scholarly journals Study on Corticosteroids use Pattern in Dermatological Practice and Investigating Adverse Effect of Corticosteroids Including its Associated Factors

2017 ◽  
Vol 13 (3) ◽  
pp. 261-267
Author(s):  
S. Shakya Shrestha ◽  
M. Bhandari ◽  
R. Shrestha ◽  
S.R. Thapa ◽  
A. Karki ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Adverse Effects ◽  
Tertiary Care ◽  
Common Adverse Effect ◽  
Cross Sectional Study ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional ◽  
Dermatology Department ◽  
Use Pattern

Background Corticosteroids are highly effective drugs with anti-inflammatory and immunosuppressive properties. Due to this, they have become a mainstay of pharmacotherapy in dermatology. However, improper and long term uses are associated with a number of serious adverse effects.Objective To investigate the corticosteroids use pattern, adverse effects and various factors associated with adverse effects in dermatological practice.Method A cross-sectional study was conducted in a dermatology department of tertiary care hospital. All patients using at least one corticosteroids, either topically or systemically or the combination were included in this study. Informed consent was taken from the patients and interviewed using structured questionnaire. Statistical analysis was performed by using SPSS 20. p-value < 0.05 was considered as statistically significant.Result Among the 60 participants under this study, 81.67% of them were females. The mean (±SD) age of the patients was 31.03 years (±15.0). A majority (58.30%) of the patients was prescribed with topical corticosteroids with low potency (25%). Most of them had used corticosteroids for urticaria. Adverse effects were reported by 33.30% of the patients. The most common adverse effect reported was the shedding of skin. Adverse effects was significantly associated with gender; use of systemic corticosteroids; regular use of corticosteroids; discontinuation of dose abruptly; and missed dose. However, there was no significant association between adverse effects and the duration of use of corticosteroids.Conclusion In conclusion, the present study suggested that the proper counselling and clear instruction regarding the use of corticosteroid should be provided to the patients for avoiding the abrupt discontinuation of the prescribed medication leading to treatment failure.

Increased frequency of fibromyalgia among patients with chronic pain presenting to internal medicine clinics of a tertiary care hospital: a cross sectional study

2022 ◽  
Vol 71 (12) ◽  
Author(s):  
Sana Javed ◽  
Muhammad Zaid ◽  
Sumera Imran ◽  
Ayesha Hai ◽  
Muhammad Junaid Patel
Keyword(s):  
Internal Medicine ◽  
Tertiary Care ◽  
Chronic Fatigue ◽  
Cross Sectional Study ◽  
National Language ◽  
P Value ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio

Objective: To estimate the frequency of patients with fibromyalgia (by using the 2010 Modified Criteria for Fibromyalgia by American College of Rheumatology ( ACR ) presenting to Internal Medicine clinics  Methods: A cross-sectional study conducted in the department of Internal Medicine, the Indus Hospital, khi, Pakistan between December 2016 and March 2018. Patients who visited internal medicine clinics, met the selection criteria, were included in the study. After taking informed consent patients were assessed for fibromyalgia according to the new 2010 Fibromyalgia Diagnostic criteria questionnaire. The patients were asked the questions in the national language, Urdu. Data analyzed using SPSS version 21. P value of < 0.05 was considered significant. Results: Of the 267 patients presenting to the internal medicine clinics and consenting for participating in the study 149 (55.80%) met at least one of the 2010 Fibromyalgia Criteria. The prevalence of fibromyalgia as estimated in this study was 56% with no difference in gender. Mean age of patients with fibromyalgia was 42.3 ± 14.6 and patients without fibromyalgia was 38.9 ± 13.7 which was statistically significant (p-value = 0.05, 10% level of significance). Of the 267 patient 197 (73.8%) were female and 70 (26.2%) were males, a male to female ratio of 1:2.81.  Conclusion: All patients with generalized pain should be evaluated for fibromyalgia and a diagnosis made to reduce the cost of further referrals and investigations and delay in the management of this debilitating disorder. Keywords: Fibromyalgia, Chronic fatigue, Generalized Pain  

scholarly journals KNOWLEDGE OF DENTAL PROFESSIONALS REGARDING TOOTH RESTORABILITY AT A PUBLIC SECTOR TERTIARY CARE HOSPITAL OF KARACHI, PAKISTAN

2019 ◽  
Vol 9 (2) ◽  
pp. 69-72
Author(s):  
Zulfiqar Ali Shaikh ◽  
Afifa Yaseen ◽  
Amna Yaseen ◽  
Subhana Akber
Keyword(s):  
Tertiary Care ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional ◽  
Adequate Knowledge ◽  
Inadequate Knowledge ◽  
Pain Symptoms ◽  
Dental Professionals

Background: Panoptic knowledge of dental professionals is required to provide care for patients with any dental problem which ranges from screening, emergency care or referral to alleviation of pain symptoms. Ideally to provide dental care, dental practice should be based on current clinical concepts originating from evidence-based dentistry which clearly demarcates a level between a tooth that is able to be restored so that intervention is done on it for esthetic and functional stability, or ready for extraction. Dental professionals' knowledge regarding tooth restorability is very crucial in restorative and preventive dentistry. The aim of this study was to assess the knowledge of dental professionals regarding tooth restorability. Methods: Knowledge regarding tooth restorability of dental professionals of Dow University of Health Sciences was assessed through a multi centered cross sectional study. A sample size of 140 participants was calculated using through open Epi version 3, and a convenient non-probability sampling technique was used. The study was conducted in May-June, 2018. An informed consent prior to the study was taken. The dental professionals were evaluated through a self- administered, structured questionnaire in English. The SPSS-23 was used to obtain results. The knowledge of the students was graded as adequate if >12 and inadequate if<12. Results: Out of 140 study participants, 113 (81%) dental professionals had significantly adequate knowledge (p-value <0.05); while 27 (19%) had inadequate knowledge. Among the respondents, 56% said that the traumatic dental injury must be treated by dentist whereas the others considered it to be treated by private doctor or by nearest hospital casualty. Conclusion: The knowledge of dental professionals working at teaching institutes is adequate; and as per their knowledge they might be taking right decisions regarding tooth restorability.

scholarly journals Frequency of infantile colic in neonates presenting At Tertiary Care Hospital.

2020 ◽  
Vol 27 (11) ◽  
pp. 2357-2362
Author(s):  
Anwar Muhammad ◽  
Muhammad Asghar Ali ◽  
Ali Hammad
Keyword(s):  
Gestational Age ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
P Value ◽  
Care Hospital ◽  
Infantile Colic ◽  
Cross Sectional ◽  
Alternative Measures ◽  
Hospital Study

Objectives: To determine the frequency of infantile colic in neonates presenting at tertiary care hospital. Study Design: Cross Sectional Study. Setting: Department of Neonatology, Civil Hospital, Bahawalpur. Period: From January 2018 to August 2018. Material & Methods: Total 467 neonates either male or female were selected for this study. Total 467 neonates with complaints of crying and fussing either male or female were selected for this study and infantile colic was assessed in selected neonates by using Wessel criteria. Results: Total 467 neonates were selected for this study.  Mean age of the neonates was 24.94 ± 2.39 months, mean gestational age and mean weight was 39.42 ± 1.22 weeks and 3.27 ± 0.62g respectively.   Infantile colic was found in 322 (69%) neonates.  Infantile colic was found in 61 (33.33%) neonates, 136 (94.44%) neonates, 75 (87.21%) neonates and 50 (92.59%) neonates respectively.  Statistically significant association between infantile colic and type of feeding with p value 0.000.  Infantile colic was found in 147 (84.97%), 95 (67.86), 62 (49.21%) and 18 (64.29%) neonates respectively in 37 weeks, 38 weeks, 39 weeks and 40 weeks gestational age group.  Statistically insignificant association between infantile colic and gestational age was noted with p value 0.000. Conclusion: Results of present study showed higher rate of colic in infants.  Development of colic was highly associated with gestational age, birth weight and type of feeding.  There is no effective medical treatment (like anti-colic and herbal drugs) but alternative measures may relieve or prevent further colic attacks.

scholarly journals POSTPARTUM HEALTH-RELATED QUALITY OF LIFE AMONG MOTHERS: AN ANALYTICAL CROSS-SECTIONAL STUDY IN A TERTIARY CARE HOSPITAL OF RAWALPINDI

2021 ◽  
Vol 71 (2) ◽  
pp. 629-33
Author(s):  
Nadia Ramzan ◽  
Samreen Misbah ◽  
Shehla Baqai ◽  
Syed Fawad Mashhadi ◽  
Imtenan Sharif ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
P Value ◽  
Care Hospital ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

Objective: The study was conducted to assess the maternal health related quality of life and its affecting factors in postpartum period. Study Design: Analytical cross-sectional study. Place and Duration of Study: The study was done in a tertiary care hospital, Rawalpindi, from Mar to Jun 2019.Methodology: By using non-probability purposive sampling technique, sample of 268 women in post-partum period were interviewed. A validated short form-36 (SF-36) Questionnaire was administered to women aged 15-49 years, who had spontaneous vaginal delivery or cesarean section, and were within six weeks up to six months of postpartum period. Data was analyzed by using SPSS-22. A p-value of ≤0.05 was taken as significant. Results: Highest median scores were reported in physical functioning 75 (55, 90) and social functioning 75 (75, 62). Lowest median scores were reported in energy fatigue 37 (31, 50) body pain 45 (22, 62) and general health 45 (30, 60). Health-related quality of life scores showed significant difference (p-value <0.05) among subgroups of time since delivery, mode of delivery, education of women, husband’s education and antenatal visits. Conclusion: The study showed that health related quality of life score of postpartum women was moderately affected; where in physical and social functioning domains strongly contributes in better quality of life. Energy/fatigue, body pain and general health are the weakest domains adversely affecting quality of life. Women in subacute postpartum phase, with cesarean section, lower educational status and less than 04 antenatal visits are associated with poorer HRQOL.

scholarly journals Study of Parasitic Infection in Immunosuppressive Patients and its Association with the Socio-demographic Status

2021 ◽  
Author(s):  
J Lakhani Sucheta ◽  
Dhruba Hari Chandi ◽  
J Lakhani Som
Keyword(s):  
Entamoeba Histolytica ◽  
Close Contact ◽  
Demographic Data ◽  
Tertiary Care ◽  
Parasitic Infection ◽  
Cross Sectional Study ◽  
Parasitic Infections ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional

Introduction: In developing countries, immunosuppressive patients are at greater risk of parasitic infection which may cause morbidity and mortality. Socio-economic and environmental factors including lack of health hygiene in close contact with infected reservoir animal which plays an important role. Aim: To determine the prevalence of parasitic infections and their association with socio-demographic status. Materials and Methods: This was a cross-sectional study which was carried out at tertiary care hospital located in Central East India. Total 120 stool samples were collected from the immunosuppressive patients and were processed using direct wet mount preparation with saline and Lugol, formalin-ether concentration and Modified Ziehl-Neelsen stain. Different socio-demographic parameters were recorded. Statistical analysis was done using Graph Pad Prism version 8 Chi-square test. The p-value ≤0.05 was considered as statistically significant Results: Out of total 120 patients, 20 (16.7%) were found to be infected. Majority of the population were males (66.7%). Among the total positive samples, 75% (15) showed the presence of Protozoa in which 10 samples had Entamoeba histolytica. The presence of Helminths was found in 25% (5), in which three samples showed Ascaris lumbricoides and two had Taenia species (10%). Conclusion: The prevalence of parasitic infection among immunosuppressive patients in the present study was 16.7%. Entamoeba histolytica was the most commonly observed parasite. There was no significant association between prevalence of parasitic infections and socio-demographic data variables.

Neurological manifestations in children with dengue fever: an Indian perspective

2016 ◽  
Vol 47 (2) ◽  
pp. 145-149 ◽  
Author(s):  
Archan Sil ◽  
Tamoghna Biswas ◽  
Moumita Samanta ◽  
Mithun Chandra Konar ◽  
Arun Kumar De ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Transverse Myelitis ◽  
Acute Disseminated Encephalomyelitis ◽  
Cross Sectional Study ◽  
Neurological Involvement ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional ◽  
Motor Weakness ◽  
One Year

Ours was a descriptive observational cross-sectional study carried out in a tertiary care hospital in eastern India over a period of one year to study the profile of neurological involvement in paediatric dengue patients. Of 71 laboratory-confirmed cases, 20 (28.17%) had neurological involvement. Common forms observed were acute encephalopathy (40%), encephalitis (30%), pure motor weakness (15%), transverse myelitis (5%), acute disseminated encephalomyelitis (5%) and Guillain–Barré syndrome (5%). The dengue IgM antibody could be detected in the cerebrospinal fluid of only two patients with encephalitis. Neurological involvement was present in all four patients who died during the study period (two-tailed P value = 0.005).

Mucocutaneous manifestations of Chikungunya fever, an experience of tertiary care hospital

2020 ◽  
pp. 1-13
Author(s):  
Sana Kaleem ◽  
Rabia Ghafoor ◽  
Sidra Khan ◽  
Admin
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
P Value ◽  
Care Hospital ◽  
Inform Consent ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Chikungunya Fever ◽  
Oral Ulcers

Abstract Objectives: 1. To determine the different frequencies of mucocutaneous manifestations of Chikungunya Fever in a Tertiary care hospital. To determine the associations of positive Chikungunya Fever serology with its mucocuatneous manifestations. Methodology: It was observational cross-sectional study conducted in Department of Dermatology of Jinnah Postgraduate Medical Centre from 15th May 2018 to 15th January 2019. After getting approval from Institutional Review Board, 67 patients were recruited in study by purposive sampling who presented with early and late manifestations of Chikungunya Fever (CF). Different cutaneous manifestations were confirmed by consultant Dermatologist. Photographs were taken after the inform consent of patients. Data was analysed by SPSS 23 and P value was taken significant with < 0.05. Result: The mean age of patients was 30.24±7.89 years. Females and males were 45 (68%) and 20 (31%) respectively. Hyperpigmentation were noted as most frequent finding in 31 (46%), maculopapular rashes ,oral ulcers in 17 (25%), and diffuse hair fall in 14(20%) .Findings like lichenoid eruption in 11 (16%), chick sign in 5 (8%), and erythema of Pinna in 4 (6%) were also recorded. While hair falls, exacerbation of pre-existing dermatoses like psoriasis and acne form eruption were also seen rarely.  There was no significant association was found between clinically suspected cases and serology positive patients of CF. Conclusion: CF presented with important and unusual mucocutaneous findings which are important to diagnose as they help in differentiating it from other viral diseases. We observed that some finding remain long standing and presented months

scholarly journals Bacterial Contamination of Stethoscope in a Tertiary Care Hospital

2018 ◽  
Vol 30 (2) ◽  
pp. 1-6
Author(s):  
Md Azizul Haque ◽  
Khandaker Md Faisal Alam ◽  
Laila Shamima Sharmin ◽  
Atike Mahmud ◽  
MM Washee Parvez ◽  
...  
Keyword(s):  
Bacterial Contamination ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Medical College Hospital ◽  
P Value ◽  
Care Hospital ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College

Bacterial contamination of stethoscope and its role in transmission of nosocomial infection is little known among the healthcare workers of Bangladesh. The objectives of our study is to evaluate stethoscope handling and cleaning practices, to find out the bacterial agents contaminating the stethoscopes, to determine the antibiotic sensitivity patterns of bacterial isolates from stethoscopes, and to evaluate the relationship between stethoscope cleaning practices with contamination of stethoscope in Rajshahi Medical College Hospital. This observational cross sectional study was carried out in Rajshahi Medical College Hospital during March, 2017. One hundred doctors working in different departments of RMCH were chosen randomly and were asked to fill up a self-explanatory simple questionnaire. Samples from100 stethoscopes were obtained after swabbing the diaphragm and the bell of the stethoscope with a sterile swab moistened with saline. These swabs were immediately streaked onto blood agar, Mcconkey agar and chocholate agar following the standard protocol. Out of 100 stethoscopes examined for bacterial contamination, 19 stethoscopes (19%) were found to be contaminated. The organisms isolated were MRSA, pseudomonas aeruginosa, and E. coli. Among the 19 participants with bacterial contamination of stethoscope, 6 doctors (31.6%) said they used to clean their stethoscope at least occasionally and 13 doctors (68.4%) had never cleaned their stethoscope. This difference was found to be statistically significant (p value <0.005).TAJ 2017; 30(2): 1-6

scholarly journals Knowledge about obstetric danger signs among pregnant women attending antenatal clinic in a tertiary care hospital of Delhi: a cross sectional study

2019 ◽  
Vol 8 (9) ◽  
pp. 3738
Author(s):  
Ashok Kumar ◽  
Geeta Yadav ◽  
Vijay Zutshi ◽  
Suman Bodat
Keyword(s):  
Pregnant Women ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
P Value ◽  
Care Hospital ◽  
Sectional Study ◽  
Danger Sign ◽  
Cross Sectional ◽  
Obstetric Danger Signs ◽  
Danger Signs

Background: According to UNICEF, globally 800 million women die due to preventable causes related to pregnancy and childbirth; 20% of which occur in India. It is therefore imperative to understand the level of knowledge about danger signs among pregnant women to augment timely redressal of preventive obstetric causes of mortality.Methods: A hospital based, cross sectional study was conducted at the ANC Clinic in Safdarjung Hospital, New Delhi from 2nd July to 27th July 2018. Convenient sampling was used to identify and interview 354 pregnant women, using a semi structured questionnaire. Data was entered and analysed with SPSSv21. Results were presented as frequencies and proportions. Chi square was used to test for association between qualitative variables, and p-value less than 0.05 was considered significant.Results: 48.3%, 35.6%, and 40.1% of pregnant women had knowledge about danger signs during pregnancy, labour and postpartum respectively. Majority of the women had knowledge about abdominal pain (58.4%) and severe fatigue (80.7%) as danger signs of pregnancy, while bleeding (82.5%) was the most common response as danger sign of labour. More than half had knowledge about heavy bleeding (59.9%) as danger sign of postpartum. The women lacked awareness about Convulsions (92.9%) as danger signs of pregnancy and labour, as well as smelly vaginal discharge (79.6%) in postpartum.Conclusions: Knowledge of obstetric danger signs among pregnant women is still lower. It needs further awareness as it can help in early diagnosis and referral of patients thus reducing maternal mortality and morbidity.

scholarly journals A study of serum C peptide levels in newly detected diabetic patients in tertiary care hospital

2021 ◽  
Vol 8 (5) ◽  
pp. 679
Author(s):  
Balakrishna Teli ◽  
Prabhu S. ◽  
Sneha Biradar
Keyword(s):  
Tertiary Care ◽  
Cross Sectional Study ◽  
Study Data ◽  
P Value ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Cross Sectional ◽  
C Peptide ◽  
Medical College ◽  
Endogenous Insulin

Background: Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycemia. The deficiency of C-peptide in type 1 DM or its excess in type 2 DM leads to the development of disorders which includes the cardiovascular, nervous, excretory and other systems. The present study is done to assess the serum C-peptide levels in newly detected diabetic patients and its significance in classification of diabetes and deciding about management.Methods: This cross sectional study was conducted within the hospitals attached to Bangalore medical college and research institute. 65 newly detected diabetes patients who gave consent for study and satisfy the inclusion criteria were included in the study. Data was collected using semi structured questionnaire, clinical examination and relevant investigations. Statistical analysis was performed using SPSS software. A p value of <0.05 was considered significant.Results: C-peptide levels showed that 34 (52.3%) subjects had C-peptide levels >2 followed by 10 (15.4%) subjects having 0.1 to 0.6, 9 (13.8%) subjects having 1 to 2, 6 (9.2%) subjects each having 0.6 to 1 and <0.1.Conclusions: Serum C-peptide levels are useful as an index of endogenous insulin production. Low C-peptide levels need insulin treatment due to poor insulin reserve. Majority of the subjects, who had low serum C-peptide levels also had low BMI suggesting a positive correlation between C-peptide levels and BMI.

Sign in / Sign up

Export Citation Format

Share Document