scholarly journals POSSIBLE EFFECT OF DATE PALM FRUIT EXTRACT ON SOMEBIOCHEMICAL AND HEMATOLOGICAL PARAMETERS IN RATS INTOXICATED WITH METHOMYLINSECTICIDE

2018 ◽  
Vol 29 (Issue 1-C) ◽  
pp. 35-46
Keyword(s):  
Date Palm ◽  
Hematological Parameters ◽  
Fruit Extract ◽  
Palm Fruit

scholarly journals CARDIOPROTECTIVE EFFECT OF DATE PALM AGAINST DOXORUBICIN-INDUCED CARDIOTOXICITY

2018 ◽  
Vol 11 (7) ◽  
pp. 141 ◽  
Author(s):  
Shimaa Mubarak ◽  
Shadia Abdel Hamid ◽  
Abdel Razik Farrag ◽  
Nahla Samir ◽  
Jihan Seid Hussein
Keyword(s):  
Date Palm ◽  
Cardiac Tissue ◽  
Density Lipoprotein ◽  
Heart Tissue ◽  
Lipoprotein Cholesterol ◽  
Medical Community ◽  
Albino Rats ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Creatine Kinase Mb

Objective: Doxorubicin (Dox), an anthracycline antibiotic, has been widely used to treat cancer, principally hematological malignancies, and solid tumors. The administration of Dox is a topic of concern in the medical community, as it frequently related to dose-dependent cardiotoxicity. Therefore, the present study was designed to investigate the protective potential of date palm fruit extract on Dox-induced cardiotoxicity.Methods: A total of 40 female albino rats were used in this study and classified into four groups including control, date palm fruit extract, Dox, and treated date palm fruit extract groups.Results: Dox produced a significant increase in creatine kinase-MB and lactate dehydrogenase activities. It also decreased the activities of cardiac glutathione peroxidase and superoxide dismutase but increase levels of cardiac malondialdehyde and also of urinary 8-hydroxy-2-deoxyguanosine. Myocardial toxicity of Dox also appeared in the elevation of serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while level of high-density lipoprotein cholesterol decreased. Histopathological studies revealed alteration of cardiac tissue structure by Dox. Treatment with date palm fruit extract restored the aforementioned parameters.Conclusion: Date palm fruit exhibits a cardioprotective influence on the heart tissue against toxicity induced by Dox.

Protective effect of date palm fruit extract (Phoenix dactylifera L.) on dimethoate induced-oxidative stress in rat liver

2011 ◽  
Vol 63 (5) ◽  
pp. 433-441 ◽  
Author(s):  
Emna Behija Saafi ◽  
Mouna Louedi ◽  
Abdelfattah Elfeki ◽  
Abdelfattah Zakhama ◽  
Mohamed Fadhel Najjar ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Rat Liver ◽  
Date Palm ◽  
Phoenix Dactylifera ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Phoenix Dactylifera L

scholarly journals The beneficial effect of natural antioxidants from olive oil with fig and date palm fruit extracts on biochemical and hematological parameters in rats during diethylnitrosamine-induced carcinogenesis

FACETS ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 584-597 ◽  
Author(s):  
Abdallah H. Fathy ◽  
Mohamed A. Bashandy ◽  
Samir A. Bashandy ◽  
Ahmed M. Mansour
Keyword(s):  
Olive Oil ◽  
Date Palm ◽  
Hematological Parameters ◽  
Thiobarbituric Acid ◽  
Natural Antioxidants ◽  
Treated Group ◽  
Palm Fruit ◽  
Fruit Extracts ◽  
Male Wistar Rats ◽  
Nitric Oxide Concentration

Diethylnitrosamine (DEN) is a well-known carcinogen. The aim of our study was to determine the role of olive oil (7 g/kg) with fig (1 g/kg) (OF) and (or) date palm (1 g/kg) (D) fruit extracts during DEN treatment of male Wistar rats. The OF–DEN and (or) D–DEN groups were given oral antioxidants daily for two weeks before and during DEN treatment (21 weeks).The DEN-treated group showed dramatic results for all investigated parameters as compared with the control rats. All OF–DEN and D–DEN groups showed significant improvement in hepatic thiobarbituric acid reactive substances, reduced glutathione, and nitric oxide concentration in the liver tissue, in addition to improvement in serum vascular endothelial growth factor level, alpha-fetoprotein, lipid profile, lipid risk ratios, and the hematological parameters as compared with the DEN-treated group.In conclusion, the administration of OF and (or) D fruit extracts to DEN-treated rats resulted in a considerable improvement in the investigated biochemical and hematological parameters. In addition, the combined OFD treatments showed greater improvements revealing the synergistic effect of the combination.

Antioxidant-rich date palm fruit extract inhibits oxidative stress and nephrotoxicity induced by dimethoate in rat

2011 ◽  
Vol 68 (1) ◽  
pp. 47-58 ◽  
Author(s):  
Emna Behija Saafi-Ben Salah ◽  
Amira El Arem ◽  
Mouna Louedi ◽  
Mongi Saoudi ◽  
Abdelfattah Elfeki ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Date Palm ◽  
Fruit Extract ◽  
Palm Fruit

scholarly journals The beneficial effect of natural antioxidants from olive oil with fig and date palm fruit extracts on biochemical and hematological parameters in rats treated with doxorubicin and γ-radiation

FACETS ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 722-735 ◽  
Author(s):  
Abdallah H. Fathy ◽  
Mohamed A. Bashandy ◽  
Samir A.E. Bashandy ◽  
Ahmed M. Mansour ◽  
Khaled S. Azab
Keyword(s):  
Beneficial Effect ◽  
Lipid Profile ◽  
Olive Oil ◽  
Date Palm ◽  
Hematological Parameters ◽  
Experimental Period ◽  
Whole Body ◽  
Palm Fruit ◽  
Γ Radiation ◽  
Risk Ratios

The goal of this study was to determine the possible beneficial effect of olive oil (7 g/kg) with fig (1 g/kg) and date palm fruit (1 g/kg) extracts (OFD) on the toxicity hazards of doxorubicin (DOX) and (or) γ-radiation. The DOX-treated groups received doses of 2.5 mg/kg body weight via intravenous (IV) injection weekly for four consecutive weeks. Rats in the irradiated groups were exposed to whole-body γ-radiation with fractioned doses of 2 Gy weekly for four consecutive weeks. The OFD-treated groups received two weeks of pretreatment with OFD and daily supplementation via oral gavage during the experimental period. The DOX-treated and (or) irradiated groups showed decreases in the antioxidant parameters (reduced glutathione and nitric oxide) as well as increased lipid peroxidation products. In addition, we observed changes in the lipid profile parameters, lipid risk ratios, and hematological values (erythrocyte (RBC) count, hemoglobin (Hb) concentration, hematocrit (Hct) percentage, platelet count, and total and differential leukocyte (WBC) count) in these groups compared with the control rats. The administration of OFD to DOX-treated and (or) irradiated rats significantly ameliorated the oxidative stress markers, lipid profile, risk ratios, and hematological parameters. In conclusion, OFD could be used synergistically to decrease the negative side effects of chemotherapy and radiotherapy.

scholarly journals PHOENIX DACTYLIFERA FRUIT EXTRACT AMELIORATES ALTERED BIOCHEMICAL PARAMETERS IN STREPTOZOTOCIN-INDUCED DIABETES MELLITUS ALBINO RATS

2020 ◽  
pp. 27-31
Author(s):  
OGO A. O. ◽  
ABAH S. F. ◽  
INALEGWU B. ◽  
ERU U. E.
Keyword(s):  
Diabetes Mellitus ◽  
Biochemical Parameters ◽  
Date Palm ◽  
Diabetic Control ◽  
Alternative Methods ◽  
Control Group ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Positive Effects ◽  
Group I

Objective: Consistent projections have indicated a steady increase in the global burden of diabetes mellitus. Given the increased cost in conventional management of the condition in addition to reported side effects and cost of orthodox management, attention is shifting to the use of alternative methods such as plants materials with dual benefits as food and medicine. Thus, this study was designed to investigate the effect of date palm fruit on some biochemical parameters in streptozotocin-induced wistar rats. Methods: Animals were divided into 5 groups of 6 rats each (I as normal control, II as diabetic control and 3-5 as extract-treated groups) maintained for 14 d. At the end of the treatment, the animals were fasted overnight, then sacrificed and blood samples collected for analysis of biochemical parameters (including blood glucose, blood lipids and enzymes). Results: The results show that treatment of diabetic animals with extract of date palm fruit show a significant (P<0.05) reduction in glucose levels in groups II–V compared to group I. Similar positive effects were observed in the levels of lipids and enzymes in treated groups compared to diabetic control group II. A GC-MS analysis of the fraction of the fruit extract revealed some bioactive compounds that may be responsible for the effects exhibited in the study. Conclusion: These findings which demonstrate the ameliorative effect on hyperglycemia and hyperlipidemia, further support the use of date palm fruit as a nutraceutical agent.

scholarly journals ANTI-INFERTILITY EFFECTS TEST OF DATE PALM FRUIT EXTRACT (PHOENIX DACTYLIFERA L.) IN FEMALE MICE (MUS MUSCULUS) COMPARED WITH PROPOLIS

2018 ◽  
Vol 11 (11) ◽  
pp. 433
Author(s):  
Dwisari Dillasamola ◽  
Almahdy A ◽  
Ria Anggraini ◽  
Skunda Diliarosta ◽  
Biomechy Oktomalio P ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Date Palm ◽  
Endometrial Thickness ◽  
Ethanol Extract ◽  
Phoenix Dactylifera ◽  
Ovarian Follicles ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Date Fruit ◽  
Phoenix Dactylifera L

Objective: The date palm (Phoenix dactylifera L) is one of the plants empirically used to increase fertility. The aim of this study was to compare the effect of ethanol extract of date palm fruit and propolis on fertility in female mice.Methods: 5 groups were assigned to 1 control and 4 experimental groups. The experimental group treated by oral administration of 100, 200 and 400 mg/kgBW of khalal date fruit extract and 200 mg/kgBW of propolis for 5, 10 and 15 days. Control groups received no extract. After 5, 10 and 15 days the mice were deeply anesthetized with anesthetic ether and sacrificed. Histological changes in ovary and uterine were measured. The data was analyzed by using two way ANOVA and Duncan test.Results: The results of the study of the effect of the dose and duration of the ethanol extract of khalal date fruit on the histology of ovaries and uterine mice showed that there was an increase in the number of primary, secondary, tertiary, degraaf, and corpus luteum follicles but did not affect the follicle of atresia and myometrial and endometrial thickness. in Propolis a dose of 100mg / kgBW increase occurs only in primary, secondary and corpus luteum follicles.Conclusion: Ethanol extract of khalal date fruit and Propolis can increase the number of ovarian follicles. Ethanol extract of khalal date fruit dose can increase the number of ovarian follicles higher than propolis.

Date palm fruit extract attenuated oxidative stress induced by two haloacetic acids in Wistar rats

2017 ◽  
Vol 10 (2) ◽  
pp. 141-152
Author(s):  
Amira El Arem ◽  
Emna Behija Saafi ◽  
Lamia Lahouar ◽  
Amira Thouri ◽  
Fatma Ghrairi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Wistar Rats ◽  
Date Palm ◽  
Haloacetic Acids ◽  
Fruit Extract ◽  
Palm Fruit

Emergence of New Potential Insect Pests of Date Palm: Could Climate Change Be the Reason?

2019 ◽  
Vol 30 (6) ◽  
pp. 242-245
Author(s):  
Hamadttu A. F. El-Shafie
Keyword(s):  
Climate Change ◽  
Date Palm ◽  
Insect Pests ◽  
Anthropogenic Activities ◽  
Economic Damage ◽  
South American ◽  
Palm Fruit ◽  
The Family ◽  
American Palm ◽  
Sorghum Chafer

Four insect species were reported as new potential pests of date palm in recent years. They are sorghum chafer (Pachnoda interrupta), the rose chafer (Potosia opaca), the sericine chafer beetle (Maladera insanablis), and the South American palm borer (Pysandisia archon). The first three species belong to the order Coleoptera and the family Scarabaeidae, while the fourth species is a lepidopteran of the family Castniidae. The injury as well as the economic damage caused by the four species on date palm need to be quantified. Due to climate change and anthropogenic activities, the date palm pest complex is expected to change in the future. To the author's knowledge, this article provides the first report of sorghum chafer as a pest damaging date palm fruit.

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