scholarly journals COMPARATIVE ANATOMY OF THE STRUCTURE OF THE VILLISIAN CIRCLE IN PERSONS WITH CEREBRAL CIRCULATION DISORDERS AND WITHOUT SIGNS OF PATHOLOGY

2021 ◽  
Vol 2 (2(83)) ◽  
pp. 23-25
Author(s):  
A. Salmina ◽  
V. Levantsevich ◽  
D. Boris ◽  
T. Semak
Keyword(s):  
Cerebral Circulation ◽  
Comparative Anatomy ◽  
Cerebral Arteries ◽  
Age Groups ◽  
Classical Type ◽  
Anterior Communicating Artery ◽  
Collateral Blood Flow ◽  
Cerebrovascular Pathology ◽  
Cerebral Circulation Disorders ◽  
The Brain

The study is devoted to the study of the anatomy of the Willis circle of people with and without cerebral circulation pathology. We studied 243 angiograms (men and women of different age groups from 18 to 72 years old). Of these, 120 patients had no signs of cerebrovascular pathology, 123 patients had various kinds of cerebral circulation disorders. Only in 32% of cases, when studying 120 MR-angiograms of persons without cerebral circulation disorders, a classical type of structure of the arterial bed was revealed. In 68% of the subjects, structural anomalies were found, namely: 23% hypoplasia of the anterior communicating artery, 21% aplasia or hypoplasia of one of the posterior communicating arteries, 17% combination of aplasia of the anterior communicating arteries and aplasia of one of the posterior communicating arteries, 4% aplasia of the anterior and both posterior connecting arteries, 3% parietal contact of both anterior cerebral arteries. A study of the Willis circle of patients with cerebrovascular pathology revealed: 2% have a classic variant of the structure, 53% have aplasia of one of the posterior communicating arteries, aplasia of both posterior communicating arteries 26%, 19% a variant in which aplasia of the anterior and posterior communicating arteries is combined. Based on the foregoing, the classical type of structure of the arterial circle of the brain is the most optimal option for ensuring collateral blood flow.

scholarly journals Treatment of arterial aneurysms of anterior cerebral circulation

2002 ◽  
Vol 59 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Zoran Roganovic ◽  
Goran Pavlicevic ◽  
Radenko Tadic
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Conservative Treatment ◽  
Cerebral Circulation ◽  
Cerebral Arteries ◽  
Clinical State ◽  
Anterior Communicating Artery ◽  
Aneurysmal Rupture ◽  
Middle Cerebral Arteries ◽  
Arterial Aneurysms

Objectives: To analyze the outcome of either surgical or conservative treatment of patients with aneurysms on cerebral arteries. Design Retrospective study on 114 patients (89 operated and 25 not operated). Methods: Clinical state was graded from 0 to V, according to Hunt & Hess (HHG), and the treatment outcome was defined as favorable or poor, according to the modified Glasgow Outcome Score. The outcome was correlated with the type of treatment (operative or conservative), clinical state and aneurysmal localization. Results: Aneurysm was localized mostly on the anterior communicating (33.6%) and middle cerebral arteries (32.8%) and the patients were mostly in HHG II or III (34.4% and 25.2%). HHG after the aneurysmal rupture did not depend on the aneurysmal location (p>0.05). Favorable treatment outcome was noted: in 74.1% of all operated and in 60% of all conservatively treated patients (p>0.05)( in 81.6% of operated and in 33.3% of not operated patients with HHG=II-III (p<0.01)( in 78.8% of aneurysms of the middle cerebral artery and in 66.7% of those of the anterior communicating artery (p>0.05)( in 73.1% of patients with HHG=III and in 25% of patients with HHG=IV (p<0.01).Conclusions: Clinical state after the aneurysmal rupture did not depend on its localization. Results were better after the surgical, than after the conservative treatment. Outcome after the surgery depended on the clinical state of the patient, but not on the aneurysmal localization.

Contribution of lipoprotein(a) to cardiovascular risk in patients under 40 years of age after acute myocardial infarction or acute cerebral circulation disorder

2016 ◽  
Vol 94 (3) ◽  
pp. 194-199 ◽  
Author(s):  
Viktoriya A. Korneva ◽  
T. Yu. Kuznetsova ◽  
A. S. Novitskaya ◽  
A. N. Malygin ◽  
T. A. Guseva ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiovascular Risk ◽  
Arterial Hypertension ◽  
Cerebral Circulation ◽  
Age Groups ◽  
Middle Aged ◽  
Vascular Events ◽  
Lipoprotein A ◽  
Cerebral Circulation Disorders

Aim. To evaluate the importance of lipoprotein(a) for the evaluation of cardiovascular risk in patient under 40 years of age after acute myocardial infarction or acute cerebral circulation disorder. Materials and methods. We analysed the data from two departments of the Regional Vascular Centre for 2013-2015 including 90 case histories of patients of different age (mean 57.8±3.4 yr) and studied standard risk factors, such as age, sex, smoking habits, dyslipidemia, aggravated heredity, arterial hypertension (AH), obesity. Standard examination of 7 patients under 40 years of age was supplemented by measuring lipoprotein(a) by the immunoturbodimetric method regarding the levels over J. 3 g/l as abnormally elevated. Results. The study group was dominated by young and middle-aged men (85.2 and 84% respectively). The key riskfactors were increased LDLP level (88%) and smoking (70%) in patients under the age of 40 and AH in middle-aged men (100%, p<0.004). Arterial hypertension was also diagnosed in 59% of the younger subjects. Increased LDLP levels most frequently occurred in senior patients (90%). The group ofpatients under 40 yr included 15% of those having a single risk factor. In this group, 22% of the patients were at high risk calculated prior to the development of vascular events, 58% at moderate and 20% at low risk. 42.8% of the patients had elevated lipoprotein(a) levels. Conclusion. Based on the relative risk scoring scale, 22% of the patients under 40 years of age were at risk of myocardial infarction or cerebral circulation disorders prior to the development of vascular events. However, these patients like those of other age groups frequently had traditional riskfactors, such as smoking (67.5%), AH and dyslipidemia (66.6% each). Total cholesterol was elevated only in 47.6% of the patients while LDLP and LP(a) in 92 and 42.8% respectively.

The recurrent artery of Heubner: Otto Heubner's description of the artery and his influence on pediatrics in Germany

2000 ◽  
Vol 93 (6) ◽  
pp. 1084-1088 ◽  
Author(s):  
Raymond I. Haroun ◽  
Daniele Rigamonti ◽  
Rafael J. Tamargo
Keyword(s):  
Internal Medicine ◽  
Energy Metabolism ◽  
Cerebral Arteries ◽  
Early Research ◽  
Anterior Communicating Artery ◽  
Anatomical Studies ◽  
Content Type ◽  
Morphological Studies ◽  
The Brain ◽  
Fine Print

✓ Although the recurrent artery of Heubner is one of the best known cerebral arteries, little has been written in the neurosurgical or anatomical literature about its discovery. The artery is of primary importance to cerebrovascular surgeons, who identify it during clipping of anterior communicating artery aneurysms. Johann Otto Leonhardt Heubner (1843–1926), who described this artery in 1872, is better known as the father of German pediatrics. He was appointed to the first professorship in Germany exclusively devoted to pediatrics at the Charité Children's Clinic of Berlin University. Although he initially studied internal medicine in Leipzig under Carl Reinhold August Wunderlich and Ernst Leberecht Wagner, his early research involved anatomical studies of the circulation of the brain, from which he described syphilitic endarteritis (Heubner's disease). Finding morphological studies inconclusive, he turned to more physiological experiments. Together with the physiologist Max Rubner, Heubner performed important studies on energy metabolism in infancy, creating the notion of the nutrition quotient. In this article the authors review Heubner's life and scientific discoveries.

Vascular Headaches and Cerebral Circulation: An Overview

Cephalalgia ◽  
1985 ◽  
Vol 5 (2_suppl) ◽  
pp. 9-15 ◽  
Author(s):  
Alessandro Agnoli ◽  
Milena De Marinis
Keyword(s):  
Locus Coeruleus ◽  
Trigeminal Ganglion ◽  
Cerebral Circulation ◽  
Cerebral Arteries ◽  
Vascular Changes ◽  
Vasoactive Peptides ◽  
Vasodilator Activity ◽  
Vascular Origin ◽  
Nociceptive Pathway ◽  
The Brain

complex network of neurotransmission systems underlies the control of the cerebral circulation. Classical neurotransmitters, vasoactive peptides and receptors have been found in cerebral arteries. Central and peripheral structures are also probably involved in the neurogenic control of the cerebral circulation. Vascular and neurotransmission changes reported in vascular headaches suggest that an alteration of the neurogenic control of the brain circulation may be implicated in vascular headaches. In particular, locus coeruleus, which may control the intracerebral adrenergic pathway, can induce vascular changes similar to those of migraine. Moreover, the trigeminal ganglion, which may induce the release of substance P, can change the extracranial and intracranial vasodilator activity. The vascular theory of migraine, proposed by Wolff, is re-evaluated on the grounds of a possible mediation of the vascular responses by neurotransmitters. It is hypothesized that a deficient modulation by enkephalins may cause alterations of locus coeruleus and/or trigeminal ganglion. The problem of pain in vascular headaches is also considered: whether it is of vascular origin or whether it is due to a dysfunction of the central nociceptive pathway. Knowledge of the neurogenic control of the cerebral circulation may be useful in understanding some pathogenetic mechanisms of vascular headaches.

scholarly journals The Cerebral Circulation During Pregnancy: Adapting to Preserve Normalcy

Physiology ◽  
2015 ◽  
Vol 30 (2) ◽  
pp. 139-147 ◽  
Author(s):  
Abbie C. Johnson ◽  
Marilyn J. Cipolla
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Blood Brain Barrier ◽  
Cerebral Circulation ◽  
Cerebral Arteries ◽  
Structure And Function ◽  
Cerebral Blood Flow Autoregulation ◽  
And Function ◽  
The Brain ◽  
Brain Homeostasis

The adaptation of the brain and cerebral circulation to pregnancy are unique compared with other organs and circulatory systems, ultimately functioning to maintain brain homeostasis. In this review, the effect of pregnancy on critical functions of the cerebral circulation is discussed, including changes occurring at the endothelium and blood-brain barrier, and changes in the structure and function of cerebral arteries and arterioles, hemodynamics, and cerebral blood flow autoregulation.

Brain MRI-findings in Ph - negative myeloproliferative disorders

2019 ◽  
Vol 91 (7) ◽  
pp. 29-34 ◽  
Author(s):  
M M Tanashyan ◽  
A L Melikyan ◽  
P I Kuznetsova ◽  
A A Raskurazhev ◽  
A A Shabalina ◽  
...  
Keyword(s):  
Cerebrovascular Disease ◽  
Sinus Thrombosis ◽  
Cerebral Arteries ◽  
Brain Mri ◽  
Myeloproliferative Disorders ◽  
Cerebral Venous Sinus Thrombosis ◽  
Mri Findings ◽  
Cerebral Lesions ◽  
Cerebrovascular Pathology ◽  
Underlying Mechanisms

Myeloproliferative disorders (MPD) are accompanied by a high proportion of thrombotic complications, which may lead to cerebrovascular disease (CVD). Aim. To describe MRI-findings in patients with Ph - negative MPD and evaluate any cerebrovascular disease. Materials and methods. We included 104 patients with Ph - negative MPD (age varied between 20 and 58) with clinical correlates of cerebrovascular pathology. Results. Brain MRI showed post - stroke lesions in 20% of patients (7 hemispheric infarcts due to thrombotic occlusion of one of the large cerebral arteries, 14 - cortical infarcts). 37 patients (36%) had vascular cerebral lesions. Cerebral venous sinus thrombosis occurred in 5 patients - in 7% (n=3) of patients with polycythemia vera and 5% (n=2) - in patients with essential thrombocythemia. The incidence of vascular cerebral lesions was associated with higher levels of the following: erythrocyte, platelet count, fibrinogen, and with the decrease in fibrinolytic activity, as well. Conclusion. The pioneering results of the study include the description and analysis of brain MRI-findings in patients with Ph - negative MPD. The underlying mechanisms of cerebrovascular pathology in these patients are associated with certain blood alterations (particularly, hemorheology) which present a major risk factor.

Macroscopic Anatomy and Brain Vascularization in the Greater Rhea (Rhea americana americana)

2018 ◽  
Vol 46 (1) ◽  
Author(s):  
Herson Da Silva Costa ◽  
Hélio Norberto De Araújo Júnior ◽  
Ferdinando Vinícius Fernandes Bezerra ◽  
Carlos Eduardo Vale Rebouças ◽  
Danilo José Ayres De Menezes ◽  
...  
Keyword(s):  
Basilar Artery ◽  
Carotid Arteries ◽  
Vascular System ◽  
Cerebral Arteries ◽  
Cervical Region ◽  
Type I ◽  
Macroscopic Anatomy ◽  
Rhea Americana ◽  
Vascular Type ◽  
The Brain

 Background: The Rhea americana americana is a wild bird belonging to the group of Ratites, and is important from the scientific point of view given their adaptability to captivity. Considering that information about its morphology is important for the viability of domesticating the species, the aim of this study was to macroscopically identify the brain regions, as well as the cerebral arteries and the cerebral arterial circuit in order to establish the cerebral vascular pattern and systematization.Materials, Methods & Results: Twenty one brains from young and adult Greater Rheas of both sexes were used from animals that had died due to natural causes and were then kept in a freezer. The specimens were thawed and incised in the cervical region to allow exposure of the left common carotid artery, which was cannulated. The vascular system was rinsed with 0.9% saline solution, then perfused with latex Neoprene 650 stained with red pigment. The animals were subsequently fixed in 3.7% aqueous formaldehyde solution for 72 h, and then they were dissected by removing the bones from the skull cap. The brains were analyzed, and the structures were identified, photographed, schematized and denominated. Morphometric measurements were performed on the basilar and cerebellar ventral caudal arteries, recording the values of length and width in millimeters with the aid of a digital caliper. The brain was divided into: telencephalon, diencephalon, brainstem and cerebellum; while externally, the observed structures are: olfactory bulbs, optical lobes, optic nerves, optic chiasm, pituitary and pineal glands. Vascularization was performed by the following arteries: ventral spinal artery, basilar artery, ventricular cerebellar arteries, medium ventricular cerebellar arteries, caudal branches of the carotid arteries of the brain, ventral mesencephalic artery, cerebral caudal arteries, rostral branches of the carotid arteries of the brain, middle cerebral arteries, cerebroethmoidal arteries, rostral intercerebral anastomosis, rostral cerebral arteries, ethmoidal arteries, internal ophthalmic arteries, inter-hemispheric artery, pituitary arteries, dorsal mesencephalic tectal arteries, dorsal cerebellar arteries, occipital, pineal and dorsal hemispherical branches. The cerebral arterial circuit was both caudally and rostrally closed in 100.0% of the samples, being composed of the arteries: basilar artery, caudal branches of the carotid brain, rostral branches of the brain carotid, cerebroethmoidal arteries and rostral intercerebral anastomosis.Discussion: Encephalon classification regarding the presence or absence of gyri is a characteristic associated to evolution­ary aspects among vertebrates, being respectively considered as lisencephalon or girencecephalus when it presents or does not present convolutions. In Greater Rheas, the telencephalon was quite developed, with a relatively rounded shape and the absence of sulci and convolutions in the cortex, which allowed it to be classified as a lisencephalon. Such findings resemble those described for the ostrich and in a comparative study involving kiwis, emus, owls and pigeons, although different sizes and forms of telencephalon development were observed in the latter. Regarding the cerebral arterial circuit, this structure in Rheas was complete and both caudally and rostrally closed in 100.0% of the specimens. Our findings differ from those ob­served for ostriches, in which a rostrally open behavior has been described, while it is caudally closed in 20.0% of cases and opened in 80.0%. Regarding the vascular type of the brain, in the Rhea it was observed that there was only contribution of the carotid system, similar to that found for birds such as ostriches and turkeys which confer a type I encephalic vascularization.Keywords: arteries, brain, arterial circuit, morphometry, ratites.

Aetiologies and anatomy of confabulation

2017 ◽  
Author(s):  
Armin Schnider
Keyword(s):  
Brain Damage ◽  
Limbic Encephalitis ◽  
Artery Aneurysm ◽  
Anterior Communicating Artery ◽  
Brain Areas ◽  
Anatomical Basis ◽  
Korsakoff Syndrome ◽  
Hypoxic Brain ◽  
Degenerative Dementia ◽  
The Brain

What diseases cause confabulations and which are the brain areas whose damage is responsible? This chapter reviews the causes, both historic and present, of confabulations and deduces the anatomo-clinical relationships for the four forms of confabulation in the following disorders: alcoholic Korsakoff syndrome, traumatic brain injury, rupture of an anterior communicating artery aneurysm, posterior circulation stroke, herpes and limbic encephalitis, hypoxic brain damage, degenerative dementia, tumours, schizophrenia, and syphilis. Overall, clinically relevant confabulation is rare. Some aetiologies have become more important over time, others have virtually disappeared. While confabulations seem to be more frequent after anterior brain damage, only one form has a distinct anatomical basis.

scholarly journals Quantifying asymmetry of anterior cerebral arteries as a predictor of anterior communicating artery complex aneurysm

2020 ◽  
Vol 2 (1) ◽  
pp. e000059
Author(s):  
Arjun Burlakoti ◽  
Jaliya Kumaratilake ◽  
David J Taylor ◽  
Maciej Henneberg
Keyword(s):  
Significant Contribution ◽  
Anterior Cerebral Artery ◽  
Cerebral Arteries ◽  
South Australia ◽  
General Information ◽  
Anterior Communicating Artery ◽  
Cross Sectional ◽  
Complex Aneurysm ◽  
Measured Position ◽  
Cerebral Computed Tomography

ObjectivesThe aim of this study was to establish an anatomical index for early prediction of the risk of development of aneurysms in anterior communicating arterial complex (AcomAC). The asymmetric diameter of one anterior cerebral artery (ACA) to other could alter haemodynamics and may contribute to formation of aneurysms in AcomAC and be a reliable predictor of the risk of development of aneurysms.Design and settingThis is a retrospective, observational and quantitative study, which used cerebral computed tomography angiography (CCTA) scans in South Australia.ParticipantsCCTA scans of 166 adult patients of both sexes were studied.Main outcome measuresThe internal diameters of the proximal segments of ACAs (A1s) were measured. Position and presence or absence of aneurysms in AcomAC were determined. The ratio of A1 diameters was taken as a measure of A1 asymmetry.ResultsThe ratio of diameters of A1s correlated with the occurrence of AcomAC aneurysms. The risk of development of aneurysms in AcomAC was much greater (80%, OR=47.3) when one A1 segment’s radius was at least 50% larger (ie, 2.25 times cross-sectional area) than the other.ConclusionThe general information on asymmetric A1 has been published previously. The present findings have significant contribution since the A1s asymmetry ratios have been categorised in ascending order and matched with the presence of AcomAC aneurysms. The asymmetry ratio of the A1 is a good predictor for the development of AcomAC aneurysms. Reconstruction of the asymmetric A1 could be done if the technology gets advanced.

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