scholarly journals Normotensive HELLP syndrome in the midst of Dengue fever

2018 ◽  
Vol 9 (2) ◽  
pp. 40-42
Author(s):  
Robin George Manappallil ◽  
Sithara Surendran ◽  
Anoop Kumar ◽  
Ganga Prasad
Keyword(s):  
Blood Pressure ◽  
Risk Factor ◽  
Dengue Fever ◽  
Hellp Syndrome ◽  
Liver Enzymes ◽  
Elevated Blood ◽  
Medical Sciences ◽  
Elevated Liver Enzymes ◽  
Life Threatening ◽  
Life Threatening Complication

HELLP syndrome is a life threatening complication of pregnancy, characterized by haemolysis, elevated liver enzymes and low platelet counts. Preeclampsia is a risk factor for developing HELLP. However, some patients can have HELLP in the absence of elevated blood pressure. Dengue fever is a mosquito-borne viral infection characterized by fever, leucopenia and thrombocytopenia, and bleeding manifestations. This is a case of a young primigravida who presented with dengue fever and was found to have an associated normotensive HELLP syndrome.Asian Journal of Medical Sciences Vol.9(2) 2018 40-42

scholarly journals HELLP syndrome complicated by pulmonary edema: a case report

Open Medicine ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. 509-511
Author(s):  
Caiyuan Mai ◽  
Bin Wang ◽  
Rong Chen ◽  
Dongmei Duan ◽  
Lijuan Lv ◽  
...  
Keyword(s):  
Case Report ◽  
Caesarean Section ◽  
Early Detection ◽  
Pulmonary Edema ◽  
Hellp Syndrome ◽  
Liver Enzymes ◽  
Common Life ◽  
Elevated Liver Enzymes ◽  
Life Threatening ◽  
Life Threatening Complication

AbstractHELLP syndrome is a combination of symptoms described as hemolysis, elevated liver enzymes and low platelets. HELLP is a common life-threatening complication of pregnancy thought to be a variant or complication of preeclampsia. In this case report, we aimed to present a woman with acute postpartum HELLP syndrome complicated by pulmonary edema after caesarean section following severe preeclampsia. Our experience suggests that early detection of HELLP syndrome and timely management will bring good outcomes.

Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency

2004 ◽  
Vol 42 (10) ◽  
Author(s):  
Wolfgang Herrmann ◽  
Ulrich Hübner ◽  
Ines Koch ◽  
Rima Obeid ◽  
Ulrich Retzke ◽  
...  
Keyword(s):  
Renal Function ◽  
Risk Factor ◽  
Hellp Syndrome ◽  
Liver Enzymes ◽  
Methylmalonic Acid ◽  
Placental Insufficiency ◽  
B Vitamins ◽  
Fasting Serum ◽  
Obstetrical Complications ◽  
Elevated Liver Enzymes

AbstractHyperhomocysteinemia is a risk factor in obstetrical complications such as pre-eclampsia, ‘hemolysis, elevated liver enzymes, low platelet’ (HELLP)-syndrome and placental insufficiency. The aim of our study was to investigate the alterations of homocysteine catabolism in these patients in relation to serum B-vitamins and renal function. Maternal fasting serum from preeclampsia (n = 24), HELLP (n = 20) and placental insufficiency (n = 25) patients at the time of diagnosis and pregnant controls (n = 34) was analyzed for homocysteine and its metabolites cystathionine and methylmalonic acid, the vitamins B

scholarly journals HELLP syndrome against the background of glomerulonephritis: Clinical casereport

2019 ◽  
pp. 27-30
Author(s):  
L. Lebid ◽  
L. Snisar ◽  
L. Liksunova
Keyword(s):  
Hellp Syndrome ◽  
Laboratory Tests ◽  
Clinical Presentation ◽  
Liver Enzymes ◽  
Morbidity And Mortality ◽  
Chronic Glomerulonephritis ◽  
Medical Sciences ◽  
Severe Morbidity ◽  
Elevated Liver Enzymes

 HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) is a severe and rapidly progressing condition that requires distinct diagnostic considerations. The clinical presentation varied within all of the classes, and the only objective means of diagnosis and evaluation of progression of the condition are laboratory tests. HELLP syndrome may result in severe morbidity and mortality to both the mother and fetus. In this case, we reported that a patient with chronic glomerulonephritis was diagnosed with HELLP syndrome.The case was collected in Institute of Nephrology of the National Academy of Medical Sciences, Kyiv, Ukraine.

High predictability of impaired glucose tolerance by combining cardiometabolic screening parameters in obese children

2017 ◽  
Vol 30 (2) ◽  
Author(s):  
Cornelis Jan de Groot ◽  
Jeroen van der Grond ◽  
Yosine Delgado ◽  
Edmond H.H.M. Rings ◽  
Sabine E. Hannema ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Liver Enzymes ◽  
Elevated Blood Pressure ◽  
Oral Glucose ◽  
Elevated Blood ◽  
Obese Children ◽  
Number Needed To Screen ◽  
Elevated Liver Enzymes

AbstractBackground:There is debate on which overweight and obese children should be screened for the presence of impaired glucose tolerance (IGT) by oral glucose tolerance testing (OGTT). The objective of the study was to identify risk factors predictive of the presence of IGT.Methods:In a cohort of overweight children, who underwent OGTT, we determined the association of anthropometric and laboratory parameters with IGT and whether combining parameters improved the sensitivity of screening for IGT.Results:Out of 145 patients, IGT was present in 11, of whom two had impaired fasting glucose (IFG). Elevated blood pressure (p=0.025) and elevated liver enzymes (p=0.003) were associated with IGT, whereas IFG was not (p=0.067), screening patients with either one of these parameters predicted IGT with a high sensitivity of 1.00, and a number needed to screen of 5.7.Conclusions:Screening all patients with either IFG, presence of elevated blood pressure and elevated liver enzymes, significantly increases predictability of IGT compared to using IFG alone.

scholarly journals Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature

2021 ◽  
Vol 8 ◽  
Author(s):  
Valentina Messina ◽  
Daniele Dondossola ◽  
Maria Chiara Paleari ◽  
Gianluca Fornoni ◽  
Daniela Tubiolo ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hellp Syndrome ◽  
Multidisciplinary Approach ◽  
Liver Enzymes ◽  
Case Presentation ◽  
Foetal Growth Restriction ◽  
Elevated Liver Enzymes ◽  
Life Threatening ◽  
Low Platelet Count ◽  
Liver Bleeding

Background: Liver bleeding secondary to haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome is uncommon, but a life-threatening peripartum condition that needs a prompt multidisciplinary approach.Case Presentation: In this study, we presented a case of 28-year-old pregnant woman, who was presented to the obstetrics department with signs of preeclampsia and foetal growth restriction. An emergency caesarean section was performed, and the patient developed a HELLP syndrome complicated by spontaneous liver rupture. After radiological and surgical procedures, liver failure became evident and liver transplantation was successfully performed. The patient and her daughter are now alive.Conclusions: Despite the rarity of this disease, liver complications due to HELLP syndrome must be properly diagnosed and treated given the gravity of the possible evolution in young women. After diagnosis, the patients must be treated in specialised centres with gynaecological, liver surgery, and transplant skills.

scholarly journals Haemolysis, elevated liver enzymes and low platelets: Diagnosis and management in critical care

2021 ◽  
pp. 175114372110254
Author(s):  
Evangelia Poimenidi ◽  
Yavor Metodiev ◽  
Natasha Nicole Archer ◽  
Richard Jackson ◽  
Mansoor Nawaz Bangash ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Critical Care ◽  
Liver Failure ◽  
Hellp Syndrome ◽  
Seizure Control ◽  
Liver Enzymes ◽  
Kidney Injury ◽  
Definitive Treatment ◽  
Multisystem Disease ◽  
Elevated Liver Enzymes

A thirty-year-old pregnant woman was admitted to hospital with headache and gastrointestinal discomfort. She developed peripheral oedema and had an emergency caesarean section following an episode of tonic-clonic seizures. Her delivery was further complicated by postpartum haemorrhage and she was admitted to the Intensive Care Unit (ICU) for further resuscitation and seizure control which required infusions of magnesium and multiple anticonvulsants. Despite haemodynamic optimisation she developed an acute kidney injury with evidence of liver damage, thrombocytopenia and haemolysis. Haemolysis, Elevated Liver enzymes and Low Platelets (HELLP) syndrome, a multisystem disease of advanced pregnancy which overlaps with pre-eclampsia, was diagnosed. HELLP syndrome is associated with a range of complications which may require critical care support, including placental abruption and foetal loss, acute kidney injury, microangiopathic haemolytic anaemia, acute liver failure and liver capsule rupture. Definitive treatment of HELLP is delivery of the fetus and in its most severe forms requires admission to the ICU for multiorgan support. Therapeutic strategies in ICU are mainly supportive and include blood pressure control, meticulous fluid balance and possibly escalation to renal replacement therapy, mechanical ventilation, neuroprotection, seizure control, and management of liver failure-related complications. Multidisciplinary input is essential for optimal treatment.

scholarly journals Hemolysis, Elevated Liver Enzymes and Low Platelet (HELLP) Syndrome Associated with Systemic Lupus Erythematosus

2003 ◽  
Vol 42 (10) ◽  
pp. 1052-1053 ◽  
Author(s):  
Masayuki MATSUDA ◽  
Shigeaki MITSUHASHI ◽  
Megumi WATARAI ◽  
Kanji YAMAMOTO ◽  
Takao HASHIMOTO ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Hellp Syndrome ◽  
Liver Enzymes ◽  
Systemic Lupus ◽  
Elevated Liver Enzymes
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