Short Term Cardiovascular Effects and Oxidative Status of Calcium and Vitamin D Supplementation of Postmenopausal Hypertensive Blacks Women

2020 ◽  
Author(s):  
Keyword(s):  
Vitamin D ◽  
Cardiovascular Effects ◽  
Vitamin D Supplementation ◽  
Oxidative Status ◽  
Short Term

Short-term, low dose vitamin D supplementation in young patients with celiac disease

2020 ◽  
Vol 32 (5) ◽  
pp. 663-664
Author(s):  
Graziano Barera ◽  
Katia Maruca ◽  
Paola Sgaramella ◽  
Marina Di Stefano ◽  
Stefano Mora
Keyword(s):  
Vitamin D ◽  
Celiac Disease ◽  
Low Dose ◽  
Young Patients ◽  
Vitamin D Supplementation ◽  
Short Term

scholarly journals Vitamin D and Cardiovascular Risk: Which Implications in Children?

2020 ◽  
Vol 21 (10) ◽  
pp. 3536 ◽  
Author(s):  
Silvia Savastio ◽  
Erica Pozzi ◽  
Francesco Tagliaferri ◽  
Roberta Degrandi ◽  
Roberta Cinquatti ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cardiovascular Risk ◽  
Pediatric Patients ◽  
Cardiovascular Effects ◽  
Vitamin D Supplementation ◽  
Risk Markers ◽  
Randomized Controlled ◽  
Increased Risk ◽  
Vitamin D Levels ◽  
Lipid Parameters

Vitamin D (25OHD) pleiotropic effects are widely recognized and studied. Recently, vitamin D cardiovascular effects are gaining interest, especially in children, although the studies present conflicting data. Some randomized controlled trials (RCTs) have demonstrated that cardiovascular risk markers, such as lipid parameters, inflammation markers, blood pressure, and arterial stiffness, are unaffected by vitamin D supplementation. By contrast, other studies show that low vitamin D levels are associated with higher risk of cardiovascular disease (CVD) and mortality, and support that increased risk of these diseases occurs primarily in people with vitamin D deficiency. An update on these points in pediatric patients is certainly of interest to focus on possible benefits of its supplementation.

scholarly journals The short-term effect of vitamin D supplementation on the response to muscle and liver damages indices by exhaustive aerobic exercise in untrained men: a quasi-experimental study

2022 ◽  
Vol 14 (1) ◽  
Author(s):  
Vahid Parvizi Mastali ◽  
Rastegar Hoseini ◽  
Mohammad Azizi
Keyword(s):  
Vitamin D ◽  
Aerobic Exercise ◽  
Repeated Measures ◽  
Vitamin D Supplementation ◽  
T Test ◽  
Gamma Glutamyl Transferase ◽  
Fat Percentage ◽  
Short Term ◽  
Damage Indices ◽  
Glutamyl Transferase

Abstract Background Exercise-induced muscle damage typically caused by unaccustomed exercise results in pain, soreness, inflammation, and muscle and liver damages. Antioxidant supplementation might be a useful approach to reduce myocytes and hepatocytes damages. Therefore, the present study was conducted to investigate the effect of short-term vitamin D (Vit D) supplementation on the response to muscle and liver damages indices by Exhaustive Aerobic Exercise (EAE) in untrained men. Methods In this clinical trial, 24 untrained men were randomly divided into experimental (Exp; n = 12) and control (C; n = 12) groups. Exp received 2000 IU of Vit D daily for six weeks (42 days), while C daily received a lactose placebo with the same color, shape, and warmth percentage. Two bouts of EAE were performed on a treadmill before and after six weeks of supplementation. Anthropometric characteristics (Bodyweight (BW), height, Body Fat Percentage (BFP), Body Mass Index (BMI), waist to hip ratio (WHR)) were measured at the Pre 1 and Pre 2. Blood samples were taken to measure the Creatine Kinase (CK), Lactate Dehydrogenase (LDH), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Gamma-Glutamyl Transferase (GGT), Alkaline Phosphatase (ALP), and Vit D levels at four stages: Pre 1 (before the first EE session), Post 1 (after the first EE session), Pre 2 (before the second EE session), and Post 2 (after the second EE session). The data were analyzed using repeated-measures ANOVA, Bonferroni's post hoc test, independent t test, and dependent t-test at the significant level of P < 0.05 using SPSS version 26. Results The results show significant differences between Exp and C in alterations of BW (P = 0.039), BMI (P = 0.025), BFP (P = 0.043), and WHR (P = 0.035). The results showed that EAE increased muscle and liver damage indices and Vit D (P < 0.05). Compared with C, the results of the independent t-test showed significantly lower ALT (P = 0.001; P = 0.001), AST (P = 0.011; P = 0.001), GGT (P = 0.018; P = 0.001), and ALP (P = 0.001; P = 0.001); while significantly higher Vit D (P = 0.001, P = 0.001) in the Exp in both Pre 2 and Post 2; receptivity. The independent t test showed significantly lower ALT (P = 0.001; P = 0.001), AST (P = 0.011; P = 0.001), GGT (P = 0.018; P = 0.001), and ALP (P = 0.001; P = 0.001) and considerably greater Vit D (P = 0.001, P = 0.001) in the Exp in both Pre 2 and Post 2 compared to C. The results of an independent t test showed that LDH and CK levels in the Exp were significantly lower than those in the Post 2 (P = 0.001). Conclusions Short-term Vit D supplementation could prevent myocytes and hepatocytes damage induced by EAE.

Short-term Effects of Calcium and Vitamin D Supplementation in Postmenopausal Hypertensive Patients in sub-Saharan Africa: A Double Blinded Randomized Controlled Trial

2021 ◽  
Vol 1 (3) ◽  
pp. 59-64
Author(s):  
Chris Nadège Nganou-Gnindjio ◽  
Vicky Jocelyne Ama Moor ◽  
Constant Anatole Pieme ◽  
Guy Sadeu Wafeu ◽  
Ingrid Ngandjeu Kamtchoum ◽  
...  
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Sub Saharan Africa ◽  
Short Term ◽  
Hypertensive Patients ◽  
Randomized Controlled ◽  
Sub Saharan ◽  
Double Blinded

Effect of daily Vitamin D3 Supplementation on Muscle Health: An Individual Participant Meta-Analysis

2022 ◽  
Author(s):  
Lise Sofie Bislev ◽  
Louise Wamberg ◽  
Lars Rolighed ◽  
Diana Grove-Laugesen ◽  
Lars Rejnmark
Keyword(s):  
Vitamin D ◽  
Muscle Strength ◽  
Beneficial Effect ◽  
Vitamin D3 ◽  
Knee Flexion ◽  
Vitamin D Supplementation ◽  
Short Term ◽  
Individual Participant ◽  
Muscle Health ◽  
Isometric Muscle

Abstract Background The role of vitamin D on muscle health is debated. Methods An individual participant metanalysis of four randomized placebo-controlled trials, investigating short term (three to nine months) effects of vitamin D3 in moderate (2800 IU) to high (7000 IU) daily oral doses on muscle health and quality of life (QoL). Inclusion criteria were either obesity (N=52), newly diagnosed primary hyperparathyroidism (N=41), Graves’ disease (N=86) or secondary hyperparathyroidism (N=81). Results Overall (N=260) as well as in a subgroup analysis including only vitamin D insufficient (25(OH)D&lt; 50 nmol/L) individuals (N=176), vitamin D supplementation did not affect measures of muscle health (isometric muscle strength, Timed Up and Go test, Chair Rising Test, body composition, and balance) or QoL. However, a beneficial effect was present on QoL (physical component score) in vitamin D deficient (25(OH)D≤ 25 nmol/L) individuals (N=34). Overall, relative changes in 25(OH)D inversely affected maximum muscle strength in a dose response manner. Stratified into BMI &lt;/≥ 30 kg/m 2, vitamin D supplementation had divergent effects on isometric muscle strength, with beneficial effects in obese individuals (N=93) at knee flexion 90° (p=0.04), and adverse effects in non-obese individuals (N=167) at handgrip (p=0.02), knee extension 60° (p=0.03) and knee flexion 60° (p&lt;0.01). Conclusion Overall, short-term treatment with moderate to high daily doses of vitamin D did not affect muscle health or QoL. A potential beneficial effect was present on muscle strength in severe obese individuals and on QoL in vitamin D deficient individuals. Subgroup analyses however suggested negative effects of large relative increases in p-25(OH)D.

Sign in / Sign up

Export Citation Format

Share Document