scholarly journals A STUDY ON CARDIOVASCULAR DISEASE PATTERN OF ADMITTED CASES IN NEWLY EMERGED NATIONAL HEART CENTRE

2003 ◽  
Vol 41 (141) ◽  
pp. 284-8 ◽  
Author(s):  
Yuba Raj Limbu ◽  
A Maskey ◽  
Man Bahadur K.C. ◽  
R Malla ◽  
D Sharma ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
Cardiac Arrhythmia ◽  
Hypertensive Heart Disease ◽  
Cardiovascular Death ◽  
Cor Pulmonale ◽  
Disease Pattern ◽  
Rheumatic Heart

Cardiovascular disease is one of the global leading causes of death . Although indeveloped countries overall cardiovascular death is declining due to long term declineof rheumatic heart disease (RHD), cerebro vascular and hypertensive heart disease,heart disease is still the leading cause of death. In developing countries prevalence ofcoronary heart disease (CHD) is in increasing trend and cardiovascular disease patternis changing. Cardiovascular disease pattern of this region is revealed in this study.Total 300 study subjects, admitted from May 2000 to April 2001, 174 (58%) male and126 (42%) female and age ranged from 5 to 83 years were analyzed retrospectively.Proportionate distribution of all admitted cases was calculated and arranged inaccording with sequence order.Rheumatic heart disease was found the commonest, which constituted 27.3%, followedby coronary heart disease (21.7%) and hypertension (20.7%) respectively. Chronicobstructive pulmonary disease (COPD) with cor pulmonale (7.7%) was fourth insequence order then respectively came diabetes mellitus (DM) coexisted with CHD orhypertension, dilated cardiomyopathy (DCM), cardiac arrhythmia without organicheart disease, congenital heart disease, infective endocarditis, rheumatic fever,pericardial effusion etc. Readmission rate within one year was 12.3% and mortalityrate was 2.7%. Conclusion: Rheumatic heart disease is the commonest heart diseasefollowed by coronary heart disease and hypertension. COPD with cor pulmonale,diabetes coexisted with CHD or hypertension, DCM and cardiac arrhythmia withoutorganic heart disease are also common heart diseases.Key Words: Cardiovascular diseases, Disease pattern.

scholarly journals Coronary Heart Disease in Children with Kawasaki Disease : PROCEEDINGS OF THE III. CONFERENCE ON PREVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE

1979 ◽  
Vol 43 (5) ◽  
pp. 469-475 ◽  
Author(s):  
HIROHISA KATO ◽  
SHIGEYUKI KOIKE ◽  
CHIHEI TANAKA ◽  
KAZUOKI YOKOCHI ◽  
FUMIO YOSHIOKA ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Kawasaki Disease ◽  
Rheumatic Fever ◽  
Rheumatic Heart Disease ◽  
Rheumatic Heart

scholarly journals Echocardiographic Profile of Patients in Dhulikhel Hospital, A Medical College Hospital in Nepal

2014 ◽  
Vol 11 (1) ◽  
pp. 13-17
Author(s):  
Sanjaya Humagain ◽  
Ramsundar Twayana ◽  
Rajendra Koju
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Diastolic Dysfunction ◽  
Rheumatic Heart Disease ◽  
Congenital Heart ◽  
Hypertensive Heart Disease ◽  
College Hospital ◽  
Medical College ◽  
Rheumatic Heart

Background and Aim : Echocardiograph is an important diagnostic tool to evaluate cardiac disease and is indispensible for management. So it is important to know the spectrum of cardiac abnormalities that can be detected by echocardiograph and the frequency of these findings may vary depending on where the echocardiogram is performed. Aim of this study was to find out the spectrum of echocardiographic finding in different age group in a medical college hospital. Methods and materials : A retrospective observational study was done to at Dhulikhel Hospital to review Echocardiographic profile of 3310 patients who were indicated for echocardiogram over a period of 3 years. Data collected from echocardiograph report registry. Data analysis was done using SPSS 17. Result : Congenital Heart Disease(CHD) (37.74%),Normal finding( 21.19%), Pericardial Heart Disease(19.21%) and Rheumatic Heart Disease(RHD)(17.88%) were the echocardiographic finding in children. In adolescents and young adults Rheumatic Heart Disease (49.90%), Hypertensive Heart Disease (13.34%), Congenital Heart Disease (6.58%), and Pericardial Disease (4.38%) were found. Most common finding in middle age was cor-pulmonale (34.76%) followed by Diastolic Dysfunction (20.60%), Hypertensive Heart Disease(17.06%),Ischemic Heart Disease(IHD) (12.80%). In elderly age most common finding was Diastolic Dysfunction (57.14%). Conclusion : The spectrum of echocardiograph finding in a medical college hospital ranges from Congenital Heart Disease, Rheumatic Heart Disease, Ischemic Heart Disease ,Pericardial disease, Corpulmonale, Diastolic Dysfunction, systolic dysfunction and degenerative valve disease. Streptococcal sore throat leading to Rheumatic Heart Disease and complication of tuberculosis and parasitic infestation leading to pericardial diseases, as well as Hypertensive Heart Disease, and Ischemic Heart Disease constitutes burden in Nepal. Cor-pulmonale and ) Sanjaya Humagain, Ramsundar Twayana, Rajendra Koju. DOI: http://dx.doi.org/10.3126/njh.v11i1.10976   Nepalese Heart Journal 2014;11(1): 13-17

Impact of heart disease on maternal, fetal and neonatal outcomes in a low-resource setting

Heart ◽  
2018 ◽  
Vol 105 (10) ◽  
pp. 755-760 ◽  
Author(s):  
Andrea Beaton ◽  
Emmy Okello ◽  
Amy Scheel ◽  
Alyssa DeWyer ◽  
Renny Ssembatya ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
Pregnancy Outcomes ◽  
Attributable Risk ◽  
Case Finding ◽  
Adverse Pregnancy Outcomes ◽  
Active Case Finding ◽  
Adverse Pregnancy ◽  
Rheumatic Heart

BackgroundThe burden of pre-existing cardiovascular disease and the contribution to adverse pregnancy outcomes are not robustly quantified, particularly in low-income countries. We aimed to determine both the prevalence of maternal heart disease through active case finding and its attributable risk to adverse pregnancy outcomes.MethodsWe conducted a 24-month prospective longitudinal investigation in three Ugandan health centres, using echocardiography for active case finding during antenatal care. Women with and without heart disease were followed to 6 weeks post partum to determine pregnancy outcomes. Prevalence of heart disease was calculated. Per cent attributable risk estimates were generated for maternal, fetal and neonatal mortality.ResultsScreening echocardiography was performed in 3506 women. The prevalence of heart disease was 17 per 1000 women (95% CI 13 to 21); 15 per 1000 was rheumatic heart disease. Only 3.4% of women (2/58) had prior diagnosis. Cardiovascular complications occurred in 51% of women with heart disease, most commonly heart failure. Per cent attributable risk of heart disease on maternal mortality was 88.6% in the exposed population and 10.8% in the overall population. Population attributable risk of heart disease on fetal death was 1.1% and 6.0% for neonatal mortalityConclusionsOccult maternal heart disease may be responsible for a substantial proportion of adverse pregnancy outcomes in low-resource settings. Rheumatic heart disease is, by far, the most common condition, urging global prioritisation of this neglected cardiovascular disease.

scholarly journals A Case: Optimal Treatment of Pregnancy with Rheumatic Heart Disease

2020 ◽  
pp. 1-6
Author(s):  
Rahayu oktaliani ◽  
◽  
Eka D ◽  
Keyword(s):  
Cardiovascular Disease ◽  
Heart Disease ◽  
Maternal Mortality ◽  
Rheumatic Heart Disease ◽  
Optimal Treatment ◽  
Cardiac Complications ◽  
Valvular Lesions ◽  
Rheumatic Heart

The number of women who have a pre-existing cardiovascular disease (CVD) or develop cardiac problems during pregnancy is increasing, and it is the leading cause of non-obstetric mortality during pregnancy. Heart disease complicates approximately 1–3% of pregnancies and is responsible for 10 to 15% of maternal mortality. The rheumatic heart disease remains the number one worldwide cause of maternal cardiac complications in pregnant. It is important that obstetric, anesthesiologists, cardiologist, remain aware of the disease, its complications and management of valvular lesions throughout the birthing process.

scholarly journals DECREASE IN SERUM BILIRUBIN AS AN UNFAVORABLE MARKER OF CARDIOVASCULAR DISORDERS

2020 ◽  
Vol 8 (3) ◽  
pp. 268-275
Author(s):  
L. M. Strilchuk ◽  
O. O. Zimba ◽  
I. B. Zhakun
Keyword(s):  
Oxidative Stress ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Angina Pectoris ◽  
Rheumatic Fever ◽  
Rheumatic Heart Disease ◽  
Serum Bilirubin ◽  
Function Parameter ◽  
Pubmed Database ◽  
Rheumatic Heart

Serum bilirubin, the end product of heme metabolism, is a routine biochemical parameter. Bilirubin is not a liver function parameter exclusively: its concentration correlates with ischemic heart disease (IHD) risk, estimated glomerular filtration rate, retinopathy or neuropathy in diabetes mellitus, atherosclerosis etc. The aim of this paper was to estimate the clinical value of bilirubin analysis according to literature data and own clinical observations in patients with IHD and acute and chronic rheumatologic diseases. Materials and methods. We conducted a literature overview in Pubmed database and domestic sources and also analyzed the standard examinaions of 515 patients: 353 patients with coronary heart disease (acute forms, coronary bypass grafting – 98; acute myocardial infarction, pharmacotherapy – 75; unstable angina pectoris – 101; stable angina pectoris – 79) and 162 rheumatologic patients (haemorrhagic vasculitis – 71; rheumatic fever – 57; chronic rheumatic heart disease with valvular defects – 34). Control group consisted of 22 patients with gastroduodenal zone diseases without helicobacter (esophagitis, gastritis, peptic ulcer). Results and discussion. It was revealed that in case of diseases with oxidative stress in their pathogenesis (acute forms of coronary heart disease, haemorrhagic vasculitis, rheumatic fever) bilirubin level was lower than in case of non-oxidative disorders (non-infectious esophagitis, gastritis, ulcer). Increase of inflammation potency was accompanied by bilirubin decrease. Correlation analysis showed that both bilirubin increase and decrease were unfavourable. Conclusions. Bilirubin concentration correlated with parameters of cytolysis, intoxication, anemia, inflammation, carbohydrate and lipid metabolism, heart structure. Bilirubin decrease associated with the increase of stenosis of coronary arteries (left, left circumflex and anterior interventricular) in a logarithmic way. Hypobilirubinemia (< 9.6 mkmol/L) significantly more often accompanied diseases with oxidative stress in pathogenesis, acute forms and more active systemic inflammation. Keywords total bilirubin, hypobilirubinemia, coronary heart disease, haemorrhagic vasculitis, rheumatic fever, chronic rheumatic heart disease.

P3639Vascular endothelial growth factor-C and mortality in patients with suspected but no history of coronary heart disease: a subanalysis of the ANOX study

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
T Unoki ◽  
M Suzuki ◽  
M Matsuda ◽  
Y Ajiro ◽  
T Shinozaki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cardiovascular Events ◽  
Cardiovascular Death ◽  
All Cause Mortality ◽  
History Of ◽  
Factor C ◽  
Endothelial Growth Factor

Abstract Background The lymphatic system has been suggested to play an important role in cholesterol metabolism and cardiovascular disease. Recently, we demonstrated that serum levels of vascular endothelial growth factor-C (VEGF-C), a central player of lymphangiogenesis, are inversely and independently associated with the risk of all-cause mortality in patients with suspected or known coronary heart disease (CHD). However, the prognostic value of VEGF-C in patients with suspected but no history of CHD is still unclear. Methods Serum VEGF-C levels were measured in 1,717 patients with suspected but no history of CHD undergoing elective coronary angiography, enrolled in the development of novel biomarkers related to angiogenesis or oxidative stress to predict cardiovascular events (ANOX) study, and followed up for 3 years. The primary outcome was all-cause death. The secondary outcomes were cardiovascular death, and major adverse cardiovascular events (MACE) defined as a composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke. Results During the follow-up, 161 patients died from any cause, 50 died from cardiovascular disease, and 104 developed MACE. After adjustment for established risk factors, VEGF-C levels were significantly and inversely associated with all-cause death (hazard ratio [HR] for 1-SD increase, 0.69; 95% confidence interval [CI], 0.58–0.83) and cardiovascular death (HR, 0.72; 95% CI, 0.52–0.998), but not with MACE (HR, 0.91; 95% CI, 0.74–1.13). Even after incorporation of N-terminal pro-brain natriuretic peptide, contemporary sensitive cardiac troponin-I, and high-sensitivity C-reactive protein into a model with established risk factors, the addition of VEGF-C levels further improved the prediction of all-cause death (continuous net reclassification improvement [NRI], 0.282; 95% CI, 0.121–0.443; P<0.001; integrated discrimination improvement [IDI], 0.009; 95% CI, 0.003–0.016; P=0.005), but not that of cardiovascular death (NRI, 0.178; 95% CI, r=−0.103–0.458; P=0.214; IDI, 0.004; 95% CI, r=−0.002–0.009; P=0.194) or MACE (NRI, 0.037; 95% CI, r=−0.162–0.235; P=0.717; IDI, 0.000; 95% CI, r=−0.0004–0.0005; P=0.872). Conclusions In patients with suspected but no history of CHD undergoing elective coronary angiography, a low VEGF-C value may predict all-cause mortality independent of established risk factors and cardiovascular biomarkers. Acknowledgement/Funding The ANOX study is supported by a Grant-in-Aid for Clinical Research from the National Hospital Organization

scholarly journals Heart Failure Study: Profile of Heart Failure Admissions in Medical Intensive Care Unit

2017 ◽  
Vol 6 (1) ◽  
pp. 32-34 ◽  
Author(s):  
Shyam Raj Regmi ◽  
Arun Maskey ◽  
Laxman Dubey
Keyword(s):  
Heart Failure ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
Medical Intensive Care Unit ◽  
Cor Pulmonale ◽  
Cardiac Lesion ◽  
Medical Intensive Care ◽  
Rheumatic Heart

Heart failure (HF) is a major cause of morbidity and mortality all over the world. In developed countries because of aging population and increased prevalence of coronary artery disease, heart failure has attained epidemic proportions, whereas, in developing countries like Nepal, rheumatic heart dissease is still the commonest cause of HF admission in medical intensive care unit (MICU). A retrospective study analysing registered data of HF admissions in MICU of Shahid Gangalal National Heart Centre (SGNHC) from August 2002 to OCtober 2008. Among these, 1771 patients were admitted for management of HF and were included in this study. Mean age was 45.07 Å} 35.09 (ranges from 11 years to 95 years). 836 (47%) were male and 935 (53%) were female. Rheumatic heart disease causing valvular cardiac lesion leading to HF was found in 791 (45%) patients. Dilated cardiomyopathy in 424 (24%), Ischemic heart disease in 378 (1%), hypertensive heart failure in 101 (6%) and HG due to congenital heart disease was found in 43 (2%) patients, Though, HF due to COPD / Cor-pulmonale is usually discouraged to be admitted in this heart centre, still 34(2%) patients were admitted for the management of HF due to COPD/cor-pulmonale. Rheumatic heart disease causing valvular cardiac lesion leading to HF admission was still the commonest cause of HF admission in MICU in our heart centre. Despite ACC/AHA guideline suggesting use of beta-blocking agent in patients with heart failure, only 22% of our patients received that agent. Thus, many patients were not being managed fully in accordance with international evidence based guidelines.

scholarly journals Upaya Peningkatan Pengetahuan tentang Penyakit Jantung Koroner pada Lansia di Posyandu Lansia Kelurahan Rawasari

2021 ◽  
Vol 3 (3) ◽  
pp. 249
Author(s):  
Marta Suri
Keyword(s):  
Cardiovascular Disease ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Health Education ◽  
Coronary Vessels ◽  
The Elderly ◽  
Whole Body ◽  
Preventive Effort ◽  
High Incidence ◽  
Rheumatic Heart

Coronary heart disease is caused by various factors that can cause an increase in the incidence / deposits of cholesterol which narrow the vessels in the whole body including the coronary vessels. Coronary heart disease has become the leading cause of death in Indonesia. According to WHO in 2005, the number of deaths from cardiovascular disease (especially coronary heart disease, stroke, and rheumatic heart disease) increased globally to 17.5 million from 14.4 million in 1990. The results of the situation have been obtained from RT 12 KelurahanRawasariKecamatanAlamBarajo, Jambi City, in this sub-districthealth services such as Intregated Service Post (Posyandu) have been established. However, there is no scheduled health education as a promotive and preventive effort to overcome the problem of the high incidence of people experiencing heart disease. The results of health education activities for the elderly are expected to understand the concept of nursing problems that cause coronary heart disease

Cardiovascular Disease in Developing Countries Rheumatic Heart Disease

Cardiology ◽  
1984 ◽  
pp. 657-670
Author(s):  
S. Padmavati ◽  
Vineeta Vishvbandhu ◽  
Vijay Gupta ◽  
K. Prakash
Keyword(s):  
Cardiovascular Disease ◽  
Developing Countries ◽  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
Rheumatic Heart

scholarly journals Prevalence of rheumatic heart disease in a major referral cardiology clinic in Ethiopia: A retrospective cross-sectional study

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246519
Author(s):  
Melkamu H. Asmare ◽  
Frehiwot Woldehanna ◽  
Samuel Hunegnaw ◽  
Luc Janssens ◽  
Bart Vanrumste
Keyword(s):  
Heart Disease ◽  
Rheumatic Heart Disease ◽  
Urban Areas ◽  
Hypertensive Heart Disease ◽  
Cross Sectional Study ◽  
Interquartile Range ◽  
Age Group ◽  
Cross Sectional ◽  
Working Age ◽  
Rheumatic Heart

Background Rheumatic Heart Disease (RHD) remains one of the major causes of death and disability in developing countries. This preventable, treatable but not curable form of cardiovascular disease is needlessly killing scores of children and youth mainly due to the misunderstanding of the burden of the disease in these countries. We sought to describe the prevalence of RHD at one of the major referral cardiology clinics in Ethiopia. Methods This was a retrospective cross-sectional chart review of all patients referred for a cardiopathy at the Tikur Anbessa Referral Cardiac Clinic from June 2015 to August 2018. We excluded records of patients with a non-cardiac diagnosis and those without a clear diagnosis. A predesigned and tested EXCEL form was used to collect the data. The data was encoded directly from the patient record files. MATLAB’s statistics toolbox (MATLAB2019b) was used for statistical analysis. Results Among the total 7576 records analyzed 59.5% of the patients were women. 83.1% of the data belonged to adult patients with the largest concentration reported in the 18 to 27 age group. 69.7% of the patients were from urban areas. The median age of the study population was 30 (interquartile range = 21–50). 4151 cases were caused by RHD which showed that RHD constituted 54.8% of the cases. The median age for RHD patients was 25 (interquartile range = 19–34). The second most prevalent disease was hypertensive heart disease which constituted 13.6% that was followed by congenital heart disease with 9% prevalence rate. Conclusion The results of this study indicated the extent of the RHD prevalence in Ethiopia’s cardiac hospital was 54.8%. What was more critical was that almost 70% of the RHD patients were mainly the working-age group(19 to 34 years).

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