Non-audiofacial morbidity after Gamma Knife surgery for vestibular schwannoma

2009 ◽  
Vol 27 (6) ◽  
pp. E4 ◽  
Author(s):  
Michael E. Sughrue ◽  
Isaac Yang ◽  
Seunggu J. Han ◽  
Derick Aranda ◽  
Ari J. Kane ◽  
...  

Object While many studies have been published outlining morbidity following radiosurgical treatment of vestibular schwannomas, significant interpractitioner and institutional variability still exists. For this reason, the authors conducted a systematic review of the literature for non-audiofacial-related morbidity after the treatment of vestibular schwannoma with radiosurgery. Methods The authors performed a comprehensive search of the English-language literature to identify studies that published outcome data of patients undergoing radiosurgery treatment for vestibular schwannomas. In total, 254 articles were found that described more than 50,000 patients and were analyzed for satisfying the authors' inclusion criteria. Patients from these studies were then separated into 2 cohorts based on the marginal dose of radiation: ≤ 13 Gy and > 13 Gy. All tumors included in this study were < 25 mm in their largest diameter. Results A total of 63 articles met the criteria of the established search protocol, which combined for a total of 5631 patients. Patients receiving > 13 Gy were significantly more likely to develop trigeminal nerve neuropathy than those receiving < 13 Gy (p < 0.001). While we found no relationship between radiation dose and the rate of developing hydrocephalus (0.6% for both cohorts), patients with hydrocephalus who received doses > 13 Gy appeared to have a higher rate of symptomatic hydrocephalus requiring shunt treatment (96% [> 13 Gy] vs 56% [≤ 13 Gy], p < 0.001). The rates of vertigo or balance disturbance (1.1% [> 13 Gy] vs 1.8% [≤ 13 Gy], p = 0.001) and tinnitus (0.1% [> 13 Gy] vs 0.7% [≤ 13 Gy], p = 0.001) were significantly higher in the lower dose cohort than those in the higher dose cohort. Conclusions The results of our review of the literature provide a systematic summary of the published rates of nonaudiofacial morbidity following radiosurgery for vestibular schwannoma.

1997 ◽  
Vol 5 (2) ◽  
pp. 118-122
Author(s):  
Hubert YM Chao ◽  
Ralph T Manktelow

Pectoralis major rupture is uncommon. Injury usually occurs from sporting activities. The incidence and management of pectoralis major rupture is not well known, despite 74 case reports in the English language literature over the past 34 years. Two cases of chronic pectoralis ruptures and their successful surgical management are described. A review of the literature shows that most injuries occur at the humeral insertion, and most are complete ruptures. Distinguishing between complete and partial ruptures is important. Complete ruptures are best treated surgically in the acute situation. When chronic complete ruptures present, surgical repair yields fair to good results. Acute partial ruptures can be effectively managed conservatively or with surgery. Chronic partial ruptures can be managed surgically with good results, following unsatisfactory conservative management in the acute situation.


1993 ◽  
Vol 27 (2) ◽  
pp. 167-170 ◽  
Author(s):  
Karen A. Pallone ◽  
Morton P. Goldman ◽  
Matthew A. Fuller

Objective To describe a case of isoniazid-associated psychosis and review the incidence of this adverse effect. Data Sources Information about the patient was obtained from the medical chart. A MEDLINE search of the English-language literature published from 1950 to 1992 was conducted and Index Medicus was manually searched for current information. Study Selection All case reports describing isoniazid-associated psychosis were reviewed. Data Extraction Studies were evaluated for the use of isoniazid, symptoms of psychosis, onset of symptoms, and dosage of isoniazid. Data Synthesis The case report is compared with others reported in the literature. The incidence of isoniazid-associated psychosis is rare. Conclusions The mechanism of isoniazid-associated psychosis is uncertain. It appears that isoniazid was associated with the psychosis evident in our patient and in the cases reviewed.


2012 ◽  
Vol 33 (6) ◽  
pp. E10 ◽  
Author(s):  
Jonathan A. Forbes ◽  
Ahmed J. Awad ◽  
Scott Zuckerman ◽  
Kevin Carr ◽  
Joseph S. Cheng

Object The authors' goal was to better define the relationship between biomechanical parameters of a helmeted collision and the likelihood of concussion. Methods The English-language literature was reviewed in search of scholarly articles describing the rotational and translational accelerations observed during all monitored impact conditions that resulted in concussion at all levels of American football. Results High school players who suffer concussion experience an average of 93.9g of translational acceleration (TA) and 6505.2 rad/s2 of rotational acceleration (RA). College athletes experience an average of 118.4g of TA and 5311.6 rad/s2 of RA. While approximately 3% of collisions are associated with TAs greater than the mean TA associated with concussion, only about 0.02% of collisions actually result in a concussion. Associated variables that determine whether a player who experiences a severe collision also experiences a concussion remain hypothetical at present. Conclusions The ability to reliably predict the incidence of concussion based purely on biomechanical data remains elusive. This study provides novel, important information that helps to quantify the relative insignificance of biomechanical parameters in prediction of concussion risk. Further research will be necessary to better define other factors that predispose to concussion.


2019 ◽  
Vol 11 (1) ◽  
pp. 36-46 ◽  
Author(s):  
Przemysław Dębski ◽  
Ewelina Białas ◽  
Rafał Gnat

AbstractSelf-myofascial release (SMR) is a well-known and popular therapy. Its growing popularity is based on high effectiveness and availability. However, there is a lack of agreement about which parameters should be used to optimize the effects of the therapy. The purpose of this review is to critically select and assess current literature and ascertain the values of the follow­ing parameters: (1) therapy duration, (2) volume of applied pressure, (3) speed and (4) frequency of roll, (5) type of roller, (6) the number of treatment applications during one session, (7) the duration of intervals between applications that yield the best results in terms of soft tissue.The authors launched their research in May 2018. The search strategy included the electronic databases EBSCOhost and PubMed. The following inclusion criteria were assessed:- English language, high quality manuscripts (evaluation in PEDro scale)- at least one of the groups using the foam roller, tennis ball or the stick to fascial release- basic parameters of therapy described.A total 55 articles met the inclusion criteria. Patients can usually withstand a maximum tolerable pressure for 30-120 seconds, repeated 1-3 times, separated by 30 seconds of rest. The intensity of a single rolling movement should be moderate, and the movement should last about 3 seconds. Keeping the roller on particularly sensitive areas is recommended to release tension and enhance blood perfusion.Currently, there is no consensus on an optimal FR programme. However, there is a tendency to use SMR tools with a physiol­ogy-based method to enhance therapeutic efficiency.


2003 ◽  
Vol 112 (3) ◽  
pp. 287-292 ◽  
Author(s):  
Giuseppe Magliulo ◽  
Erika Parnasi ◽  
Raffaello D'Amico ◽  
Vincenzo Savastano ◽  
Salvatore Romeo

Facial paraganglioma is an extremely rare tumor that originates from abnormal paraganglionic tissue situated in the intrapetrous facial canal. A review of the English-language literature shows that only 8 cases of facial nerve paraganglioma have been published. In each case the facial glomus presented itself sporadically, completely independent of any other form of paraganglioma. This study reports an intrapetrous facial glomus that occurred in a case of multiple paragangliomas with a hereditary pattern. To our knowledge, this is the first report of such a combination.


Author(s):  
Ordean A ◽  
◽  
Pollieri E ◽  
Giby K ◽  
◽  
...  

Introduction: Non-medical cannabis use and anxiety disorders are highly prevalent among Canadian women; however, the direction of this assocation remains controversial. The objective of this article is to provide an evidencebased update regarding the effect of non-medical cannabis on anxiety symptoms in women. Methods: A literature search was conducted using PsychINFO and MEDLINE for articles related to cannabis and marijuana use among women with anxiety or anxiety disorders. Only English language literature from 2010 to 2020 was reviewed. Studies including patients under the age of 18 and studies addressing medical cannabis were excluded. Four studies met our inclusion criteria for this review. Results: Cannabis use and anxiety disorders are both highly prevalent among young women. Other substance use in addition to cannabis is frequently reported by women. Reasons for cannabis use by women with anxiety differed from those of men. Findings did not show a direct association between cannabis use and anxiety symptoms. Women who used cannabis did not report higher rates of anxiety nor did anxiety predict the onset of cannabis use. Conclusion: There is no evidence to indicate that non-medical cannabis use worsens anxiety symptoms among women. Further studies should focus on reducing potential confounding factors and developing a reliable method of quantifying cannabis use in order to determine the direction of the interaction between cannabis and anxiety disorders among women.


2013 ◽  
Vol 15 (3) ◽  
pp. 113-118 ◽  
Author(s):  
Ruth Ann Marrie ◽  
Caroline Gryba

Interest in neuromyelitis optica (NMO) has increased substantially over the last few years, but it is not known whether NMO has the same geographic and temporal variations in disease risk as multiple sclerosis (MS). We aimed to evaluate the worldwide incidence and prevalence of NMO through a systematic review of published peer-reviewed studies. We performed a search of the English-language literature using MEDLINE and EMBASE from January 1985 to March 2012. Search terms included “neuromyelitis optica,” “Devic's,” “opticospinal,” “incidence,” “prevalence,” and “epidemiology.” We assessed study quality using a standardized instrument. A total of five studies met the inclusion criteria. Three of the studies were from North America, and all studies were published between 2005 and 2012. All studies were of good quality, but only one study reported standardized rates, and subgroup-specific estimates were rarely reported. The incidence of NMO per 100,000 population ranged from 0.053 to 0.40, while the prevalence per 100,000 population ranged from 0.52 to 4.4. Heterogeneity was high among the incidence (I2 = 68.0%) and prevalence studies (I2 = 94.0%). This review highlights the limited knowledge regarding the epidemiology of NMO and the importance of obtaining estimates standardized to common populations to enhance comparability of studies from different jurisdictions. Future studies would also benefit from reporting age-, sex-, and race- or ethnicity-specific estimates.


2003 ◽  
Vol 6 (2) ◽  
pp. 137-141 ◽  
Author(s):  
Fabiola S. Balarezo ◽  
Richard C. Muller ◽  
Richard G. Weiss ◽  
Timothy Brown ◽  
David Knibbs ◽  
...  

Perineuromas (PN) are uncommon, slowly growing, usually benign tumors composed of well-differentiated perineural cells. Two variants are recognized: intraneural perineuromas and soft tissue perineuroma, which includes a sclerosing subset of tumors. They are usually reported in the adult population. We present three cases of soft tissue perineuromas in children. One was located in the deep soft tissue of the retroperitoneum in a 14-year-old girl, the second one in the left thumb of a 14-year-old boy, and the third one in the index finger of a 16-year-old boy. This report, which describes the clinicopathologic, immunohistochemical, and ultrastructural features of these tumors, should alert pathologists to the occurrence of perineuromas in children. A review of the English language literature on perineuromas in children is also included.


Neurosurgery ◽  
2011 ◽  
Vol 69 (3) ◽  
pp. 630-643 ◽  
Author(s):  
Robert E Elliott ◽  
John A Jane ◽  
Jeffrey H Wisoff

Abstract BACKGROUND: Controversy persists regarding the optimal treatment of pediatric craniopharyngiomas. OBJECTIVE: We performed a meta-analysis of reported series of transcranial (TC) and transsphenoidal (TS) surgery for pediatric craniopharyngiomas to determine whether comparisons between the outcomes in TS and TC approaches are valid. METHODS: Online databases were searched for English-language articles reporting quantifiable outcome data published between 1990 and 2010 pertaining to the surgical treatment of pediatric craniopharyngiomas. Forty-eight studies describing 2955 patients having TC surgery and 13 studies describing 373 patients having TS surgery met inclusion criteria. RESULTS: Before surgery, patients who had TC surgery had less visual loss, more frequent hydrocephalus and increased intracranial pressure, larger tumors, and more suprasellar disease. After surgery, patients in the TC group had lower rates of gross total resection (GTR), more frequent recurrence after GTR, higher neurological morbidity, more frequent diabetes insipidus, less improvement, and greater deterioration in vision. There was no difference in operative mortality, obesity/hyperphagia, or overall survival percentages. CONCLUSION: Directly comparing outcomes after TC and TS surgery for pediatric craniopharyngiomas does not appear to be valid. Baseline differences in patients who underwent each approach create selection bias that may explain the improved rates of disease control and lower morbidity of TS resection. Although TS approaches are becoming increasingly used for smaller tumors and those primarily intrasellar, tumors more amenable to TC surgery include large tumors with significant lateral extension, those that engulf vascular structures, and those with significant peripheral calcification.


2021 ◽  
pp. 173-183
Author(s):  
Pamela Denisse Soberanis-Piña ◽  
Ricardo Fernández-Ferreira ◽  
Héctor Hugo Buerba-Vieregge ◽  
Edgar Varela-Santoyo ◽  
Jerónimo Rafael Rodriguez-Cid ◽  
...  

Myoepithelial carcinoma, also known as malignant myoepithelioma, is considered an extremely rare (0.45–1%) malignant salivary gland neoplasm. Approximately 100 cases have been reported in the English-language literature on myoepithelial carcinoma. The majority of the myoepitheliomas described in the literature have been benign, and the malignant counterpart is considered rare (<1%). Such a tumor may appear de novo or rarely develop from a preexisting pleomorphic adenoma (<20%), and in exceedingly rare cases (<0.5%), it has arisen from a benign myoepithelioma (i.e., plasmacytoid myoepithelioma). To our knowledge, no case of myoepithelial carcinoma of the parotid gland arising in a plasmacytoid myoepithelioma synchronized with melanoma has been reported to date. The treatment of myoepithelial carcinoma has been mainly surgical, including wide excision with free margins, with or without nodal dissection. The roles of chemotherapy and radiotherapy have not yet been established. We report a case of myoepithelial carcinoma of the parotid gland arising in a plasmacytoid myoepithelioma synchronized with melanoma in a 40-year-old woman. In our case, a complete response was achieved with surgery followed by adjuvant chemotherapy based on carboplatin and paclitaxel concurrent with radiotherapy.


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