scholarly journals PROFILE OF SINONASAL TUMOR PATIENT IN ADAM MALIK GENERAL HOSPITAL 2016-2018

2020 ◽  
Vol 3 (3) ◽  
Author(s):  
Ulfatul Ulya ◽  
Ashri Yudhistira ◽  
Andrina Y.M Rambe ◽  
Yetty Machrina

Abstract. Sinonasal tumor is a neoplasm that arises from nasal and paranasal sinus tissue. It is rarely found, only <3% of all malignancy in head and neck, and 1% of all malignancy in the body. Although it is rarely found, it can cause serious complication in adult. Unspecific sign and symptoms of sinonasal tumor often make the patients ignore the disease. It leads to the diagnosis of this disease becomes late and the patients come to the doctor in advanced stage. This research was conducted to know about the profile of sinonasal tumor patients in H. Adam Malik Medan Hospital on 2016-2018. The study was a descriptive study with retrospective approach. The data used are secondary data taken from medical records. The data were analyzed using a statistical application programs. Sinonasal tumor patients in RSUP HAM Medan are 158 patients, where 95 patients met the inclusion criteria, consisting of  24 benign tumors (25,3%) and 71 malignant tumors (74,7%). The majority of patients are male (71,6%), and the highest age group in in 51-60 years old (31,6%). The main complaints felt by the patients were nasal symptoms (64,2%), the location of tumors mostly found in nasal cavity (50,5%), the most histopathological type is NKSCC (43,2%), the most occupation is self-employment (26%), and the treatment of the patients are surgery (29,5%). Keyword: Sinonasal Tumor, Profile, Sinonasal Cancer

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Nafise Shamloo ◽  
Alireza Ghanadan ◽  
Fahimeh Sadat Hashemian ◽  
Maedeh Ghorbanpour

Background: Salivary gland tumors include a wide variety of benign and malignant tumors in the oral and maxillofacial region. Although these tumors are not common, they are not rare. The prevalence of these tumors varies with regard to age, gender, and their location in the body. Objectives: This study aimed to evaluate the frequency of benign and malignant salivary gland tumors in patients referred to three referral hospitals in Tehran, Iran. Methods: This retrospective cross-sectional study examined the demographic and pathologic records of the patients with salivary gland tumors submitted to the Department of Pathology of Amir Alam, Loghman Hakim, and Shohada Hospitals from 2005 to 2016. In this study, the histological variants of salivary gland tumors and clinical parameters such as age, gender, and the location of the tumor were examined. The clinical data were analyzed using SPSS software version 21. Results: Of 137632 patient records, 1180 cases were salivary gland tumors. Pleomorphic adenoma in 794 cases (67.3%) and adenoid cystic carcinoma in 109 cases (9.2%) were the most common tumors, respectively. Salivary gland tumors were more common in males, and the participants’ mean age was 42.86 ± 16.5 years. The most common site was parotid and minor salivary glands, with 937 (79.4%) and 137 (12%) cases, respectively. Conclusions: In this study, the most common benign tumor was pleomorphic adenoma in the parotid gland, and the most common malignant tumor was adenoid cystic carcinoma in the major salivary glands. Furthermore, benign tumors were more frequent than malignant tumors.


Author(s):  
Khadija S. Tapadar ◽  
Manoj K. Deka ◽  
R. N. Chaubey ◽  
Shah A. Sheikh ◽  
Gargi R. Choudhury ◽  
...  

Background: Soft tissue tumors are defined as mesenchymal proliferations which occur in the extraskeletal non-epithelial tissues of the body, excluding the viscera, coverings of brain and   lymphoreticular system. The objective of this study was to study the histopathological features of soft tissue tumors and to study the occurrence of soft tissue tumors in relation to age, sex and anatomical site.Methods: This study comprised of 89 cases studied over a period of two years. All soft tissue tumors, their gross features, microscopic findings were analysed in detail. Soft tissue tumors were divided into benign and malignant categories and further sub typing were done according to World Health Organization (WHO) classification. The distribution of soft tissue tumors according to the age, sex and site of occurrence was studied.Results: Out of 89 cases of soft tissue tumors, 76 cases were benign, 4 cases belonged to intermediate category and 9 cases were malignant. Adipocytic tumors formed the largest group constituting 39 cases. Vascular tumors were the second commonest (26 cases) followed by peripheral nerve sheath tumors (11 cases). The benign tumors were seen in younger age as compared to malignant tumors. Malignant soft tissue tumors was seen to be more common in male than female and pleomorphic sarcoma and liposarcoma was commonest (3 cases each).Conclusions: Benign tumors were more common than malignant. The most common benign tumors were lipoma followed by hemangioma and schwannoma. The most common malignant tumor was pleomorphic sarcoma. The benign tumors were seen in younger age as compared to malignant tumors.


2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Faseeh Khaja ◽  
Allison Carilli ◽  
Said Baidas ◽  
Aravindhan Sriharan ◽  
Shanedelle Norford

Perivascular epithelioid cell tumors are soft tissue tumors that can occur in various locations in the body whose incidence is rising. Hepatic PEComas are quite rare and diagnosis involves positivity of Melan-A and HMB45 on immunohistochemistry. Usual treatment is surgery for benign tumors and chemotherapy including mTOR inhibitors for malignant tumors. Here we discuss the radiological and pathological diagnosis, evaluation, and management of a hepatic PEComa. We describe a 51-year-old patient who was diagnosed incidentally after unusual physical exam findings.


10.12737/3326 ◽  
2014 ◽  
Vol 21 (1) ◽  
pp. 115-121 ◽  
Author(s):  
Сулейманова ◽  
N. Suleymanova

The scientific review discusses the correlation between the MN morbidity rate of the female genitalia and the factors of the external and internal environment of the body: genetic (hereditary) and environmental (exogenous and endogenous). The author notes that the significance of the factors in the development of oncological process is different depending on the form and localizations of malignant tumors. Identified genes are responsible for the appearance of hereditary ovarian cancer (however, the genes of predisposition to cancer of body and cervix of the uterus don’t identified so far). The role of human papillomavirus infection (in the genesis of pre-cancerous lesions and cervical cancer) in hormone homeostasis due to functional and anatomical changes in the hypothalamic-pituitary-ovarian system (in formation of cancer of the womb and ovaries) is proved, including the background processes and pre-cancerous changes in the occurrence of all forms of genital cancer. A number of researchers consider benign tumors as an intermediate in the pathological process changes that lead with time under the influence of certain factors to be precancerous and malignant transformation. Significant fluctuations in the frequency of malignant tumors of female genital organs in different ethnic groups of the population are scientifically confirmed. Correlation frequency of cancer of the genitalia in women with age, and state of the immune system are noted.


2021 ◽  
Vol 7 (1) ◽  
pp. 8-14
Author(s):  
Nanik Sudaryatmi ◽  
Siti Masrochah ◽  
Muhammad Erfansyah

Background: A bone scan or commonly referred to as bone print is nuclear medicine examination using a radioactive substance or radiopharmaceutical that is inserted into the body through intravenous injection which aims to help diagnose abnormalities that occur in the bone. This imaging procedure uses a radiopharmaceutical 99mTc-MDP (methylenediphosphonate) is the most commonly used radiopharmaceutical.Methods: The patient will be injected with this radiopharmaceutical at a dose of 15-20 mCi, through the vein in the hand. Imaging can be done as soon as the radiopharmaceutical is injected or after a while to wait for the radiopharmaceutical to be distributed and absorbed by the bone, about 3-5 hours later. Imaging is done by three-phase method, namely the first phase (Vascular phase), the second phase (Blood Pool phase), and the third phase (Total body phase) l.Results: The bone scan method is an efficient examination because in 1x the imaging can provide a complete picture from the head to the foot. Evaluation of results, under normal conditions the distribution of radioactivity in the bone appears symmetrical.Conclusion: In the process of bone metastasis, it can be seen that typical pathological radioactivity can be multiple (multiple hot spots). Malignant tumors can be distinguished from benign tumors by blood pool examination.


Author(s):  
Manjula S Dalabanjan ◽  
Pratibha Agrawal ◽  
Deepthi T ◽  
M. D. Suranagi

Cancer begins in cells, the building blocks that make up tissues. Tissues make up the organs of the body. The buildup of extra cells often forms a mass of tissue called a growth, polyp or tumor. Tumors can be benign (non cancerous) or malignant (cancerous). Benign tumors are not as harmful as malignant tumors. The transformation of normal cells into cancer cells is called Carcinogenesis.Cancer is one of the major health problems persisting world-wide. Urbanization, industrialization, changes in lifestyles, population growth and ageing all have contributed for epidemiological transition in the country. The absolute number of new cancer cases is increasing rapidly due to growth in size of the population The stages of cancer are considered as different states of a Markov Process. Discrete-time Markov chains have been successfully used to investigate treatment programs and health care protocols for chronic diseases like HIV, AIDS, Hypertension etc. In this study, the process of carcinogenesis was classified into 6 states. The history of every patient is recorded in the form of a data segment starting from initial state.The transitional states and absorbing states are well defined. Since all the patients under study do not reach the last state at a given point of time, the process was studied as a Semi Markov Process. Maximum likelihood estimation of the transitional probabilities, the survival function, the hazard function and the waiting time distribution of patients in different states were studied. This kind of statistical methodology used to study the prognosis of cancer can be applied to real-time data of cancer patients.


2016 ◽  
Vol 101 (5-6) ◽  
pp. 233-240 ◽  
Author(s):  
Beyhan Yılmaz ◽  
Salih Bakır ◽  
Edip Erdal Yılmaz ◽  
Engin Şengül ◽  
Ömer Uslukaya ◽  
...  

The purpose of this study was to investigate the aerodynamic and acoustic changes after thyroidectomy without laryngeal nerve injury by using objective methods. Voice samples of sustained /α/ recorded from 44 adults preoperatively and nearly 1 week and 3 months after thyroidectomy were analyzed for mean vocal fundamental frequency (Mean Fo, Hz), maximum fundamental frequency (Max Fo, Hz), minimum fundamental frequency (Min Fo, Hz), jitter, shimmer, glottal to noise excitation ratio (GNE), irregularity, noise, overall severity, S time, Z time, S/Z ratio, and maximum phonation time (MPT). Voice samples were analyzed using the lingWAVES software. The comparisons of preoperative and early and late postoperative acoustic parameters revealed significant differences in Mean F0, Max F0, MPT, and S Time between the early and late postoperative periods. The voice changes after thyroidectomy were not affected by age, sex, or surgical procedure, but they differed between the benign and malignant nature of the tumor. Patients with malignant tumors showed a greater decrease in Mean F0 and Max F0 compared with the patients with benign tumors, and this difference was statistically significant. Voice changes may occur after thyroidectomy even in the patients with no evidence of laryngeal nerve damage, and these changes can be assessed with objective measurement methods. This information should be explained to the patients during the preoperative counseling, and proper informed consent is ethically and legally required for all planned thyroidectomies.


2021 ◽  
Vol 18 ◽  
pp. 32-42
Author(s):  
Zakia Sultana ◽  
Md. Ashikur Rahman Khan ◽  
Nusrat Jahan

Breast cancer is one of the most dangerous cancer diseases for women in worldwide. A Computeraided diagnosis system is very helpful for radiologist for diagnosing micro calcification patterns earlier and faster than typical screening techniques. Maximum breast cancer cells are eventually form a lump or mass called a tumor. Moreover, some tumors are cancerous and some are not cancerous. The cancerous tumors are called malignant and non-cancerous tumors are called benign. The benign tumors are not dangerous to health. But the unchecked malignant tumors have the ability to spread in other organs of the body. For that early detection of benign and malignant tumor is important for confining the death of breast cancer. In these research study different neural networks such as, Multilayer Perceptron (MLP) Neural Network, Jordan/Elman Neural Network, Modular Neural Network (MNN), Generalized Feed-Forward Neural Network (GFFNN), Self-Organizing Feature Map (SOFM) Neural Network, Support Vector Machine (SVM) Neural Network, Probabilistic Neural Network (PNN) and Recurrent Neural Network (RNN) are used for classifying breast cancer tumor. And compare the results of these networks to find the best neural network for detecting breast cancer. The networks are tested on Wisconsin breast cancer (WBC) database. Finally, the comparing result showed that Probabilistic Neural Network shows the best detection result than other networks.


2020 ◽  
Vol 4 (2) ◽  
pp. 33-34
Author(s):  
Miyayu Soneta Sofyan ◽  
Koesnoto Supranianondo ◽  
Ira Sari Yudaniayanti ◽  
Aisyah Novasari ◽  
Endah Paraswati

The dog named Agra (Golden Retriever) is suspected of having an axillary tumor. After surgery and examination of the pathology laboratory, it was found that the dog had fibrosarcoma in the axillaries. Fibrosarcoma is a malignant neoplasm that originates from mesenchymal cells, where the dominant cell histology is fibroblast cells that divide excessively and uncontrollably, can attack local tissues, and can move to other locations in the body (metastatic). The histopathological features of fibrosarcoma have fusiform or spindle-shaped cell fascicular growth patterns. The boundary between cells appears unclear with little cytoplasm and collagen fibers form parallel webbing. Grading histology is mainly based on the degree of cellularity, cell differentiation, mitotic features, and the amount of collagen produced by the cell necrosis. Surgery until now is the first and foremost thing in tumor therapy. Benign tumors can be removed with various surgical techniques depending on the location of the tumor. As for malignant tumors, surgery can be carried out by following other additional therapies to inhibit tumor growth.


2021 ◽  
Vol 9 (4) ◽  
pp. 49-53
Author(s):  
A Sangamithra ◽  
S Vishnu

According to the World Health Organization (WHO), each year universally, about 14 million people have realized that they have cancer and eight million individuals die from cancer. Cancer is a term for a group of diseases that can affect any part of the human body. Some more terms used are malignant tumors and neoplasms. Defining cancer is the quick creation of abnormal body cells that develop outside their usual borders and occupy adjoining parts of the body and extent to another organ of the body. The study aims to assess the cost incurred for Treatment among cancer patients in Coimbatore. The research source is from both primary and secondary data. The primary data was collected from two hospitals in Coimbatore through constructed exit interview schedule and secondary sources from from other various journals and articles.


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