scholarly journals Panoramic Radiographic Assessment of Agenesis of Mandibular Third Molars: A Hospital Based Study in Eastern Nepal

2019 ◽  
Vol 57 (217) ◽  
Author(s):  
Pragya Regmee ◽  
Jyotsna Rimal ◽  
Ichha Kumar Maharjan ◽  
Surya Raj Niraula
Keyword(s):  
Panoramic Radiograph ◽  
The Other ◽  
Third Molars ◽  
Radiographic Assessment ◽  
Review Committee ◽  
Oral Medicine ◽  
Chi Square ◽  
Institutional Review ◽  
Chi Square Test ◽  
Mandibular Third Molars

Introduction: Racial variation, genetic inheritance and various other factors can affect the jaw size and ultimately the tooth size and number. Studies for agenesis of mandibular third molars (M3s) have been carried out in various populations but data relating to these are not evident from most of the parts of Nepal. Hence, the objective of the present study is to determine the prevalence of agenesis among the population of patients visiting the Department of Oral Medicine and Radiology of this institute. The study also sought the odds of agenesis of M3 in one side when there was missing M3 on the other side of the mandible. Methods: This study was conducted after the approval from Institutional Review Committee of BPKIHS. Two hundred and eighty four patients (568 sites of M3, bilaterally), visiting the Department of Oral Medicine and Radiology were studied with Panoramic Radiograph to assess for agenesis of mandibular third molars, bilaterally. Percentage of agenesis was calculated and chi square test was applied where relevant. Odds ratio was also calculated. Results: Agenesis was seen in 28.7% of the participants. The Odds of M3 being missing on one side with concurrent missing M3 on the other side was 40.27 (Confidence Interval 19.34 to 83.87). Conclusions: Agenesis was highly prevalent in this study group. The likelihood of M3 being absent on one side, when there was concurrent missing M3 on the other side of mandible was also high.

scholarly journals The prediction of impacted versus spontaneously erupted mandibular third molars

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Amanda Silva De Sousa ◽  
José Valladares - Neto ◽  
David Normando
Keyword(s):  
Kappa Statistics ◽  
X Rays ◽  
Third Molars ◽  
Accuracy Rate ◽  
Predictive Capacity ◽  
Chi Square ◽  
X Ray ◽  
Prognostic Accuracy ◽  
Chi Square Test ◽  
Mandibular Third Molars

Abstract Background To evaluate the predictive capacity of orthodontists and oral maxillofacial surgeons (OMFSs) in anticipating the process of impaction or eruption of lower third molars (L3Ms) through the examination of serial panoramic radiographs. Methods Sixty-eight lower third molars (L3Ms) were analyzed in 34 orthodontically treated patients without extraction. Twenty-seven OMFSs and 27 orthodontists were randomized in order to analyze the radiographs. Initially, the evaluators issued the prognosis for the L3Ms in XR1, a posterior for the XR1 + XR2. Concordance of the diagnosis was examined using Kappa statistics, and the differences between the groups of evaluators were examined using the chi-square test at p<0.05. Results When examining XR1 in cases where the teeth erupted spontaneously, the prognostic accuracy rate for OMFSs and orthodontists was similar, 63 and 65.7%, respectively (p=0.19). When evaluating XR1 + XR2, the accuracy among orthodontists (60%) was similar to that reported for XR1 (p=0.19), while OMFSs presented a reduction in the accuracy (55.3%, p<0.0001). When the L3Ms remained impacted, accuracy in XR1 was lower than in spontaneously erupting L3Ms, although similar between OMFSs (50.1%) and orthodontists (49.1%). Furthermore, for impacted L3Ms, when examining XR1 + XR2, the OMFSs presented a significant higher accuracy (71.8%, p <0.0001). Conclusions Orthodontists and OMFSs seem unable to predict spontaneous eruption or impaction of the lower third molars from single or longitudinal x-rays. When adding a second longitudinal x-ray, orthodontists and more significantly OMFSs tend to indicate more extractions.

scholarly journals Mandibular Third Molars and Lower Anterior Crowding: Comparison of Opinions of Oral-Maxillofacial Surgeons and Orthodontists

2019 ◽  
Vol 7 (4) ◽  
pp. 265-264
Author(s):  
Muhammad Azeem ◽  
Muhammad Mudassar Saleem ◽  
Sana Mehmood Qureshi ◽  
Arshad Mehmood ◽  
Muhammad Imran Khan ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Third Molar ◽  
Descriptive Study ◽  
Third Molars ◽  
Online Questionnaire ◽  
Chi Square ◽  
Anterior Crowding ◽  
Chi Square Test ◽  
Mandibular Third Molars

Objective: To compare the opinion of orthodontists and oral-maxillofacial surgeons on relation between erupting mandibular third molars and lower incisal crowding.Patients and Methods: This descriptive study involved 100 Pakistani clinicians (50 orthodontists, 50 oral-maxillofacial surgeons) to answer online questionnaire regarding their opinions on link between erupting Mandibular Third Molars along with their extraction opinion with reference to development and prevention of lower incisal crowding. Data was analyzed using SPSS version 21.0. Pearson's chi-square test was applied and statistical significance was defined at <=0.05.Results: Statistically insignificant differences were found between oral-maxillofacial surgeons and orthodontists regarding question of erupting mandibular third molars in causing lower incisal crowding. Similarly, statistically insignificant differences between oral-maxillofacial surgeons and orthodontists were found regarding question of recommending preventive extraction of mandibular third molars for developing lower incisal crowding.Conclusion: No opinion differences were observed between Pakistani oral surgeons and orthodontists, regarding the link of lower third molar as a cause of lower incisal crowding.

Comparison of Clinical Outcomes With Drug Coated Balloons Versus Plain Balloon Angioplasty In Chronic Limb-Threatening Ischemia

2021 ◽  
pp. 153857442110225
Author(s):  
Joel Mathew John ◽  
Vimalin Samuel ◽  
Dheepak Selvaraj ◽  
Prabhu Premkumar ◽  
Albert A Kota ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Interventional Procedure ◽  
Tertiary Care ◽  
Arterial Disease ◽  
Multivariable Logistic Regression Analysis ◽  
Tertiary Care Centre ◽  
Chi Square ◽  
Exact Test ◽  
Institutional Review ◽  
Chi Square Test

Objective: The use of drug coated balloon (DCB) for angioplasty has shown superior efficacy against plain balloons for treating complex infrainguinal arterial disease. We report and compare the clinical outcomes following application of DCB(Paclitaxel) and plain angioplasty (POBA) in our tertiary care centre. Methods: A retrospective, single centre analysis of 301 patients with chronic limb-threatening ischemia involving the infrainguinal segment was conducted between September 2014 and September 2018, after approval from the Institutional review board. We analyzed clinical outcomes by measuring postoperative ABI improvement, restenosis requiring reintervention procedure, minor and major amputations at the end of 18 months. . To find the association between the group variables (POBA and DCB) and other risk variables, Chi-square test/Fisher’s exact test was used. Multivariable logistic regression analysis was used. Results: Patients who underwent treatment with plain balloon (POBA) and DCB(Paclitaxel) angioplasty were 246(81.7%) and 55(18.3%) respectively. Our study group was predominantly male (Male: Female = 6.7:1), most patients were more than 50 years of age (n = 251, 83.4%). Smoking (n = 199, 66.1%) and diabetes (n = 210, 69.8%) were the most common atherosclerotic risk factors. Postoperative Ankle Brachial Pressure Index (ABI) improvement were similar in both groups (POBA = 57.7%; DCB = 69.8%; p = 0.103). Minor and major amputations following POBA were 26% and 22%; and DCB were 12.7% and 16.4% respectively. Re-stenosis requiring a re-interventional procedure within 18 months was 15%, (n = 37) following POBA; and 12.7% (n = 7) following DCB (p = 0.661). Conclusions: This retrospective study shows similar clinical limb related outcomes following POBA and DCB at 18 months. However, our comparative analysis between the POBA and DCB groups was totally unadjusted and not adjusted for common confounders such as age and sex. Hence, for one to draw definitive conclusions leading to changes in clinical practice; a randomized, prospective study with a larger patient cohort is needed.

scholarly journals An audit of US FDA warning letters issued to sponsors, institutional review boards and investigators over a six-year period

2021 ◽  
pp. 01-06
Author(s):  
Unnati Saxena ◽  
Debdipta Bose ◽  
Shruti Saha ◽  
Nithya J Gogtay ◽  
Urmila M Thatte
Keyword(s):  
Adverse Drug Events ◽  
The United States ◽  
Institutional Review Boards ◽  
Chi Square ◽  
Institutional Review ◽  
United States Food ◽  
Post Marketing ◽  
Chi Square Test ◽  
Us Fda ◽  
Review Boards

The present audit was carried out with the objective of evaluating warning letters (WLs) issued to trial sponsors, clinical investigators and institutional review boards (IRBs) by the United States Food and Drug Administration during a six-year period and compare it with two similar earlier audits. WLs were reviewed and classified as per stakeholders and further categorised as per predefined violation themes. The chi-square test was performed for trend analysis of WLs. A total of 62 WLs were issued to the three stakeholders. The maximum number of WLs were issued to the clinical investigators (36/62, 58.06%), followed by sponsors (19/62, 30.64%), and least to the IRBs (7/62, 11.29%). Among sponsors, lack of standard operating procedures for the monitoring, receipt, evaluation and reporting of post-marketing adverse drug events was the most common violation theme (8/19, 42.1%). Among clinical investigators, deviation from investigational plan was the most common violation theme (31/36, 86.11%.). For IRBs, inadequate documentation was the most common violation theme (6/7, 85.71%). We saw an overall reduction in the number of WLs issued to the stakeholders. Thus, we identified multiple areas on which each stakeholder should work for improvement.

scholarly journals Performance verification of anti-SARS-CoV-2-specific antibody detection by using four chemiluminescence immunoassay systems

2020 ◽  
Vol 57 (6) ◽  
pp. 429-434
Author(s):  
Yafang Wan ◽  
Zhijie Li ◽  
Kun Wang ◽  
Tian Li ◽  
Pu Liao
Keyword(s):  
False Positive ◽  
Detection System ◽  
False Positive Rate ◽  
Antibody Test ◽  
The Other ◽  
Antibody Detection ◽  
Igg Antibody ◽  
Chi Square ◽  
Chemiluminescence Immunoassay ◽  
Chi Square Test

Objectives The purpose of the current study was to evaluate the analytical performance of seven kits for detecting IgM/IgG antibodies against coronavirus (SARS-CoV-2) by using four chemiluminescence immunoassay systems. Methods Fifty patients diagnosed with SARS-CoV-2 infection and 130 controls without coronavirus infection from the General Hospital of Chongqing were enrolled in the current retrospective study. Four chemiluminescence immunoassay systems, including seven IgM/IgG antibody detection kits for SARS-CoV-2 (A_IgM, A_IgG, B_IgM, B_IgG, C_IgM, C_IgG and D_Ab), were employed to detect antibody concentrations. The chi-square test, the receiver operating characteristic (ROC) curve and Youden’s index were determined to verify the cut-off value of each detection system. Results The repeatability verification results of the A, B, C and D systems are all qualified. D_Ab performed best (92% sensitivity and 99.23% specificity), and B_IgM performed worse than the other systems. Except for the A_IgM and C_IgG systems, the optimal diagnostic thresholds and cut-off values of the other kits and their recommendations are inconsistent with each other. B_IgM had the worst AUC, and C_IgG had the best diagnostic accuracy. More importantly, the B_IgG system had the highest false-positive rate for testing patients with AIDS, tumours and pregnancies. The A_IgM system test showed the highest false-positive rates among elderly individuals over 90 years old. COVID-2019 IgM/IgG antibody test systems exhibit performance differences. Conclusions The Innodx Biotech Total Antibody serum diagnosis kit is the most reliable detection system for anti-SARS-CoV-2 antibodies, which can be used together with nucleic acid tests as an alternative method for SARS-CoV-2 detecting.

scholarly journals The Chi-Square test: a frequency data based statistical device

2015 ◽  
Vol 3 (3) ◽  
pp. 53-55 ◽  
Author(s):  
Ashok Kumar
Keyword(s):  
Significant Role ◽  
Statistical Significance ◽  
The Other ◽  
Frequency Data ◽  
Chi Square ◽  
Medical Researchers ◽  
Chi Square Test ◽  
Control And Eradication

“Cause Effect” relationships are very important and play a most vital and significant role in medical researchers to reveal efficacy of medication as preventive and curative measures towards control and eradication of various diseases and morbidity factors. The present paper, in this direction is an attempt to highlight the main applicability of - test ( chi- square test ) ; a most appropriate statistical device in testing statistical significance of the above mentioned relationships in studying impact of one on the other ; supplemented by a few citations thereof.

scholarly journals Level of Satisfaction in the Use of the Wraparound Hawley and Thermoplastic Maxillary Retainers

2019 ◽  
Vol 90 (1) ◽  
pp. 63-68 ◽  
Author(s):  
Adenilson Silva Chagas ◽  
Karina Maria Salvatore Freitas ◽  
Rodrigo Hermont Cançado ◽  
Fabricio Pinelli Valarelli ◽  
Luiz Filiphe Gonçalves Canuto ◽  
...  
Keyword(s):  
The Other ◽  
Chi Square ◽  
Level Of Satisfaction ◽  
Intergroup Comparison ◽  
Significant Difference ◽  
Chi Square Test ◽  
Orthodontic Patients ◽  
Better Than

ABSTRACT Objective To compare the level of satisfaction in the use of wraparound Hawley and thermoplastic maxillary retainers. Materials and Methods The study sample included 70 orthodontic patients (24 males and 46 females), who were in the retention stage (mean age = 20.80 years). All patients wore the two types of maxillary retainer for 1 month each, along with a 3×3 fixed mandibular retainer. After the use of each retainer, the patients responded to a questionnaire evaluating the level of satisfaction with their use of the maxillary retainer. Intergroup comparison was performed by independent t tests. Chi-square test was used to evaluate preference for the type of retainer by gender. Results The thermoplastic retainer was better for swallowing and the wraparound Hawley appliance was better for hygiene and durability. The other factors evaluated (adaptation, speech, comfort, esthetics, satisfaction, and fitting) did not show significant differences between the retainers. There was also no significant difference in preference for the appliances. Conclusions Regarding the overall satisfaction and the preference, there was no difference between the wraparound Hawley and thermoplastic retainers. The wraparound Hawley appliance was better in hygiene and resistance than the thermoplastic retainer; and the thermoplastic appliance was better than the wraparound Hawley for swallowing fluids and saliva.

scholarly journals Comparing the Musculoskeletal Disorders of the Neck Between the Teachers of Physical Education and Other Majors in High Schools of Tehran City, Iran

2020 ◽  
Vol 11 (1) ◽  
pp. 43-50
Author(s):  
Elham Rahimipour Najafabadi ◽  
◽  
Reza Rajabi ◽  
Mohammad Hossein Alizade ◽  
Ali Mirabedi ◽  
...  
Keyword(s):  
High Schools ◽  
Physical Education ◽  
Musculoskeletal Disorders ◽  
Teaching Experience ◽  
The Other ◽  
Cluster Sampling ◽  
Regular Exercise ◽  
Chi Square ◽  
Chi Square Test ◽  
The Mean

Introduction: Musculoskeletal Disorders (MDs) largely contribute to occupational diseases in the workplace. Prevention from these disorders requires their evaluation in different occupations. This study aimed to compare the MDs of the neck between the teachers of Physical Education (PE) and those of the other majors in the high schools of Tehran City, Iran. Methods: The study sample included 180 teachers of mathematics, PE, and the religion and lifestyle in the high schools of Tehran (with the Mean±SD age of 42.11±6.65 years, and the Mean±SD weight of 72.28±12.98 kg). The participants were selected from 19 districts of the Tehran Departments of Education using multistage cluster sampling. The standard Nordic questionnaire was administered to investigate MDs among the teachers. The obtained data were analyzed with the Chi-square test to compare the MDs of the neck between the three groups of teachers. Results: A significant relationship was observed between the neck problems of the female (P=0.016) and male (P=0.017) PE teachers and the other teachers. Moreover, the neck problems were associated with the teaching experience (P=0.024) and teaching major (P=0.004). Conclusion: Based on the results, it seems that regular exercise can reduce the developing risk of MDs in the neck. Thus, this study recommends the performance of regular exercise and the correction of job-related postures to all teachers.

scholarly journals SPECIAL REQUIREMENTS FOR CORPORATE COMMUNICATIONS IN GEOGRAPHICALLY DEFINED MARKETS USING THE EXAMPLE OF THE SALE OF CONSTRUCTION FINANCING IN RURAL AREAS

2019 ◽  
Vol 2 (2) ◽  
pp. 185-193
Author(s):  
Christian Enz
Keyword(s):  
Rural Areas ◽  
Mortgage Lending ◽  
The Other ◽  
Corporate Communications ◽  
Chi Square ◽  
Savings Banks ◽  
Other Hand ◽  
New Business ◽  
Interest Policy ◽  
Chi Square Test

Private mortgage lending business is an important business segment for retail banks. There are two main reasons for this. Firstly, the comparatively low risk. On the one hand, because many years of experience in this segment enable optimal risk management. On the other hand, the financed properties also provide optimum security. Due to the small size of this business segment, private construction financing was unattractive for major banks for a long time. On the other hand, this division was a core business for regional banks and savings banks. However, as a result of the banking crisis in 2007 and 2008 and the ECB’s ongoing low-interest policy, the private mortgage lending sector is now attractive to all market participants. This is reflected in fiercer competition. The importance of customer communication has therefore also increased in the advertising for new business. Since financial and personnel resources are limited, corporate communications are faced with the challenge of addressing potential customers as efficiently as possible. Communication science has already developed a number of concepts for optimal, integrated communication. These are based on average consumers. Against the background of possible regional deviations in media usage and consumer behaviour, this work explains that banks and savings banks with a regionally defined business area should set different priorities within the communications mix than suprare­gional providers. To this end, a field study was conducted in rural areas of the Nuremberg metro­politan region and analysed using a chi-square test. The study revealed the continuing importance of branches and personal advice, despite increasing digitalisation. At the same time, the necessity of closely networking stationary sales and online offers in rural areas becomes clear.

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