scholarly journals The Incidence and Prevalence of Neuromyelitis Optica

2013 ◽  
Vol 15 (3) ◽  
pp. 113-118 ◽  
Author(s):  
Ruth Ann Marrie ◽  
Caroline Gryba
Keyword(s):  
Neuromyelitis Optica ◽  
English Language ◽  
Disease Risk ◽  
Temporal Variations ◽  
Study Quality ◽  
Inclusion Criteria ◽  
Future Studies ◽  
Prevalence Studies ◽  
Search Terms ◽  
Language Literature

Interest in neuromyelitis optica (NMO) has increased substantially over the last few years, but it is not known whether NMO has the same geographic and temporal variations in disease risk as multiple sclerosis (MS). We aimed to evaluate the worldwide incidence and prevalence of NMO through a systematic review of published peer-reviewed studies. We performed a search of the English-language literature using MEDLINE and EMBASE from January 1985 to March 2012. Search terms included “neuromyelitis optica,” “Devic's,” “opticospinal,” “incidence,” “prevalence,” and “epidemiology.” We assessed study quality using a standardized instrument. A total of five studies met the inclusion criteria. Three of the studies were from North America, and all studies were published between 2005 and 2012. All studies were of good quality, but only one study reported standardized rates, and subgroup-specific estimates were rarely reported. The incidence of NMO per 100,000 population ranged from 0.053 to 0.40, while the prevalence per 100,000 population ranged from 0.52 to 4.4. Heterogeneity was high among the incidence (I2 = 68.0%) and prevalence studies (I2 = 94.0%). This review highlights the limited knowledge regarding the epidemiology of NMO and the importance of obtaining estimates standardized to common populations to enhance comparability of studies from different jurisdictions. Future studies would also benefit from reporting age-, sex-, and race- or ethnicity-specific estimates.

scholarly journals Amputee football in practice and research

2016 ◽  
Vol 30 (4) ◽  
pp. 55-66 ◽  
Author(s):  
Zofia Kasińska ◽  
Tomasz Tasiemski
Keyword(s):  
English Language ◽  
Scientific Paper ◽  
Football Players ◽  
Inclusion Criteria ◽  
Future Studies ◽  
Long Time ◽  
History Of ◽  
The Subject ◽  
Academic Search ◽  
Rules Of The Game

Abstract Introduction: Sport for people with disabilities has interested scientists for a long time. However, there is a scarcity of research on the subject of amputee football – football adapted to individuals after amputations. The aim of the study was to describe this sport and to review research carried out in this field so far. When looking for investigations on amputee football, the available computer databases (Academic Search Complete, SPORTdiscus, MEDLINE, Health Source, Master-FILE Premier) were searched comprehensively. The following key words were used to identify proper articles: amputee football, football + amputations, crutch football. Also, the following article inclusion criteria were applied: (A) original scientific paper, (B) available full text of paper, (C) paper published in a peer-reviewed journal, (D) paper published in the English language. Eleven articles that met the criteria were selected for the analysis. Description of amputee football: The description of amputee football included the history of the sport in the world and in Poland, rules of the game and players’ classification. Amputee football in research: The articles selected for the review were divided into three categories: 1) psychological and social aspects, 2) anthropomotorics and nutrition, 3) endurance, physical capacity and speed abilities. . Summary: The majority of studies carried out so far have focused on general characteristics of amputee football players and the effects of this sport on the functioning of individuals after amputations. Future studies ought to involve injury-related aspects as well as training effectiveness on the basis of physiological parameters.

The Fundamentals of Resident Dismissal

2017 ◽  
Vol 83 (2) ◽  
pp. 119-126 ◽  
Author(s):  
Paul J. Schenarts ◽  
Sean Langenfeld
Keyword(s):  
English Language ◽  
Clinical Performance ◽  
Legal Aspects ◽  
Program Director ◽  
Resident Evaluation ◽  
Breach Of Contract ◽  
Educational Malpractice ◽  
Search Terms ◽  
Language Literature ◽  
Legal Opinion

Residents have the rights and responsibilities of both students and employees. Dismissal of a resident from a training program is traumatic and has lasting repercussions for the program director, the faculty, the dismissed resident, and the residency. A review of English language literature was performed using PUBMED and OVID databases, using the search terms, resident dismissal, resident termination, student dismissal, student and resident evaluation, legal aspects of education, and remediation. The references of each publication were also reviewed to identify additional appropriate citations. If the Just Cause threshold has been met, educators have the absolute discretion to evaluate academic and clinical performance. Legal opinion has stated that it is not necessary to wait until a patient is harmed to dismiss a resident. Evaluations should be standard and robust. Negative evaluations are not defamatory as the resident gave consent to be evaluated. Provided departmental and institutional polices have been followed, a resident can be dismissed without a formal hearing. Residencies are entitled to modify academic requirements and dismissal is not considered a breach of contract. Although there is anxiety regarding resident dismissal, the courts have uniformly supported faculty having this role. When indicated, failure to dismiss a resident also places the program director and the faculty at risk for educational malpractice.

050 Latitude continues to be associated with ms prevalence: an updated meta-analysis

2018 ◽  
Vol 89 (6) ◽  
pp. A21.1-A21
Author(s):  
Wendy Wang ◽  
Steve Simpson ◽  
Bruce Taylor
Keyword(s):  
Latitudinal Gradient ◽  
Meta Analysis ◽  
Sun Exposure ◽  
European Population ◽  
Inclusion Criteria ◽  
Specific Data ◽  
Prevalence Studies ◽  
Search Terms ◽  
Prevalence Estimates ◽  
Genetic And Environmental Factors

IntroductionPrevious studies have demonstrated a strong latitudinal gradient in multiple sclerosis (MS) prevalence, likely related to interplay between genetic and environmental factors, particularly vitamin D and sun exposure. Herein, we update our 2010 meta-analysis of the latitudinal gradient of MS prevalence, seeking to assess the presence and magnitude of the gradient and whether it has changed since our 2010 analysis.MethodsStudies published between 2010 and 2017 were located via EMBASE, ISI and PubMed, using standardised search terms; data was extracted from peer-reviewed studies. These studies were added to the studies collected in our previous analysis. Prevalence estimates were adjusted for study prevalence year. Where age/sex-specific data were available, prevalence values were age/sex standardised to the 2009 European population. For the 2010–2017 interval, 85 prevalence studies were found, 53 of which met inclusion criteria, yielding 108 new prevalence points. The latitudinal association with MS prevalence was assessed by meta-regression.ResultsThere was a significant positive gradient in MS prevalence with increasing latitude (6.89/100,000 per degree latitude), attenuating slightly to 5.60/100,000 on age-standardisation, these associations persisting on adjustment for diagnostic criteria used. Of note, the age-standardised gradient was significantly stronger (p=0.044) than that from our previous study.ConclusionThis updated meta-analysis confirms that MS prevalence is still strongly positively associated with increasing latitude.

Non-audiofacial morbidity after Gamma Knife surgery for vestibular schwannoma

2009 ◽  
Vol 27 (6) ◽  
pp. E4 ◽  
Author(s):  
Michael E. Sughrue ◽  
Isaac Yang ◽  
Seunggu J. Han ◽  
Derick Aranda ◽  
Ari J. Kane ◽  
...  
Keyword(s):  
Vestibular Schwannoma ◽  
English Language ◽  
Outcome Data ◽  
Vestibular Schwannomas ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
Dose Cohort ◽  
Shunt Treatment ◽  
Comprehensive Search ◽  
Language Literature

Object While many studies have been published outlining morbidity following radiosurgical treatment of vestibular schwannomas, significant interpractitioner and institutional variability still exists. For this reason, the authors conducted a systematic review of the literature for non-audiofacial-related morbidity after the treatment of vestibular schwannoma with radiosurgery. Methods The authors performed a comprehensive search of the English-language literature to identify studies that published outcome data of patients undergoing radiosurgery treatment for vestibular schwannomas. In total, 254 articles were found that described more than 50,000 patients and were analyzed for satisfying the authors' inclusion criteria. Patients from these studies were then separated into 2 cohorts based on the marginal dose of radiation: ≤ 13 Gy and > 13 Gy. All tumors included in this study were < 25 mm in their largest diameter. Results A total of 63 articles met the criteria of the established search protocol, which combined for a total of 5631 patients. Patients receiving > 13 Gy were significantly more likely to develop trigeminal nerve neuropathy than those receiving < 13 Gy (p < 0.001). While we found no relationship between radiation dose and the rate of developing hydrocephalus (0.6% for both cohorts), patients with hydrocephalus who received doses > 13 Gy appeared to have a higher rate of symptomatic hydrocephalus requiring shunt treatment (96% [> 13 Gy] vs 56% [≤ 13 Gy], p < 0.001). The rates of vertigo or balance disturbance (1.1% [> 13 Gy] vs 1.8% [≤ 13 Gy], p = 0.001) and tinnitus (0.1% [> 13 Gy] vs 0.7% [≤ 13 Gy], p = 0.001) were significantly higher in the lower dose cohort than those in the higher dose cohort. Conclusions The results of our review of the literature provide a systematic summary of the published rates of nonaudiofacial morbidity following radiosurgery for vestibular schwannoma.

Association between Non-Medical Cannabis Use and Anxiety Disorders in Women

2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Ordean A ◽  
◽  
Pollieri E ◽  
Giby K ◽  
◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Young Women ◽  
English Language ◽  
Anxiety Symptoms ◽  
Cannabis Use ◽  
Inclusion Criteria ◽  
Medical Cannabis ◽  
Direct Association ◽  
Language Literature ◽  
Reducing Potential

Introduction: Non-medical cannabis use and anxiety disorders are highly prevalent among Canadian women; however, the direction of this assocation remains controversial. The objective of this article is to provide an evidencebased update regarding the effect of non-medical cannabis on anxiety symptoms in women. Methods: A literature search was conducted using PsychINFO and MEDLINE for articles related to cannabis and marijuana use among women with anxiety or anxiety disorders. Only English language literature from 2010 to 2020 was reviewed. Studies including patients under the age of 18 and studies addressing medical cannabis were excluded. Four studies met our inclusion criteria for this review. Results: Cannabis use and anxiety disorders are both highly prevalent among young women. Other substance use in addition to cannabis is frequently reported by women. Reasons for cannabis use by women with anxiety differed from those of men. Findings did not show a direct association between cannabis use and anxiety symptoms. Women who used cannabis did not report higher rates of anxiety nor did anxiety predict the onset of cannabis use. Conclusion: There is no evidence to indicate that non-medical cannabis use worsens anxiety symptoms among women. Further studies should focus on reducing potential confounding factors and developing a reliable method of quantifying cannabis use in order to determine the direction of the interaction between cannabis and anxiety disorders among women.

A Systematic Review of Pica and Geophagy in Japan and Korea

2019 ◽  
Vol 2 (4) ◽  
pp. 69-76
Author(s):  
Christopher D. Golden ◽  
Curie Ahn ◽  
Yusuke Okubo ◽  
Satowa Suzuki ◽  
Young S. Yi
Keyword(s):  
Public Health ◽  
English Language ◽  
Medical Evidence ◽  
Culturally Specific ◽  
Factors Associated ◽  
Search Terms ◽  
The World ◽  
Broad Variety ◽  
Specific Factors ◽  
Language Literature

Pica, the craved and purposive consumption of non-food substances, is a globally widespread behavior that has critical connections to public health. Although there is a rich literature describing these behaviors from nearly every culture around the world, there is a dearth of English language literature reporting these behaviors in Japan and Korea. Here, we systematically reviewed the medical evidence of pica in Korean and Japanese language journals to confirm their presence in these cultures and to characterize culturally-specific factors associated with these behaviors. We used Ichusi-Web and KoreaMed with a broad variety of recombined search terms including “pica,” “geophagy,” “amylophagy,” and “trichobezoar” in Korean and Japanese characters. Our results confirm that pica is present in both of these cultures, with particularly frequent reports of trichobezoar (the consumption of human hair).

scholarly journals Yoga as an Alternative and Complimentary Therapy for Cardiovascular Disease

2016 ◽  
Vol 22 (2) ◽  
pp. 310-316 ◽  
Author(s):  
Taj Haider ◽  
Manoj Sharma ◽  
Paul Branscum
Keyword(s):  
Cardiovascular Disease ◽  
English Language ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Small Sample ◽  
Inclusion Criteria ◽  
Attrition Rates ◽  
Breathing Techniques ◽  
Patients At Risk ◽  
Small Sample Sizes

Cardiovascular disease is a leading cause of disability and death worldwide. Yoga, a mind-body exercise, utilizes breathing techniques with low-impact physical activity that may be an alternative treatment for cardiovascular disease. The purpose of this systematic review was to examine yoga interventions for patients at-risk for and/or suffering from cardiovascular disease. The inclusion criteria for interventions were ( a) published in the English language between 2005 and 2015; ( b) indexed in MEDLINE/PubMed, CINAHL, or Alt HealthWatch; ( c) employed a quantitative design; and ( d) applied a yoga intervention. Twelve interventions met the inclusion criteria, of which, all documented significant improvements in one or more factors associated with cardiovascular disease. Limitations to the studies in this review included a lack of studies adhering to the inclusion criteria, small sample sizes, and high attrition rates. Despite the limitations, this review demonstrates the clear potential yoga has as an alternative and complementary means to improve cardiovascular disease risk.

The Potential Clinical Implications and Importance of Drug Interactions Between Anticancer Agents and Cannabidiol in Patients With Cancer

2019 ◽  
Vol 33 (4) ◽  
pp. 506-512 ◽  
Author(s):  
Brandon J. Opitz ◽  
Marissa L. Ostroff ◽  
Arin C. Whitman
Keyword(s):  
Anticancer Agents ◽  
English Language ◽  
Clinical Implications ◽  
Inclusion Criteria ◽  
Patients With Cancer ◽  
Pharmacodynamic Interactions ◽  
Search Terms ◽  
Minimal Data

The objective of this review was to identify and examine the pharmacokinetic and pharmacodynamic interactions between cannabidiol (CBD)-only products, such as CBD oil, and anticancer agents. A literature search of PubMed (1980 to September 2018) and the Cochrane Collection (1980 to September 2018) was performed using the following search terms: “cannabidiol,” “cancer,” “cannabis,” “marijuana,” and “interaction,” as well as any combination of these terms. Literature was excluded if it did not appear in the search when limited to the “full text” filter on PubMed, if it was not published in the English language, or if it did not explore potential pharmacodynamic or pharmacokinetic interactions of CBD and anticancer agents. There were 10 studies that met these inclusion criteria. The majority of the facts regarding the interactions with CBD were found using in vitro studies and the true in vivo implications are not well-known. Minimal data were available regarding the interactions between CBD and anticancer agents. However, pharmacists should always consider the possibility of interactions and their consequences whenever they are aware of a patient using CBD products.

scholarly journals Measuring Awareness in People With Dementia: Results of a Systematic Scoping Review

2020 ◽  
pp. 089198872092471
Author(s):  
Catherine M. Alexander ◽  
Anthony Martyr ◽  
Sharon A. Savage ◽  
Robin G. Morris ◽  
Linda Clare
Keyword(s):  
Scoping Review ◽  
Clinical Utility ◽  
English Language ◽  
Well Being ◽  
Personal Health ◽  
Inclusion Criteria ◽  
Search Terms ◽  
People With Dementia ◽  
Moderate Dementia ◽  
Pick Disease

Background: Awareness of the diagnosis or related changes in functioning varies in people with dementia (PwD), with implications for the well-being of PwD and their carers. Measuring awareness in a clinical setting could facilitate tailored support and optimize involvement in personal health and care decisions. This scoping review aimed to identify validated methods of assessing awareness in dementia and appraise their clinical utility. Method: A systematic search was conducted of English-language publications that measured awareness in PwD, in 6 electronic databases. Search terms included dement*, Alzheimer*, Pick disease, and awareness, unawareness, anosognosia, insight, denial, metacognit*, or discrepanc*. Results: We screened 30,634 articles, finding 345 articles that met our inclusion criteria. We identified 76 measures, most commonly using a discrepancy questionnaire comparing evaluations of function by PwD and an informant. There were 30 awareness measures developed and validated for use in dementia populations but few designed for general clinical use. Conclusions: Although we found a range of clinical indications for measuring awareness, there were few studies investigating clinical applications and few tools designed for clinical purposes. Further investigation and development of a person-centered tool could facilitate health and care choices in mild-to-moderate dementia.

Pharmacologic Treatment of Opioid-Induced Sedation in Chronic Pain

2005 ◽  
Vol 39 (4) ◽  
pp. 727-731 ◽  
Author(s):  
James E Reissig ◽  
Amy M Rybarczyk
Keyword(s):  
Chronic Pain ◽  
Trial Design ◽  
English Language ◽  
Data Sources ◽  
Pharmacologic Treatment ◽  
Data Synthesis ◽  
Search Terms ◽  
Limited Support ◽  
Pharmacologic Management ◽  
Language Literature

OBJECTIVE: To review the literature for pharmacologic management of opioid-induced sedation (OIS) in patients with chronic pain. DATA SOURCES: A search of MEDLINE (1966–October 2004) for English-language literature and selected bibliographies was completed. Search terms included pain, opioid, sedation, psychostimulants, amphetamines, modafinil, and donepezil. DATA SYNTHESIS: Amphetamines and amphetamine-like agents, caffeine, donepezil, and modafinil have been evaluated for OIS. Available literature is limited by numbers of subjects, duration, and trial design; however, there is limited support for the use of methylphenidate, donepezil, and modafinil. CONCLUSIONS: Pharmacologic treatment of OIS should be utilized selectively, given the available literature. Methylphenidate, donepezil, and modafinil may be considered in appropriate patients.

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