scholarly journals ANALYSIS OF PRE-DONATION DEFERRAL REASONS AMONGST BLOOD DONORS IN VADODARA, GUJARAT.

Author(s):  
Dr. Jhalak Patel ◽  
Dr. Milind Dighe ◽  
Dr. Farzana Kothari ◽  
Dr. Rahul Rajvanshi

Background: Blood transfusion saves lives and improves health, but many patients requiring transfusion do not have timely access to safe blood. Providing safe and adequate blood should be an integral part of every country’s national health care policy and infrastructure. Aim: The main aim of the study was to analyze the reasons for pre-donation deferral amongst blood donors attending our blood bank and outdoor camp organized by our blood bank and to evaluate and categorize the reasons into temporary and permanent deferral. Materials and methods: It is a Record based Retrospective Study conducted in Department of Immunohematology and blood transfusion over a period of two years from July 2015 to July 2017. The reasons of deferral were analyzed after classification into following categories, namely, temporary- permanent deferral, in-house –camp blood donors, gender-based (male -female), and various age group categories. Results: A total of 30,022 prospective blood donors registered for blood donation out of which 2241 blood donors were deferred (7.46%) with low hemoglobin level, medication and hypertension as top three causes. The majority of deferral was seen in 18-25 years of age group which mainly comprises the youth population. The female donors were rejected eight times the male donors. Conclusion: The knowledge of the deferral incidences and their causes in a particular region helps in deciding the magnitude and the direction of the blood donor recruitment efforts. This knowl­edge also helps in calculating the eligible and the potential blood donor pool. Keywords: Blood Donors, Pre-Donation, Deferral, Temporary, Permanent.

2021 ◽  
pp. 42-43
Author(s):  
Neha Patel ◽  
Sanjay Chaudhari ◽  
Sonal Chitroda

Background: India has the second highest HIV population in the world with about 2.5-3.0 million cases. Blood transfusion saves millions of lives worldwide each year but Blood transfusion is an important mode of transmission of infections to recipients and at the same time it is also associated with large number of complications including transfusion-transmissible infections (TTIs). Aims & objective: to study the prevalence of HIVin blood donors of A.D.Gorwala Blood bank From January 2005 To December 2010. Methods: A retrospective study was conducted among blood donors through the years 2005-2010. Sera from blood donors were tested for the detection of Anti HIV by using third generation ELISA tests, strictly following the instruction of manufacturers. The donor information was collected through the donor registers from A.D. Gorwala Blood Bank. Result: From the total of 28,371 screened blood samples collected, the prevalence of HIV in blood donors in the blood bank was 0.23% in the ve consecutive years but the trend of HIV infection has decreased from 2005(0.31%) to 2010 (0.04%). The age groups18-30 has the highest prevalence and the age group 51-60 was the lowest prevalence of HIV infection. The Prevalence of HIV among male (0.18%) was higher than in female donors (0.05%). The trend of HIVinfection was decreasing for both male and female blood donors. Conclusion: The analysis of HIV seroprevalence among blood donors through the year 2005- 2010 showed a signicantly decreasing trend, probably due to the cumulative effect of increasing awareness of HIVand improved screening system for safe blood donation.


2020 ◽  
Vol 10 (2) ◽  
pp. 373-376
Author(s):  
Farida Parvin ◽  
Daanish Arefin Biswas ◽  
Bepasha Naznin ◽  
Tamanna Afroz ◽  
Mohammad Ali ◽  
...  

Introduction: Selection of proper donor according to stringent selection criteria is the prerequisite for safe blood transfusion practice. It is widely known that a large number of blood donors are deferred for different reasons. Objective: The aim of present study is to evaluate the incidence and different reasons of blood donor deferral in atertiary care hospital. Methodology: This retrospective cross-sectional study was carried out in Transfusion Medicine and Clinical Haematology Department of BIRDEM General Hospital, Dhaka, during the period from July 2016 to June 2017.The blood donor of either sex attending the mentioned department were selected purposively and categorized into four groups according to their age for this study. Donors were selected and deferred by medical officer according to national guideline. Deferred blood donors were recorded in register book and were analyzed retrospectively. Results: In current study, 1152 blood donor (8.8%) were deferred attending for allogeneic blood donation during the study period. Out of 13082 registered blood donor 11961were male (91.43%) and 1121 were female (8.57%) and deferral rate was 2.37 times more in female. Majority of the deferred donors (55.38%) were under the age of 40 where 26.82% were in between 40-49 years and 17.8% were in the range of 50 years and above. Age range of highest deferred donors (32.20%) was between 30-39 years. The number of temporary and permanent deferral were 836 (72.57 %) and 316 (27.43%) respectively. Anaemia (33.01%), underweight (21.53%) and hypotension (17.34%) were the most common reason of temporary deferral. Chronic uncontrolled hypertension (42.4%), donors with medication (16.77%) and asthma (15.18%) was the most common cause of permanent deferral. Conclusion: The deferral rate was low and most of the deferred donors were young adult. Temporary deferred donors were higher than permanent deferred donors. The most common reasons for temporary deferral were anemia, underweight and hypotension. Permanent deferral causes were chronic uncontrolled hypertension, donors on medication for various reason and asthma. Donors should be informed with a clear message on their deferral status. It is important to determine the rate and causes of donor deferral for the safety of blood transfusion and to guide the recruitment efforts for safe blood transfusion and to avoid the permanent loss of blood donors. Northern International Medical College Journal Vol.10 (2) Jan 2019: 373-376


Author(s):  
Foluke A. Fasola

The existence and sustenance of the blood bank depends on blood donors. It is imperative that the donation experience is satisfactory for the donors. Therefore this study was carried out to determine the frequency of undesirable events experienced by the blood donor as part of donor haemovigilance. This was a retrospective descriptive study of the events that occurred amongst the blood donors of the blood bank of a tertiary institution. The blood donor incident book was reviewed for the period of six months. Negative undesirable events occurred in 2% of the donor populations, of which 45.8% could not complete the blood donation process while only 16.7% completed the blood donation process. Mild vasovagal attack occurred in 0.2% of the donor population. Undisclosed deferrable risk factors/ behaviours were identified by the phlebotomist in the bleeding room which made donors unfit for donation even though they had passed the donor screening criteria. This accounted for 20.8% of those with negative experience. Guidelines are required to identify donors that are not likely to complete donation to avoid wastage of time, blood, resources and reduce undesirable experiences.


2020 ◽  
Vol 14 (3) ◽  
pp. 1085-1092
Author(s):  
Djamalladine Mahamat Doungous ◽  
Abdelsalam Adoum Doutoum ◽  
Adawaye Chatte ◽  
Richard Laougangta Dounbe ◽  
Elysée Gondimo Gabdibe ◽  
...  

En Afrique subsaharienne, les infections transmissibles par la transfusion sanguine comme la syphilis sont très répandues, avec une prévalence pouvant atteindre 25% chez les donneurs de sang. La présente étude avait pour objectif de déterminer la prévalence de la syphilis chez les donneurs de sang au niveau de la Banque du Sang d’Abéché. Nous avons mené une étude transversale à visée descriptive, qui s’est déroulée de mai à août 2017. Les échantillons de sang des donneurs ont été testés par immunochromatographie pour la détection des anticorps anti-tréponémiques (Biomnis®). Sur 789 donneurs de sang inclus dans l’étude, la prévalence de la syphilis était de 4,9 %. Les donneurs étaient à 96,1% de sexe masculin et 3,9% de sexe féminin. Cette prévalence était plus élevée chez les sujets âgés de [21-30] ans, chez les femmes, les donneurs non scolarisés, divorcés et les domestiques/ménagères habitant la zone d’Abéché urbaine. Ces résultats montrent qu’il est nécessaire de mettre en place une politique de suivi et de prise en charge médicale des donneurs de sang atteints de la syphilis.Mots clés: Transfusion sanguine, receveurs, Treponema pallidum, don de sang.   English Title: Prevalence of syphilis in blood donors at Abéché blood bank in ChadIn sub-Saharan Africa, infections transmitted by blood transfusion such as syphilis are widespread, with prevalence up to 25% in blood donors. The purpose of this study was to determine the prevalence of syphilis in blood donors at the Blood Bank of Abéché. It was a descriptive cross-sectional study, which ran from May to August 2017. Donor blood samples were tested by immunochromatography for the detection of anti-treponemal antibodies (Biomnis®). Of the 789 blood donors included in the study, the prevalence of syphilis was 4.9%. Donors were 96.1% male and 3.9% female. This prevalence was higher in subjects aged [21-30] years, women, out-of-school, divorced and domestic / household donors living in the urban Abéché area. These results shows that it is necessary to set up a policy of monitoring and medical care of blood donors with syphilis.Keywords: Blood transfusion, recipients, Treponema pallidum, blood donation.


2015 ◽  
Vol 42 (1) ◽  
pp. 77-84
Author(s):  
Hamida Khanum ◽  
Mafruha Khanom ◽  
Hashina Banu ◽  
Farhana Muznebin ◽  
Shahela Alam ◽  
...  

Prevalence of five important blood transfusion-transmitted infectious diseases (HIV, HBV, HCV, Syphilis, and Malaria) were studied among the voluntary blood donors in Dhaka. Out of 1500 donors, positive infections was identified in 99 of cases and rest of the donors were screened negative. Male voluntary blood donor were 82% and only 18% were female. About 53.53% male infectious blood donor had HBV infection whereas, 26.26% female had HBV. The difference was significant (P < 0.05). In age group of 18-24 years, 36% of the donor had HBV infection and HCV was found positive in 04.04% of student. Among the students, HBV was positive in 44%. Only 01.01% of teacher was HIV positive. Malaria infection was positive only among the business man (01.01%). The positive cases (01.01%) with TPHA found among the students, teacher and worker and the difference was significant (P<0.05). 40.40% of the volunteer blood donors were illiterate and 24.24% donor had Master degree and 8% HSC passed.Bangladesh J. Zool. 42(1): 77-84, 2014


2021 ◽  
Vol 8 (29) ◽  
pp. 2615-2619
Author(s):  
Indu Pachampully Kumaran ◽  
Archana K.A ◽  
Meena Dharmadas ◽  
Sasikala Nadanganan ◽  
Anu Kumar B ◽  
...  

BACKGROUND Even in the presence of sufficient voluntary blood donors, the need of blood is not met yet. We wanted to evaluate the causes that hinder the smooth functioning of well-maintained blood transfusion services (BTS). METHODS This is a population based cross-sectional study conducted among blood donors from voluntary outreach blood donation camp for period of one year. Total 1536 blood donors from 32 blood donation camps were subjected to study for the sociodemographic characteristic and their knowledge of blood donation. Statistical analysis of data was done using Microsoft Excel, analysed using statistical package for social sciences (SPSS) ver.16 software. RESULTS A total of 32 blood donation camps were conducted during the study period that provided 1536 donors. In most of the camps, male donors (75 %) were more than female donors. Donors of age group of 30 to 39 years (43.9 %) were more when compared to others. Donors those who were married accounted for 79.9 %. Blood donors of Hindu religion (53 %) were more. CONCLUSIONS The main hindrance for blood donor motivation is lack of knowledge. Literacy and chance to mingle in society have a positive effect on blood donor motivation. Targeting of effective donor motivation, recruitment, and retention were attained by conducting awareness classes, seminars, workshops, and visual communication modalities. KEYWORDS World Health Organization, Altruistic Blood Donor, Blood Transfusion Services, Transfusion Transmitted Infections, Blood Components and Plasma Derivatives, Director General of Health Services (DGHS), National Blood Transportation Council (NBTC)


Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 26-28
Author(s):  
Hamid Ehsan ◽  
Ahsan Wahab ◽  
Muhammad Ammar Shafqat ◽  
Muhammad Khawar Sana ◽  
Farhan Khalid ◽  
...  

Introduction: The blood transfusion (BT) system in Pakistan is fragmented, demand-driven, and depends on weakly regulated transfusion practices. This is primarily a big problem in smaller cities and remote rural areas. Pakistan has one of the highest hepatitis B virus (HBV) and hepatitis C virus (HCV) prevalence worldwide, estimated around 5 & 10 million cases, respectively. There is a considerable risk that transfusion-transmissible infections (TTIs) may have contributed to the current epidemic of HBV & HCV, affecting 7.4 % of the general population, and potential risk of HIV transmission in the country. In this systematic review, we aim to identify the prevalence of TTIs among the blood donor population and associated safety challenges. Method & Material: We conducted a systematic literature search to identify studies related to TTIs and transfusion safety in Pakistan from January 1, 2010, to January 31, 2020. A search was conducted using PubMed and PakMedinet.com (largest medical database of Pakistan); initial search retrieved 981 articles, 166 met the inclusion criteria, and after review by two independent reviewers, 33 articles met the final criteria for qualitative synthesis. Results: Analysis of 33 studies showed the seroprevalence of HBV of 2.04 % (0.81% to 4.22%), HCV of 2.44% (1.29 % to 10%), HIV of 0.038% (0% to 0.18%), syphilis of 1.1% (0.11-3.01%) and malaria of 0.11% (0.05-1.20). The rate of coinfections among blood donors varied from 0.0099% to 0.35 %. The highest number of coinfections were HCV & syphilis, followed by HCV & HBV infections. The rate of TTIs was dependent on the number of donors, donor types (replacement vs. voluntary), screening techniques used, number, and type of TTIs tested. There was a lack of universal screening for common TTIs. Syphilis and malaria were tested only 38 % & 46 % of all the blood donations. The studies with a high number of replacement donors (RDs) noted a high prevalence of TTIs of 2.5 % to 12 % compared to the studies with a high number of voluntary non-remunerated donations (VNRDs) reported TTIs rates of 1.57% to 6.2 %. There was a significant difference in the prevalence of HBV & HCV in VNRDs (0.48%) compared to RDs (4.15%). The rate of VNRDs was 0.10 % to 13%. The majority of blood donations were from male donors, representing more than 70 % of all donations. The female donations varied from 0.03% to 15 % in government/public blood banks than 29 % in private sector blood banks. The HBV & HCV infections and anemia were the most common causes of blood donation deferral. The 69.5 % of donors who tested positive for TTIs in a study reported previous blood donations. The educational status of donors noted to have an association with knowledge about the risk of TTIs. Odds of having limited knowledge about TTIs (OR: 4.04, CI: 1.567-10.435, p&lt;0.01) were greater if donors had a secondary level of education compared to those with tertiary education. 48 % of blood donors did not know about the risk of TTIs through blood transfusion. There was notification of only about 54.25 % of all donors, who tested positive for any TTIs. This was mainly due to a lack of standardized reporting and follow up systems. Conclusion: This systemic review shows a high prevalence of TTIs, especially HBV, HCV & syphilis in the blood donor population. There is a high dependency on RDs, with minimal use of healthy voluntary blood donation practices, inadequate screening of high-risk donors, repeated collections of the blood from RDs, poor quality of screening methods, and limited knowledge of donors about their health. There is a lack of widespread standardized testing and follow up of patients who tested positive on initial testing. Large prospective multicenter clinical trials are required for a better understanding of the TTIs by testing and creating a follow-up system for both blood donors and recipients. Disclosures Anwer: Incyte, Seattle Genetics, Acetylon Pharmaceuticals, AbbVie Pharma, Astellas Pharma, Celegene, Millennium Pharmaceuticals.:Honoraria, Research Funding, Speakers Bureau.


Author(s):  
P. K. Sehgal ◽  
Anubha Garg

Background: HCV is known for its chronicity and leads to cirrhosis in about 10 to 20 per cent of patients and may further progress to hepatocellular carcinoma (HCC). The global seroprevalence of HCV among blood donors varies from 0.4 to 19.2 per cent and the estimated risk for HCV transmission is between 0.10 to 2.33 per million units transfused. ELISA is the most commonly used initial assay for detecting HCV antibodies. The purpose of the present analysis was to monitor the seroprevalence of anti-HCV antibodies in the blood donor population in a hospital based blood bank in north India for a period of 10 years (2007-2016), and to evaluate the trends over the years.Methods: The purpose of the present analysis was to monitor the seroprevalence of anti-HCV antibodies in the blood donor population in a hospital based blood bank in north India for a period of 10 years (2007-2016), and to evaluate the trends over the years.Results: Of the total 340078, 298421 (87.75%) collections were voluntary and 41657 (12.25%) were replacement collections. A prevalence of 0.72% of hepatitis C virus infection was seen among the donors from the period 2007-2016. The trend of hepatitis C prevalence among donors has been fluctuating while ranging from 0.51% to 0.89%.Conclusions: For a safe blood service in our country, where comprehensive laboratory tests are neither possible nor pragmatic, it is best to switch over to 100% voluntary donations, as it is now established that only voluntary non-remunerated regular donation is the safest. Thus, one of our key strategies to enhance blood safety is to focus on motivating non-remunerated blood donors and phasing out even replacement donors. Since, no vaccine is presently available for immunization against HCV infection, transfusion transmitted HCV infection remains a potential threat to the safety of the blood supply.


Author(s):  
Ahmed Mohsen Al-kadassy ◽  
Abdulmalik Faisal Saleh Al-Ashiry ◽  
Hassan Abdulwahab Al-Shamahy

Infections transmitted in blood transfusions are the most significant concern associated with blood donation. The purpose of this study was to establish the current prevalence of hepatitis viruses (B and C), HIV and T.pallidium among blood donors at National Blood Transfusion and Research Center (NBTRC) Hodeida Branch, Hodeida city, Yemen. Serological markers of HBV, HCV, HIV 1, 2, T. pallidium antibodies were studied in 25446 (males) using commercially available kits, over a period of 3 years from January 2016 to April 2018 at National Blood Transfusion and Research Center (NBTRC) Hodeida Branch , Hodeida city, Yemen. Also, the prevalence of confirmed-positive test results of these infections was evaluated among different ages. The sero-prevalence of HBV and HCV, HIV, T. pallidium infections based on confirmation tests, were 0.74%, 0.19%, 0.38% and 0.18% respectively. The prevalence of HBV was significantly higher in age groups 37-46 years and 47-56 years with significant associated OR equal to 2.3 (p<0.001) and OR=2.7 (p=0.02) respectively. The prevalence of HCV was significantly higher in age groups 47-56 years with significant associated OR equal to 6.5 (p=0.003). The prevalence of T.pallidium was significantly higher in age group 37-46 years with significant associated OR equal to 3.6 (p<0.001). In conclusion: this study highlights the prevalence of HBV, HCV, HIV, and T. pallidium among different male ages. The prevalence varies from one age group to another, being the lowest among younger and very older age groups. Therefore, extensive recruitment of young donors should help ensure a long-term increase in the blood supply without jeopardizing safety.


2019 ◽  
Vol 2 (2) ◽  
pp. 27-32
Author(s):  
Hasdianah H. Rohan ◽  
Sasi Widuri ◽  
Yustisia Amalia

Blood transfusion service is a health care effort that utilizes human blood as a basic ingredient with humanitarian purposes and not for commercial purposes. Blood transfusion services as one of the health efforts in order to cure disease and health recovery desperately require the availability of blood or adequate blood components, safe, accessible and affordable by the community. Each blood transfusion unit has a responsibility to meet the availability of blood in its working area. Blood availability is highly dependent on the willingness and awareness of people to donate their blood voluntarily and regularly. To achieve this, blood transfusion units need to conduct donor recruitment activities which include socialization efforts and campaign of voluntary blood donor, donor deployment and donor preservation. The need for blood is increasing in this world where 1 patient from 7 patients who are hospitalized requires a blood transfusion. Imbalance between blood supply and blood needs is increasing in the world. Currently only in 62 countries, blood supplies of 100% are derived from voluntary blood donors and 40 other countries still depend on family darai donors and paid blood donors. From the results of location analysis and info from blood transfusion Unit RS, Dr. Setomo, Surabaya PMI about the problems of lack of blood stocks at a certain moment, then make us perform a lack of public awareness about the blood Donor This, thereby giving our infiration to give intervention, counseling, convey that being a blood Donor can increase the stamina and occurrence of new erythrocytes, which can facilitate blood circulation and make the body healthier. Plan, create a community Web Site that is interested in becoming a voluntary blood Donor, so that the community is moved to become a voluntary blood Donor, of course not be separated must fulfill the requirements that the blood donation is worthy as Blood and healthy Donor, appropriate Perturan.  Install Bener on a specific place, make a bag, T-shirt, key toy, a zipper box, and other knacks that can be used as the community Logo voluntary blood donor, in hopes of increasing the necessary blood stocks society.  From the new results we perform to attract voluntary blood donors. Through the appeal to come to the counseling and to share Leaflet only at this early stage, there have been obtained result of increased blood stock from the results of voluntary blood donation after Community service.  Obtained significant results, where there is an increase in the amount of blood in PMI, after the implementation of blood donation. There is an increase in blood stocks at that time as much as 40-50%, from the results of community devotion.


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