scholarly journals A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu Valley

2019 ◽  
Vol 2 (1) ◽  
pp. 145-148
Author(s):  
Prabhakar Pokhrel ◽  
Neena Rai ◽  
Rajan Pathak ◽  
Aajma Thapa ◽  
Nishchal Regmi ◽  
...  

Introduction: Alcohol is a legally allowed substance used for recreation associated with harmful health consequences both on using it and trying to quit (withdrawal phase). Many patients of alcohol dependence are brought to hospital or emergency in the withdrawal phase and require intensive treatment. It’s associated with life threatening conditions and associated with occurrences of seizures and confusion. Based on severity, it can be subtyped and managed differently. The study tries to compare and contrast the subtypes of withdrawal phases of alcohol in terms of clinical, outcome and metabolic parametersMaterials and Methods: This is a cross-sectional study of all patients diagnosed as alcohol dependence syndrome admitted over a period of two years (June 2016 to June 2018) in the psychiatric ward of KIST medical college and teaching hospital. It’s divided into two phases namely complicated and uncomplicated phase and clinical, outcome and metabolic parameters are compared and contrasted.Results: Out of 166 patients studied, 54% of the patients were diagnosed with complicated withdrawal features. Significant changes were noticed in increase duration of stay, low level of platelets and potassium and SGPT levels in a complicated group compare to the uncomplicated group. Mortality was not seen in any of the groupConclusions: Patients can be treated in-ward setting successfully and if the diagnosis is of complicated withdrawal then metabolic parameters like potassium, platelet level has to be taken into consideration. Complicated withdrawal features increase the chance of morbidity and increase the duration of stay.

Author(s):  
Arvind Visweshwar ◽  
Mohamed Hanifah ◽  
. Murugesan ◽  
. Avudaiappan ◽  
Arun Prakash

Aim: To detect the prevalence of asymptomatic neuropathy using nerve conduction study among alcohol dependence syndrome patients and to investigate the existence or not of correlation between duration, quantity of alcohol consumption and neuropathy. Study Design: Observational cross-sectional study. Place and Duration of Study: Department of General Medicine and Department of Psychiatry, Mahatma Gandhi Medical College and Research Institute, Pondicherry, affiliated to Sri Balaji Vidyapeeth (Deemed to be) University, India between February 2019 and August 2020. Methods: Alcohol dependence syndrome patients, asymptomatic for neuropathy were prospectively included and, patients who were symptomatic and had other comorbid conditions that can cause neuropathy were excluded. Patients were then submitted to nerve conduction studies. In patients who had neuropathy, duration and quantity of alcohol consumption were compared for correlation. Results: This study included 65 male patients who were mostly middle aged heavy drinkers of alcohol. 73.8% (n=48) had neuropathy. Our research showed longer the duration, larger the quantity of alcohol consumption, and higher the Cut-Annoyed-Guilty-Eye (CAGE score), more were the prevalence of neuropathy. This research also used Severity Of Alcohol Dependence Questionnaire (SAD-Q) scoring for screening alcohol dependence which showed patients with neuropathy were moderate drinkers. We did not find correlation with age of patients and neuropathy. Conclusion: This research results like correlation of prevalence of neuropathy and duration of alcohol consumption and quantity of alcohol consumption were in contrast with previous studies on alcoholic neuropathy. This research used SAD-Q scoring for dependence, future researches can throw light on usage of SAD-Q score in asymptomatic neuropathy and the correlation of neuropathy with alcohol consumption.


2021 ◽  
Vol 59 (240) ◽  
Author(s):  
Mukti Acharya

Introduction: Alcohol dependence syndrome is an important and major public health issue seen in our community and health center. It is mostly associated with different mental health problems and psychiatric co-morbidities. This study aims to find out the prevalence of depression among alcohol dependence syndrome in a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted over one year from April 15, 2020, to February 15, 2021 at a tertiary care hospital. The ethical approval was obtained from the Institutional Review Committee of Nobel Medical College (reference number: 409/2020). Convenience sampling method was used. The patients admitted for alcohol use and related problems in the Psychiatry Department, Nobel Medical College Teaching Hospital, Biratnagar were included. Data entry was done using Microsoft Excel and statistical analysis was done by using Statistical Packages of Social Sciences Version 16.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage. Results: The prevalence of depression in patients with Alcohol Dependence Syndrome was 17 (16.3%) (95% Confidence Interval= 9.20-23.39) . The patients suffering from depressive disorder male and female were 16 (94.1%) and 1 (5.8%) respectively. The participants with Alcohol Dependence Syndrome with no other comorbid psychiatric disorders were found to be 60 (57.7%). Conclusions: Psychiatric comorbidity was found to be common in alcohol dependent people among which depression was found to be most common.


2017 ◽  
Vol 5 (1) ◽  
pp. 18-21
Author(s):  
R.G. Joshi ◽  
D.R. Shakya ◽  
P.M. Shyangwa ◽  
B. Pradhan

Introduction: Women with ADS may have psychiatric comorbidites along with physical comorbidities. Societal attitudes towards women and alcohol are barriers to the detection and treatment of their alcohol related problems.Objective: To explore the magnitude of co-morbidity among women with ADS in Eastern Nepal.Method: This is a hospital based cross-sectional study of women with ADS. Those who scored two or more than two in T-ACE questionnaire were enrolled. The diagnosis was made according to ICD-10 criteria. Consultation with concerned physician was done to assess physical condition.Result: Fifty one patients with ADS were enrolled. Among them, 21.6% had no comorbidity, 52.9% had single co-morbidity (psychiatric or physical) and 25.5% had both psychiatric and physical co-morbidity. In psychiatric comorbidity, mood disorder in 35.29% was the commonest followed by nicotine use in 26.47%. Among mood disorders 83.3% had depression. In physical comorbidity, disease of gastrointestinal tract and hepatobiliary system in 50.9% was the commonest followed by hypertension in 11.5%.Conclusion: : Psychiatric as well as physical co-morbidities are common in women with ADS. The finding points to the importance of exploring comorbidities and their optimal treatment.


Author(s):  
NEERAJ J KARANDIKAR ◽  
PRITISH K RAUT ◽  
PRASAD K TAGAD

Background: Alcohol abuse is one of the major causes of death and disability globally; and a key risk factor for health, social, and economic problems in the communities. Consumption of alcohol by Indians has increased drastically due to various factors and in an unrestricted manner; and the age of initiation of drinking is progressively coming down. Objective: To determine the socio-demographic and clinical profile of the patients coming for treatment of alcohol dependence syndrome in the psychiatry department. Methods: A cross-sectional study was conducted on 50 male outpatients of alcohol dependence syndrome attending the department of psychiatry at a tertiary care hospital. Sociodemographic data and clinical details were recorded with the help of a pre-designed questionnaire. Results: Nuclear family, family history of alcoholism, unmarried status, higher educational level, unemployment, and peer pressure are the factors significantly associated with early age at first drink and age of dependence on alcohol (p < 0.05). Conclusion: Adolescents having a family history of alcoholism are a high-risk group for developing alcohol dependence and should be targeted for intervention strategies. Community based-longitudinal studies are needed to understand multiple factors influencing alcohol use and recommend targeted preventive measures. Keywords: Alcohol, Alcohol dependence syndrome, Peer pressure, Intoxication, Socio-demographic factors


2019 ◽  
pp. 48-51
Author(s):  
Challuri Prashanth ◽  
B. Sowmya Grace

Background :Alcohol is a ordinary commodity, used since time immemorial. Psychiatric co morbidities have a high prevalence among patients of alcohol dependence and often pose challenges in their diagnosis and treatment and are found to be a major contributor to relapses. They raise a challenging question of how to provide the best integrated treatment to address both. Aim : To study the socio demographic profile and psychiatric co morbidity in patients of alcohol dependence syndrome. Objectives: 1. To study the socio demographic profile of alcohol dependence patients 2. To determine the prevalence and type of psychiatric co-morbidity in alcohol dependent patients. Methodology : A consecutive sample of 100 Alcohol Dependence Syndrome patients attending outpatient were selected. A questionnaire was administered to collect sample and alcohol dependence characteristics. psychiatric co-morbidity evaluation was done using Mini International Neuropsychiatric Interview (MINI Plus) and the diagnosis was confirmed by using ICD-10. Results : Majority of the subjects were young adults with a mean age of 42 years, were illiterates, married, employed, belonged to rural background and from lower socio-economic status. psychiatric co-morbidities were present in 33% of population. More of affective spectrum (18%) as compared with lesser numbers of patients in the anxiety (11%) or psychotic spectrum (4%). psychiatric co-morbidity is significantly greater in those who are unemployed. Conclusions: The psychiatric co-morbidity was present in 33% of the population studied. More of affective spectrum, followed by anxiety spectrum and less number of them in psychotic spectrum. All psychiatric co-morbidities may need to be identified for patients diagnosed as alcohol dependence who present with longer duration of drinking and unemployed for effective and comprehensive management.


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