scholarly journals Ossifying Fibroma of the Maxilla: A Case Report and Literature Update

2021 ◽  
pp. 1-4
Author(s):  
Abdouldaim Ukwas ◽  
Abdouldaim Ukwas ◽  
Mohammed Magdy ◽  
Mahmoud Elshik
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Bone Grafting ◽  
Fibrous Tissue ◽  
Definitive Diagnosis ◽  
Ossifying Fibroma ◽  
Normal Bone ◽  
Calcified Tissues ◽  
Slow Growing ◽  
Normal Bone Tissue

Ossifying fibroma is a rare benign fibro-osseous neoplasm of the jaw characterized by the replacement of normal bone tissue by a combination of fibrous tissue and newly formed calcified tissues of bone and/or cementum-like material. Lesions often manifest at the 2nd to 4th decades of life with a predominant female predilection. The tumor is usually slow-growing and asymptomatic but can cause notable expansion of the jawbones. Definitive diagnosis of OF can be challenging and usually requires careful clinical, radiographic and histologic assessments. Treatment commonly depends on the size, location and aggressiveness of tumor and can accordingly vary from enucleation and curettage to resection and bone grafting. The prognosis is generally good when the lesion is completely removed, but recurrence is possible in some circumstances. The aim of this article is to present a case report of a recurrent ossifying fibroma in a 28-year-old female patient and to provide an update of the literature.

scholarly journals Monostotic Fibrous Dysplasia Involving the Mandible: A Case Report

2020 ◽  
Vol 8 ◽  
pp. 2050313X2093695
Author(s):  
Khalil Ibrahim Assiri
Keyword(s):  
Case Report ◽  
Fibrous Dysplasia ◽  
Fibrous Tissue ◽  
Malignant Potential ◽  
Definitive Diagnosis ◽  
Rapid Progression ◽  
Polyostotic Fibrous Dysplasia ◽  
Clinical Behavior ◽  
Normal Bone ◽  
Examination Methods

Fibrous dysplasia (FD) is a skeletal developmental anomaly, which is non-hereditary and idiopathic in origin. It is characterized by the replacement of normal bone with the excess proliferation of fibrous tissue in irregular bony trabeculae. Patients might complain of swelling, pain, or numbness on the affected side. The incidence of monostotic FD (MFD) is four times more than that of polyostotic fibrous dysplasia. In MFD, the maxilla is more commonly affected than the mandible. The clinical behavior and rapid progression of FD renders the treatment challenging. The malignant potential is 0.5% for untreated cases. Here, we present a case of FD involving the mandible. The clinical diagnostic approach, different imaging modalities, and histological examination methods for definitive diagnosis have been elaborated.

scholarly journals A Huge Cemento-Ossifying Fibroma of Paranasal Sinus: A Case Report

2012 ◽  
Vol 55 (3) ◽  
pp. 146-149
Author(s):  
Ibrahim Erdim ◽  
Zahide Mine Yazici ◽  
Rasim Yilmazer ◽  
Nurten Sever ◽  
Fatma Tulin Kayhan
Keyword(s):  
Case Report ◽  
Paranasal Sinus ◽  
Male Patient ◽  
Paranasal Sinuses ◽  
Surgical Excision ◽  
Ossifying Fibroma ◽  
Radiological Appearance ◽  
Close Observation ◽  
Slow Growing

Cemento-ossifying fibroma is a well-bordered, slow-growing, benign fibro-osseous disease. Although its localization is generally in the mandible, it can be seen in any area of the craniofacial region. Radiology and histopathology help to diagnose the condition. Treatment is based on close observation and/or surgical excision. In this case, we report the case of a 62-year-old male patient who had a large radiological appearance, cemento-ossifying fibroma in the paranasal sinuses.

scholarly journals PD-1, TIM-3 and LAG-3 Expression in T Cells in a Patient with Recurrent Ossifying Fibroma. A Case Report.

2020 ◽  
Author(s):  
Alejandro García-Muñoz ◽  
Nayeli Goreti Nieto-Velázquez ◽  
Gabriela Damian-Morales ◽  
Carlos Liceaga-Escalera ◽  
Luis Alberto Montoya-Perez ◽  
...  
Keyword(s):  
T Cells ◽  
Case Report ◽  
T Cell ◽  
Peripheral Blood ◽  
Cytotoxic T Lymphocyte ◽  
Lymphocyte Activation ◽  
T Cell Response ◽  
Ossifying Fibroma ◽  
Slow Growing ◽  
Cell Death Protein

Abstract Background: Central ossifying fibroma is a benign, slow-growing tumor of mesenchymal origin with a predilection for the mandibular premolar and molar areas. The immunophenotype of T cells involved in the antitumor response against this benign tumor is unknown.Case presentation: In this case report, we described a case of a 48-year-old woman presenting with a very large recurrent ossifying fibroma in the mandible, which was successfully treated with hemimaxillectomy. In addition, we evaluated the expression of programmed cell death protein-1 (PD-1), lymphocyte activation gene-3 (LAG-3), T cell immunoglobulin and mucin-domain containing-3 (TIM-3), cytotoxic T lymphocyte-associated antigen-4 (CTLA-4), CD69 (activation inducer molecule) and CD25 (α chain of the high-affinity IL-2 receptor) in T cell populations from the tumor and peripheral blood of this uncommon lesion.Conclusions: The patient presented recurrent ossifying fibroma, and the tumor-infiltrating and peripheral blood T cells showed expression of PD-1, LAG-3, and TIM-3, suggesting an exhausted T cell response.

scholarly journals Gastric Schwannoma: A Postoperative Surprise A Case Report.

2014 ◽  
Vol 1 (1) ◽  
pp. 23-25
Author(s):  
Abdelmounaim Ait ALi ◽  
Mohamed Essarghini ◽  
Abderzak Hajjouji ◽  
Khalid Sair
Keyword(s):  
Case Report ◽  
Clinical Case ◽  
Submucosal Tumor ◽  
S100 Protein ◽  
Partial Gastrectomy ◽  
Definitive Diagnosis ◽  
Resected Specimen ◽  
Stromal Tumors ◽  
Gastric Schwannoma ◽  
Slow Growing

Gastric Schwannoma is a rare, slow-growing, and clinically non-specific submucosal tumor, originating from Schwann cells with excellent prognosis after surgical resection. We report a clinical case of a patient presented with gastric schwannoma revealed by non-specific gastric signs and of which the definitive diagnosis is done through immunohistochemistry of the resected specimen, showing strong S100 protein positivity. The evolution is favorable after a partial gastrectomy with a decline of two years. Through this case, we are trying to trace the rarity, strong similarities with gastric stromal tumors and especially, the weak index of suspicion for this diagnosis.

scholarly journals Mandibular Reconstruction with Autogenous Graft After Surgical Treatment of Cemento-Ossifying Fibroma: a Case Report and Literature Review

2021 ◽  
Vol 1 (2) ◽  
pp. 3-14
Author(s):  
Rodrigo Lemos Alves ◽  
Jonas Nogueira Ferreira Maciel Gusmão ◽  
Bruno Frota Amora Silva ◽  
Rodrigo Cristhian Avelino Bezerra ◽  
Eliardo Silveira Santos ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Iliac Crest ◽  
Bone Dysplasia ◽  
Mandibular Reconstruction ◽  
Bone Lesions ◽  
Ossifying Fibroma ◽  
Microscopic Appearance ◽  
Autogenous Graft ◽  
Normal Bone Tissue

Fibro-bone lesions (LFO) are defined as a group of lesions characterized by the replacement of normal bone tissue with fibrous connective tissue, of variable cellularity, permeated by a variable amount of mineralized material, whose microscopic appearance may resemble bone, cement or a mixture of both. Among the injuries that make up this group, we can mention: fibrous dysplasia, ossifying fibroma, bone dysplasia and cemento-bone dysplasia. In this case report, we presented a mandibular reconstruction with free autogenous graft from the iliac crest, with the use of stereolithography prototyping, after the surgical treatment of a cemento-ossifying fibroma, as well as to describe the clinical, epidemiological, radiographic characteristics, and histological, the differential diagnosis and the form of treatment of the referred pathology.

scholarly journals Fibrous dysplasia of maxilla – A rare case report

2021 ◽  
pp. 485-488
Author(s):  
Vijaya R Kamble ◽  
Shalini N Waghmare ◽  
Aditi V Rangari ◽  
Mangala Meti ◽  
Pritam Pohankar ◽  
...  
Keyword(s):  
Case Report ◽  
Fibrous Dysplasia ◽  
Female Patient ◽  
Malignant Transformation ◽  
Histological Examination ◽  
Rare Case ◽  
Definitive Diagnosis ◽  
Developmental Anomaly ◽  
Rare Case Report ◽  
Examination Methods

Fibrous dysplasia (FD) is a skeletal developmental anomaly, which is non-hereditary in origin and idiopathic in nature. It is a benign fibro-osseous disease that affects one or more bones. It usually affects unilaterally and is seen in the posterior region. Approximately 0.5% of untreated cases show the malignant transformation. We report the case of a 35-year-old female patient with FD involving the maxilla. The clinical diagnostic approach, different imaging modalities, and histological examination methods for definitive diagnosis have been elaborated.

scholarly journals Peripheral ossifying fibroma: A case report

2021 ◽  
Vol 6 (3) ◽  
pp. 179-183
Author(s):  
Sandip Ghosh ◽  
Balaji R ◽  
Ashit Kumar Pal ◽  
Somen Bagchi ◽  
Sandip Ghose
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Malignant Lesion ◽  
Clinical Findings ◽  
Anterior Tooth ◽  
Ossifying Fibroma ◽  
Peripheral Ossifying Fibroma ◽  
Cementifying Fibroma ◽  
Histopathological Evaluation ◽  
Human Gingiva

Localized inflammatory or reactive overgrowths are quite more common clinical findings on human gingiva. Most of the lesions are benign and innocuous though some have potency to transfer in to a malignant lesion. These types of lesions are difficult to identify clinically as their appearance are quite similar so only Histopathological evaluation can detect their identity. In this case report we displayed a case of Peripheral Ossifying Fibroma in maxillary anterior tooth region in 32 year old female patient along with clinical, Histopathological evaluation along with present and future treatment details. Peripheral ossifying fibroma (POF) is usually a fibromatic, non neoplastic enlargement of the gingiva which shows areas of calcification or ossification. Synonyms for POF include Peripheral cementifying fibroma, Peripheral fibroma with calcification, Calcifying or ossifying fibrous epulis and Calcifying fibroblastic granuloma.

scholarly journals Cemento-ossifying Fibroma Involving Mandible

2013 ◽  
Vol 2 (2) ◽  
pp. 127-129
Author(s):  
Kamran Bokhari ◽  
Mustafa Abdel Bagi ◽  
Mutasim Al Nager ◽  
Sulphi Abdul Basheer ◽  
Mohammed Abdullah M Assiri
Keyword(s):  
Male Patient ◽  
Growth Pattern ◽  
Fibrous Tissue ◽  
Ossifying Fibroma ◽  
Rare Neoplasm ◽  
Degree Of Mineralization ◽  
Odontogenic Lesion ◽  
Slow Growing

ABSTRACT Cemento-ossifying fibroma (COF) is a rare neoplasm representing one of the benign fibro-osseous lesions of the jaw. This benign mesenchymal odontogenic lesion occurs more frequently in women than in men. Clinically, these tumors are slow growing with a centrifugal growth pattern. Radiologically, COFs present a number of patterns depending on the degree of mineralization. Histologically, these lesions are characterized by fibrous tissue with islands of bone or cementiform calcifications. We present a case of COF involving mandible in a 35-year-old male patient treated by excision. How to cite this article Bagi MA, Bokhari K, Al Nager M, Basheer SA, Assiri MAM. Cemento-ossifying Fibroma Involving Mandible. Int J Experiment Dent Sci 2013;2(2):127-129.

scholarly journals PERIPHERAL CEMENTO-OSSIFYING FIBROMA – A CASE REPORT

2021 ◽  
pp. 1-3
Author(s):  
SARASWATHI GOPAL K ◽  
SANGAVI R ◽  
ARATHY L
Keyword(s):  
Case Report ◽  
Recurrence Rate ◽  
Benign Tumor ◽  
Ossifying Fibroma ◽  
Gingival Overgrowth ◽  
Slow Growing ◽  
Gingival Irritation ◽  
Considerable Size

Peripheral cemento-ossifying fibroma is a gingival overgrowth that occurs most commonly on the gingiva. It is a slow-growing reactive lesion. It is a benign tumor that grows to a considerable size and leads to pathologic migration of the teeth at later stages. It most commonly occurs following a gingival irritation or trauma. These lesions are said to arise from the PDL fibers excision of these lesions along with the periosteum is very important to avoid recurrence. The recurrence rate of peripheral cemento-ossifying fibroma has been reported to be 8–20%, so a close postoperative follow-up is required. Here, we are presenting two case of peripheral cemento-ossifying fibroma in the mandible.

scholarly journals Juvenile Aggressive Cemento-ossifying Fibroma of the Maxilla

2012 ◽  
Vol 4 (3) ◽  
pp. 156-159 ◽  
Author(s):  
Sarita Mishra ◽  
Sampan Singh Bist ◽  
Vinish Aggarwal
Keyword(s):  
Paranasal Sinuses ◽  
Rapid Growth ◽  
Fibrous Tissue ◽  
Ossifying Fibroma ◽  
Lamellar Bone ◽  
Diagnostic Dilemma ◽  
The Face ◽  
Slow Growing ◽  
Pathological Subtypes ◽  
Cheek Swelling

ABSTRACT Fibro-osseous lesions of the face and paranasal sinuses are relatively uncommon. The biological characteristics of fibroosseous lesions range from indolent to aggressive and from inflammatory to neoplastic. Cemento-ossifying fibroma is a rare, benign fibro-osseous lesion composed of lamellar bone, fibrous tissue and cementum. It is usually found in the jaw bone and presents in several variant pathological subtypes. The overlapping clinical, radiologic and histomorphologic features of these subtypes have led to diagnostic dilemma for the clinician, radiologist and the histopathologist. Clinically, the lesions are usually asymptomatic, slow-growing and wellcircumscribed. However, in very few cases, these tumors have demonstrated an aggressive course of development. Lesions that involve the midface and paranasal sinuses and presenting in earlier age tend to demonstrate aggressive behavior and rapid growth. We describe a case of a 13 years old young boy with aggressively behaving cemento-ossifying fibroma of the maxilla presenting acutely as right cheek swelling with gingival growth. How to cite this article Bist SS, Varshney S, Bhagat S, Mishra S, Aggarwal V. Juvenile Aggressive Cemento-ossifying Fibroma of the Maxilla. Int J Otorhinolaryngol Clin 2012;4(3):156-159.

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