scholarly journals Prevalence of tumor pathology of dogs in the metropolis

2021 ◽  
Vol 9 (2) ◽  
pp. 98-104
Author(s):  
G. V. Samoilіuk
Keyword(s):  
Bone Neoplasms ◽  
Soft Tissue Sarcomas ◽  
Skin Neoplasms ◽  
Benign Tumors ◽  
Malignant Neoplasms ◽  
Tumor Pathology ◽  
Hind Limbs ◽  
Oncological Diseases ◽  
Myxoid Liposarcomas ◽  
The City

A statistical analysis of the prevalence of tumor pathology of dogs in the city of Dnipro. 418 cases of registered oncological diseases of dogs were analyzed. It was found that malignant neoplasms are 1.5 times more common than benign. The most common tumors in dogs are tumors of the breast (35,9%), skin (22,0%), genitals (15,3%) and lymphoma(8,4%). Malignant neoplasms of the breast are registered 3.6 times more often than benign and surpass them in morphological varieties. Fibroadenomas and infiltrating and non-infiltrating carcinomas were mainly registered. Approximately the same number of cases of infiltrating and non-infiltrating cancers were noted. Benign skin tumors are more common than malignant. Mastocytosis, melanoma, and squamous and basal cell carcinomas of the skin and sebaceomas were the most commonly reported. In terms of morphological varieties, benign skin neoplasms are superior to malignant ones. Lipomas and papillomas are very common. Genital neoplasms of females and males are also common. Almost half of male genital tumors were malignant seminomas. Among benign neoplasms, serteliomas and leydigomas were more common. In females, the most common are uterine leiomyoma, vaginal fibroma and ovarian carcinoma. Lymphomas (8.4%) are also widespread in dogs in the metropolis. The average age of registration of these neoplasms was 7.5 years. Benign tumors in the oral cavity of dogs were twice as common as malignant, of which fibrosarcomas, squamous keratinized and non-keratinized carcinomas, and salivary gland adenocarcinomas were reported. In females, oral neoplasia occurred 3.2 times more often than in males. Only malignant venereal sarcomas and carcinomas were found in the nasal cavity of dogs. Sexual and pedigree predisposition was not observed here. Among neoplasms of muscles and bones there was only a malignant oncological pathology. Rhabdomyosarcomas, fibrosarcomas, myxoid liposarcomas and other soft tissue sarcomas were diagnosed in different parts of the dog’s body. Bone neoplasms are represented by osteosarcomas. Dogs of large breeds were most often affected and in most cases the hind limbs were affected. The predominant histological subtype was osteoblastic osteosarcoma.

scholarly journals Digital Lesions in Dogs: A Statistical Breed Analysis of 2912 Cases

2021 ◽  
Vol 8 (7) ◽  
pp. 136
Author(s):  
Julia Maria Grassinger ◽  
Andreas Floren ◽  
Tobias Müller ◽  
Argiñe Cerezo-Echevarria ◽  
Christoph Beitzinger ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Soft Tissue Sarcomas ◽  
Benign Tumors ◽  
Malignant Neoplasms ◽  
Routine Diagnostics ◽  
Mast Cell Tumors ◽  
Neoplastic Processes ◽  
Study Population ◽  
Tumor Like Lesions ◽  
Labrador Retrievers

Breed predispositions to canine digital neoplasms are well known. However, there is currently no statistical analysis identifying the least affected breeds. To this end, 2912 canine amputated digits submitted from 2014–2019 to the Laboklin GmbH & Co. KG for routine diagnostics were statistically analyzed. The study population consisted of 155 different breeds (most common: 634 Mongrels, 411 Schnauzers, 197 Labrador Retrievers, 93 Golden Retrievers). Non-neoplastic processes were present in 1246 (43%), tumor-like lesions in 138 (5%), and neoplasms in 1528 cases (52%). Benign tumors (n = 335) were characterized by 217 subungual keratoacanthomas, 36 histiocytomas, 35 plasmacytomas, 16 papillomas, 12 melanocytomas, 9 sebaceous gland tumors, 6 lipomas, and 4 bone tumors. Malignant neoplasms (n = 1193) included 758 squamous cell carcinomas (SCC), 196 malignant melanomas (MM), 76 soft tissue sarcomas, 52 mast cell tumors, 37 non-specified sarcomas, 29 anaplastic neoplasms, 24 carcinomas, 20 bone tumors, and 1 histiocytic sarcoma. Predisposed breeds for SCC included the Schnauzer (log OR = 2.61), Briard (log OR = 1.78), Rottweiler (log OR = 1.54), Poodle (log OR = 1.40), and Dachshund (log OR = 1.30). Jack Russell Terriers (log OR = −2.95) were significantly less affected by SCC than Mongrels. Acral MM were significantly more frequent in Rottweilers (log OR = 1.88) and Labrador Retrievers (log OR = 1.09). In contrast, Dachshunds (log OR = −2.17), Jack Russell Terriers (log OR = −1.88), and Rhodesian Ridgebacks (log OR = −1.88) were rarely affected. This contrasted with the well-known predisposition of Dachshunds and Rhodesian Ridgebacks to oral and cutaneous melanocytic neoplasms. Further studies are needed to explain the underlying reasons for breed predisposition or “resistance” to the development of specific acral tumors and/or other sites.

scholarly journals Spontaneous Tumors and Non-Neoplastic Proliferative Lesions in Pet Degus (Octodon degus)

2020 ◽  
Vol 7 (1) ◽  
pp. 32
Author(s):  
Tanja Švara ◽  
Mitja Gombač ◽  
Alessandro Poli ◽  
Jožko Račnik ◽  
Marko Zadravec
Keyword(s):  
Malignant Tumors ◽  
Single Case ◽  
Case Reports ◽  
Hepatocellular Adenoma ◽  
Benign Tumors ◽  
Malignant Neoplasms ◽  
Octodon Degus ◽  
Hind Limbs ◽  
Neoplastic Lesion ◽  
Veterinary Faculty

In recent years, degus (Octodon degus), rodents native to South America, have been becoming increasingly popular as pet animals. Data about neoplastic diseases in this species are still sparse and mainly limited to single-case reports. The aim of this study was to present neoplastic and non-neoplastic proliferative changes in 16/100 pet degus examined at the Veterinary Faculty University of Ljubljana from 2010 to 2015 and to describe the clinic-pathological features of these lesions. Twenty different lesions of the integumentary, musculoskeletal, genitourinary and gastrointestinal systems were diagnosed: amongst these were 13 malignant tumors, six benign tumors, and one non-neoplastic lesion. Cutaneous fibrosarcoma was the most common tumor (7/16 degus). It was detected more often in females (6/7 degus) and lesions were located mainly in hind limbs. The gastrointestinal tract was frequently affected, namely with two malignant neoplasms - an intestinal lymphoma and a mesenteric mesothelioma, four benign tumors – two biliary cystadenomas, an oral squamous papilloma and a hepatocellular adenoma, and a single non-neoplastic proliferative lesion. In one animal, two organic systems were involved in neoplastic lesions.

Temporal bone neoplasms: a report on 20 surgically treated cases

1992 ◽  
Vol 76 (4) ◽  
pp. 578-587 ◽  
Author(s):  
Laligam N. Sekhar ◽  
Shlomo Pomeranz ◽  
Ivo P. Janecka ◽  
Barry Hirsch ◽  
Sai Ramasastry
Keyword(s):  
Cranial Nerves ◽  
Bone Neoplasms ◽  
Petrous Bone ◽  
Benign Tumors ◽  
Tumor Spread ◽  
Lower Cranial Nerve ◽  
Content Type ◽  
Fast Growing ◽  
Tumor Pathology ◽  
Fine Print

✓ The surgical resection of neoplasms involving the petrous bone and surrounding areas in 20 patients is reported. Technical advances described include the total resection of several tumors previously considered inoperable due to involvement of dura and brain, petrous internal carotid artery (ICA), the vein of Labbé, and adjacent areas such as the clivus and the cavernous sinus. Areas of reconstruction after resection included the ICA, the seventh and 11th cranial nerves, and the cranial base, often requiring the use of vascularized flaps. There were no intraoperative deaths. Many patients experienced significant temporary morbidity related primarily to wound healing and to lower cranial nerve palsy; however, all but three patients (all with fast-growing malignancies) returned to their preoperative functional status. During a median follow-up period of 30 months (range 17 to 63 months), the 10 patients with benign tumors and slow-growing malignancies fared well, seven being alive and disease-free. The 10 patients with fast-growing malignancies fared poorly, only two being alive without disease. This outcome appeared to be related to tumor pathology and extent of invasion; both survivors harbored tumors confined to the petrous bone. An anatomical classification system of tumor spread is introduced, which should be considered concomitantly with tumor pathology.

scholarly journals Parapharyngeal space tumors: considerations in 26 cases

1999 ◽  
Vol 117 (1) ◽  
pp. 34-37 ◽  
Author(s):  
Alfio José Tincani ◽  
Antonio Santos Martins ◽  
Albina Altemani ◽  
Rui Carlos Scanavini Jr. ◽  
Gilson Barreto ◽  
...  
Keyword(s):  
Parapharyngeal Space ◽  
Malignant Tumors ◽  
Soft Tissue Sarcomas ◽  
Needle Aspiration ◽  
High Rate ◽  
Benign Tumors ◽  
Malignant Neoplasms ◽  
Surgical Morbidity ◽  
Neurogenic Tumors ◽  
Parapharyngeal Space Tumors

CONTEXT: Parapharyngeal space tumors comprise less than 0.5% of all head and neck neoplasms.1 The majority of these tumors are benign, but surgery is usually required to establish the diagnosis and treat the patients. We present 26 patients treated surgically for tumors arising in the parapharyngeal space (PPS) at the State University of Campinas Hospital – UNICAMP. CASES SERIE: Of these, 17 (65.5%) had benign and 9 (34.6%) malignant neoplasms. The surgical and pathological data relevant to these cases are highlighted, observing any local recurrence, surgical complications and the five-year survival. Neurogenic tumors and soft tissue sarcomas were, respectively, the most frequent benign (35.3%) and malignant neoplasms (44.5%). Benign tumors accounted for the majority of the cases and involved minimal surgical morbidity with no recurrence during a median follow-up of five years. Malignant tumors had a high rate of recurrence and mortality. Surgery is the treatment of choice for PPS tumors. A knowledge of the anatomy of this site is essential for the safe performance of surgical procedures. Malignant neoplasms have a poor prognosis. Fine needle aspiration was helpful in diagnosis of all tumors.

scholarly journals Environmentally-induced alternative oncogenesis: EROS arrows

2020 ◽  
Vol 169 ◽  
pp. 04006
Author(s):  
Sergey K. Pinaev ◽  
Olga G. Pinaeva ◽  
Alexey Ya. Chizhov
Keyword(s):  
Environmental Factors ◽  
Axon Growth ◽  
Fetal Hemoglobin ◽  
Neural Tissue ◽  
Benign Tumors ◽  
Malignant Neoplasms ◽  
Hematopoietic Stem ◽  
Oncological Diseases ◽  
Similarities And Differences ◽  
Epigenomic Regulation

The cause of the oncological diseases in children and the specific spectrum of this pathology, with hemangiomas prevailing among benign tumors (BT), and leukemia, lymphomas, and neural tissue tumors among malignant neoplasms (MN), remains unknown. The authors studied the similarities and differences of the connections between environmental factors, benign tumors and MN, as well as the relations between BT and MN. The causality of the so-called “sporadic” fluctuations in the incidence of neoplasms and their relations with environmental factors were revealed. A hypothesis of environmentally-induced alternative oncogenesis is suggested. According to the hypothesis, fetal hemoglobin enhances environmentally-related oxidative stress (EROS), leading to epigenomic regulation disorder of SEMA 7A and MICAL family proteins in the endothelium, axon growth cone, and hematopoietic stem cells.

scholarly journals Epidemiology of Oncological Diseases in the Nizhny Novgorod Region in 2017–2019

2021 ◽  
pp. 417-425
Author(s):  
Sergey A. Saburtsev ◽  
◽  
Pavel G. Chemodanov
Keyword(s):  
Absolute Number ◽  
Biological Research ◽  
Steady Increase ◽  
Malignant Neoplasms ◽  
Positive Trend ◽  
Malignant Tumours ◽  
High Prevalence ◽  
Oncological Diseases ◽  
The City ◽  
Nizhny Novgorod Region

As we know, neoplasms are characterized by high prevalence. The purpose of this study was to analyse the dynamics of cancers in the Nizhny Novgorod Region in 2017–2019. Materials and methods. The object of this research were the residents of the city of Nizhny Novgorod and the Nizhny Novgorod Region who sought medical help at Polyclinic No. 3 of the Volga District Medical Centre, Russia’s Federal Medical-Biological Agency (Nizhny Novgorod). Computed tomography was used to diagnose neoplasms. Results. In 2017, 50,470 diseases were identified, of which 2548 were neoplasms (599 malignant, and the rest benign). In 2018, 57,012 diseases were diagnosed, of which 2710 neoplasms, 639 being malignant. In 2019, the statistics was rather similar: a total of 55,110 diseases, of which 2705 neoplasms (661 malignant). Thus, the total number of diagnosed diseases, neoplasms included, was somewhat less in 2017, which can be explained by certain improvement in diagnostics and reporting, as well as a more active participation of the population in screening in 2018–2019. The absolute number of malignant neoplasms, although not much, still grows annually, and they are typically diagnosed after the age of 55–60 years. In general, the most often attacked is the digestive system, which is indicated by a steady increase in the number of new diagnoses by 1.5–2 % each year. Fortunately, there is also a positive trend, i.e. the number of malignant tumours of the excretory system, skin and female repr oductive system is falling. For citation: Saburtsev S.A., Chemodanov P.G. Epidemiology of Oncological Diseases in the Nizhny Novgorod Region in 2017–2019. Journal of Medical and Biological Research, 2021, vol. 9, no. 4, pp. 417–425. DOI: 10.37482/2687-1491-Z079

scholarly journals Intensity of development of somatic diseases of children's population in Kizlyar and Khasavyurt and cancer incidence

2021 ◽  
Vol 18 (4) ◽  
pp. 58-64
Author(s):  
F. I. Osmanova ◽  
I. N. Osmanov ◽  
T. F. Kosyreva
Keyword(s):  
Well Being ◽  
Preschool Age ◽  
Malignant Neoplasms ◽  
Male Population ◽  
Female Population ◽  
Number Of Patients ◽  
Permanent Occlusion ◽  
Oncological Diseases ◽  
Somatic Diseases ◽  
The City

Aim. Study of the development of somatic and oncological diseases and the state of the dentoalveolar system as an indicator of somatic health on the example of the city of Kizlyar (a city of ecological trouble) and the city of Khasavyurt (ecological well-being).Materials and methods. To determine the health status of children and their mothers, a survey was conducted of 1015 children and (or) their parents (three age groups of the study), of which 528 were girls and 487 were boys, and for comparison, 542 children aged 2-17 years in the city of Khasavyurt (ecological well-being) northern zone of Dagestan. Patient selection criteria: 1) identical area of residence (Kizlyar, Khasavyurt); 2) children of preschool age from 2-6 years (1, 2, 3 health groups in the absence of somatic diseases in sub- and decompensated forms), 4 health groups with chronic somatic diseases and congenital malformations; 3) Children at the age of the period of changeable occlusion from 7 to 13 years old, 1-4 health groups; 4) Children aged 14 to 17 years of permanent occlusion, 1-4 health groups.Results. According to a study of schoolchildren aged 7 to 17 years in the city of Kizlyar, 47.1% of children with habitual mouth breathing or mixed breathing. Infantile type of swallowing in children was found in 23.8% of cases. Violation of posture in children was observed in 29% of cases, while in children from the city of Khasavyurt, this type of violation was observed only in 10.5% of cases. The main localizations of malignant neoplasms in the male population are the respiratory organs, stomach, skin, bladder, lip; in the structure of oncological morbidity in the female population, the largest number of patients with neoplasms of the mammary gland, skin, lymphatic and hematopoietic tissue, cervix, and stomach.In the population (period of permanent occlusion), there was a significant decrease in tumors from 0.8% to 0.4% out of 1000 examined, the endocrine system from 0.5% to 0.4%, blood diseases from 0.2% to 0.1%.Conclusions. The results obtained confirm the presence and development of somatic and oncological diseases from unfavorable factors in the region of residence. All indicators for the city of Khasavyurt (ecological well-being) 2 times lower than the data of the city of Kizlyar (city of ecological trouble). 

Medical Care for Children with Cancer in the Donetsk People’s Republic: Results of an Ecological Study in 2014–2017

2018 ◽  
Vol 5 (3) ◽  
pp. 145-154
Author(s):  
M. Yu. Rykov ◽  
I. N. Inozemtsev ◽  
S. A. Kolomenskaya
Keyword(s):  
Medical Care ◽  
Pediatric Patient ◽  
Ecological Study ◽  
Medical Service ◽  
Care Delivery ◽  
Benign Tumors ◽  
High Tech ◽  
Malignant Neoplasms ◽  
Children With Cancer ◽  
Patient Capacity

Background.Analysis of medical care delivery for children with cancer in armed conflict is highly important because the high-tech treatment in this context is extraordinary difficult and challenging task. Objective. Our aim was to analyze the morbidity and mortality rates in children with malignant tumors, to assess the pediatric patient capacity and medical service density in the Donetsk People’s Republic.Methods.The ecological study was conducted where the units of analysis were represented by the aggregated data of the Republican Cancer Registry on the number of primary and secondary patients with malignant and benign tumors, the deceased patients in the DNR in 2014–2017, pediatric patient capacity, and medical service density.Results.The number of pediatric patient capacity for children with cancer was 10 (0.27 per 10,000 children aged 0–17), pediatric patient capacity for children with hematological disorders — 40 (1.37 per 10,000 children aged 0–17). The treatment of children with cancer was performed by 5 healthcare providers: 1 pediatric oncologist (0.02 per 10,000 children aged 0–17), 3 hematologists (0.08 per 10,000 pediatric population aged 0–17), and 1 practitioner who did not have a specialist certificate in oncology. Morbidity rate for malignant neoplasms from 2014 to 2017 decreased by 25% (in 2014 — 9.6 per 10,000 children aged 0–17; in 2017 — 7.2). In the morbidity structure, the incidence proportion of hemoblastoses was 68.4%, brain tumors — 2.6%, other solid tumors — 29%. The death rate due to malignant neoplasms decreased by 37% (in 2014 — 2.7; in 2017 — 1.7).Conclusion.Low levels of the incidence rate and pattern of morbidity indicate defects in the identification and recording of patients. This explains the performance of the bed: low average bed occupancy per year and low turnover. For a reliable analysis of mortality statistical data is not available: in 2014–2015 only the number of in-hospital deceased patients is presented. Limited data is due to the lack of reliable patient catamnesis which is explained by the high rate of population migration. 

scholarly journals Clinical and Epidemiological Characteristics of Infections Associated with Surgery and Treatment of Oncological Diseases

2019 ◽  
Vol 9 (2) ◽  
pp. 151-156
Author(s):  
G. G. Badamshina ◽  
V. B. Ziatdinov ◽  
L. M. Fatkhutdinova ◽  
G. M. Тrukhina ◽  
B. A. Bakirov ◽  
...  
Keyword(s):  
Incidence Structure ◽  
Risk Of Infection ◽  
Managerial Decision ◽  
Efficient Tool ◽  
Epidemiological Analysis ◽  
Oncological Diseases ◽  
The Russian Federation ◽  
Epidemiological Characteristics ◽  
The City ◽  
Statistical Record

Introduction. In the Russian Federation there is a constantly updated register of infections associated with surgery and the treatment of oncological diseases reporting which is mandatory. Massive expenses and detriment to patients’ health caused by these infections prompted the authors to run a retrospective epidemiological analysis of the morbidity registered in the population of the city of Kazan during the period under review. This paper presents a study of patterns of the emergence and spread of nosocomial infections.This study aims to examine the clinical and epidemiological characteristics of infections associated with surgery and the treatment of oncological diseases registered in the population of the city of Kazan.Materials and methods. Authors analysed the Emergency Notifications for an Infectious Disease (form 058/u) as well as the data from the Rospotrebnadzor Federal Statistical Record Form №2. The paper presents the morbidity annual dynamics, structure and spatial characteristics and describes key pathogens of HAIs.Results and discussion. On the basis of the data obtained the authors give clinical and epidemiological characteristics of the annual dynamics of the morbidity characterised by recurrent rises during the year with the top incidence in the autumn. Neonatal PSI infections dominate the HAIs incidence structure (52.8%). St. aureus is the priority HAI pathogen (26.5% of cases) in the city of Kazan.Conclusion. Microbiological monitoring of emerging HAIs is an efficient tool for managerial decision making and the development of an algorithm for anti-epidemic measures in the departments and the hospital as a whole for the reduction of risk of infection.

Radiation Contribution Assessment to Development of Multiple Oncological Diseases in the Late Period of Acute Radiation Disease

2021 ◽  
Vol 66 (1) ◽  
pp. 44-48
Author(s):  
I. Galstyan ◽  
M. Konchalovsky ◽  
M. Kozlova ◽  
V. Nugis
Keyword(s):  
Radiation Effects ◽  
Acute Radiation ◽  
Malignant Neoplasms ◽  
Early Diagnostics ◽  
Adequate Treatment ◽  
Clinical Observations ◽  
Oncological Diseases ◽  
The Given

Purpose: On clinical examples to estimate a probable contribution of the postponed earlier external radiation of all body in the doses exceeding 1 Gy at development of multiple malignant neoplasms of different localization and a leukaemia. Material and methods: At 8 of 164 patients, it is long observed after the postponed acute radiation syndrome (ARS), multiple oncological diseases are revealed. Dynamics of consecutive forming of solid tumors at 2 patients and also malignant neoplasms and a myelodysplastic syndrome (MDS) with transformation in an acute leukamia at 1 patient is tracked. Observation duration – 31 years, 43 years and 32 years. Results: Availability of medical care to the patients who transferred ARS and high quality of its rendering at all stages (out-patient, stationary) allowed to reveal malignant neoplasms at early stages of development and to achieve an absolute recovery. However eventually at these patients development and other oncological diseases was observed. The given clinical observations allow to assume that at presented cases radiation acted on various stages of carcinogenesis, and its contribution to development of different oncological diseases in all patients was not identical. Conclusion: The analysis of clinical observations allows to assume that radiation contribution to genesis of various oncological diseases at the persons which underwent radiation in the doses causing development of ARS is various. Now in our country there are no approaches to quantitative assessment of a contribution of radiation effects to development of malignant neoplasms in each case. The patients who underwent acute single exposition in doses over 1 Gy have to be considered as having predisposition to development of multiple tumors in the remote terms. In this regard they for life need medical follow up for the purpose of early diagnostics and adequate treatment of the developing malignant neoplasms.

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