scholarly journals Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control Study

2019 ◽  
Vol 17 (1) ◽  
pp. 17-21
Author(s):  
Annu Ranjit ◽  
Sudharshan Lal Rajbhandari ◽  
Narayan Gautam ◽  
Yogesh Poudyal
Keyword(s):  
Case Control Study ◽  
Strong Association ◽  
Serum Zinc ◽  
Zinc Level ◽  
Case Control ◽  
Medical Sciences ◽  
Serum Zinc Level ◽  
Significant Difference ◽  
Common Skin ◽  
Control Study

Introduction: Cutaneous viral warts are one of the common skin disorders in general population which can affect any age group and any gender in any country and pose a significant health problem. A possible association with zinc has been suggested in previous studies. Zinc is known to be required for efficient functioning of immune system. Objective: To find out the association between serum zinc level and cutaneous viral warts.  Materials and methods: In this case-control study, total of hundred patients were enrolled. Among them 50 (males – 27, females – 23) with cutaneous viral warts were taken as cases and 50 (males – 25, females – 25) healthy individuals were taken as controls after matching the age and sex. The patients were selected from Dermatology outpatient Department of Universal College of Medical Sciences Teaching Hospital, Bhairahawa, Nepal. The serum zinc level was measured using spectrophotometry principle. Results: The mean serum zinc level in the cases and controls were 80.50±37.24 mg/dl and 104.31±25.31 mg/dl respectively. Significant difference in serum zinc level was observed between cases and controls (p=0.0001). There was a strong association between low serum zinc level and cutaneous viral warts (OR=7.37; 95% CI=1.98 – 27.31; p=0.0028). Conclusion: Serum zinc level in patients with cutaneous viral warts was significantly low as compared to the healthy controls.

scholarly journals Evaluation of Serum Zinc Concentration in Vitiligo, A Case-Control Study

2020 ◽  
Author(s):  
Ahmed Abdul-Aziz Ahmed ◽  
Hayder Saad Ahmed ◽  
Ahmed Talib Abdulqader ◽  
Wisam Suhail Najem
Keyword(s):  
Rural Area ◽  
Case Control Study ◽  
Venous Blood ◽  
Serum Zinc ◽  
Zinc Level ◽  
Case Control ◽  
P Value ◽  
Serum Zinc Level ◽  
The Mean ◽  
Control Study

AbstractBackgroundVitiligo is an acquired autoimmune pigmentary disorder characterized by ivory white patches. Zinc is proposed to have an immune modulatory, antioxidant and antiapoptotic properties in vitiligo patients. The aim of this study is to evaluate serum zinc in vitiligo patients.Patients and methodsThis is case–control study conducted from December 2019 to May 2020. The study included 50 patient with vitiligo and 50 age- and sex-matched controls. A 2 ml venous blood sample was taken from patients and controls by zinc-free syringe and was measured by atomic absorption spectrophotometry.ResultsThe mean serum zinc level was 73.14±19.32 in patients group and 85.36±14.14 in controls group (p-value=0.005). It also was 77.65±22.07 and 82.84±14.32 in male patients and controls, respectively. In female patients, it was 70.82±17.65and in female controls was 82.88±13.79(p-value=0.02). Regarding the residence, the mean serum zinc level in patients group was 70.13±21.4 in urban and 76.39±17.73 in rural area. In controls group, mean serum zinc was 83.25±14.12 and 89.11±13.77 in urban and rural area, respectively (p-value=0.003). According to the clinical patterns of vitiligo, the mean serum zinc observed was 75.32±19.64 in vitiligo vulgaris, 70.45±21.23 in acrofacial vitiligo and 68.7±17.61 in segmental vitiligo (p-value=0.68).ConclusionSerum zinc level was significantly low in patients with vitiligo but not associated with the type of vitiligo or family history of autoimmune diseases. It was even lower when vitiligo is associated with nail changes than vitiligo without any nail abnormalities.

scholarly journals Serum Zinc, Total & Free PSA, Free/Total PSA Ratio and Prostate Cancer Association: A Case Control Study

2013 ◽  
Vol 4 (1) ◽  
pp. 15-19
Author(s):  
Md Tahminur Rahman ◽  
Mahbuba Ashrafi Mumu ◽  
ATM Mowladad Choudhury ◽  
Rosy Sultana ◽  
Sonia Shirin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Prostatic Cancer ◽  
Serum Zinc ◽  
Zinc Level ◽  
Serum Zinc Level ◽  
Free Psa ◽  
Significant Difference ◽  
Total Psa ◽  
Control Study

This case case control study was undertaken to see if there is any association of serum Zinc level with histologically diagnosed prostatic cancer patients. Also to re-establish the importance of estimation of serum Prostate specific antigen PSA, (Total, Free and ratio between free and total) in prostate cancer patients. It was evident from the present study that serum Zinc level has got statistically significant difference between control and prostate cancer patients (p<0.000),. Total PSA and ratio of free and total PSA was also significantly different between control and prostatic cancer patients (p<0.04 and 0.006 respectively). However no significant difference was observed in free PSA level between this two groups (p<0.282).It was concluded from the present study that serum Zinc level could be an adjuvant laboratory test in the diagnosis of prostate cancer and can be started as a routine test in case of suspected prostatic cancer. Also total PSA level and ratio of free and total PSA not free PSA should be done and correlated for diagnosis of prostate cancer. DOI: http://dx.doi.org/10.3329/akmmcj.v4i1.13679 AKMMC J 2013: 4(1): 15-19  

Risk factors associated with subacromial pain in young athletes: A case control study

2021 ◽  
pp. 1-9
Author(s):  
Zoran Z. Sarcevic ◽  
Andreja P. Tepavcevic
Keyword(s):  
Logistic Regression ◽  
Case Control Study ◽  
Case Control ◽  
Sternoclavicular Joint ◽  
Pectoralis Major ◽  
Young Athletes ◽  
Serratus Anterior ◽  
Significant Difference ◽  
Lower Trapezius ◽  
Control Study

BACKGROUND: Subacromial pain (SAP) is a common complaint of young athletes, independently of the sport engaged. The prevalence of SAP in some sports is up to 50%. OBJECTIVE: The study was aimed to investigate some new factors possibly associated to subacromial pain in young athletes. The factors considered were the grade of tightness of the clavicular portion of the pectoralis major, dysfunction of the sternoclavicular joint, and serratus anterior and lower trapezius strength. METHODS: This case-control study included 82 young athletes 9–15 years, 41 with the symptoms of SAP and 41 controls. All participants self-reported whether they had subacromial pain. In addition, Hawkins–Kennedy Test was performed to all the participants to evaluate the subacromial pressure. Main outcome measures were the grade of tightness of the clavicular portion of the pectoralis major, dysfunction of the sternoclavicular joint, and serratus anterior and lower trapezius strength. The grade of tightness of the clavicular portion of the pectoralis major and the dysfunction of the sternoclavicular joint were measured with an inclinometer. Serratus anterior and lower trapezius strength were measured by a handheld dynamometer with external belt-fixation. The data were analyzed using t-test for independent samples, Mann-Whitney U test, contingency coefficients and a stepwise binary logistic regression. RESULTS: Significant statistical difference was observed in the grade of tightness of the clavicular portion of the pectoralis major and in the variable representing the physiological functioning of the sternoclavicular joint, between the cases and the controls. There was no significant difference in serratus anterior and lower trapezius strength between the cases and the controls. Logistic regression analysis showed that the variable representing the physiological functioning of the sternoclavicular joint and the grade of shortening of the clavicular portion of the pectoralis major were good predictors for presence of SAP. CONCLUSIONS: A strong association was determined between subacromial pain in young athletes, clavicular portion of pectoralis major tightness and the dysfunction of the sternoclavicular joint.

First-trimester fetal growth discordance and development of preeclampsia in dichorionic twin pregnancies

2015 ◽  
Vol 43 (6) ◽  
Author(s):  
Tanya Maric ◽  
Natasha Singh ◽  
Keith Duncan ◽  
Guy J. Thorpe-Beeston ◽  
Makrina D. Savvidou
Keyword(s):  
Fetal Growth ◽  
Case Control Study ◽  
Subsequent Development ◽  
First Trimester ◽  
Case Control ◽  
Retrospective Case ◽  
Crown Rump Length ◽  
Significant Difference ◽  
Twin Pregnancies ◽  
Control Study

AbstractTo investigate the relation between first-trimester fetal growth discrepancy, as assessed by crown-rump length (CRL) at 11+0 to 13+6 weeks of gestation, and subsequent development of preeclampsia (PE) in dichorionic diamniotic (DCDA) twin pregnancies. The association between inter-twin CRL and birth weight (BW) discrepancy was also investigated.This was a retrospective, case-control study of DCDA twin pregnancies. Inter-twin CRL discrepancy was calculated as 100×(larger CRL–smaller CRL)/larger CRL. BW discordance was calculated as 100×(larger BW–smaller BW)/larger BW.The study included 299 DCDA pregnancies that remained normotensive and 35 that subsequently developed PE. There was no significant difference in the inter-twin CRL discrepancy between pregnancies complicated by PE and those that were not [3.2%, interquartile range (IQR): 0.5–4.5% vs. 3.3%, IQR: 1.4–5.5%; P=0.17]. There was a positive correlation between inter-twin CRL and BW discrepancy but only in pregnancies that remained normotensive (P<0.001). In women that subsequently developed PE, there was no association between inter-twin CRL and BW discordance (P=0.54).In unselected DCDA twins, first-trimester CRL discrepancy is not different between pregnancies that subsequently develop PE and those that remain normotensive. Furthermore, in pregnancies that are complicated by PE, the association between inter-twin CRL and BW discrepancy appears to be lost.

scholarly journals The association of male infertility with telomere length: A case control study

2021 ◽  
Vol 8 (4) ◽  
pp. 325-332
Author(s):  
Kate Deepali Rajesh ◽  
Puranam Vatsalaswamy ◽  
Manvikar Purshotam Rao
Keyword(s):  
Male Infertility ◽  
Telomere Length ◽  
Real Time ◽  
Real Time Pcr ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Significant Difference ◽  
Control Study ◽  
Sperm Telomere Length

To study the relevance of sperm telomere length and infertility in men. : Our case-control study included twenty-five males in couple with sub-fertility/infertility (test group) and twenty five healthy males (control group) with proven paternity in the age group 25 to 35 years. The Absolute Sperm Telomere length (aSTL) was measured by real-time PCR. We investigated whether any significant difference in the aSTL value existed between the groups and analysed the relationship between aSTL and other sperm parameters.The mean (SE) aSTL recorded in the infertile cases was significantly shorter than for the control group being 140.60 (6.66) Kb/genome and 239.63 (12.32) Kb/genome respectively (p &#60;0.001) A weak correlation was eminent between aSTL kb/genome and the total sperm count mil/ml (rho= 0.04, p - 0.86), progressive sperm motility (rho= - 0.02, p=0.934) and sperm viability (rho= - 0.07 p=0.741) in the infertile group. The measurement of aSTL by real-time PCR is a simple and rapid method that offers further paramount information with respective to the quality of sperm. It is befitted for epidemiological studies, hence opening new perspectives in the evaluation of male infertility. Limitations - Our study was confined to men aged between 25 and 35 years. Further comparative studies are needed to explore the significance of STL and infertility in older males. Additional studies will help illumine the significance of aSTL as a prognostic biomarker in assisted reproduction.

scholarly journals Comparative study of serum zinc concentration in recurrent herpes labialis patients and healthy individuals

2020 ◽  
Author(s):  
Zahra Ranjbar ◽  
Maryam Zahed ◽  
Mohammad Ali Ranjbar ◽  
Zahra Shirmardan
Keyword(s):  
Healthy Subjects ◽  
Serum Zinc ◽  
Zinc Level ◽  
Therapeutic Effects ◽  
Herpes Labialis ◽  
Healthy Individuals ◽  
Serum Zinc Level ◽  
Significant Difference ◽  
Recurrent Herpes ◽  
History Of

Abstract Background: Recurrent herpes labialis (RHL) is one of the most common recurrent infective vesiculoulcerative lesions. Topical and systemic administration of Zinc compounds has been found to have preventive and therapeutic effects. The purpose of this article is to evaluate the serum level of zinc in patients with RHL and healthy individuals. Methods: This cross-sectional study was performed on 43 patients with the history of recurrent herpers labialis and 42 healthy subjects with no history of the lesion. Blood samples were taken and serum zinc level was measured. Chi-Square test was used to compare the qualitative relationships and to compare the quantitative relationships independent T-test was used. To observe the relationship of quantitative factors including serum zinc level, the number of relapses and recovery rates correlation test was taken. Results: The results show that serum zinc level has no significant difference in healthy subjects and patients (p> 0.05). Also, zinc level was not related to age and sex factors and frequency of relapse (P> 0.05). But surprisingly in the patients group, there was a significant relationship between zinc level and recovery period. As the serum zinc level was lower, the duration of recovery was significantly higher (p =0.009). Conclusion: The results of this study indicate that zinc deficiency is a risk factor for increasing the duration of herpes labialis lesions. Therefore, the evaluation of serum zinc level in subjects with recurrent herpes labialis and subsequent administration of zinc is recommended in such patients.

scholarly journals The Relationship between Serum Levels of Vitamin C, Uric Acid and Antioxidant Condition with Coronary Artery Diseases: a Case-Control Study

2019 ◽  
Author(s):  
Aida Torkzaban ◽  
Seyed Amir Mansour Alavi Naeini ◽  
Akbar Hassanzadeh ◽  
Mehrdad Namdari
Keyword(s):  
Uric Acid ◽  
Vitamin C ◽  
Case Control Study ◽  
Demographic Data ◽  
Systolic Pressure ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Significant Difference ◽  
Control Study

Abstract Background Coronary hearth diseases are among the main causes of death in adults. Increase of oxidative stress and defects in antioxidant defense play a major role in endothelium performance and are an effective factor in progress of atherosclerosis. Some studies have also reported different malondialdehyde and total antioxidant capacity among the atherosclerosis patients.Methods In this case-control study, 44 atherosclerosis patients referring to Shahid Madani treatment-education center were considered as the case group; while 44 healthy peoples were placed in the control group. Demographic data and anthropometric indices were measured. Food frequency questionnaire and international physical activity questionnaires were also completed. After 12 hours of fasting, 10 ml blood was sampled from the participants. Uric acid, vitamin C, TAC and MDA were also measured. The data were finally analyzed by SPSS Ver 22 software.Results A significant difference was observed between the two groups in terms of uric acid (P<0.001) and vitamin C (P<0.03). However, mean MDA and TAC showed no significant difference between the two groups. The two groups’ difference in terms of vitamin A, E and beta carotene, zinc and selenium intake was not significant. A significant difference was however detected between the two groups in terms of vitamin C (P<0.047). A significant relationship was also observed between the systolic pressure and CHD (P<0.028).Conclusion Results of this study indicated that the uric acid and vitamin C levels of atherosclerosis patients had significant increase and decrease in comparison with the healthy subjects, respectively. Mean TAC and antioxidant levels of their diets (except for vitamin C) showed no significant difference. Systolic blood pressure of the patients was significantly higher than the controls.

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