The structure of “internal conflict” and “internal vacuum” as a result of dissociation between the choice of values and their availability in women with depression of different origin and different severity of macro-, meso- and micro-maladjustment

Annotation. The aim is to study the features of the structure of “internal conflict” and “internal vacuum” as a result of the dissociation between the choice of vital values and their availability in women with depression of different genesis and different severity of macro-, meso- and microsocial maladaptation, further targeted targets of personalized treatment and rehabilitation. The study included 94 individuals with a depressive disorder of psychogenic origin (prolonged depressive response due to an adaptation disorder), 83 women with endogenous depression (depressive episode; recurrently depressive disorder; bipolar affective disorder, current episode of depression), and 75 depressed of depression (organic affective disorders). The study was conducted using clinical psychopathological and psychodiagnostic methods. 48 women had no signs of psychosocial maladaptation, while the other 204 showed manifestations of macro-, meso-, and microsocial maladaptation of different severity. The study was conducted using clinical psychopathological and psychodiagnostic methods. The technique of studying the value orientations in the modification of O.B. Fantalova was used. The fountain. Statistical and mathematical analysis included the formation of descriptive statistics and the analysis of differences using nonparametric methods. The study revealed important patterns of transformation of the value-motivational sphere of women suffering from depressive disorders, depending on the severity of macro-, meso- and micro-social maladaptation, namely, an increase in the absolute dissociation rate as the signs of maladaptation increase in all spheres, spheres of health, active life, materially secured life, freedom as independence in actions and actions and creativity. The greatest dissociation by type of internal conflict (valuable but inaccessible) was found in the spheres of health, happy family life and material life. The greatest dissociation by type of internal vacuum (accessible but not valuable) is found in the fields of beauty of nature and art, cognition and creativity. The data obtained should be taken into account when developing treatment and rehabilitation measures for a given contingent of patients.

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Features of the relationship between severity of macrosocial maladaptation and anxiety-depressive symptoms in women with different genesis depressive disorders

Archives of psychiatry ◽

10.37822/2410-7484.2019.25.3.136-141 ◽

2019 ◽

Vol 25 (3) ◽

pp. 136-141

Author(s):

R. I. Isakov

Keyword(s):

Depressive Symptoms ◽

Depressive Disorder ◽

Patient Population ◽

Depressive Disorders ◽

Endogenous Depression ◽

Direct Association ◽

Leading Position ◽

Number Of Publications ◽

The Relationship ◽

Pathological Anxiety

Background. The leading position in the structure of the pathology of the psyche today is convincingly held by depressive disorders. In recent years, the number of publications showing a combination of the frequency of depression and psychosocial maladaptation, which acts both as a derivative in the clinic of depressive disorders and as an independent phenomenon that provokes and aggravates their course, has increased. Objective – to study the correlation of the structure and severity of the manifestations of macrosocial maladaptation and anxiety-depressive symptoms in women with depressive disorders of various genesis, in order to further determine the targeted points for differentiated psychosocial rehabilitation of this patient population. Materials and methods. 252 women with a diagnosis of depressive disorder were examined: 94 women with depressive disorder of psychogenic genesis (F43.21), 83 women with endogenous depression, (F32.0, F32.1, F32.2, F32.3, F33.0, F33. 1, F33.2, F33.3, F31.3, F31.4, F31.5) and 75 women with depressive disorder of organic genesis (F06.3). According to the results of assessing the degree of macrosocial maladaptation, two groups were distinguished: women without signs of maladaptation were assigned to the first group (n=48); the second group (n=204) consisted women with identified signs of maladaptation. We used such research methods: clinical-psychopathological, psychodiagnostic, statistical. Results. The regularities between the genesis of depression and the severity of signs of macrosocial maladaptation and anxiety are established and described. Macrosocial maladaptation of various severity occurs in the vast majority of patients with depression of any genesis. The severity and variability of pathological anxiety is the lowest in women with psychogenic depression with no or mild macrosocial disadaptation, and high in severe maladaptation, meanwhile in patients with endogenous depression the severity of anxiety is highest with mild maladaptation and low with severe macrosocial maladaptation. Conclusions. The severity of macrosocial maladaptation does not demonstrate a direct association with the severity of depressive phenomena and a clear comparability with the genesis of depressive disorder. Anxiety is less dependent on the genesis of depression, and is more determined by the degree of maladaptation. Received data should be taken into account when developing diagnostic, treatment and rehabilitation measures for women with depressive disorders.

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CHARACTERISTICS OF COGNITIVE IMPAIRMENT IN PATIENTS WITH DEPRESSIVE DISORDERS

Експериментальна і клінічна медицина ◽

10.35339/ekm.2020.86.01.06 ◽

2020 ◽

Vol 86 (1) ◽

pp. 41-49

Author(s):

S. A. Yaroslavtsev

Keyword(s):

Differential Diagnosis ◽

Cognitive Impairment ◽

Depressive Disorder ◽

Affective Disorder ◽

Depressive Disorders ◽

Bipolar Affective Disorder ◽

Cognitive Dysfunctions ◽

Visual Spatial ◽

Linguistic Functions ◽

Depressive Reaction

362 patients with cognitive impairment in depressive disorders were examined: 123 patients with recurrent depressive disorder (RDD), 141 patients with bipolar affective disorder (BAD) and 98 people with prolonged depressive reaction (PDR). It was found that cognitive dysfunctions were less pronounced in patients with PDR, than in patients with RDD and BAR (p<0,035). Cognitive dysfunctions in depressive disorders was underlined by the presence of disorders in the mental sphere, in the sphere of attention, executive, visual-spatial and linguistic functions. The differential features of cognitive impairment in patients with RDD, BAR and PDR are highlighted and it should be taken during conducting differential diagnosis of cognitive impairment in depressive disorders. Keywords: patients with cognitive impairment, depressive disorders, cognitive dysfunctions, recurrent depressive disorder, bipolar depressive disorder, prolonged depressive reaction.

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STRUCTURAL ANALYSIS OF SOCIO-PSYCHOLOGICAL MALADAPTATION IN WOMEN WITH DEPRESSIVE DISORDERS OF DIFFERENT GENESIS, DEPENDING ON SEVERITY OF FACTORS OF MESO- AND MICRO-SOCIAL INFLUENCE

Експериментальна і клінічна медицина ◽

10.35339/ekm.2020.86.01.04 ◽

2020 ◽

Vol 86 (1) ◽

pp. 21-30

Author(s):

R. I. Isakov

Keyword(s):

Structural Analysis ◽

Depressive Disorder ◽

Internal Control ◽

Psychosocial Functioning ◽

Depressive Disorders ◽

Psychological Adaptation ◽

Endogenous Depression ◽

External Control ◽

Previous Hypothesis ◽

Inducing Factors

To conduct a structural analysis of socio-psychological maladaptation in women with depressive disorders of different genesis depending on the severity of meso- and microsocial influences, to develop personalized psychosocial rehabilitation measures for this group of patients, 252 women were examined and diagnosed with depressive 94 with depressive disorder of psychogenic genesis, 83 women with endogenous depression and 75 patients with depressive disorder of organic genesis. Patients were divided into groups depending on the genesis of depressive disorder and the presence and severity of problems in psychosocial functioning. The study was conducted using clinical-psychopathological and psychodiagnostic methods. The study confirmed the previous hypothesis about the association of the manifestations of socio-psychological maladaptation as a structural component of depression, depending on the vulnerability to meso- and microsocial stress-inducing factors, with any genesis of depressive disorder. There is a tendency to increase the signs of maladaptation, self-rejection, rejection of other emotional discomfort, external control, and information, and decrease signs of adaptability, truthfulness, self-acceptance, acceptance of others, emotional comfort, internal control, dominance with increasing load as meso- and and microsocial factors. The most pronounced differences in the indicators of socio-psychological maladaptation were found in people with microsocial problems, less pronounced - in mesosocial maladaptation. The identified patterns should be taken into account in the development of treatment and rehabilitation and preventive measures for depressive disorders in women. Keywords: depressive disorders, women, socio-psychological adaptation, mesosocial maladaptation, microsocial maladaptation.

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Peculiarities of the perception process in patients with cognitive impairments in depressive disorders

Ukrains'kyi Visnyk Psykhonevrolohii ◽

10.36927/2079-0325-v28-is3-2020-9 ◽

2020 ◽

pp. 58-62

Author(s):

Serhii Yaroslavtsev

Keyword(s):

Cognitive Impairment ◽

Depressive Disorder ◽

Depressive Disorders ◽

High Selectivity ◽

Bipolar Affective Disorder ◽

Negative Stimulus ◽

Neutral Stimulus ◽

Positive Stimulus ◽

Perception Process ◽

Depressive Reaction

362 patients with cognitive impairment in depressive disorders were examined: 123 patients with recurrent depressive disorder (RDD), 141 patients with bipolar affective disorder (BAD) and 98 patients with prolonged depressive reaction (PDR). A set of research methods was used: clinical-psychopathological, psychodiagnostic (Munsterberg test) and statistical. The features of the perception process were established for various types of depressive disorders: in patients with RDD, there was a predominance of average, increased and decreased selectivity of attention to neutral stimulus (30.89 %, 21.95 % and 21.95 %, respectively), high selectivity of attention to negative stimulus (33.33 %) and decreased and low selectivity of attention to positive stimulus (54.47 % and 20.33 %, respectively); in patients with BAD, a predominance of average and reduced selectivity of attention to neutral stimulus (45.39 % and 36.17 %, respectively) and average selectivity of attention to negative and positive stimulus (38.30 % and 38.30 %, respectively) were recorded; in patients with PDR, the prevalence of average and reduced selectivity of attention to neutral stimulus (42.86 % and 34.69 %, respectively), increased and decreased selectivity of attention to negative stimulus (29.59 % and 16.33 %, respectively), increased selectivity of attention to positive stimulus (43.88 %). Key words: patients with cognitive impairment, depressive disorders, perception process, recurrent depressive disorder, bipolar depressive disorder, prolonged depressive reaction

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Emotional sphere disorders in patients with cognitive impairments in depressive disorders

Ukrains'kyi Visnyk Psykhonevrolohii ◽

10.36927/2079-0325-v28-is4-2020-9 ◽

2020 ◽

pp. 51-54

Author(s):

Serhii Yaroslavtsev

Keyword(s):

Cognitive Impairment ◽

Depressive Disorder ◽

Affective Disorders ◽

Depressive Disorders ◽

Cognitive Impairments ◽

Bipolar Affective Disorder ◽

Emotional Lability ◽

Low Mood ◽

Different Types ◽

Depressive Reaction

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Predictors of suicidal behavior in patients with cognitive impairments in depressive disorders

Bukovinian Medical Herald ◽

10.24061/2413-0737.xxiv.4.96.2020.103 ◽

2020 ◽

Vol 24 (4 (96)) ◽

pp. 58-64

Author(s):

N. Maruta ◽

S. Yaroslavtsev

Keyword(s):

Cognitive Impairment ◽

Depressive Disorder ◽

Interpersonal Relationships ◽

Suicidal Behavior ◽

Cognitive Functions ◽

Affective Disorders ◽

Suicide Risk ◽

Depressive Disorders ◽

Bipolar Affective Disorder ◽

Autonomic Disorders

The aim of the study was to determine predictors of suicide risk in patients with cognitive impairment in depressive disorders.Material and methods. 362 patients with cognitive impairment in depressive disorders were examined: 123 patients with recurrent depressive disorder, 141 patients with bipolar affective disorder and 98 patients with prolonged depressive reaction. A set of research methods was used to study the factors of suicidal behavior in patients with cognitive impairment in depressive disorders: clinical-psychopathological, psychodiagnostic (questionnaire "Self-assessment of the severity of autoaggressive predictors") and mathematical-statistical. Results of the research. Predictors of suicide risk in patients with cognitive impairment in depressive disorders were identified. The moderate level of autoaggression and aggression, low level of impulsivity, high and severe narrowing of cognitive functions, severe narrowing of interpersonal relationships, severity of affective disorders, moderate and severe autonomic disorders were identified in patients with recurrent depressive disorder. Pronounced and moderate level of autoaggression, aggression and impulsivity, high and pronounced level of narrowing of cognitive functions, pronounced narrowing of interpersonal relationships, severity of affective disorders, moderate and severe level of autonomic disorders were identified in patients with bipolar affective disorder. Moderate levels of autoaggression and narrowing of cognitive functions, low levels of aggression, severe impulsivity, affective disorders and narrowing of interpersonal relationships, and high levels of autonomic disorders were identified in patients with prolonged depressive reaction.Conclusions. As a result of the study, the features of suicidal behavior in patients with cognitive impairment in depressive disorders were identified. It can act as diagnostic criteria and predictors of suicidal behavior in differential diagnostics and could take into account when creating psychocorrectional programs aimed at reducing suicidal risk in patients with cognitive dysfunctions in depressive disorders.

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Peculiarities of the attention process at depressive disorders

Ukrains'kyi Visnyk Psykhonevrolohii ◽

10.36927/2079-0325-v28-is2-2020-11 ◽

2020 ◽

pp. 55-59

Author(s):

Serhii Yaroslavtsev

Keyword(s):

Differential Diagnosis ◽

Cognitive Impairment ◽

Depressive Disorder ◽

Key Words ◽

Depressive Disorders ◽

Bipolar Affective Disorder ◽

Work Efficiency ◽

Working Capacity ◽

Attention Process ◽

Depressive Reaction

362 patients with cognitive impairment in depressive disorders were examined: 123 patients with recurrent depressive disorder, 141 patients with bipolar affective disorder and 98 people with prolonged depressive reaction. Peculiarities of the process of attention of patients with depressive disorders were the presence of a decrease in concentration, stability and switching of attention, decrease in work efficiency and working capacity. The peculiarities of the functioning of attention indicators were determined for various types of depressive disorders, which can use as diagnostic criteria in the differential diagnosis of cognitive impairment in depressive disorders. Key words: cognitive impairment, depressive disorders, persistence, concentration and switching of attention, recurrent depressive disorder, bipolar depressive disorder, prolonged depressive reaction

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The Genetics of Depression and Manic-Depressive Disorder

The British Journal of Psychiatry ◽

10.1192/bjp.155.3.294 ◽

1989 ◽

Vol 155 (3) ◽

pp. 294-304 ◽

Cited By ~ 126

Author(s):

Peter McGuffin ◽

Randy Katz

Keyword(s):

Depressive Disorder ◽

Family Environment ◽

Depressive Disorders ◽

Familial Aggregation ◽

Unipolar Depression ◽

Endogenous Depression ◽

Depressive Illness ◽

Manic Depressive Illness ◽

Familial Predisposition ◽

Manic Depressive

Depressive disorders are more common in the relatives of depressed probands than in the population at large, and there is compelling evidence that the familial aggregation of bipolar disorder and severe unipolar depression is at least partly due to genetic factors. However, the evidence concerning ‘non-endogenous' depression is less clear, and family environment probably plays a stronger role. Much current research is focused on two areas: firstly, the mode of inheritance of manic-depressive illness, with the use of molecular biological techniques to detect and localise major genes; and secondly, the ways in which familial predisposition and environmental insults combine to produce depressive disorder.

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Depressive Disorders: Update on Diagnosis, Etiology, and Treatment

10.2310/tywc.1640 ◽

2018 ◽

Author(s):

Isabelle E. Bauer ◽

Antonio L Teixeira ◽

Marsal Sanches ◽

Jair C. Soares

Keyword(s):

Depressive Disorder ◽

Depressive Disorders ◽

Treatment Strategies ◽

Premenstrual Dysphoric Disorder ◽

Brain Volumes ◽

Somatic Therapy ◽

Diagnostic And Statistical Manual ◽

Dsm 5 ◽

History Of ◽

Persistent Depressive Disorder

This review discusses the changes in the diagnostic criteria for depressive disorders as outlined in the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), and recent findings exploring the etiology of and treatment strategies for these disorders. Depressive disorders are typically characterized by depression in the absence of a lifetime history of mania or hypomania. New developments in the DSM-5 include the recognition of new types of depressive disorders, such as disruptive mood dysregulation disorder, persistent depressive disorder, premenstrual dysphoric disorder, and the addition of catatonic features as a specifier for persistent depressive disorder. These diagnostic changes have important implications for the prognosis and treatment of this condition. A thorough understanding of both the clinical phenotype and the biosignature of these conditions is essential to provide individualized, long-term, effective treatments to affected individuals. This review contains 1 table and 52 references Key words: brain volumes, depressive disorders, DSM-5, hormones, inflammation, neuropeptides, somatic therapy, stress

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Prevalence and Recognition of Depressive Disorders in General Medical Inpatients

The International Journal of Psychiatry in Medicine ◽

10.2190/wr82-6x7y-4uxc-0tf9 ◽

1988 ◽

Vol 17 (4) ◽

pp. 341-349 ◽

Cited By ~ 21

Author(s):

Michiel W. Hengeveld ◽

Frans A. J. M. Ancion ◽

Harry G. M. Rooijmans

Keyword(s):

Depressive Disorder ◽

Depressive Disorders ◽

Length Of Hospital Stay ◽

University Hospital ◽

Psychiatric Consultation ◽

Consultant Psychiatrist ◽

Symptoms Of Depression ◽

Medical Inpatients ◽

Medical Wards ◽

Depressive Patients

The Beck Depression Inventory (BDI) was administered to 220 of 340 patients consecutively admitted to three general medical wards of a University Hospital, whose length of hospital stay was more than five days. At least mild symptoms of depression (BDI ≥ 13) were reported by 70/220 (32%) of the patients. Alternate BDI depressive patients underwent psychiatric consultation. The psychiatric consultant established a DSM-III depressive disorder in 10/33 (30%) of these patients. Only 3/10 (30%) of the DSM-III depressive patients had been referred to the consultant psychiatrist by their physician.

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