Date palm fruit extract ameliorated pancreatic apoptosis, endocrine dysfunction and regulatory inflammatory cytokines in Streptozotocin-induced diabetes in rats

2020 ◽  
Vol 27 (34) ◽  
pp. 43322-43339
Author(s):  
Mona H. Hafez ◽  
Samar S. Elblehi ◽  
Yasser S. El-Sayed
Keyword(s):  
Inflammatory Cytokines ◽  
Date Palm ◽  
Endocrine Dysfunction ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Streptozotocin Induced Diabetes

scholarly journals CARDIOPROTECTIVE EFFECT OF DATE PALM AGAINST DOXORUBICIN-INDUCED CARDIOTOXICITY

2018 ◽  
Vol 11 (7) ◽  
pp. 141 ◽  
Author(s):  
Shimaa Mubarak ◽  
Shadia Abdel Hamid ◽  
Abdel Razik Farrag ◽  
Nahla Samir ◽  
Jihan Seid Hussein
Keyword(s):  
Date Palm ◽  
Cardiac Tissue ◽  
Density Lipoprotein ◽  
Heart Tissue ◽  
Lipoprotein Cholesterol ◽  
Medical Community ◽  
Albino Rats ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Creatine Kinase Mb

Objective: Doxorubicin (Dox), an anthracycline antibiotic, has been widely used to treat cancer, principally hematological malignancies, and solid tumors. The administration of Dox is a topic of concern in the medical community, as it frequently related to dose-dependent cardiotoxicity. Therefore, the present study was designed to investigate the protective potential of date palm fruit extract on Dox-induced cardiotoxicity.Methods: A total of 40 female albino rats were used in this study and classified into four groups including control, date palm fruit extract, Dox, and treated date palm fruit extract groups.Results: Dox produced a significant increase in creatine kinase-MB and lactate dehydrogenase activities. It also decreased the activities of cardiac glutathione peroxidase and superoxide dismutase but increase levels of cardiac malondialdehyde and also of urinary 8-hydroxy-2-deoxyguanosine. Myocardial toxicity of Dox also appeared in the elevation of serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while level of high-density lipoprotein cholesterol decreased. Histopathological studies revealed alteration of cardiac tissue structure by Dox. Treatment with date palm fruit extract restored the aforementioned parameters.Conclusion: Date palm fruit exhibits a cardioprotective influence on the heart tissue against toxicity induced by Dox.

Protective effect of date palm fruit extract (Phoenix dactylifera L.) on dimethoate induced-oxidative stress in rat liver

2011 ◽  
Vol 63 (5) ◽  
pp. 433-441 ◽  
Author(s):  
Emna Behija Saafi ◽  
Mouna Louedi ◽  
Abdelfattah Elfeki ◽  
Abdelfattah Zakhama ◽  
Mohamed Fadhel Najjar ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Rat Liver ◽  
Date Palm ◽  
Phoenix Dactylifera ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Phoenix Dactylifera L

Antioxidant-rich date palm fruit extract inhibits oxidative stress and nephrotoxicity induced by dimethoate in rat

2011 ◽  
Vol 68 (1) ◽  
pp. 47-58 ◽  
Author(s):  
Emna Behija Saafi-Ben Salah ◽  
Amira El Arem ◽  
Mouna Louedi ◽  
Mongi Saoudi ◽  
Abdelfattah Elfeki ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Date Palm ◽  
Fruit Extract ◽  
Palm Fruit

scholarly journals PHOENIX DACTYLIFERA FRUIT EXTRACT AMELIORATES ALTERED BIOCHEMICAL PARAMETERS IN STREPTOZOTOCIN-INDUCED DIABETES MELLITUS ALBINO RATS

2020 ◽  
pp. 27-31
Author(s):  
OGO A. O. ◽  
ABAH S. F. ◽  
INALEGWU B. ◽  
ERU U. E.
Keyword(s):  
Diabetes Mellitus ◽  
Biochemical Parameters ◽  
Date Palm ◽  
Diabetic Control ◽  
Alternative Methods ◽  
Control Group ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Positive Effects ◽  
Group I

Objective: Consistent projections have indicated a steady increase in the global burden of diabetes mellitus. Given the increased cost in conventional management of the condition in addition to reported side effects and cost of orthodox management, attention is shifting to the use of alternative methods such as plants materials with dual benefits as food and medicine. Thus, this study was designed to investigate the effect of date palm fruit on some biochemical parameters in streptozotocin-induced wistar rats. Methods: Animals were divided into 5 groups of 6 rats each (I as normal control, II as diabetic control and 3-5 as extract-treated groups) maintained for 14 d. At the end of the treatment, the animals were fasted overnight, then sacrificed and blood samples collected for analysis of biochemical parameters (including blood glucose, blood lipids and enzymes). Results: The results show that treatment of diabetic animals with extract of date palm fruit show a significant (P<0.05) reduction in glucose levels in groups II–V compared to group I. Similar positive effects were observed in the levels of lipids and enzymes in treated groups compared to diabetic control group II. A GC-MS analysis of the fraction of the fruit extract revealed some bioactive compounds that may be responsible for the effects exhibited in the study. Conclusion: These findings which demonstrate the ameliorative effect on hyperglycemia and hyperlipidemia, further support the use of date palm fruit as a nutraceutical agent.

scholarly journals ANTI-INFERTILITY EFFECTS TEST OF DATE PALM FRUIT EXTRACT (PHOENIX DACTYLIFERA L.) IN FEMALE MICE (MUS MUSCULUS) COMPARED WITH PROPOLIS

2018 ◽  
Vol 11 (11) ◽  
pp. 433
Author(s):  
Dwisari Dillasamola ◽  
Almahdy A ◽  
Ria Anggraini ◽  
Skunda Diliarosta ◽  
Biomechy Oktomalio P ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Date Palm ◽  
Endometrial Thickness ◽  
Ethanol Extract ◽  
Phoenix Dactylifera ◽  
Ovarian Follicles ◽  
Fruit Extract ◽  
Palm Fruit ◽  
Date Fruit ◽  
Phoenix Dactylifera L

Objective: The date palm (Phoenix dactylifera L) is one of the plants empirically used to increase fertility. The aim of this study was to compare the effect of ethanol extract of date palm fruit and propolis on fertility in female mice.Methods: 5 groups were assigned to 1 control and 4 experimental groups. The experimental group treated by oral administration of 100, 200 and 400 mg/kgBW of khalal date fruit extract and 200 mg/kgBW of propolis for 5, 10 and 15 days. Control groups received no extract. After 5, 10 and 15 days the mice were deeply anesthetized with anesthetic ether and sacrificed. Histological changes in ovary and uterine were measured. The data was analyzed by using two way ANOVA and Duncan test.Results: The results of the study of the effect of the dose and duration of the ethanol extract of khalal date fruit on the histology of ovaries and uterine mice showed that there was an increase in the number of primary, secondary, tertiary, degraaf, and corpus luteum follicles but did not affect the follicle of atresia and myometrial and endometrial thickness. in Propolis a dose of 100mg / kgBW increase occurs only in primary, secondary and corpus luteum follicles.Conclusion: Ethanol extract of khalal date fruit and Propolis can increase the number of ovarian follicles. Ethanol extract of khalal date fruit dose can increase the number of ovarian follicles higher than propolis.

Date palm fruit extract attenuated oxidative stress induced by two haloacetic acids in Wistar rats

2017 ◽  
Vol 10 (2) ◽  
pp. 141-152
Author(s):  
Amira El Arem ◽  
Emna Behija Saafi ◽  
Lamia Lahouar ◽  
Amira Thouri ◽  
Fatma Ghrairi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Wistar Rats ◽  
Date Palm ◽  
Haloacetic Acids ◽  
Fruit Extract ◽  
Palm Fruit

Emergence of New Potential Insect Pests of Date Palm: Could Climate Change Be the Reason?

2019 ◽  
Vol 30 (6) ◽  
pp. 242-245
Author(s):  
Hamadttu A. F. El-Shafie
Keyword(s):  
Climate Change ◽  
Date Palm ◽  
Insect Pests ◽  
Anthropogenic Activities ◽  
Economic Damage ◽  
South American ◽  
Palm Fruit ◽  
The Family ◽  
American Palm ◽  
Sorghum Chafer

Four insect species were reported as new potential pests of date palm in recent years. They are sorghum chafer (Pachnoda interrupta), the rose chafer (Potosia opaca), the sericine chafer beetle (Maladera insanablis), and the South American palm borer (Pysandisia archon). The first three species belong to the order Coleoptera and the family Scarabaeidae, while the fourth species is a lepidopteran of the family Castniidae. The injury as well as the economic damage caused by the four species on date palm need to be quantified. Due to climate change and anthropogenic activities, the date palm pest complex is expected to change in the future. To the author's knowledge, this article provides the first report of sorghum chafer as a pest damaging date palm fruit.

The effects of date pollinizer variety and pollination time on fruit set and yield of Medjhol date palm

2014 ◽  
Vol 2 (2) ◽  
pp. 67-71 ◽  
Author(s):  
Abdoul Amir Rahnama ◽  
Esmaeil Rahkhodaei
Keyword(s):  
Date Palm ◽  
Fruit Set ◽  
Block Design ◽  
Male Flower ◽  
Fruit Weight ◽  
Palm Fruit ◽  
Tropical Fruit ◽  
Male And Female ◽  
Time Interaction ◽  
Female Flowers

Date palm is unisexual, being either male or female. Male and female flowers grow on buds called Spathe, which opens naturally when fully mature. It is easy to identify the male and female flowers. Under the method of manual pollination, pollen from a male flower is smeared over female flowers. The pollen variety and pollination time have important effects on date palm fruit set, yield and quality. This experiment was carried out to study the effect of date pollinizer variety and pollination time on fruit set, growth and development of Medjhol date palm variety, in date palm garden of date palm and tropical fruit research institute of Iran during three years from 2009 to 2011. The trail was randomized complete block design in factorial manner with three pollen variety as Ghaname, Vardy, and Samesmave, two pollination time as 1-3 days before or after spathe opening and four replication. The results showed that the Vardy pollen had significant effects and increased the fertility percent and fruit yield, rather than two other pollen varieties. The pollen variety had no significant effects on fruit quality as total sugar, acidity, and bricx. The pollination time before spathe opening significantly increased fertility percent, decreased fruit weight and date palm yield. Finally the pollen variety and pollination time interaction effects showed that, application of Vardy pollen from 1-3 days after spathe opening with the most production date palm yield, equal 19.9 kilogram per any date palm trees, so this treatment is the best and are recommended.

The Effect of Feeding Date Palm Fruit (Phoeix dactylifera L.) on Energy, Macronutrient, and Fiber Intakes of a Convenient Sample of Females

2020 ◽  
Vol 16 (8) ◽  
pp. 1270-1277
Author(s):  
Hiba F. Al-Sayyed ◽  
Hamed R. Takruri ◽  
Nawal A. Bakir ◽  
Dima H. Takruri
Keyword(s):  
Body Weight ◽  
Body Fat ◽  
Date Palm ◽  
The Body ◽  
Control Group ◽  
Hormone Concentration ◽  
Palm Fruit ◽  
Menstrual Status ◽  
Feeding Duration ◽  
Effect Of Feeding

Background : Female menstrual changes in hormone concentration influence appetite and eating behavior. As well, eating pattern has some influences on menstrual hormonal status. Feeding date palm fruit has been found in our previous report to affect menstrual hormones and some menstrual parameters. Objective: The aim of this research is to study the effect of feeding dates on energy, macronutrient, and fiber intakes, body weight, and body fat%. Additionally, this study aims to find any correlation between menstrual hormone concentration and the above-mentioned parameters. Methods: A convenient sample (n=37) of not-sexually active females aged 20-30 were divided into two groups; one group (dates group) was fed 7 dates and the other served as a control group. The participants of the control group were exposed to the same experimental conditions except for eating dates. Throughout the feeding trial, the volunteers filled a 3-day food record; one menses day and two non-menses days. Results: There was a significant effect of the menstrual status-feeding duration interaction in terms of protein and fat intakes. Additionally, menstrual status, as well as feeding duration, affected energy and macronutrient intakes significantly. Furthermore, feeding duration affected fiber intake significantly. Despite the above-mentioned differences in energy and macronutrient intakes, these effects didn’t affect the body weight and body mass index of the study participants, neither their body fat%. Moreover, we have found significant correlations between nutrient intakes and menstrual hormone concentration. Conclusion : Feeding dates affected energy, macronutrient, and fiber intakes significantly. These effects were related to the changes in menstrual hormone concentration.

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