scholarly journals Validity of infant face skin assessment by parents at home

2020 ◽  
Vol 4 (4) ◽  
pp. 159-164
Author(s):  
Kaori Yonezawa ◽  
Megumi Haruna ◽  
Reiji Kojima
Keyword(s):  
Barrier Function ◽  
Skin Barrier ◽  
Skin Condition ◽  
Future Research ◽  
Skin Barrier Function ◽  
Cross Sectional ◽  
Parental Assessment ◽  
Skin Ph ◽  
Skin Conditions ◽  
At Home

Parents had better to assess their infant’s skin daily to prevent the development of any skin problems. However, there are no standard methods for assessing infant skin at home. This study aimed to validate the assessment of infant face skin conditions by parents as compared to using skin barrier function clinical tests. In addition, we evaluated the degree of agreement between parents and physicians/midwives when assessing an infant’s skin. A cross-sectional study involving 184 infants aged 3 months was conducted. To evaluate the parents’ infant skin assessment, we used the Neonatal Skin Condition Score (NSCS). On the same day, we evaluated the skin barrier function on the infant’s forehead and cheek, including transepidermal water loss (TEWL), stratum corneum hydration, skin pH, and sebum secretion. Skin barrier function values were correlated with infant skin condition assessed by parents, especially in cases of TEWL of the cheek, for which a moderate positive correlation was found between parental assessment score (ρ = 0.448). In addition, infant with skin problems based on parental assessment had a significantly higher TEWL, lower SCH, and higher skin pH. However, there was weak agreement between parental and physician/midwife assessment. Thus, there was a relationship between parental assessment and skin barrier function; thus, parents can use at-home assessment to assist with infant skin care. In the future, research focused on developing methods of examining infant skin conditions should consider incorporate parental daily skin assessment.

scholarly journals Ph value of infant’s skin is higher on diaper area compared to nondiaper area

2019 ◽  
Author(s):  
Nadia Wirantari ◽  
Linda Astari ◽  
Iskandar Zulkarnain
Keyword(s):  
Barrier Function ◽  
Ph Value ◽  
Skin Barrier ◽  
Cross Sectional Study ◽  
Skin Barrier Function ◽  
Cross Sectional ◽  
Ph Values ◽  
Skin Ph ◽  
Significant Difference ◽  
The Difference

Prolonged use of diaper may alter skin barrier function due to exposure to irritants from feces and urine, concurrent mechanical friction and occlusion, thus render the skin prone to inflammation and infection. Measurement of skin pH value may be used to document skin barrier function, especially in tropical countries such as Indonesia, and to expose the difference between diapered and non-diapered skin. The purpose of this study is to compare the pH value between baby’s diapered and non-diapered skin. In this cross-sectional study, the skin pH of 43 healthy babies aged 6 to 12 months were measured using pH-meter on diaper and non-diaper area of the skin. pH values were documented and compared. The mean pH value of diaper area was 6,11 ± 0,72 g/m2/h (95% CI, 4,88 – 8,02) and non-diaper area was 5,91 ± 0,69 g/m2/h (95% CI, 4,53 – 7,69), with significant difference (p=0,005). pH values increased significantly on diaper area compared to nondiaper area, revealing impaired barrier function on diapered skin, despite no pathological skin changes.

scholarly journals Atopic Dermatitis as a Multifactorial Skin Disorder. Can the Analysis of Pathophysiological Targets Represent the Winning Therapeutic Strategy?

2020 ◽  
Vol 13 (11) ◽  
pp. 411
Author(s):  
Irene Magnifico ◽  
Giulio Petronio Petronio ◽  
Noemi Venditti ◽  
Marco Alfio Cutuli ◽  
Laura Pietrangelo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Atopic Dermatitis ◽  
Barrier Function ◽  
Scientific Evidence ◽  
Alternative Therapy ◽  
Skin Barrier ◽  
Skin Condition ◽  
Skin Barrier Function ◽  
Keywords Atopic Dermatitis ◽  
Immunological Dysfunction

Atopic dermatitis (AD) is a pathological skin condition with complex aetiological mechanisms that are difficult to fully understand. Scientific evidence suggests that of all the causes, the impairment of the skin barrier and cutaneous dysbiosis together with immunological dysfunction can be considered as the two main factors involved in this pathological skin condition. The loss of the skin barrier function is often linked to dysbiosis and immunological dysfunction, with an imbalance in the ratio between the pathogen Staphylococcus aureus and/or other microorganisms residing in the skin. The bibliographic research was conducted on PubMed, using the following keywords: ‘atopic dermatitis’, ‘bacterial therapy’, ‘drug delivery system’ and ‘alternative therapy’. The main studies concerning microbial therapy, such as the use of bacteria and/or part thereof with microbiota transplantation, and drug delivery systems to recover skin barrier function have been summarized. The studies examined show great potential in the development of effective therapeutic strategies for AD and AD-like symptoms. Despite this promise, however, future investigative efforts should focus both on the replication of some of these studies on a larger scale, with clinical and demographic characteristics that reflect the general AD population, and on the process of standardisation, in order to produce reliable data.

scholarly journals Homemade Kefir Consumption Improves Skin Condition—A Study Conducted in Healthy and Atopic Volunteers

Foods ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2794
Author(s):  
Emília Alves ◽  
João Gregório ◽  
André Rolim Baby ◽  
Patrícia Rijo ◽  
Luis M. Rodrigues ◽  
...  
Keyword(s):  
Barrier Function ◽  
Skin Diseases ◽  
Skin Barrier ◽  
Skin Condition ◽  
Skin Barrier Function ◽  
Fermented Foods ◽  
Inflammatory Skin Diseases ◽  
Health Promoting ◽  
Relationship Of ◽  
The Impact

Diet has a fundamental role in the homeostasis of bodily functions, including the skin, which, as an essential protective barrier, plays a crucial role in this balance. The skin and intestine appear to share a series of indirect metabolic pathways, in a dual relationship known as the “gut–skin axis”. Hence, the gut–skin axis might be receptive to modulation via dietary modification, where probiotics can be included, thus representing a potential therapeutic target in inflammatory skin diseases, such as atopic dermatitis (AD), in order to control and/or ameliorate symptoms. Kefir is one of the most ancient fermented foods, with probiotic characteristics that have been associated with a wide variety of health-promoting benefits, and it presents a microbiological diversity that makes its application as a probiotic in the gut–skin relationship of the utmost interest. However, the impact of a diet containing kefir on skin health has yet to be reported in scientific literature. This study aimed to assess the impact of the intake of homemade kefir in the skin of healthy and atopic volunteers. The intervention resulted in a boost on barrier function in both skin types verified only in the respective kefir intake groups. An improvement in the degree of severity of AD was also confirmed for the kefir intake group. Atopic individuals may benefit from kefir intake, especially in regard to their skin hydration. Finally, the effects observed on skin barrier function in this study probably culminate from the effects of all the ingredients in kefir, including the complex microbiota, its metabolites and macro- and micronutrients resulting from the fermentation. This work opens the way for more advanced research on the impact of the probiotic kefir on cutaneous health, further clarifying its mechanism of action namely via gut–skin axis.

Die Rolle des pH-Wertes bei Intertrigo oder zu trockener Haut

2019 ◽  
Vol 7 (3) ◽  
pp. 134-136
Author(s):  
Markus Braun-Falco
Keyword(s):  
Barrier Function ◽  
Good Condition ◽  
Age Groups ◽  
Skin Barrier ◽  
Skin Care ◽  
Skin Barrier Function ◽  
Permeability Barrier ◽  
Buffer System ◽  
Skin Conditions ◽  
Skin Care Products

In order to maintain skin in «good condition» one can use cosmetic products. Importantly, those skin care products should fulfil specific requirements for specific life phases and specific skin conditions. In this review, we focused on 2 different age groups - namely, infants and the elderly - as well as on 2 specific skin conditions occurring in both age groups - very dry skin (Xerosis) and hyperhydrated skin (diaper rash). The goal in both conditions should be to maintain skin surface in its physiological acidic state, which is in turn crucial for the permeability barrier function, stratum corneum integrity/cohesion and antimicrobial defense. Skin care products formulated with an effective buffer system at a more acidic pH, for example 4, may be the best option to improve the acid mantle and skin barrier function and thus keep the skin in «good condition».

scholarly journals Epidermal Barrier Function and Skin Homeostasis in Skin with Permanent and Adhesive Tattoos: A Cross-Sectional Study

2021 ◽  
Vol 10 (4) ◽  
pp. 888
Author(s):  
Jose-Pablo Serrano-Serra ◽  
Trinidad Montero-Vilchez ◽  
Agustin Buendia-Eisman ◽  
Salvador Arias-Santiago
Keyword(s):  
Barrier Function ◽  
Current Trend ◽  
Skin Barrier ◽  
Transepidermal Water Loss ◽  
Cross Sectional Study ◽  
Skin Barrier Function ◽  
Cross Sectional ◽  
Epidermal Barrier ◽  
Stratum Corneum Hydration ◽  
Before And After

Tattoos are a current trend, but their impact on skin homeostasis and epidermal barrier function is not well known. So, the aims of this study are (1) to investigate epidermal barrier function and skin homeostasis in skin with permanent tattoos, adhesive temporary tattoos and non-tattooed skin, and (2) to analyze the effect of petrolatum on skin with permanent and adhesive tattoos. In total, 67 tattoos were enrolled (34 permanent tattoos and 33 adhesive tattoos). Temperature, transepidermal water loss (TEWL), stratum corneum hydration (SCH), erythema and total antioxidant capacity (TAC) were measured in skin with permanent tattoos, adhesive tattoos and non-tattooed skin before and after petrolatum application. The temperature was lower (30.47 °C vs. 31.01 °C; p = 0.001) on skin with permanent tattoos than non-tattooed skin, while SCH (48.24 Arbitrary Units (AU) vs. 44.15 AU; p = 0.008) was higher. Skin with adhesive tattoos showed lower temperature, SCH (21.19 AU vs. 41.31 AU; p < 0.001) and TAC (1.27 microcoulombs (uC) vs. 3.48 uC; p < 0.001), and higher TEWL (8.65 g/h/m2 vs. 6.99 g/h/m2; p = 0.003), than non-tattooed skin. After petrolatum application, the temperature decreased on skin with permanent tattoos, and TEWL and SCH decreased on skin with adhesive tattoos. Adhesive tattoos may affect skin barrier function, while permanent tattoos may have a lower impact. Tattooed and non-tattooed skin responds in different ways to moisturizers.

scholarly journals Noninvasive Skin Barrier Assessment: Multiparametric Approach and Pilot Study

Cosmetics ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. 20 ◽  
Author(s):  
Jade Logger ◽  
Jill Olydam ◽  
Wietske Woliner-van der Weg ◽  
Piet van Erp
Keyword(s):  
Pilot Study ◽  
Water Content ◽  
Barrier Function ◽  
Skin Diseases ◽  
Skin Barrier ◽  
Transepidermal Water Loss ◽  
Future Research ◽  
Skin Barrier Function ◽  
Epidermal Thickness ◽  
Inflammatory Skin Diseases

The epidermal barrier function is disrupted in various inflammatory skin diseases. Accurate methods to measure skin barrier function are needed to assess the effect of therapeutic agents. Therefore, we developed a noninvasive multiparametric approach to measure four different parameters regarding the skin barrier. In the current pilot study, we evaluate this method in 14 healthy volunteers. We assessed erythema, transepidermal water loss (TEWL), water content, and epidermal thickness at both cheeks before and 30 min after application of Lanette and Vaseline-Lanette cream. For this, we used spectrophotometry, the Aquaflux device, the Epsilon device, and reflection confocal microscopy, respectively. Stratum corneum (SC) thickness was significantly increased after application of both creams (p < 0.05), and this increase was larger after Lanette cream compared to after Vaseline-Lanette cream (p = 0.035). Erythema, TEWL, and water content did not significantly change after cream application. Our multiparametric approach is promising and offers a feasible and practical way to quickly obtain multifaceted information about skin barrier function. Further exploration of this approach after prolonged use of cream and in conditions of disrupted skin barrier are recommended areas for future research.

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