scholarly journals BONE PROPERTIES AND BLOOD BONE METABOLISM MARKERS IN RESPONSE TO EXERCISES AND HONEY SUPPLEMENTATION: A CONTEMPORARY REVIEW

2018 ◽  
Vol 2 (2) ◽  
pp. 68-74
Author(s):  
Foong Kiew Ooi

Osteoporosis is a disease characterised by a loss of bone mass and the structure deterioration of bone tissue, resulting in bone fragility and fractures. This disease imposes major burden on the health economy and being recognised as one of the major public health problems worldwide. To date, many strategies have been developed with the aim of preventing bone loss and increasing bone mass, these include involvement in physical activity programmes and through appropriate nutritional intake. Honey contains mainly carbohydrates, vitamins and minerals such as calcium, phosphorus and magnesium, which are believed to be important for enhancing bone health. This article discusses the findings of several research studies on bone properties and blood bone metabolism markers in response to combined exercises and honey supplementation in animals and humans, which have been carried out by the bone and exercise research team of Universiti Sains Malaysia.

2010 ◽  
Vol 54 (2) ◽  
pp. 179-185 ◽  
Author(s):  
Bárbara Santarosa Emo Peters ◽  
Lígia Araújo Martini

Osteoporosis is a global health problem characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture. Nutrition plays a critical role in reducing the risk of osteoporosis through its effect on all of these fragility factors, especially on the development and maintenance of bone mass. An adequate calcium, vitamin D and protein intake resulted in reduced bone remodeling, better calcium retention, reduced age-related bone loss, and reduced fracture risk. Recent evidence indicates that a healthy dietary pattern including dairy products (mainly fat free), fruit and vegetables and adequate amounts of meat, fish and poultry is positively related to bone health. Furthermore, mineral and vitamin supplementation should be closely monitored by health professionals since it could have adverse effects and be insufficient to ensure optimal protection of bone health.


2008 ◽  
Vol 100 (4) ◽  
pp. 852-858 ◽  
Author(s):  
Marieke J. H. van Summeren ◽  
Silvia C. C. M. van Coeverden ◽  
Leon J. Schurgers ◽  
Lavienja A. J. L. M. Braam ◽  
Florence Noirt ◽  
...  

In adult bone, vitamin K contributes to bone health, probably through its role as co-factor in the carboxylation of osteocalcin. In children, the significance of vitamin K in bone-mass acquisition is less well known. The objective of this longitudinal study was to determine whether biochemical indicators of vitamin K status are related to (gains in) bone mineral content (BMC) and markers of bone metabolism in peripubertal children. In 307 healthy children (mean age 11·2 years), BMC of the total body, lumbar spine and femoral neck was determined at baseline and 2 years later. Vitamin K status (ratio of undercarboxylated (ucOC) to carboxylated (cOC) fractions of osteocalcin; UCR) was also measured at both time points. Markers of bone metabolism, sex steroids, vitamin D status and growth hormones were measured at baseline only. Large variations in the levels of the UCR were found at both time-points, indicating a substantial interindividual difference in vitamin K status. Improvement of vitamin K status over 2 years (n281 children) was associated with a marked increase in total body BMC (r− 49·1,P < 0·001). The UCR was associated with pubertal stage, markers of bone metabolism, sex hormones and vitamin D status. A better vitamin K status was associated with more pronounced increase in bone mass in healthy peripubertal children. In order to determine the significance of these findings for childhood bone health, additional paediatric studies are needed.


2002 ◽  
Vol 57 (1) ◽  
pp. 107-116 ◽  
Author(s):  
S. C. C. M. Van Coeverden ◽  
J. C. Netelenbos ◽  
C. M. De Ridder ◽  
J. C. Roos ◽  
C. Popp-Snijders ◽  
...  

2014 ◽  
Vol 58 (5) ◽  
pp. 478-483 ◽  
Author(s):  
Robert Güerri-Fernández ◽  
Judit Villar-García ◽  
Adolfo Díez-Pérez ◽  
Daniel Prieto-Alhambra

With the advent of high active antiretroviral therapy there was a significant improvement on HIV subjects survival. Thus, bone changes related to HIV became an important aspect of these individuals. HIV affects bone remodeling causing bone fragility. In addition, antiretroviral therapy may also negatively affect bone metabolism. Several studies describe an increased incidence of fractures in these patients when compared with controls without the disease. The European Society of AIDS (EACS), and other societies, have included guidance on management of osteoporosis in HIV-infected patients emphasizing the identification of patients with low bone mass. Supplementation of calcium and vitamin D and the use of alendronate in these individuals should be recommended on a case base.


2022 ◽  
Vol 2022 ◽  
pp. 1-9
Author(s):  
Shuang Han ◽  
Fang Gong ◽  
Yifeng Xue ◽  
Chunxin Wang ◽  
Xiaowei Qi

Serum P1NP, one of the important biomarkers for bone turnover, is commonly used for the prediction of bone fracture and the prognosis of osteoporosis after therapy. We developed a P1NP chemiluminescence assay and evaluated changes in bone metabolism markers in lung transplant patients. The screened 2 P1NP antibodies with constructed antigens and α-1 chain antigens expressed by the Corynebacterium glutamate expression system were applied into assay development. The assay performance was evaluated to examine the reliability. A normal Q-Q plot was used to establish male reference interval. Changes of bone metabolism markers before and after lung transplantation in 19 patients were evaluated. The linear factor R of P1NP reagent was greater than 0.99. The limit of detection was 3.32 ng/ml. The precision of the three batches of P1NP reagents was lower than 8%. Method comparison with Roche P1NP reagent showed that the correlation coefficient R2 was 0.91. In the monitoring of bone mass in a short time, bone metabolism markers can better indicate the change of bone mass, while the traditional bone mineral density detection is lagging behind the bone metabolism markers. P1NP and β-CrossLap to bone mass change in patients after lung transplantation, and P1NP and β-CrossLap are very good clinical markers for bone mass monitoring.


2006 ◽  
Vol 64 (6) ◽  
pp. 625-631 ◽  
Author(s):  
L. Terpstra ◽  
D. L. Knol ◽  
S. C. Van Coeverden ◽  
H. A. Delemarre-van de Waal

2006 ◽  
Vol 9 (3) ◽  
pp. 11-13
Author(s):  
T G Vasil'eva ◽  
O G Maksimova ◽  
E A Kochetkova

We investigated 130 healthy children and adolescences, its dates of dual-energy X-ray absorbtiometry, bone metabolism markers. The formation of bone mass peak, bone's mineralization in healthy children is depending on age, anthropometric status, sex, dietary with uneven activity in the different local of skeleton. The level of bone metabolism markers is depending on period of life, with maximal dates in patient's 12-14 yeas old. The level of osteopenic syndrome in healthy children consist 15,39%.


2010 ◽  
Vol 74 (5) ◽  
pp. 339-350 ◽  
Author(s):  
L. Gracia-Marco ◽  
G. Vicente-Rodríguez ◽  
J. Valtueña ◽  
J.P. Rey-López ◽  
A.E. Díaz Martínez ◽  
...  

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