The Role of Type D Personality in Acute Coronary Syndrome

Introduction: Acute Coronary Syndrome (ACS) is one of the most common causes of death in patients with Cardiovascular Diseases (CVD). In addition to the known physical factors influencing the incidence of CVD, some psychologists have pointed to the role of psychological factors such as personality type. Objective: This study aimed to determine the role of type D personality in ACS patients in Iran in 2019. Materials and Methods: In a case-control study, 112 participants were included. A total of 56 patients with ACS were compared with 56 matched people without ACS. They were selected by the convenience sampling method. Type D scale 14 (DS14) was used to assess the type D personality. The Chi-squared test, independent t-test, and multivariate logistic regression were used to analyze the obtained data. Results: The Mean±SD age in the case group was 57.23±8.562 years, and in the Mean±SD age in the control group was 57.25±8.529 years. Also, most participants in both groups were men (71.4%). The result showed that type D personality was more prevalent in patients with ACS (26% vs 7.1%; P=0.006). Based on multivariate regression analysis and after controlling for demographic and clinical risk factors, type D personality was independently associated with ACS (OR=5.323, 95% CI; 0.987-28/712, P=0.052). Also, after investigating subscales, only social inhibition had a significant association with ACS (P=0.008). Conclusion: Type D personality is an independent risk factor of the ACS. Thus, type D personality may make people vulnerable to the ACS. Therefore, besides medical interventions, clinicians must consider behavioral interventions to reduce the incidence of ACS.

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A STUDY OF HYPERURICACIDEMIA AND THE PRESENCE AND SEVERITY OF ACUTE CORONARY SYNDROME IN INDEX MEDICAL COLLEGE, HOSPITAL AND RESEARCH CENTER, INDORE ( M.P.)

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v5i7.2029 ◽

2021 ◽

Vol 5 (7) ◽

Author(s):

B. Khanam ◽

M. Imran Khan ◽

Ajay Kumar Singh ◽

Sumit Solanki ◽

S.M. Holkar

Keyword(s):

Acute Coronary Syndrome ◽

Control Group ◽

Case Group ◽

College Hospital ◽

Medical College ◽

Coronary Syndrome ◽

Luminal Stenosis ◽

Angiographic Evidence ◽

The Mean ◽

High Uric Acid

Background: Few studies have assessed the relation of hyperuricacidemia with the acute coronary syndrome (ACS). This study investigated the association between high uric acid levels with the presence and severity of ACS. Methods: Three hundred and seventy patients having angiographic evidence of atherosclerosis (CAD + case group) compared to 170 patients with no luminal stenosis (n=110) or with <50% luminal stenosis (n=60) at coronary angiography (CAD – control group). Results: The mean age of the patients was 60 ± 10 years (317 men, 58.7%). Hyperuricacidemia was more likely associated with a trend toward higher vessel scores, indicating a more severe CAD (adjusted OR=1.51, 95% CI=1.09-2.09; P=0.005) in the whole population. A comparison of sex-specific values showed a significant association existed only in men. Conclusions: Asymptomatic hyperuricacidemia may be associated with the presence and severity of ACS. Keywords: Hyperuricacidemia, Severity & Acute Coronary Syndrome.

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Efficacy of Hematological and Coagulation Parameters in the Diagnosis and Prognosis of Patients with Acute Coronary Syndrome

The Journal of Tehran University Heart Center ◽

10.18502/jthc.v13i3.131 ◽

2018 ◽

Author(s):

Arsalan Majeed Adam ◽

Muhammad Armughan Ali ◽

Arshad Ali Shah ◽

Ather Hasan Rizvi ◽

Aiman Rehan ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Blood Cell ◽

Cox Regression ◽

Control Group ◽

Case Group ◽

Coagulation Parameters ◽

Coronary Syndrome ◽

Diagnosis And Prognosis ◽

Wbc Count

Background: The diagnosis and management of acute coronary syndrome (ACS) have improved significantly over the past few decades; however, the recognition of myocardial ischemia still proves to be a dilemma for cardiologists. The aim of this study was to determine the role of hematological and coagulation parameters in the diagnosis and prognosis of patients with ACS. Methods: This prospective study recruited 250 patients with ACS and 250 healthy controls. The diagnostic role of hematological and coagulation parameters was assessed by comparing the patients with ACS with the control group. The relationships between these parameters and mortality were determined by dividing the patients into 2 groups: Group A (discharged) and Group B (patients who died within 30 days of follow-up). Multivariate Cox regression analysis was performed to calculate the hazard ratio (HR). Results: The mean age of the patients was 55.14±10.71 years, and 65.2% of them were male. Prothrombin time (P<0.001), activated partial thromboplastin time (P<0.001), mean platelet volume (MPV) (P<0.001), white blood cell (WBC) count (P<0.001), and red blood cell distribution width (RDW) (P<0.001) were significantly higher in the case group than in the control group. WBC count (P<0.001), RDW (P<0.001), and MPV (P<0.001) were significantly higher in the controls than in the case group. The Cox regression model showed that RDW above 16.55% (HR=6.8), MPV greater than 11.25 fL (HR=2.6), and WBC higher than 10.55×103/μL (HR=6.3) were the independent predictors of mortality. Conclusion: In addition to being the independent predictors of short-term mortality, RDW, WBC, and MPV when used together with the coagulation profile may aid in the diagnosis of ACS in patients presenting with chest pain.

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Association Between Intraventricular Conduction Disorders and Intrahospital Prognosis in Patients with Acute Coronary Syndrome

Internal Medicine And Medical Investigation Journal ◽

10.24200/imminv.v2i4.88 ◽

2018 ◽

Vol 3 (1) ◽

pp. 32

Author(s):

Mehdi Latif ◽

Mohammad Salehi ◽

Nazanin Janfada ◽

Leila Foroutan ◽

MohammadMoein Ashrafi

Keyword(s):

Risk Factors ◽

Acute Coronary Syndrome ◽

Ejection Fraction ◽

Significant Relationship ◽

Control Group ◽

Case Group ◽

Intraventricular Conduction ◽

Coronary Syndrome ◽

Conduction Disorders ◽

The Mean

Background: Acute coronary syndrome (ACS) is one of the most common heart diseases. Interventricular conduction disorders are complications of acute myocardial infarctions and have different types, such as left and right bundle branch blocks and left anterior and posterior hemiblocks. The prognosis of this disease can affect therapeutic methods, duration of hospitalization, and timely intervention decisions. Therefore, in this study, we evaluated the relationship between interventricular conduction disorders and the prognosis of patients with ACS.Methods: Using the convenience sampling method, this analytical case-control study was conducted on 140 patients with ACS (61 patients in the case group and 79 patients in the control group) who were treated from March to August 2013. The underlying variables of the risk factors for ACS were evaluated, along with prognostic evaluation factors, in two groups: a case group (patients with interventricular conduction disorders) and a control group (patients without interventricular conduction disorders). Data were analyzed with SPSS v. 17 software using the chi-squared test, the analysis of variance test, Student’s t-test, and Fisher’s exact test. Results: The mean age of patients was 64.1 ± 5.8 years in the case group and 62.9 ± 8.8 years in the control group. No significant relationship was observed between ACS risk factors, such as hyperlipidemia, diabetes, hypertension, previous myocardial infarction, and smoking, and the prognosis of patients with ACS. The mean ejection fraction was 39.7 in the case group and 45.1 in the control group, so a significant relationship existed between the two groups (P<0.05). In addition, systolic heart failure was more common in the case group than in the control group.Conclusion: We found that the presence of auscultation (rales sound) and shortness of breath on the first day of hospital admission in the case group was significantly different from the control group (P<0.05). Furthermore, the ejection fraction in the case group was lower than in the control group, and the frequency of mitral regurgitation in the case group was higher than in the control group. These factors can effectively predict the prognosis of patients with ACS. Finally, we found that interventricular conduction disorders weakened the prognosis of patients with ACS.

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Early Neuromuscular Blockade in Children with Pediatric Acute Respiratory Distress Syndrome

Journal of Pediatric Intensive Care ◽

10.1055/s-0040-1708557 ◽

2020 ◽

Vol 09 (03) ◽

pp. 201-206

Author(s):

Surabhi Chandra ◽

Sahil Goel ◽

Ritika Dawra

Keyword(s):

Mechanical Ventilation ◽

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Neuromuscular Blockade ◽

Distress Syndrome ◽

Control Group ◽

Case Group ◽

The Mean ◽

Mean Time

AbstractPediatric acute respiratory distress syndrome (PARDS) is a challenging problem with high mortality. Role of neuromuscular blockade in the management of ARDS to date has been controversial, and this study was done to study the role of neuromuscular blockade in children having PARDS and development of associated complications, if any. This was a prospective, case–control study conducted in the pediatric intensive care unit (PICU) of a tertiary care teaching hospital, over a period of 24 months. Patients of age 1 to 18 years who presented with or developed PARDS during their course of hospitalization were included after written informed consent was obtained from their parents and/or guardians. Patients with PARDS requiring invasive mechanical ventilation were partitioned into a case group and a control group. Case group patients were sedated and paralyzed using midazolam (1 µg/kg/min) and vecuronium (1 µg/kg/min), respectively, along with institution of definitive management. Control group patients were given definitive and supportive therapy, but no neuromuscular blocking agents (NMBAs). All patients were followed up for signs and symptoms of myopathy or neuropathy during the entire duration of hospital stay and up to 3 months after discharge. During the study period, 613 patients were admitted to the PICU of which 91 patients qualified as having PARDS. Sepsis was the main etiology in 67 of the 91 patients (73.6%) with PARDS. Fifty-nine patients were included in the study, of which 29 patients were included in the case group and 30 patients were included in the control group. Among the 29 case group patients, 25 patients (86.2%) were successfully extubated. Four patients from the case group expired, while 14 out of 30 control group patients (46.7%) expired. Hypotension was present in 26 case group patients (89.6%), of which all showed resolution within 48 hours of definitive treatment. The mean time to resolution of hypotension was 41.6 hours (standard deviation [SD]: 5.759; range: 24–48) for case group patients, significantly lower (p < 0.0001) than the mean time to resolution of 103 hours (SD: 18.995; range: 90–126) for the 10 control group patients with hypotension that survived. Mean oxygenation index (OI) following 48 hours of vecuronium therapy was significantly lower (p < 0.0001; 95% confidence interval: 5.9129–9.9671) than mean OI at admission for case group patients. None of the patients receiving vecuronium exhibited neuromuscular deficit during their hospital stay, at time of discharge, or at follow-up evaluation up to 3 months after discharge. In this study, pediatric cases diagnosed with PARDS and managed with mechanical ventilation and vecuronium therapy had improved mean OI following 48 hours of NMBA therapy and a lower mortality when compared with matched control group patients. Incidence of NMBA-related weakness was not commonly observed in these patients.

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Type D Personality in Never Depressed Patients at Their First Acute Coronary Syndrome

Psychotherapy and Psychosomatics ◽

10.1159/000358525 ◽

2014 ◽

Vol 83 (3) ◽

pp. 190-191 ◽

Cited By ~ 2

Author(s):

Carlo Marchesi ◽

Paolo Ossola ◽

Francesca Scagnelli ◽

Francesca Paglia ◽

Sonja Aprile ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Type D Personality ◽

Coronary Syndrome ◽

Depressed Patients ◽

Type D

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Role of Segmental and Global Left Ventricular Strain in Diagnosis of Acute Coronary Syndrome

Kardiologiia ◽

10.18087/cardio.2020.5.n860 ◽

2020 ◽

Vol 60 (5) ◽

pp. 20-24

Author(s):

A. L. Chilingaryan ◽

L. G. Tunyan ◽

R. V. Shamoyan

Keyword(s):

Acute Coronary Syndrome ◽

Coronary Artery ◽

Sensitivity And Specificity ◽

False Negative ◽

Left Ventricular ◽

Middle Part ◽

Control Group ◽

Acute Ischemia ◽

Coronary Syndrome

Aim To determine the role of left ventricular segmental (SLS) and general longitudinal strain (GLS) in early diagnosis of acute coronary syndrome (ACS).Material and methods The study included 112 patients aged 58±7 years with suspected ACS without a history of ischemic heart disease (IHD) who were admitted to the hospital within 12 h of complaint onset. The control group consisted of 20 healthy, age- and sex-matched subjects. Speckle-tracking echocardiography was performed to assess SLS and GLS on admission and discharge. Ischemia was diagnosed when the SLS was decreased to 14% or lower with a simultaneous post-systolic shortening (PSS) of these segments >20% or when the initial lengthening of the segments was followed by PSS.Results Decreased SLS with PSS of one or more segments was observed in 51.8 % of patients; 16.1% of patients had initial systolic lengthening of one or more segments followed by PSS. In 30.3 % of patients, GLS was 15.5 % or less; 82.3% of these patients had SLS disorders. Later, ACS was diagnosed in 72.3 % of the patients. ACS was not confirmed in 4 (5.2%) of 76 (67.9 %) patients with abnormal SLS changes. All these patients had low SLS values and high PSS values and did not have the initial systolic segmental lengthening. Seven of 9 (8 %) patients with false-negative SLS values had distal narrowing of a coronary artery and two patients had narrowing in the middle part of the artery. All patients with ACS and decreased GSL had a hemodynamically significant narrowing of more than one coronary artery. Incidence of two and more stenosed arteries was higher in patients with PSS and low GSL. Sensitivity and specificity of SLS for diagnosis of acute ischemia were 88.9 and 84.6 %, respectively.Conclusion Assessment of LV strain has high sensitivity and specificity for diagnosis of ACS in patients with the first IHD episode. The presence of PSS associated with decreased GSL may indicate multivascular IHD.

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P.2.g.003 Type D personality and depression in Portuguese patients with acute coronary syndrome: identifying high risk groups

European Neuropsychopharmacology ◽

10.1016/s0924-977x(08)70535-2 ◽

2008 ◽

Vol 18 ◽

pp. S374-S375

Author(s):

J. Prata ◽

S. Ramos ◽

R. Coelho

Keyword(s):

Acute Coronary Syndrome ◽

High Risk ◽

Risk Groups ◽

Type D Personality ◽

Coronary Syndrome ◽

Type D

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Association of Serum Ferritin Level with Acute Coronary Syndrome

Bangladesh Heart Journal ◽

10.3329/bhj.v32i2.36094 ◽

2018 ◽

Vol 32 (2) ◽

pp. 89-93

Author(s):

Abu Thaher Mohammad Mahfuzul Hoque ◽

HI Lutfur Rahman Khan ◽

Abdul Wadud Chowdhury ◽

Md Mohshin Ahmed ◽

Khandker Md Nurus Sabah ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Serum Ferritin ◽

Serum Ferritin Level ◽

Ferritin Level ◽

Control Group ◽

Case Group ◽

Newly Diagnosed ◽

College Hospital ◽

Medical College ◽

Coronary Syndrome

Background: A substantial number of patients get admitted in different hospitals of Bangladesh with the diagnosis of acute coronary syndrome (ACS). No underlying conventional risk factors can be identified in significant number of these patients. Therefore new emerging risk factors are likely to be involved in these patients. As many authors reported that high serum ferritin levels are associated with diabetes mellitus (DM) and hypertension (HTN), it may have role in the pathogenesis of ACS.So we designed this study to test the relation between hyperferritinemia and newly diagnosed acute coronary syndrome patients of Bangladesh.Methods: The study was an observational case control study done in Department of Cardiology, Dhaka Medical College Hospital, from January 2013 to December 2013. Newly diagnosed patients with acute coronary syndrome (ACS) in the age group of 30- 70 years, admitted in the coronary care unit (CCU) of Dhaka Medical College Hospital, Dhaka, within the study period were taken as cases and age& sex matched healthy subject with no history of ischemic heart disease (IHD) and with normal ECG were taken as control by purposive sampling. In our study, the number of cases and controls were 65 each. So, total number of subject was 130.Results: According to the serum ferritin level both cases and controls were divided into two sub groups: subjects with normal ferritin level and with hyperferritinaemia. Normal ferritin level was found in 35(53.8%) subjects of case group and 62(95.4%) subjects of control groups. Hyperferritinaemia was found in 30(46.2%) subjects of case group and 3(4.6%) subjects of control group. Hyperferritinaemia was found to be significantly higher in case group than in control group (p<0.001).Conclusion: The study concludes that the serum ferritin level of patients with ACS was significantly higher than the control group.Bangladesh Heart Journal 2017; 32(2) : 89-93

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