scholarly journals Types of outcomes in research: what is their importance?

2020 ◽  
Vol 19 (4) ◽  
pp. 267
Author(s):  
José Francisco Dos Santos ◽  
Renata Sena Dos Santos ◽  
Antônio Marcos Andrade Da Costa
Keyword(s):  
Scientific Evidence ◽  
Scientific Information ◽  
Critical Evaluation ◽  
Qualitative Evaluation ◽  
Evidence Based ◽  
Sports Science ◽  
Expert Opinions ◽  
Definition Of ◽  
Decision Making Model

Currently, in the field of sports science, we are increasingly experiencing the transition from a decision-making model based on isolated expert opinions to an evidence-based decision model. This process demands that professionals have the skills and competence to carry out a systematic critical assessment of the available scientific information, before applying an intervention. Evidence-based practice is a strategy aimed at improving the quality of care for clients or patients. This approach involves the definition of a problem, the search and critical evaluation of the available scientific evidence, the application of that evidence in clinical practice and finally the quantitative and or qualitative evaluation of the results [1]...

scholarly journals Pseudomonas aeruginosa infection in patients with cystic fibrosis: scientific evidence regarding clinical impact, diagnosis, and treatment

2013 ◽  
Vol 39 (4) ◽  
pp. 495-512 ◽  
Author(s):  
Luiz Vicente Ribeiro Ferreira da Silva Filho ◽  
Flavia de Aguiar Ferreira ◽  
Francisco Jose Caldeira Reis ◽  
Murilo Carlos Amorim de Britto ◽  
Carlos Emilio Levy ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Pseudomonas Aeruginosa ◽  
Scientific Evidence ◽  
Scientific Information ◽  
Clinical Impact ◽  
Diagnosis And Treatment ◽  
Evidence Based ◽  
Pseudomonas Aeruginosa Infection ◽  
Based Medicine

Evidence-based techniques have been increasingly used in the creation of clinical guidelines and the development of recommendations for medical practice. The use of levels of evidence allows the reader to identify the quality of scientific information that supports the recommendations made by experts. The objective of this review was to address current concepts related to the clinical impact, diagnosis, and treatment of Pseudomonas aeruginosa infections in patients with cystic fibrosis. For the preparation of this review, the authors defined a group of questions that would be answered in accordance with the principles of PICO–an acronym based on questions regarding the Patients of interest, Intervention being studied, Comparison of the intervention, and Outcome of interest. For each question, a structured review of the literature was performed using the Medline database in order to identify the studies with the methodological design most appropriate to answering the question. The questions were designed so that each of the authors could write a response. A first draft was prepared and discussed by the group. Recommendations were then made on the basis of the level of scientific evidence, in accordance with the classification system devised by the Oxford Centre for Evidence-Based Medicine, as well as the level of agreement among the members of the group.

scholarly journals The Use of Evidence-Based Acupuncture: Current Evidence

2022 ◽  
Author(s):  
Dedi Ardinata
Keyword(s):  
Clinical Evidence ◽  
Scientific Evidence ◽  
Current Evidence ◽  
Systematic Research ◽  
Evidence Based ◽  
Clinical Expertise ◽  
Quality Of Evidence ◽  
Assessment Development ◽  
Evidence Quality

Evidence-based medicine (EBM), which emphasizes that medical decisions must be based on the most recent best evidence, is gaining popularity. Individual clinical expertise is combined with the best available external clinical evidence derived from systematic research in the practice of EBM. The key and core of EBM is the hierarchical system for categorizing evidence. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system divides evidence quality into four categories: high, moderate, low, and very low. GRADE is based on the lowest quality of evidence for any of the outcomes that are critical to making a decision, reducing the risk of mislabeling the overall evidence quality, when evidence for a critical outcome is lacking. This principle is also used in acupuncture as a complementary and integrative treatment modality, but incorporating scientific evidence is more difficult due to a number of factors. The goal of this chapter is to discuss how to establish a clinical evidence system for acupuncture, with a focus on the current quality of evidence for a variety of conditions or diseases.

Evidence-Based Surgery

2017 ◽  
Author(s):  
Karl Y. Bilimoria ◽  
Benjamin S Brooke
Keyword(s):  
Scientific Evidence ◽  
Surgical Techniques ◽  
Internal Validity ◽  
Surgical Care ◽  
Evidence Based ◽  
Services Research ◽  
Surgical Decision ◽  
Evidence Based Surgery ◽  
Quality Of Research

The practice of surgery has undergone a dramatic evolution over the last century with the availability of new scientific evidence supporting different surgical techniques and management.  Evidence-based surgery is defined as the judicious and systematic application of scientific evidence to surgical decision making and the establishment of standards of surgical care. This includes efforts to appraise the strength of scientific evidence and evaluate the quality of research studies or evidence, as well as efforts to interpret and apply evidence to clinical practice. In this review, we discuss important methodology and approaches in surgical health services research to accomplish these goals and improve the quality of care in surgery. By providing this overview, we hope readers will be able to navigate the surgical literature and apply evidence-based science to their own surgical practice. This review contains 1 figure, 3 tables, and 43 references. Key words: bias, comparative effectiveness, confounding, evidence, external validity, implementation science, internal validity, pragmatic trials, quality, risk adjustment, surgery

How to Search and Critique Scientific Evidence for Decision-Making

2017 ◽  
pp. 100-123
Author(s):  
Mayuree Tangkiatkumjai ◽  
Win Winit-Watjana ◽  
Li-Chia Chen
Keyword(s):  
Alternative Medicine ◽  
Complementary And Alternative Medicine ◽  
Literature Search ◽  
Scientific Evidence ◽  
Clinical Decision ◽  
Evidence Based ◽  
Search Terms ◽  
Based Medicine ◽  
Complementary And Alternative

A clinical decision on the use of complementary and alternative medicine (CAM) should be made based on evidence-based medicine (EBM) together with practitioner's knowledge and experiences. This chapter describes the process of EBM, including how to address a clinical question, do a systematic search for appropriate evidence with key search terms, appraise the evidence and make a clinical decision on CAM applications. An effective literature search should be performed by using a structured search strategy in searching biomedical and CAM databases, such as the National Center for Complementary and Alternative Medicine (CAM Citation Index). Few standard tools are recommended to evaluate the quality of CAM studies, i.e. the CONSORT extension for herbal interventions and STRICTA for RCTs of acupuncture. Additionally, some guidelines for designing RCTs in Chinese herbal medicine (CHM) can also be adopted to critique CAM literature. A clinical decision on choosing optimal CAM for patient care should be based on the current best evidence emerged from the EBM process.

Improving quality of cancer care by rapid adoption of new scientific evidence.

2013 ◽  
Vol 31 (31_suppl) ◽  
pp. 62-62
Author(s):  
Joanne Schottinger ◽  
Violeta Rabrenovich ◽  
David Campen ◽  
Dean Fredriks
Keyword(s):  
Cancer Care ◽  
Scientific Evidence ◽  
Care Program ◽  
Evidence Based ◽  
Clinical Expertise ◽  
Patient Centered ◽  
Chemotherapy Administration ◽  
Inpatient Settings ◽  
New Evidence

62 Background: The goal of the Kaiser Permanente (KP) Cancer Care Program is to provide patient-centered, evidence-based, safe care for all KP oncology patients. Multiple processes and information technology tools support KP’s clinicians in delivering the best care to our patients. Prior to 2008, chemotherapy ordering and administration across KP was paper-based, and the standardization of chemotherapy regimens was driven by prescribers’ preferences. KP Oncologists used more than 1,400 chemotherapy protocols. Pharmacy had varying systems for dosing alerts, and reliable chemotherapy administration data was not available for clinical quality improvement. Methods: By 2012, all KP regions had implemented the KP HealthConnect Beacon (KPHCB) system, which incorporates chemotherapy ordering, alerting, verifying, dispensing, and administration in ambulatory and inpatient settings. Important outcomes of the KPHCB implementation include: 1) our success in gaining agreements on standardization of chemotherapy protocols across the Program, and 2) implementation of a rapid process for adoption of new scientific evidence. Our approach includes an evaluation of the quality of the relevant scientific literature and an assessment of a particular treatment. The KP multidisciplinary team discusses and integrates the scientific evidence and clinical expertise of KP clinicians into KPHCB chemotherapy protocols. The new evidence-based protocols with supporting literature references are imbedded as a web link at the end of the each protocol and are available to clinicians within days following the publishing of new evidence. Results: An example of a rapid dissemination and adoption of evidence is the 2010 Pfizer’s and FDA’s announcement that the sale of Mylotarg would be voluntarily discontinued due to a fatal liver veno-occlusive disease. Within 48 hours, we identified 12 patients who received Mylotarg in 2010, and the treating oncologists were individually contacted and provided with the new information to discuss with patients, as appropriate. Conclusions: The benefits of KP’s rapid adoption of new evidence methodology are reaching over 40,000 cancer patients, receiving over 250,000 chemotherapy treatments annually.

Evidence-Based Surgery

2017 ◽  
Author(s):  
Karl Y. Bilimoria ◽  
Benjamin S Brooke
Keyword(s):  
Scientific Evidence ◽  
Surgical Techniques ◽  
Internal Validity ◽  
Surgical Care ◽  
Evidence Based ◽  
Services Research ◽  
Surgical Decision ◽  
Evidence Based Surgery ◽  
Quality Of Research

The practice of surgery has undergone a dramatic evolution over the last century with the availability of new scientific evidence supporting different surgical techniques and management.  Evidence-based surgery is defined as the judicious and systematic application of scientific evidence to surgical decision making and the establishment of standards of surgical care. This includes efforts to appraise the strength of scientific evidence and evaluate the quality of research studies or evidence, as well as efforts to interpret and apply evidence to clinical practice. In this review, we discuss important methodology and approaches in surgical health services research to accomplish these goals and improve the quality of care in surgery. By providing this overview, we hope readers will be able to navigate the surgical literature and apply evidence-based science to their own surgical practice. This review contains 1 figure, 3 tables, and 43 references. Key words: bias, comparative effectiveness, confounding, evidence, external validity, implementation science, internal validity, pragmatic trials, quality, risk adjustment, surgery

CFC Regulations on Refrigeration Compressors Used in Environmental Test Chambers

1990 ◽  
Vol 33 (6) ◽  
pp. 27-32
Author(s):  
Brian Hearn
Keyword(s):  
Human Life ◽  
Scientific Evidence ◽  
Scientific Information ◽  
Montreal Protocol ◽  
Environmental Test ◽  
Clean Air ◽  
Antarctic Ozone ◽  
The Antarctic

The earlier discovery of the Antarctic ozone "hole" and current scientific evidence indicate that CFC emissions into the atmosphere deplete the ozone layer and present a long-term threat to the quality of human life. The items of most concern, from an ozone protection standpoint, are the long-lived, fully halogenated compounds—halons, CFCs, and chlorocarbons. Scientific information indicates that most, if not all, of the chlorine or bromine content of these compounds is transported to the stratosphere, where it has the potential to destroy ozone. Furthermore, these compounds remain in the atmosphere for an extended number of years, providing a significant background chlorine concentration. According to DuPont.2 an 85 percent reduction in global CFC emissions from 1986 levels is necessary just to maintain current atmospheric levels of chlorine from these compounds. The refrigerants used within environmental test chambers have been included among those identified as ozone depleting. Specifically, these are CFC-12 and CFC-502. The 1987 Montreal Protocol was revised in June of 1990. Further regulations on CFC products are contained within the Clean Air Bill that is being debated in the Fall of 1990. Restrictions pertaining to CFC-13 are being proposed.

Epidemiology 2: Study Design

2010 ◽  
pp. 47-58
Author(s):  
Muktar H. Aliyu
Keyword(s):  
Study Design ◽  
Scientific Evidence ◽  
Epidemiologic Study ◽  
Scientific Research ◽  
Time Frame ◽  
Epidemiologic Studies ◽  
Evidence Based ◽  
Study Designs ◽  
Based Medicine

The usefulness of evidence arising from scientific research is influenced by several factors, and foremost among these factors is the design of the epidemiologic study from which the findings are drawn. In evidence-based medicine, the quality of scientific evidence is often graded on the base of the type of study design and includes appraisal of methods by which studies of exposure and outcomes are planned and implemented. Several factors must be considered when designing a scientific study, including the hypothesis being tested, study cost, time frame, subject characteristics, choice of variables or measurements, and ethical concerns. In this chapter, the different types of study designs commonly encountered in clinical research, common measures of morbidity and mortality in epidemiology, and errors (random and systematic) that may threaten conclusions derived from inferences arising from epidemiologic studies are discussed.

Media-Savvy Scientific Literacy: Developing Critical Evaluation Skills by Investigating Scientific Claims

2012 ◽  
Vol 74 (6) ◽  
pp. 374-379 ◽  
Author(s):  
Peggy Brickman ◽  
Cara Gormally ◽  
Greg Francom ◽  
Sarah E. Jardeleza ◽  
Virginia G.W. Schutte ◽  
...  
Keyword(s):  
General Education ◽  
Scientific Literacy ◽  
Scientific Information ◽  
Critical Evaluation ◽  
Literacy Skills ◽  
Sources Of Information ◽  
Applied Learning ◽  
Education College ◽  
Scientific Claims

Students must learn content knowledge and develop scientific literacy skills to evaluate and use scientific information in real-world situations. Recognizing the accessibility of scientific information to the average citizen, we developed an instructional approach to help students learn how to judge the quality of claims. We describe a project-based applied learning (PAL) approach that utilizes engaging questions about biological issues relevant to students. Working through these projects, students are challenged to evaluate sources of information and communicate their understanding of scientific claims. We discuss challenges that students encounter and offer suggestions for enacting this approach in a general-education college classroom.

Evidence-Based Corrections: Identifying What Works

2000 ◽  
Vol 46 (4) ◽  
pp. 457-471 ◽  
Author(s):  
Doris Layton MacKenzie
Keyword(s):  
Cognitive Skills ◽  
Scientific Evidence ◽  
Scientific Information ◽  
Evidence Based ◽  
Scientific Rigor ◽  
University Of Maryland ◽  
Assessment Technique ◽  
What Works ◽  
Step Procedure ◽  
Prevention Studies

Relatively few policy decisions regarding corrections use scientific evidence to assist in making informed decisions. This article emphasizes the importance of using evidence-based corrections if we are to be successful in reducing crime in the community. As an example of how scientific information can be used to make decisions, an assessment technique designed by University of Maryland researchers is used to assess the effectiveness of correctional strategies, interventions, and programs. This technique uses a two-step procedure for drawing conclusions about what works in crime prevention. Studies within each area (e.g., drug treatment, cognitive skills programs, educational programs) are assessed for scientific rigor. The scientific rigor score and the direction and significance of the results are used to draw conclusions about what works, what doesn't, what is promising, and what we don't know. The assessment technique is described and summaries of the findings from this assessment are presented.

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