Effect of a Hyperproteic Hyperenergetic Enteral Formula on Body Composition and VEGF in AML During Hospital Stay

Abstract Background: Analytic morphometric assessment has recently been proposed to be applied to the study of acute pancreatitis (AP). However, the relationship between body composition and the outcomes of hypertriglyceridemic pancreatitis (HTGP) is still unclear. The aim of this study was to evaluate body composition in relation to the length of hospital stay (LOS) and recurrence of HTGP.Methods: Patient characteristics, admission examination data, body composition parameters, LOS, and recurrence within 1 year were collected from the institutional pancreatitis database and follow-up records. Logistic regression analysis was used to identify risk factors for LOS and recurrence of HTGP.Results: Of the 196 included patients, 158 (80.6%) were men and 53 (27.0%) were sarcopenic. The average LOS was 15.83±10.02 days. The recurrence rate of HTGP was 36.7%. Multivariate analysis with multiple linear regression suggested that subcutaneous fat area (SFA) (p=0.019) and high-density lipoprotein-cholesterol (HDL-C) (p=0.001) were independently associated with the LOS for HTGP after adjusting for age and sex. The multivariate adjusted hazard ratios for SFA and HDL-C, with respect to the relationship between body parameters and LOS, were 1.008 (95% confidence interval [CI], 1.001–1.015) and 0.090 (95% CI, 0.022–0.361), respectively. No significant differences were observed between the AP and recurrent AP (RAP) groups in terms of characteristics, admission examination data, and body composition parameters.Conclusion: SFA and HDL-C are associated with LOS in patients with HTGP. The body composition of patients at the first symptom onset of HTGP cannot predict recurrence.

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Body composition in very preterm infants during their hospital stay

10.14264/uql.2018.177 ◽

2018 ◽

Author(s):

Nada Al-Theyab

Keyword(s):

Body Composition ◽

Hospital Stay ◽

Preterm Infants ◽

Very Preterm Infants ◽

Very Preterm

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Assessment of body composition and association with clinical outcomes in patients with lung and colorectal cancer

BJR|Open ◽

10.1259/bjro.20210048 ◽

2021 ◽

Author(s):

Naomi S Sakai ◽

Anisha Bhagwanani ◽

Timothy JP Bray ◽

Margaret A Hall-Craggs ◽

Stuart Andrew Taylor

Keyword(s):

Colorectal Cancer ◽

Lung Cancer ◽

Body Composition ◽

Hospital Stay ◽

Clinical Outcomes ◽

Fatty Infiltration ◽

Length Of Hospital Stay ◽

Fat Free Mass ◽

Whole Body ◽

Whole Body Mri

Objectives: To assess body composition in patients with non-small cell lung cancer (NSCLC) and colorectal cancer using whole body MRI and relate this to clinical outcomes. Methods: 53 patients with NSCLC (28 males, 25 females; mean age 66.9) and 74 patients with colorectal cancer (42 males, 32 females; mean age 62.9) underwent staging whole-body MRI scans which were post-processed to derive fat mass (FM), fat free mass (FFM) and skeletal muscle (SM) indices and SM fat fraction (FF). These were compared between the two cancer cohorts using two-sided t-tests and the chi-squared test. Measurements of body composition were correlated with outcomes including length of hospital stay, metastatic status and mortality. Results: Patients with NSCLC had significantly lower FFM (p = 0.0071) and SM (p = 0.0084) indices. Mean SM FF was greater in patients with NSCLC (p = 0.0124) and was associated with longer hospital stay (p = 0.035). There was no significant relationship between FM, FFM and SM indices and length of hospital stay, metastatic status or mortality. Conclusions: Patients with NSCLC had lower FFM and SM indices than patients with colorectal cancer and greater SMFF, indicating lower SM mass with fatty infiltration. These findings reflect differences in the phenotype of the two groups and suggest patients with lung cancer are more likely to require additional nutritional support. Advances in knowledge: Body composition differs between NSCLC and colorectal cancer. Patients with NSCLC have both a reduced SM mass and greater SM FF suggesting that they are more nutritionally deplete than patients with colorectal cancer.

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Peptide-based enteral formula vs a whole protein enteral formula after major intestinal surgeries in children

Annals of Pediatric Surgery ◽

10.1186/s43159-021-00112-9 ◽

2021 ◽

Vol 17 (1) ◽

Author(s):

Mohamed Saber Mostafa ◽

Yasmin Gamal ◽

Mohamed H. Soliman

Keyword(s):

Nutritional Status ◽

Hospital Stay ◽

Pediatric Patients ◽

Gut Hormones ◽

Common Finding ◽

P Value ◽

Peptide Group ◽

Average Hospital ◽

Formula Group ◽

Enteral Formula

Abstract Background Malnutrition is a common finding after major abdominal surgeries especially after prolonged period of fasting in children. Enteral feeding is the commonest support way postoperatively for stimulating gut hormones, modulating immunity, and maintaining the barrier function of the intestinal mucosa. Our aim was to compare the results and outcome regarding tolerance, nutritional status, and hospital stay following a postoperative diet of peptide-based enteral formula against a whole protein enteral formula after major intestinal surgeries in pediatric patients who had resection and re-anastomosis after intussusception. Results This is a prospective cohort study on two groups of patients with a total of 30 patients during the period between January 2019 and June 2020. All patients in both groups underwent major intestinal surgeries (resection and re-anastomosis after intussusception). The first group received postoperative whole protein formula exclusively on the 3rd postoperative day while the other group received peptide-based formula exclusively on the same day. Postoperative mean serum albumin and pre-albumin levels were significantly higher in peptide-based formula group compared to those who had protein-based formula as their initial feeds (P value < 0.05). The average hospital stay was also significantly shorter in the peptide group (P value < 0.05). Peptide formula was easily tolerated than protein formula in postoperative children who had major intestinal surgeries. Conclusion Peptide-based enteral formulas are better tolerated and more useful as regards nutritional status than whole-protein formulas in post-operative course of pediatric patients regarding clinical outcome and better economically with shorter hospital stay.

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Low-phase angle in body composition measurements correlates with prolonged hospital stay in head and neck cancer patients

Acta Oto-Laryngologica ◽

10.1080/00016489.2019.1566779 ◽

2019 ◽

Vol 139 (4) ◽

pp. 383-387 ◽

Cited By ~ 4

Author(s):

Marie Lundberg ◽

Amy Dickinson ◽

Pia Nikander ◽

Helena Orell ◽

Antti Mäkitie

Keyword(s):

Body Composition ◽

Head And Neck Cancer ◽

Hospital Stay ◽

Head And Neck ◽

Cancer Patients ◽

Phase Angle ◽

Neck Cancer ◽

Prolonged Hospital Stay ◽

Prolonged Hospital ◽

Composition Measurements

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The relation between Malnutrition Universal Screening Tool (MUST), computed tomography–derived body composition, systemic inflammation, and clinical outcomes in patients undergoing surgery for colorectal cancer

American Journal of Clinical Nutrition ◽

10.1093/ajcn/nqz230 ◽

2019 ◽

Vol 110 (6) ◽

pp. 1327-1334 ◽

Cited By ~ 6

Author(s):

Arwa S Almasaudi ◽

Stephen T McSorley ◽

Ross D Dolan ◽

Christine A Edwards ◽

Donald C McMillan

Keyword(s):

Colorectal Cancer ◽

Computed Tomography ◽

Body Composition ◽

Nutritional Status ◽

Hospital Stay ◽

Clinical Outcomes ◽

Universal Screening ◽

Screening Tool ◽

Length Of Hospital Stay ◽

Malnutrition Universal Screening Tool

ABSTRACT Background Nutritional status is an important factor affecting a patient's clinical outcomes. Early identification of patients who are at risk of malnutrition is important to improve clinical outcomes and reduce health cost. The Malnutrition Universal Screening Tool (MUST) has been recommended as part of the routine nursing assessment for all patients at hospital admission. Objective The aim of this study was to examine the association between nutritional status (MUST), systemic inflammatory response (SIR), body composition, and clinical outcomes in patients undergoing surgery for colorectal cancer. Methods The malnutrition risk was examined using MUST in patients admitted for surgery for colorectal cancer between March 2013 and June 2016. Preoperative computed tomography scans were used to define the body composition. The presence of SIR was evidenced by the modified Glasgow prognostic score and the neutrophil to lymphocyte ratio. Postoperative complications, severity of complication, length of hospital stay, and mortality were considered as outcome measures. Results The study included 363 patients (199 males, 164 females); 21% of the patients presented with a medium or high nutritional risk. There were significant associations between MUST and subcutaneous adiposity (P < 0.001), visceral obesity (P < 0.001), and low skeletal muscle index (P < 0.001). No statistically significant association was identified between MUST score and presence of any complication or severity of complication. On multivariate analysis, MUST remained independently associated with the length of hospital stay (OR: 2.17; 95% CI: 1.45, 3.26; P < 0.001). Kaplan–Meier survival curves showed an increased number of deaths for patients at medium or high risk of malnutrition (P < 0.001). This association was found to be independent of other confounding factors (HR: 1.45; 95% CI: 1.06, 1.99; P = 0.020). Conclusions MUST score is an independent marker of risk in those undergoing surgery for colorectal cancer and should remain a key part of preoperative assessment.

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The Diagnosis of Viral Disease by Electron Microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010005398x ◽

1982 ◽

Vol 40 ◽

pp. 270-273

Author(s):

William B. McCombs ◽

Cameron E. McCoy

Keyword(s):

Electron Microscopy ◽

Hospital Stay ◽

Viral Infections ◽

Medical Profession ◽

Bacterial Pathogens ◽

Viral Disease ◽

Viral Pathogens ◽

Academic Interest ◽

The Past

Recent years have brought a reversal in the attitude of the medical profession toward the diagnosis of viral infections. Identification of bacterial pathogens was formerly thought to be faster than identification of viral pathogens. Viral identification was dismissed as being of academic interest or for confirming the presence of an epidemic, because the patient would recover or die before this could be accomplished. In the past 10 years, the goal of virologists has been to present the clinician with a viral identification in a matter of hours. This fast diagnosis has the potential for shortening the patient's hospital stay and preventing the administering of toxic and/or expensive antibiotics of no benefit to the patient.

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