scholarly journals Ocular Biometry among primary angle closure

2018 ◽  
Vol 8 (1) ◽  
pp. 5-9
Author(s):  
Dakki Sherpa
Keyword(s):  
Risk Factor ◽  
Sampling Technique ◽  
Normal Subjects ◽  
Angle Closure ◽  
Control Group ◽  
Cross Sectional ◽  
Primary Angle Closure ◽  
Ocular Biometry ◽  
Lens Diameter ◽  
The Mean

Objective: To determine ocular biometry of primary angle closure. Materials and methods: A cross-sectional compara­tive study was carried out in Nepal Eye Hospital including thirty-six eyes of 29 diagnosed cases of primary angle closure and 44 eyes of 22 normal subjects selected by convenience sampling technique. A complete ocular examination of all the subjects was carried out. AL, ACD and LD measurement was done using ultrasound A scan. Result: Out of 80 eyes, there were 36 eyes of 29 diagnosed primary angle closure subjects and 44 eyes of 22 normal subjects. The mean age of primary angle closure patients were 61. 65+/- 10.44. The mean AL of PAC was 22.15mm +/-0.76. The mean AL of control group was 22.98 mm with SD of 0.63. The mean ACD of PAC patients were 2.85mm and SD of 0.46 and the mean ACD of control group was 3.59 with SD of .40. The mean lens diameter of PAC group was 4.57 mm +/- 0.58 and the mean LD of control group was 4.43mm +/- 0.54. The Sig (2-tailed) test showed: Age: 0.268, AL: 0.001, ACD: 0.000 and LD: 0.466. Conclusion: This study reveals that short AL and shallow ACD is a strong risk factor of primary angle closure. Though LD more than 4.5 mm is a risk factor of primary angle closure it is not statistically significant.

scholarly journals Association between axial length of the eye and primary angle closure glaucoma

1970 ◽  
Vol 6 (3) ◽  
pp. 361-363 ◽  
Author(s):  
D Sherpa ◽  
BP Badhu
Keyword(s):  
Risk Factor ◽  
Axial Length ◽  
Simple Random Sampling ◽  
Normal Subjects ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Control Group ◽  
Cross Sectional ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma

Background: Angle closure glaucoma is emerging as a leading cause of blindness in Asia. Objective: To compare the ocular axial length of normal individuals and the subjects with primary angle closure glaucoma. This study has been conducted to determine axial length of eye as a risk factor of primary angle closure glaucoma. Materials and Methods: A cross-sectional comparative study was carried out in Mechi Eye Care Centre, Jhapa, Nepal including forty eyes of 20 diagnosed cases of primary angle closure glaucoma (40 eyes) and 40 eyes of 20 normal subjects selected by simple random sampling. A complete ocular examination of all the subjects was carried out. Axial length measurement was done using ultrasound A scan. Results: Out of 80 eyes, there were 40 eyes of 20 diagnosed primary angle closure subjects and 40 eyes of 20 normal subjects. The mean axial length and standard deviation of primary angle closure glaucoma were 21.93 ± 1.16 mm (95% CI = 21.41 - 22.45) and those of control group were 23.01 ± 0.49 (95% CI = 22.79 - 23.23). The axial length of less than 23 mm was found as a risk factor for angle closure glaucoma (Relative risk =3.40; p = 0.0032). Conclusion: This study showed that patients with the axial length of less than 23 mm are at risk to develop primary angle closure glaucoma. This result can be confirmed by doing population based study in a larger sample size. Keywords: Axial length, Primary angle closure glaucoma, Nepal doi: 10.3126/kumj.v6i3.1712 Kathmandu University Medical Journal (2008), Vol. 6, No. 3, Issue 23, 361-363

scholarly journals Evaluation of spontaneous retinal venous pulsation in primary open-angle and primary angle-closure glaucoma patients

2020 ◽  
Vol 2 (1) ◽  
pp. 27-41
Author(s):  
Sylves Patrick ◽  
Chan Hui Tze ◽  
Rasdi Abdul Rashid ◽  
Liza Sharmini Ahmad Tajudin
Keyword(s):  
Cross Sectional Study ◽  
Angle Closure ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Venous Pulsation ◽  
Primary Glaucoma

Introduction: Spontaneous retinal venous pulsation (SRVP) is a rhythmic variation in the calibre of one or more retinal veins. The incidence of SRVP was reduced in glaucoma patients. It was also reduced in people with raised intracranial pressure compared to a healthy population. Purpose: The main objective was to report the frequency and rate of SRVP in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) patients and to associate these with the severity of glaucoma in Malay patients. Design of study: A comparative cross-sectional study. Materials and methods: A comparative cross-sectional study involving primary glaucoma patients attending the eye clinic at Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia, was performed between December 2015 and June 2017. The main outcomes measured were the presence and rate of SRVP using a confocalscanning laser ophthalmoscope (Spectralis High-Resolution Optical Coherence Tomography Angiography, Heidelberg Engineering GmbH, Heidelberg, Germany). In the presence of SRVP, the rate of SRVP in one minute was counted manually based on the real-time fundus movie recorded using the confocal scanning laser ophthalmoscope. Results: Thirty-eight POAG, 14 PACG, and 51 control group subjects were included. There was a significantly lower incidence of SRVP in primary glaucoma patients than in the control group (p = 0.003). The presence of SRVP was significantly lower in POAG than PACG (p = 0.04). There was no significant difference in the rate ofSRVP between primary glaucoma patients and the control group (p = 0.873) or between the POAG group and PACG group (p = 0.511). There was no association of incidence (p = 0.574) and rate (p = 0.167) of SRVP according to the severity of glaucoma. Systolic blood pressure (95% CI: 0.95–1.00, p = 0.038) and retinal nervefibre layer thickness (95% CI: 1.01–1.09, p = 0.008) showed a significant association with the presence of SRVP. Conclusions: SRVP is a potential predictive factor for detection of primary glaucoma. The role of SRVP in the severity of glaucoma is still unclear. The role of SRVP in PACG patients warrants further studies in the future.

scholarly journals To measure angle of anterior chamber using Topcon SD-OCT: A new technique

2021 ◽  
Vol 7 (3) ◽  
pp. 537-540
Author(s):  
Nida Khan ◽  
Prakash Agarwal ◽  
Saroj Gupta ◽  
Khalid Khan
Keyword(s):  
Anterior Chamber ◽  
Care Center ◽  
Normal Subjects ◽  
Acute Angle ◽  
Angle Closure ◽  
Cross Sectional ◽  
Health Care Center ◽  
Temporal Quadrant ◽  
The Mean ◽  
Sd Oct

The proposed new method of measuring angle of anterior chamber is an effective method of measuring the angles. Identification of narrow anterior chamber angle is important for glaucoma screening and prophylactic treatment prevents acute angle closure glaucoma event.Aim of this study wasto measure the angle of anterior chamber using Topcon spectral domain optical coherence tomography (SD OCT).In this cross-sectional study 120 normal subjects above the age of 40 years were enrolled. The study was done at the tertiary health care center of central Indian. All volunteers had visual acuity of at least 6/9 with no ocular diseases. Using OCT the angle opening distance (AOD-500), trabecular–iris angle (TIA) and trabecular-iris space area (TISA-500) were measured. In this study the mean AOD was 0.430 µm in nasal and 0.433 µm in temporal quadrant. The mean TISA in nasal was 0.405 µm and temporal quadrant was 0.408 µm. While the mean trabecular iris angle (TIA) was 26.9° in nasal and 26.01° in temporal quadrant. The study proved that the proposed method of measuring AOD, TISA, TIA is the effective method as the Topcon-2000 OCT does not have any inbuilt software like that of other ASOCT machines.

scholarly journals Accuracy of the Corvis Biomechanical Index in Keratoconus Screening

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Fazle Hanan ◽  
Zulfiqar Ali ◽  
Muhammad Naeem
Keyword(s):  
Predictive Value ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Clinical Feature ◽  
Control Group ◽  
Cross Sectional ◽  
Specificity And Sensitivity ◽  
Cross Linkage ◽  
The Mean ◽  
Normal Controls

Purpose:  To evaluate the accuracy of the Corvis Biomechanical Index (CBI) in screening of patients with Keratoconus. Study Design:  Cross sectional study. Place and Duration of Study:  Amanat Eye Hospital Peshawar from July 2018 to June 2019. Material and Methods:  One thousand eyes were included in this study. Patients who came for keratorefractive laser procedure or collagen cross linkage were included in the study by convenient sampling technique. Six hundred and eleven patients had early Keratoconus and 389 were normal controls. Control group included those individuals who had visual acuity of 6/6 with no clinical feature of Keratoconus and normal TBI. All individuals included in the study underwent a thorough ocular examination, CBI and TBI tests. SPSS version 23 was used for statistical analysis of collected data. Results: The mean CBI value was 0.3186 ± 0.407 standard deviation (SD), the standard error (SE) of the mean was 0.0129 with a 95% confidence interval (CI) of 0.293 to 0.343. The minimum CBI value was 0.00 and the maximum value was 1.00. The mean Tomographic Biomechanical Index (TBI) value was 0.465 ± 0.392 SD, SE was 0.124 with a 95% CI of 0.222 to 0.708. The range of TBI values was 0.00 to 1.00. For CBI, sensitivity was 58.2%, specificity was 100%, positive predictive value was 100%, and negative predictive value was 61.2%. Conclusion:  Although CBI is accurate in terms of specificity and sensitivity, the result should be interpreted in combination with clinical data and other topographic and tomographic parameters.

scholarly journals Vessel Density and Structural Measurements in Primary Angle-Closure Suspect Glaucoma Using Optical Coherence Tomography Angiography

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Yi Zha ◽  
Juanjuan Chen ◽  
Shuyu Liu ◽  
Jinfei Zhuang ◽  
Jianqiu Cai
Keyword(s):  
Retinal Vessel ◽  
Normal Subjects ◽  
Vessel Density ◽  
Angle Closure ◽  
Control Group ◽  
Fiber Layer ◽  
Primary Angle Closure ◽  
Rnfl Thickness ◽  
Significant Difference ◽  
Retinal Vessel Density

Purpose. To measure the macular retinal vessel density (VD) and peripapillary retinal nerve fiber layer (RNFL) in primary angle-closure suspects (PACS) by Angio-OCT to be compared with normal subjects. Methods. Primary angle-closure suspect patients and normal subjects were enrolled in this study. The demographic and clinical characteristics of all subjects, such as RNFL thickness, retinal vessel density, and ocular perfusion pressure, were compared. Results. No significant difference was found in both groups on age, sex distribution, intraocular pressure (IOP), and retinal vessel density. The PACS group exhibited significantly thicker RNFL thickness compared with the control group. The deep vessel density was negatively associated with age ( P = − 0.034 ), while IOP had negative association with ACD ( P = − 0.019 ). OPP was independently associated with RNFL ( B = 0.334 , P = 0.038 ) in the PACS group. Conclusions. OCTA showed significant thicker change on RNFL in the PACS group. Only OPP was independently associated with RNFL in the PACS group.

scholarly journals Carotid and femoral intima-media thickness in adults with sickle cell disease

2019 ◽  
Vol 6 (1) ◽  
pp. 124
Author(s):  
Nakul B. Kadam ◽  
Nikhil O. Bansal ◽  
Sourya P. Acharya ◽  
Samarth A. Shukla
Keyword(s):  
Sickle Cell ◽  
Intima Media Thickness ◽  
Common Femoral Artery ◽  
Normal Subjects ◽  
Screening Tools ◽  
Control Group ◽  
Cross Sectional ◽  
Treatment Protocols ◽  
Media Thickness ◽  
The Mean

Background: This study was conducted to evaluate Carotid Intima Media Thickness (CIMT) and Femoral Intima Media Thickness (FIMT) in adults with SCD.Methods: The present prospective cross-sectional study with control group was carried out in Department of Medicine at Acharya Vinoba Bhave rural hospital over a period of 6months from January to June 2018. A total of 100 (50 cases of SCD, 50 normal subjects) were studied. In the SCD group, 35 cases were patients regular follow up cases and 15 patients were in sickle cell crisis. CIMT of both left and right carotids were taken and the mean of the two values were recorded. The IMT was also measured in the right common femoral artery (RCFA) and left common femoral artery.Results: SCD patients in steady state had significantly decreased Hb%, increased WBC counts and platelet counts as compared to healthy controls. The mean right FIMT, left FIMT, right CIMT and left CIMT the patients with SCD with crisis were significantly higher than that of the patients without SCD (P<0.001). One way showed that there were significant differences in duration of disease in mean level of Hb%, WBC count, platelet count of the patients in the three groups (p<0.01).Conclusions: CIMT and FIMT can pick up the macrovascular involvement early and can be utilized as screening tools to predict vascular injury so that at risk individuals would be subjected to proper treatment protocols, especially hydroxyurea therapy early on.

Effect of Medialization of the Trochlear Groove and Lateralization of the Tibial Tubercle on TT-TG Distance: A Cross-sectional Study of Dysplastic and Nondysplastic Knees

2021 ◽  
pp. 036354652098781
Author(s):  
Mathias Paiva ◽  
Lars Blønd ◽  
Per Hölmich ◽  
Kristoffer Weisskirchner Barfod
Keyword(s):  
Trochlear Dysplasia ◽  
Cross Sectional Study ◽  
Magnetic Resonance Images ◽  
Tibial Tubercle ◽  
Control Group ◽  
Trochlear Groove ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean

Background: Tibial tubercle–trochlear groove (TT-TG) distance is often used as a measure of lateralization of the TT and is important for surgical planning. Purpose: To investigate if increased TT-TG distance measured on axial magnetic resonance images is due to lateralization of the TT or medialization of the TG. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A total of 84 knees (28 normal [NK], 28 with trochlear dysplasia [TD], and 28 with patellar dislocation without TD [PD]) were examined. The medial border of the posterior cruciate ligament (PCL) was chosen as the central anatomic landmark. The distance from the TT to PCL (TT-PCL) was measured to examine the lateralization of the TT. The distance from the TG to the PCL (TG-PCL) was measured to examine the medialization of the TG. Between-group differences were investigated by use of 1-way analysis of variance. Results: The mean values for TT-TG distance were 8.7 ± 3.6 mm for NK, 12.1 ± 6.0 mm for PD, and 16.7 ± 4.3 mm in the TD group ( P < .01). The mean values for TT-PCL distance were 18.5 ± 3.6 mm for NK, 18.5 ± 4.5 mm for PD, and 21.2 ± 4.2 mm in the TD group ( P = .03). The mean values for TG-PCL distance were 9.6 ± 3.0 mm for NK, 7.1 ± 3.4 mm for PD, and 5.1 ± 3.3 mm in the dysplastic group ( P < .01). Conclusion: The present results indicate that increased TT-TG distance is due to medialization of the TG and not lateralization of the TT. Knees with TD had increased TT-TG distance compared with the knees of the control group and the knees with PD. The TT-PCL distance did not differ significantly between groups, whereas the TG-PCL distance declined with increased TT-TG.

scholarly journals Emotional Bonding and Sexual Activity During COVID-19 Lockdown: A Cross-National Pilot Study

2021 ◽  
pp. 263183182110274
Author(s):  
Deblina Roy ◽  
Sujita Kumar Kar ◽  
SM Yasir Arafat ◽  
Pawan Sharma ◽  
Russell Kabir
Keyword(s):  
Online Survey ◽  
Sampling Technique ◽  
Sexual Relationships ◽  
Sexually Active ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Emotional Bonding ◽  
Significant Difference ◽  
The Mean ◽  
Study Participants

Background: The COVID-19 pandemic and lockdown measures have affected the sexuality and emotional bonding among the couple across the world. Objectives: We aimed to assess the effects of the COVID-19 pandemic and lockdown on the married people’s emotional bonding and sexual relationships in 3 south Asian counties (Bangladesh, India, and Nepal). Methods: A cross-sectional online survey was conducted among Bangladesh, India, and Nepal residents from April 3 to April 15, 2020. The survey was designed in English. The participants were selected through convenience sampling technique, the link of the online questionnaire was shared with the participants. Only participants older than 18 years and above, married, and living with their spouses were included in the study. Results: A total number of 120 respondents were included finally for analysis from the participating countries (India, Nepal, and Bangladesh). The mean age of the participants was 35.42 (±5.73) years; the majority were males under the age of 40 years and had completed postgraduation as their qualification. Among the study participants, more than half (53.8%) of the women reported being sexually active during the lockdown, whereas 41% of the men reported being sexually active. Among the sexually active participants, most women (57.7%) reported that they perceived positive emotional bonding with their partners. Nevertheless, there was no significant difference observed when compared with men. There are variations in responses. However, no significant association was identified. Conclusion: There are a few insights from the study, that is, there was no significant difference found in almost 3 countries in emotional intimacy. There had been a trend that there is improved emotional bonding with their partners, although no significant difference was observed.

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