Date palm fruit extract attenuated oxidative stress induced by two haloacetic acids in Wistar rats

2017 ◽  
Vol 10 (2) ◽  
pp. 141-152
Author(s):  
Amira El Arem ◽  
Emna Behija Saafi ◽  
Lamia Lahouar ◽  
Amira Thouri ◽  
Fatma Ghrairi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Wistar Rats ◽  
Date Palm ◽  
Haloacetic Acids ◽  
Fruit Extract ◽  
Palm Fruit

Protective effect of date palm fruit extract (Phoenix dactylifera L.) on dimethoate induced-oxidative stress in rat liver

2011 ◽  
Vol 63 (5) ◽  
pp. 433-441 ◽  
Author(s):  
Emna Behija Saafi ◽  
Mouna Louedi ◽  
Abdelfattah Elfeki ◽  
Abdelfattah Zakhama ◽  
Mohamed Fadhel Najjar ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Rat Liver ◽  
Date Palm ◽  
Phoenix Dactylifera ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Phoenix Dactylifera L

Antioxidant-rich date palm fruit extract inhibits oxidative stress and nephrotoxicity induced by dimethoate in rat

2011 ◽  
Vol 68 (1) ◽  
pp. 47-58 ◽  
Author(s):  
Emna Behija Saafi-Ben Salah ◽  
Amira El Arem ◽  
Mouna Louedi ◽  
Mongi Saoudi ◽  
Abdelfattah Elfeki ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Date Palm ◽  
Fruit Extract ◽  
Palm Fruit

scholarly journals CARDIOPROTECTIVE EFFECT OF DATE PALM AGAINST DOXORUBICIN-INDUCED CARDIOTOXICITY

2018 ◽  
Vol 11 (7) ◽  
pp. 141 ◽  
Author(s):  
Shimaa Mubarak ◽  
Shadia Abdel Hamid ◽  
Abdel Razik Farrag ◽  
Nahla Samir ◽  
Jihan Seid Hussein
Keyword(s):  
Date Palm ◽  
Cardiac Tissue ◽  
Density Lipoprotein ◽  
Heart Tissue ◽  
Lipoprotein Cholesterol ◽  
Medical Community ◽  
Albino Rats ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Creatine Kinase Mb

Objective: Doxorubicin (Dox), an anthracycline antibiotic, has been widely used to treat cancer, principally hematological malignancies, and solid tumors. The administration of Dox is a topic of concern in the medical community, as it frequently related to dose-dependent cardiotoxicity. Therefore, the present study was designed to investigate the protective potential of date palm fruit extract on Dox-induced cardiotoxicity.Methods: A total of 40 female albino rats were used in this study and classified into four groups including control, date palm fruit extract, Dox, and treated date palm fruit extract groups.Results: Dox produced a significant increase in creatine kinase-MB and lactate dehydrogenase activities. It also decreased the activities of cardiac glutathione peroxidase and superoxide dismutase but increase levels of cardiac malondialdehyde and also of urinary 8-hydroxy-2-deoxyguanosine. Myocardial toxicity of Dox also appeared in the elevation of serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while level of high-density lipoprotein cholesterol decreased. Histopathological studies revealed alteration of cardiac tissue structure by Dox. Treatment with date palm fruit extract restored the aforementioned parameters.Conclusion: Date palm fruit exhibits a cardioprotective influence on the heart tissue against toxicity induced by Dox.

scholarly journals PHOENIX DACTYLIFERA FRUIT EXTRACT AMELIORATES ALTERED BIOCHEMICAL PARAMETERS IN STREPTOZOTOCIN-INDUCED DIABETES MELLITUS ALBINO RATS

2020 ◽  
pp. 27-31
Author(s):  
OGO A. O. ◽  
ABAH S. F. ◽  
INALEGWU B. ◽  
ERU U. E.
Keyword(s):  
Diabetes Mellitus ◽  
Biochemical Parameters ◽  
Date Palm ◽  
Diabetic Control ◽  
Alternative Methods ◽  
Control Group ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Positive Effects ◽  
Group I

Objective: Consistent projections have indicated a steady increase in the global burden of diabetes mellitus. Given the increased cost in conventional management of the condition in addition to reported side effects and cost of orthodox management, attention is shifting to the use of alternative methods such as plants materials with dual benefits as food and medicine. Thus, this study was designed to investigate the effect of date palm fruit on some biochemical parameters in streptozotocin-induced wistar rats. Methods: Animals were divided into 5 groups of 6 rats each (I as normal control, II as diabetic control and 3-5 as extract-treated groups) maintained for 14 d. At the end of the treatment, the animals were fasted overnight, then sacrificed and blood samples collected for analysis of biochemical parameters (including blood glucose, blood lipids and enzymes). Results: The results show that treatment of diabetic animals with extract of date palm fruit show a significant (P<0.05) reduction in glucose levels in groups II–V compared to group I. Similar positive effects were observed in the levels of lipids and enzymes in treated groups compared to diabetic control group II. A GC-MS analysis of the fraction of the fruit extract revealed some bioactive compounds that may be responsible for the effects exhibited in the study. Conclusion: These findings which demonstrate the ameliorative effect on hyperglycemia and hyperlipidemia, further support the use of date palm fruit as a nutraceutical agent.

scholarly journals ANTI-INFERTILITY EFFECTS TEST OF DATE PALM FRUIT EXTRACT (PHOENIX DACTYLIFERA L.) IN FEMALE MICE (MUS MUSCULUS) COMPARED WITH PROPOLIS

2018 ◽  
Vol 11 (11) ◽  
pp. 433
Author(s):  
Dwisari Dillasamola ◽  
Almahdy A ◽  
Ria Anggraini ◽  
Skunda Diliarosta ◽  
Biomechy Oktomalio P ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Date Palm ◽  
Endometrial Thickness ◽  
Ethanol Extract ◽  
Phoenix Dactylifera ◽  
Ovarian Follicles ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Date Fruit ◽  
Phoenix Dactylifera L

Objective: The date palm (Phoenix dactylifera L) is one of the plants empirically used to increase fertility. The aim of this study was to compare the effect of ethanol extract of date palm fruit and propolis on fertility in female mice.Methods: 5 groups were assigned to 1 control and 4 experimental groups. The experimental group treated by oral administration of 100, 200 and 400 mg/kgBW of khalal date fruit extract and 200 mg/kgBW of propolis for 5, 10 and 15 days. Control groups received no extract. After 5, 10 and 15 days the mice were deeply anesthetized with anesthetic ether and sacrificed. Histological changes in ovary and uterine were measured. The data was analyzed by using two way ANOVA and Duncan test.Results: The results of the study of the effect of the dose and duration of the ethanol extract of khalal date fruit on the histology of ovaries and uterine mice showed that there was an increase in the number of primary, secondary, tertiary, degraaf, and corpus luteum follicles but did not affect the follicle of atresia and myometrial and endometrial thickness. in Propolis a dose of 100mg / kgBW increase occurs only in primary, secondary and corpus luteum follicles.Conclusion: Ethanol extract of khalal date fruit and Propolis can increase the number of ovarian follicles. Ethanol extract of khalal date fruit dose can increase the number of ovarian follicles higher than propolis.

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