with mood disorders and comorbid anxious-distress. Methods: This study included patients with treatment-resistant major depressive disorder (MDD) or bipolar disorder (BD) who were receiving intravenous (IV) ketamine treatment at a community-based clinic.Anxious-distress was proxied using items from the Quick Inventory of Depressive Symptomatology–Self Report 16-item (QIDS-SR16) and Generalized Anxiety Disorder 7-item (GAD7) scales. The difference in QIDS-SR16 total score, QIDS-SR16 suicidal ideation (SI) item and GAD7 score were analyzed between groups. Results: A total of 209 adults with MDD ( n = 177) and BD ( n = 26) were included in this analysis. From this sample, 94 patients (mean = 45 ± 13.9 years) met the criteria for anxious-distress. Individuals meeting the criteria for anxious-distress exhibited a significantly greater reduction in QIDS-SR16 total score following four infusions ( p = 0.02) when compared with patients not meeting the anxious-distress criteria. Both anxious-distressed and low-anxiety patients exhibited a significant reduction in SI ( p < 0.0001) following four infusions.Finally, there was a significantly greater reduction in anxiety symptoms in the anxious-distress group compared with the non–anxious distress group following three ( p = 0.02) and four infusions ( p < 0.001). Conclusion: Patients with TRD and prominent anxiety receiving IV ketamine exhibited a significant reduction in depressive, SI and anxiety symptoms.


Author(s):  
Rebecca E. Anthony ◽  
Amy L. Paine ◽  
Katherine H. Shelton

The mental health of birth parents has gained attention due to the serious negative consequences for personal, family, and child outcomes, but depression and anxiety in adoptive parents remains under-recognized. Using a prospective, longitudinal design, we investigated anxiety and depression symptoms in 96 British adoptive parents over four time points in the first four years of an adoptive placement. Depression and anxiety symptom scores were relatively stable across time. Growth curve analysis showed that higher child internalizing scores and lower parental sense of competency at five months post-placement were associated with higher initial levels of parental depressive symptoms. Lower parental sense of competency was also associated with higher initial levels of parental anxiety symptoms. Parents of older children and those with higher levels of parental anxiety and sense of competency at five months post-placement had a steeper decrease in depressive symptoms over time. Support for adoptive families primarily focuses on child adjustment. Our findings suggest that professional awareness of parental mental health post-placement may be necessary, and interventions aimed at improving parents’ sense of competency may be beneficial.


2003 ◽  
Vol 33 (4) ◽  
pp. 611-622 ◽  
Author(s):  
T. I. ZAIDER ◽  
R. G. HEIMBERG ◽  
D. M. FRESCO ◽  
F. R. SCHNEIER ◽  
M. R. LIEBOWITZ

Background. The clinical Global Impression Scale (CGI) is commonly used as a primary outcome measure in studies evaluating the efficacy of treatments for anxiety disorders. The current study evaluated the psychometric properties and predictors of clinicians' ratings on an adapted version of the CGI among individuals with social anxiety disorders.Method. An independent assessor administered the CGI Severity of Illness and Improvement ratings to 123 patients at baseline and the subset of treated patients again mid- and post-treatment.Results. Improvement ratings were strongly related to both concurrent Severity of Illness and changes in Severity of Illness ratings from baseline. Additionally, both CGI ratings were positively correlated with both self-report and clinician-administered measures of social anxiety, depression, impairment and quality of life. Measures of social anxiety symptoms accounted for a large portion of the variance in Severity of Illness ratings, with significant additional variance accounted for by measures of impairment and depression. Changes in social anxiety symptoms from baseline accounted for significant variance in Improvement ratings, but no significant additional variance was accounted for by changes in impairment and depressive symptoms.Conclusions. Our findings support the utility of the CGI as an index of global severity and symptom-specific improvement among individuals with social anxiety disorder.


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