scholarly journals A Clinico-Histopathological Study of Orbital and Ocular Lesions; a Multicenter Study

2013 ◽  
Vol 3 (2) ◽  
pp. 40-44 ◽  
Author(s):  
P Bastola ◽  
S Koirala ◽  
G Pokhrel ◽  
P Ghimire ◽  
RK Adhikari

The study aimed at finding out the morphological and clinico-pathological correlation of Orbital and Ophthalmic lesions in various eye institutes of Nepal. The study also aimed at finding out the prevalence of Ophthalmic lesions needing histo­pathological examination. This cross sectional descriptive study was carried out in various tertiary eye hospitals of Nepal from 2008 – 2012. The department of pathology was also incorporated in giving the correct histopathological findings in time. All the relevant data were entered in a specifically designed proforma for the study and analyzed. One hundred Oph­thalmic and Orbital lesions were studied in various age groups. Ophthalmic and Orbital lesions were highest (18%) in 31-40 year age group patients. Eyelid (57%) was the most commonly involved site. Clinical diagnosis was consistent with histo­pathological diagnosis in more than 60% of the cases. Among eyelid lesions, incidence of dermoid cyst (21%) was highest. While in Conjunctival lesions, granuloma pyogenicum (22.5%) was highest followed by other lesions. A clinico-patho­logical diagnosis of malignant orbital tumors or ocular tumors was made in 30% of cases. While 70% cases of Ophthalmic or orbital lesions were benign in nature. All Ophthalmic lesions removed surgically should always (without exception) be subjected to histopathological examination to establish correct diagnosis for further management. However this study has shown that a good clinical examination and diagnosis before subjecting the patient for histopathological examination gives the patient and the treating surgeon a better outcome. DOI: http://dx.doi.org/10.3126/jcmc.v3i2.8442 Journal of Chitwan Medical College Vol.3(2) 2013 40-44

2017 ◽  
Vol 11 (1) ◽  
pp. 5-10
Author(s):  
Rita Paul ◽  
Md Nasimul Islam ◽  
Enamul Kabir ◽  
Harunur Rashid Khan ◽  
Utpal Kumar Kundu

Background and objective: Eyelid growth is a common clinical condition presented to ophthalmologists. Accurate diagnosis of eyelid tumors is necessary to guide ophthalmologists to design optimal management. We carried out the study to assess the histopathological types of different eyelid growth in tertiarycare hospitals of Dhaka city.Methods: This is a cross sectional study performed at the Department of Pathology of Sir Salimullah Medical College (SSMC), Dhaka, Bangladesh. Samples were collected from hospitals of SSMC and National Institute of Ophthalmology (NIO), Dhaka, Bangladesh. Study period was from January 2012 to December 2013. A total of 93 cases with eyelid growth of both sex were enrolled in the study. After obtaining informed written consent, tumors were excised by the ophthalmologist and the specimens were collected in 10% formalin for histopathological examination.Results: A total of 93 cases of eyelid lesions were examined. The most common age group affected was between 26-50yrs (50.54%). Mean age was 43.22±17.42 (range 19 – 90 years). Gender distribution of the patients was almost equal (male 51.6%, female 48.4%). Neoplastic lesions were found in 86 cases (92.47%) and non neoplastic growth was present in 7 (7.53%) cases. Benign, pre-malignant and malignant tumors were found in 52 (55.91%), 01(1.08%) and 33(35.48%) cases respectively. Among the malignant lesions, basal cell carcinoma was the most common malignant tumor (36.4%) followed by sebaceous gland and squamous cell carcinoma (27.3%). Nevus was the most common benign lesions (26.9%) followed by sudoriferous cyst (19.2%) and haemangioma (15.4%).Conclusions: All the eyelid lesions removed surgically should be examined histopathologically to establish the correct diagnosis. Accurate diagnosis of specific tumors is important for proper treatment and favorable prognosis.IMC J Med Sci 2017; 11(1): 5-10


2020 ◽  
Vol 5 (2) ◽  
pp. 1104-1109
Author(s):  
Santosh Upadhyaya Kafle ◽  
Mrinalini Singh ◽  
Neeta Kafle ◽  
Amrita Sinha

Introduction: The histopathological examination of appendectomy specimens is the gold standard method for diagnosis. The presence of eosinophil besides other inflammatory cells like neutrophils and mature lymphocytes within different histological layers of appendectomy specimens are common findings for labeling it under various groups. This finding supports the assumption that appendicitis is triggered by Type 1 hypersensitivity reaction.  Objective: To evaluate the eosinophil count variation in appendectomy specimens in patients with the clinical diagnosis of appendicitis.  Methodology: This is a cross sectional hospital based study of 144 appendectomy specimens obtained in Department of Pathology, Birat Medical College Teaching Hospital from January 2019 to December 2019. Socio-demographic data, association of histopathological patterns with age groups, gender and eosinophil count in various histopathological groups was compared and cross-tabulated using SPSS version 16.  Result: Among 144 appendectomy specimens, male gender (50.70%) of 15-24 years age group (36.80%) was predominant. The commonest histopathological diagnosis was acute appendicitis (31.25%) with highest eosinophil count in all of its histological layers. The association of various histopathological patterns with age groups and gender were not statistically significant, whereas it revealed statistically significant correlation between eosinophil counts in all histological layers.  Conclusion: Findings suggest that the eosinophil count variation in the entire histological layers correlate well among different histopathological patterns of appendectomy specimens. This reflects the high diagnostic value of evaluating the eosinophil count in appendectomy specimens. 


2020 ◽  
pp. 15-18
Author(s):  
Baro Baneswar ◽  
Sarma Usha ◽  
Talukdar KL ◽  
Dutta BC ◽  
Sarma Tapan ◽  
...  

The seriousness of pancreatic diseases and the utmost importance of its correct diagnosis and treatment are expected to be helpful in correlating the functional capacity for further study in basic science and in decision making in clinical settings especially in transplant surgery of pancreas. Knowledge of normal morphometry of pancreas in living subjects is essential for understanding the segmental resection of pancreas as well as pancreatic imaging. A descriptive and cross-sectional study was conducted in the Department of Anatomy, Forensic Medicine & Pathology of Gauhati Medical College, Guwahati from May, 2016 to December 2019 on 103 specimens of human pancreas from 13 to 78 years age of both sexes. The collected samples were divided into seven age groups: A (10-19 years), B (20-29 years), C (30-39 years), D (40-49 years), E (50-59 years), F (60-69 years) and G (≥70 years), for convenient description. The differences between length of pancreas were statistically significant in A vs C, A vs D, A vs E, A vs F, A vs G, B vs C, B vs D, B vs E, B vs F and B vs G. The differences between weight of pancreas were statistically significant in A vs F, B vs C, B vs G, C vs D, C vs F, D vs F, E vs F, E vs G and F vs G. The present study is expected to standardize the morphology of pancreas in Assamese population.


1970 ◽  
Vol 4 (2) ◽  
pp. 74-77
Author(s):  
Rukshana Ahmed ◽  
Shamim Ara

Pathological changes in the prostate gland occur commonly with advancing age including inflammation, atrophy, hyperplasia and carcinoma and a change in volume is also evident. Estimation of volume of prostate may be useful in a variety of clinical settings. A cross-sectional descriptive study was designed to see the changes in volume of the prostate with advancing age and done in the Department of Anatomy, Dhaka Medical College, Dhaka from August 2006 to June 2007. The study was performed on 70 post-mortem human prostates collected from the unclaimed dead bodies that were under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age groups; group A (10-20 years), group B (21-40 years) and group C (41-70 years). Volume of the sample was measured by using the ellipsoid formula. The mean ± SD volume of prostate was 7.68 ± 3.64 cm3 in group A, 10.61 ± 3.99 cm3 in group B and 15.40 ± 6.31 cm3 in group C. Mean difference in volume between group A and group C, group B and group C were statistically significant (p<0.001). Statistically significant positive correlation was found between age and volume of prostate (r = + 0.579, p < 0.001). Key Words: Prostate; volume; Bangladeshi. DOI: 10.3329/imcj.v4i2.6501Ibrahim Med. Coll. J. 2010; 4(2): 74-77


2021 ◽  
pp. 9-11
Author(s):  
Durga Nand Jha ◽  
Hari Shankar Mishra ◽  
Ajit Kumar Chaudhary ◽  
Debarshi Jana

Background:Tumours and tumour like lesions of the colon and rectum have overlapping clinical presentation and may be difcult to diagnose on clinical grounds alone. Histopathological examination although helpful to arrive at correct diagnosis, at times may be difcult and may require ancillary tests such as immunohistochemistry. Materials and Methods: A prospective cross sectional study enrolled 125 cases of colorectal biopsies after histopathological conrmation of tumours and tumour like lesions. The specimens were received at the Department of Pathology, DMCH, Laheriasarai, Bihar from December 2019 to November 2020. Results: Out of 125 cases, 32 cases were benign tumours, 36 cases were malignant tumours and 57 cases were tumour like lesions. Most common age range was 51-60 years with mean age of 38 years. Males comprised 76.74% and females 23.26% with ratio of 3:1. Juvenile polyp was the commonest lesion. Among benign tumours, tubular adenoma was the most common (19.2%), adenocarcinoma was most common malignant tumour (25.6%) and juvenile polyp was the most common tumour like lesion (27.2%). Left side was most common side (66.67%) and rectum was the most common site (48.8%). Conclusions: The commonest indications for colorectal biopsies were tumours and tumour like lesions. Juvenile polyp was the most common tumour like lesion, tubular adenoma was the most common benign tumour and adenocarcinoma was the most common malignant tumour. Histopathological examination is a gold standard for conrmation of all tumour and tumours like lesions of colon and rectum.


2016 ◽  
Vol 5 (2) ◽  
pp. 26-28
Author(s):  
Zubaida Gulshan Ara ◽  
ASM Shafiqul Islam ◽  
Umme Kulsum Sharmin Zaman ◽  
Anjuman Ara ◽  
Reeva Aireen Busreea

This cross sectional descriptive study was done to see the length of the cervix in Bangladeshi cadaver to find out the anatomical variation and to compare it with other study findings. 60 post mortem specimens containing female genital organs particularly uterine cervix were collected by purposive sampling technique from cadavers of different age groups. All the collected specimens were fixed in 10% formalin solution. This study was carried out in the department of Anatomy, Mymensingh Medical College from July 2006 to June 2007. Both gross and fine dissections were performed to measure the length of the uterine cervix. We compare our study findings with that of the references. Maximum mean length of the cervix was found in the 13-45 years age group. It was 2.89 cm. CBMJ 2016 July: Vol. 05 No. 02 P: 26-28


2020 ◽  
Vol 7 (2) ◽  
pp. 80-83
Author(s):  
Sanjida Amin ◽  
Shamim Ara ◽  
Rawshon Naznin ◽  
Umma Marium ◽  
Farah Diba ◽  
...  

Background: Tendo Achilles injuries are usually related to poor ankle flexibility and strength and to overuse. Morphology of tendo Achilles is an important tool for its assessment which can be done by measuring tendon thickness, cross-sectional area and length of tendon. Objective: The aim of the study was to correlate length of tendo Achilles with stature in several age groups of sedentary people as measured by ultrasonography. Materials and method: This cross sectional analytical type of study was conducted in the department of Anatomy, Dhaka Medical College Hospital, Dhaka, Bangladesh from July 2013 to June 2014. The present study was performed on 200 tendo Achilles of 100 people (50 male and 50 female) randomly selected from the patients who came to the Radiology department of Dhaka Medical College Hospital for ultrasonography of any region of their body other than leg. Results: In this study length of tendo Achilles was measured in both legs of adult people and was correlated with stature. Highly significant correlation was found between length of tendo Achilles with stature (p<0.001). Conclusion: The data of length of tendo Achilles obtained from the present study may provide valuable information in different aspects of medical science as a guide line for physiotherapists, radiologists, sports professionals and ortho-surgeons in early detection and monitoring of rehabilitation especially of professional athletes. Delta Med Col J. Jul 2019 7(2): 80-83


2018 ◽  
Vol 8 (1) ◽  
pp. 1285-1288
Author(s):  
Sailesh Bahadur Pradhan ◽  
Binita Pradhan ◽  
Sailuja Maharjan ◽  
Prabin Bikram Thapa

Background: Gastrointestinal tract tumour is responsible for more cancers and death than any other cancers.  The tumour in GIT include the tumour of the Oral cavity, Esophagus, Stomach, Colon, Rectum, Liver, Gallbladder, Pancreas and Biliary tree.Materials and methods: A cross sectional study was carried out among all the gastrointestinal tract tumours specimens received for histopathological examination in between January 2016 to June 2017 in Department of Pathology, Kathmandu Medical College Teaching Hospital. All tumors diagnosed either benign or malignant were included in this study. Ethical clearance was obtained from the Institutional Review Committee in KMCTH.Results: Colorectum was found to be the most commonly involved site for malignant lesion comprising 40.2% among all malignant lesions followed by stomach comprising 28.6%. Malignancy was found to be more prevalent among male with M:F ratio of 1.6:1 in colorectal region and 1.4:1 in stomach cancers. Regarding benign lesions (polyps), rectum was found to be the commonest site (57.5%), followed by colon (20.0%) and stomach, the least common site.Malignant lesions were more common among the age group of 51-60 years (37.66%) with 70.13% above 50 years. Benign lesions were also found to be the most common above 50 years comprising 40.0 percent.Conclusion: Rectum & colon was found to be the most commonly involved site for both malignant and benign lesion. Malignancy is more prevalent among male and common above 50 years of age. However, malignant cases noted in the adult age group are a matter of great concern.


1970 ◽  
Vol 9 (4) ◽  
pp. 204-207 ◽  
Author(s):  
Dilruba Siddiqua ◽  
Shamim Ara ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Rukshana Ahmed ◽  
Ara Parven Hosne

Objective: A cross-sectional descriptive type of study was designed to find out the difference in weight of the right and left adrenal glands of Bangladeshi people in relation to age and to compare with the previous studies. Materials & Methods: The study was done in the Department of Anatomy, Dhaka Medical College, Dhaka from July 2008 to June 2009 and performed on 140 post mortem human adrenal glands collected from 70 unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into four age-groups including group A (11-20 years), group B (21-30 years), group C (31-40 years) & group D (41-60 years) and the weight of the adrenal glands were measured and recorded. Results: There was no difference found in weight in between the right and the left adrenal glands in any age group. For the right adrenal gland, the differences in weight between group A & group B and group A & group D were statistically significant (p<0.05). For the left adrenal gland, the differences in weight between group A & group D and group C & group D were statistically significant (p<0.05). Key words: Adrenal gland; weight of adrenal gland. DOI: 10.3329/bjms.v9i4.6686Bangladesh Journal of Medical Science Vol.09 No.4 July 2010 pp.204-207


2018 ◽  
Vol 8 (2) ◽  
pp. 23-25
Author(s):  
Hasna Hena ◽  
Shamim Ara ◽  
Hosna Ara Perven ◽  
Dilruba Siddiqua ◽  
Fatema Johora ◽  
...  

Context: Problems with the fallopian tubes can lead to infertility. Disease can be defined and measured only in terms of deviation from normal structure. Detailed morphological and histological knowledge is essential for the diagnosis and management of fallopian tube disease. Objectives: To identify the outer diameter of the infundibulum and its changes with advancing age. Study Design: Cross sectional descriptive type of study. Period and place: Department of anatomy, Dhaka Medical College from July 2008 to June 2009. Materials: Present study was performed on post mortem fallopian tubes of 60 Bangladeshi female. Among them lowest age was 12 years and highest age was 50 years. Methods: Samples were divided into three differential age groups: Group A (10-13 years), Group B (14-45 years), Group C (46-50 years). All samples were studied morphologically and histologically. Results: The mean outer diameter of the infundibulum of the right and left fallopian tubes ranged from 0.80±0.01 to 1.03±0.22 mm. The difference between all the groups were statistically significant (p < 0.001). Conclusion: There was change in outer diameter of the infundibulum of fallopian tubes of left and right in relation to age. Update Dent. Coll. j: 2018; 8 (2): 23-25


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