scholarly journals EFFECTS OF COLLAPSING CAVITATION ON HIFU-EXPOSED BIOLOGICAL OBJECTS

2021 ◽  
Vol 3 (10(74)) ◽  
pp. 22-25
Author(s):  
V. Gryzunov ◽  
A. Zaycev ◽  
Yu. Kim ◽  
D. Tkhai
Keyword(s):  
Temperature Gradient ◽  
Thermal Ablation ◽  
Thermal Field ◽  
Local Heating ◽  
Ablation Zone ◽  
Mechanical Destruction ◽  
Biological Objects ◽  
Mechanical Component ◽  
Cavitation Bubbles

Therapeutic significance in the studies of HIFU-induced effects of is attached to the local heating of tissues, but the role of the mechanical component caused by non-stationary cavitation is practically not taken into account. Calculations show that the temperature inside cavitation bubbles can differ significantly from the temperature in the thermal ablation zone, and the developing temperature gradient can change the formation of the thermal field. Collapsing bubbles can cause mechanical destruction of tissues.

Role of contrast enhanced ultrasound (CEUS) in evaluation of thermal ablation zone

2016 ◽  
Vol 27 (3) ◽  
pp. S82-S83
Author(s):  
I. Lekht ◽  
M. Gulati ◽  
M. Nayyar ◽  
M. Katz ◽  
R. Ter-Oganesyan ◽  
...  
Keyword(s):  
Thermal Ablation ◽  
Ablation Zone ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

Role of contrast-enhanced ultrasound (CEUS) in evaluation of thermal ablation zone

2016 ◽  
Vol 41 (8) ◽  
pp. 1511-1521 ◽  
Author(s):  
Ilya Lekht ◽  
Mittul Gulati ◽  
Megha Nayyar ◽  
Michael D. Katz ◽  
Ramon Ter-Oganesyan ◽  
...  
Keyword(s):  
Thermal Ablation ◽  
Ablation Zone ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

scholarly journals Role of Thermal Ablation in Colorectal Cancer Lung Metastases

Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 908
Author(s):  
Alexandre Delpla ◽  
Thierry de Baere ◽  
Eloi Varin ◽  
Frederic Deschamps ◽  
Charles Roux ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Factors ◽  
Thermal Ablation ◽  
Medical Oncology ◽  
Pulmonary Metastases ◽  
Lung Metastases ◽  
Stereotactic Ablative Radiotherapy ◽  
Chest Drainage ◽  
Results Of Surgery

Background: Consensus guidelines of the European Society for Medical Oncology (ESMO) (2016) provided recommendations for the management of lung metastases. Thermal ablation appears as a tool in the management of these secondary pulmonary lesions, in the same manner as surgical resection or stereotactic ablative radiotherapy (SABR). Methods: Indications, technical considerations, oncological outcomes such as survival (OS) or local control (LC), prognostic factors and complications of thermal ablation in colorectal cancer lung metastases were reviewed and put into perspective with results of surgery and SABR. Results: LC rates varied from 62 to 91%, with size of the metastasis (<2 cm), proximity to the bronchi or vessels, and size of ablation margins (>5 mm) as predictive factors of LC. Median OS varied between 33 and 68 months. Pulmonary free disease interval <12 months, positive carcinoembryonic antigen, absence of neoadjuvant chemotherapy and uncontrolled extra-pulmonary metastases were poor prognostic factors for OS. While chest drainage for less than 48 h was required in 13 to 47% of treatments, major complications were rare. Conclusions: Thermal ablation of a selected subpopulation of patients with colorectal cancer lung metastases is safe and can provide excellent LC and delay systemic chemotherapy.

scholarly journals Role of thermal field in entanglement harvesting between two accelerated Unruh-DeWitt detectors

2021 ◽  
Vol 2021 (7) ◽  
Author(s):  
Dipankar Barman ◽  
Subhajit Barman ◽  
Bibhas Ranjan Majhi
Keyword(s):  
Mutual Information ◽  
Critical Point ◽  
Thermal Field ◽  
Narrow Range ◽  
Critical Value ◽  
Critical Values ◽  
Parallel Motion ◽  
Field Temperature ◽  
The Right

Abstract We investigate the effects of field temperature T(f) on the entanglement harvesting between two uniformly accelerated detectors. For their parallel motion, the thermal nature of fields does not produce any entanglement, and therefore, the outcome is the same as the non-thermal situation. On the contrary, T(f) affects entanglement harvesting when the detectors are in anti-parallel motion, i.e., when detectors A and B are in the right and left Rindler wedges, respectively. While for T(f) = 0 entanglement harvesting is possible for all values of A’s acceleration aA, in the presence of temperature, it is possible only within a narrow range of aA. In (1 + 1) dimensions, the range starts from specific values and extends to infinity, and as we increase T(f), the minimum required value of aA for entanglement harvesting increases. Moreover, above a critical value aA = ac harvesting increases as we increase T(f), which is just opposite to the accelerations below it. There are several critical values in (1 + 3) dimensions when they are in different accelerations. Contrary to the single range in (1 + 1) dimensions, here harvesting is possible within several discrete ranges of aA. Interestingly, for equal accelerations, one has a single critical point, with nature quite similar to (1 + 1) dimensional results. We also discuss the dependence of mutual information among these detectors on aA and T(f).

The Role of Percutaneous Image-Guided Thermal Ablation for the Treatment of Pulmonary Malignancies

2017 ◽  
Vol 209 (4) ◽  
pp. 740-751 ◽  
Author(s):  
Samdeep K. Mouli ◽  
Ieva Kurilova ◽  
Constantinos T. Sofocleous ◽  
Robert J. Lewandowski
Keyword(s):  
Thermal Ablation ◽  
Image Guided

scholarly journals Orbital forcing and role of the latitudinal insolation/temperature gradient

2008 ◽  
Vol 32 (2-3) ◽  
pp. 143-165 ◽  
Author(s):  
Basil A. S. Davis ◽  
Simon Brewer
Keyword(s):  
Temperature Gradient ◽  
Orbital Forcing

Percutaneous liquid ablation agent for tumor treatment and drug delivery

2021 ◽  
Vol 13 (580) ◽  
pp. eabe3889
Author(s):  
Hassan Albadawi ◽  
Zefu Zhang ◽  
Izzet Altun ◽  
Jingjie Hu ◽  
Leila Jamal ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Ionic Liquid ◽  
Liver Tumor ◽  
Thermal Ablation ◽  
Liver Tumors ◽  
Low Cost ◽  
Drug Distribution ◽  
Tumor Model ◽  
Ablation Zone ◽  
Synergistic Cytotoxicity

Percutaneous locoregional therapies (LRTs), such as thermal ablation, are performed to limit the progression of hepatocellular carcinoma (HCC) and offer a bridge for patients waiting for liver transplantation. However, physiological challenges related to tumor location, size, and existence of multiple lesions as well as safety concerns related to potential thermal injury to adjacent tissues may preclude the use of thermal ablation or lead to its failure. Here, we showed a successful injection of an ionic liquid into tissue under image guidance, ablation of tumors in response to the injected ionic liquid, and persistence (28 days) of coinjected chemotherapy with the ionic liquid in the ablation zone. In a rat HCC model, the rabbit VX2 liver tumor model, and 12 human resected tumors, injection of the ionic liquid led to consistent tumor ablation. Combining the ionic liquid with the chemotherapy agent, doxorubicin, resulted in synergistic cytotoxicity when tested with cultured HCC cells and uniform drug distribution throughout the ablation zone when percutaneously injected into liver tumors in the rabbit liver tumor model. Because this ionic liquid preparation is simple to use, is efficacious, and has a low cost, we propose that this new LRT may bridge more patients to liver transplantation.

scholarly journals Lung Ablation: Indications and Techniques

2019 ◽  
Vol 36 (03) ◽  
pp. 163-175 ◽  
Author(s):  
Bashir Akhavan Tafti ◽  
Scott Genshaft ◽  
Robert Suh ◽  
Fereidoun Abtin
Keyword(s):  
Thermal Ablation ◽  
Microwave Ablation ◽  
Local Therapy ◽  
Initial Report ◽  
Image Guided

AbstractLung ablation is ever more recognized since its initial report and use almost two decades ago. With technological advancements in thermal modalities, particularly microwave ablation and cryoablation, better identification of the cohort of patients who best benefit from ablation, and understanding the role of imaging after ablation, image-guided thermal ablation for primary and secondary pulmonary malignancies is increasingly recognized and accepted as a cogent form of local therapy.

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