scholarly journals Traditional Uses, Chemical Profile and Biological Activities of Piper hispidum Sw.: a Review

2021 ◽  
Vol 11 (5) ◽  
pp. 13115-13129

Piper hispidum Sw. (Piperaceae) (syn. Piper hispidinervum) is a medicinal shrub distributed in Central and South America, widely used as an astringent, diuretic, stimulant for unblocking the liver and stopping hemorrhages. The plant has great interest among researchers due to the production of essential oil and important raw material for the chemical industry, which has a high demand for cosmetic, insecticide, and pesticide industries. In this review, traditional uses, phytochemicals, and biological activities of P. hispidum are comprehensively and systematically summarized through searching scientific databases, including Science Direct, PubMed, Google Scholar, Scopus, and Web of Science. Phytochemical studies revealed the presence of amides, benzoic acids, flavonoids, phenylpropanoids, butenolides, phenol, and essential oils; hence it has several activities, such as antioxidant, antibacterial, α-amylase, insecticidal, schistosomicidal, leishmanial, larvicidal, antiplasmodial, cytotoxicity, estrogenic and serotonergic properties. This review is expected to draw the attention of medical professionals and the general public towards P. hispidum as well as to open the door for detailed research in the future.

2015 ◽  
Vol 2015 ◽  
pp. 1-30 ◽  
Author(s):  
Loh Teng Hern Tan ◽  
Learn Han Lee ◽  
Wai Fong Yin ◽  
Chim Kei Chan ◽  
Habsah Abdul Kadir ◽  
...  

Ylang-ylang (Cananga odorataHook. F. & Thomson) is one of the plants that are exploited at a large scale for its essential oil which is an important raw material for the fragrance industry. The essential oils extracted via steam distillation from the plant have been used mainly in cosmetic industry but also in food industry. Traditionally,C. odoratais used to treat malaria, stomach ailments, asthma, gout, and rheumatism. The essential oils or ylang-ylang oil is used in aromatherapy and is believed to be effective in treating depression, high blood pressure, and anxiety. Many phytochemical studies have identified the constituents present in the essential oils ofC. odorata. A wide range of chemical compounds including monoterpene, sesquiterpenes, and phenylpropanoids have been isolated from this plant. Recent studies have shown a wide variety of bioactivities exhibited by the essential oils and the extracts ofC. odorataincluding antimicrobial, antibiofilm, anti-inflammatory, antivector, insect-repellent, antidiabetic, antifertility and antimelanogenesis activities. Thus, the present review summarizes the information concerning the traditional uses, phytochemistry, and biological activities ofC. odorata. This review is aimed at demonstrating thatC. odoratanot only is an important raw material for perfume industry but also considered as a prospective useful plant to agriculture and medicine.


Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4664
Author(s):  
Majid Mohammadhosseini ◽  
Alessandro Venditti ◽  
Claudio Frezza ◽  
Mauro Serafini ◽  
Armandodoriano Bianco ◽  
...  

Herein, a comprehensive review is given focusing on the chemical profiles of the essential oils (EOs), non-volatile compounds, ethnobotany, and biological activities of different Haplophyllum (Rutaceae family) species. To gather the relevant data, all the scientific databases, including Scopus, ISI-WOS (Institute of Scientific Information-Web of Science), and PubMed and highly esteemed publishers such as Elsevier, Springer, Taylor and Francis, etc., were systematically retrieved and reviewed. A wide array of valuable groups of natural compounds, e.g., terpenoids, coumarins, alkaloids, lignans, flavonoids, and organic acids have been isolated and subsequently characterized in different organic extracts of a number of Haplophyllum species. In addition, some remarkable antimicrobial, antifungal, anti-inflammatory, anticancer, cytotoxic, antileishmanial, and antialgal effects as well as promising remedial therapeutic properties have been well-documented for some species of the genus Haplophyllum.


Planta Medica ◽  
2018 ◽  
Vol 84 (09/10) ◽  
pp. 627-637 ◽  
Author(s):  
Rosa Tundis ◽  
Monica Loizzo

AbstractThe genus Santolina is a taxonomically complex group of plant species widely distributed in the Mediterranean flora and used in traditional medicine since ancient times for their biological properties, including antimicrobial, anti-inflammatory, antispasmodic, digestive, and analgesic activities. Phytochemical investigations of Santolina species have revealed the presence of terpenoids as the main bioactive constituents of the genus. Coumarins and flavonoids were also identified. This review deals, for the first time, with information on the traditional uses, chemical profile, and biological properties of plants of the genus Santolina in order to provide input for future research prospects.


2019 ◽  
Vol 65 (3) ◽  
pp. 51-63 ◽  
Author(s):  
Artur Adamczak ◽  
Mariola Dreger ◽  
Katarzyna Seidler-Łożykowska ◽  
Karolina Wielgus

Summary Fireweed (Epilobium angustifolium L., Onagraceae) is one of important medicinal plants used especially in the treatment of urogenital disorders, including benign prostatic hyperplasia (BPH) and prostatitis. The therapeutic effects of E. angustifolium extracts comprise antiproliferative, anti-inflammatory, immunomodulatory, antioxidant, and also antimicrobial activities. The aim of the present review was to provide the information on the botany, phytochemistry and traditional uses of E. angustifolium. This plant is a widespread circumboreal species of North America and Eurasia, tolerant in terms of habitat conditions, and often occupying man-made open habitats. Phytochemical studies on E. angustifolium resulted in the identification of about 250 different metabolites, including about 170 substances found for the first time in this plant in the last six years (2014–2019). Fireweed has an abundance of polyphenolic compounds, particularly ellagitannins. Oenothein B and quercetin-3-O-glucuronide are proposed as markers for the identification and standardization of the plant raw material. E. angustifolium exhibits significant phytochemical variability in relation to the geographical origin, plant part and time of harvest/vegetation phase. Survey of the ethnobotanical literature showed that the above-mentioned species has been widely used not only as a medicinal, but also as an edible, honey and decorative plant.


2021 ◽  
Vol 11 (6) ◽  
pp. 13829-13849

Grapes (Vitis vinifera L.) are commonly known grape species that belong to the Vitis genus in the Vitaceae family and come from western Asia and southern Europe. This review consists of traditional uses, phytochemical compounds, nutritional constituents, pharmacological activities, genotoxicological studies, and toxicity studies of V. vinifera. The data were obtained from scientific databases and search engines such as PubMed, Elsevier, Springer, Frontiers, Google Scholar, Scopus, Science Direct, and MDPI. In some countries, grapes used for traditional uses, such as drug therapy for blood-forming, anemia, allergies, wound care, colds and flu, carminative, bronchitis, diarrhea, and anti-phlegm. The main phytochemical compounds in V. vinifera are phenolic compounds, aromatic acids, flavonoids, proanthocyanidins, and stilbenoids. Nutritional constituents can be found in grapevines, i.e., proteins, lipids, carbohydrates, minerals, and vitamins. Parts of the grapevines had a wide variety of biological activities, i.e., antioxidant, antiviral, antiplatelet, antifungal, anticataract, antiobesity, anticholinergic, anti-sunburn, anti-inflammatory, and wound-healing activities. The phytochemical compounds content in each part of the grapevines were different. Each pharmacological activity depends on the grapevine's phytochemical compounds, components used, and extraction type. However, more studies are needed regarding the genotoxicity and toxicity of V. vinifera.


2017 ◽  
Vol 2017 ◽  
pp. 1-22 ◽  
Author(s):  
Fude Yang ◽  
Xiaoxv Dong ◽  
Xingbin Yin ◽  
Wenping Wang ◽  
Longtai You ◽  
...  

Radix Bupleuri (Chaihu) has been used as a traditional medicine for more than 2000 years in China, Japan, Korea, and other Asian countries. Phytochemical studies demonstrated that this plant contains essential oils, triterpenoid saponins, polyacetylenes, flavonoids, lignans, fatty acids, and sterols. Crude extracts and pure compounds isolated from Radix Bupleuri exhibited various biological activities, such as anti-inflammatory, anticancer, antipyretic, antimicrobial, antiviral, hepatoprotective, neuroprotective, and immunomodulatory effects. However, Radix Bupleuri could also lead to hepatotoxicity, particularly in high doses and with long-term use. Pharmacokinetic studies have demonstrated that the major bioactive compounds (saikosaponins a, b2, c, and d) were absorbed rapidly in rats after oral administration of the extract of Radix Bupleuri. This review aims to comprehensively summarize the traditional uses, botany, phytochemistry, pharmacology, toxicology, and pharmacokinetics of Radix Bupleuri reported to date with an emphasis on its biological properties and mechanisms of action.


2020 ◽  
Vol 257 ◽  
pp. 112853 ◽  
Author(s):  
Muhammad Torequl Islam ◽  
Jabed Hasan ◽  
H. M. Shadid Hossain Snigdha ◽  
Eunus S. Ali ◽  
Javad Sharifi-Rad ◽  
...  

2020 ◽  
Vol 26 (16) ◽  
pp. 1838-1865 ◽  
Author(s):  
Vânia C. Graça ◽  
Isabel C.F.R. Ferreira ◽  
Paulo F. Santos

Background: Plants from the Geranium genus, which comprises about 400 species, have been used since ancient times in the practice of traditional medicines throughout the world. Therefore, herbal preparations based on Geranium species have found wide usage for the treatment of a variety of ailments. The aim of this work is to present a review, as comprehensive as possible, of the studies concerning different biological activities of Geranium species. Methods: Relevant data were obtained through systematic computer searches from major reputed scientific databases, particularly Web of Science and Scopus. Occasionally, information issued in primary sources not covered by these databases was also included provided published as peer-reviewed literature. This review covers the literature disclosed till the end of 2018. Results: ccompanying the increasing interest in herbal medicines in general, the evaluation of the biological properties of medicinal plants from the Geranium genus has been addressed thoroughly, mostly over the last two decades. Geranium species are endowed with a number of different biological activities. Herein, we present a survey of the results of the studies concerning these different biological activities. Conclusion: Most studies found in the literature effectively contribute to scientifically validate the beneficial properties of Geranium plants claimed by traditional medicines and medical herbalism and demonstrate that many of them possess evident therapeutic properties.


2021 ◽  
Vol 12 ◽  
Author(s):  
Innocent Uzochukwu Okagu ◽  
Joseph Chinedum Ndefo ◽  
Emmanuel Chigozie Aham ◽  
Chibuike. C. Udenigwe

The health benefits and toxicity of plant products are largely dependent on their secondary metabolite contents. These compounds are biosynthesized by plants as protection mechanisms against environmental factors and infectious agents. This review discusses the traditional uses, phytochemical constituents and health benefits of plant species in genus Zanthoxylum with a focus on cancer, microbial and parasitic infections, and sickle cell disease as reported in articles published from 1970 to 2021 in peer-reviewed journals and indexed in major scientific databases. Generally, Z. species are widely distributed in Asia, America and Africa, where they are used as food and for disease treatment. Several compounds belonging to alkaloids, flavonoids, terpenoids, and lignans, among others have been isolated from Z. species. This review discusses the biological activities reported for the plant species and their phytochemicals, including anticancer, antibacterial, antifungal, antiviral, anti-trypanosomal, antimalarial and anti-sickling properties. The safety profiles and suggestions for conservation of the Z. species were also discussed. Taken together, this review demonstrates that Z. species are rich in a wide range of bioactive phytochemicals with multiple health benefits, but more research is needed towards their practical application in the development of functional foods, nutraceuticals and lead compounds for new drugs.


Author(s):  
Manish Kapoor ◽  
Gurdeep Kaur ◽  
Navneet Kaur ◽  
Chanchal Sharma ◽  
Kajal Batra ◽  
...  

The genus Hibiscus belongs to the mallow family, Malvaceae comprising of about 275 species growing in tropical and sub tropical areas. The various species of genus Hibiscus have been used as traditional medicine all over the world. There are numerous reports of their traditional medicinal uses in various countries like India, Nigeria, China, and Srilanka etc. to cure various ailments such as hypertension, cardiac diseases, stomach-ache, urine problems, skin diseases and many more. Based on the historical knowledge, various pharmacological and phytochemical studies on some species of the genus Hibiscus have been done. Nevertheless, there are no up-to-date articles published which can provide an overview of pharmacological effects of the genus Hibiscus. Therefore, the main objective of the review article is to provide a systematic comprehensive summary of traditional uses, phytochemistry and pharmacology of the genus Hibiscus and to build up a correlation between its traditional ethano-botanical uses and pharmacological activities so as to find some advanced research opportunities in this field. The given information on the ethano-botanical uses, phytoconstituents and various medicinal properties of the genus Hibiscus was gathered from the online scientific databases through search in Google, Google Scholar, Science Direct, NCBI, Pubmed, Springer Link, Research Gate by using some keywords as. Besides these websites other published literature and unpublished Ph.D. thesis and M.Sc. dissertation were also consulted. Previously conducted research revealed that the genus contains good amount of phytoconstituents such as antioxidants, phytosterols, saponins, lignin, essential oils, glycosides, and anthocyanins etc. Presence of these bioactive compounds in the crude extracts of the plants make it suitable for various medicinal properties like anti inflammatory, anti-diabetic, anti-obesity, anti-proliferative, anti-ulcer, hypersensitive, hypolipidemic, hepatoprotective, nephroprotective and many more. Additionally, this review article showed that mainly two species of the genus i.e. H. rosa-sinensis and H. sabdariffa have been explored for their pharmacological activities. There are few reports on some other species like H. tiliaceous, H. microanthus, H. asper, H. acetosella. This review highlights the medicinal potential of the plant Hibiscus due to its unique blend of phytochemicals. These phytoconstituents can be further assessed and subjected to clinical trials for their proper validations. Although large amount of the data regarding pharmacological effects has already been added to the existing reservoir but still potential of certain species like H. radiatus, H. hirtus, H. moschetous, H. trionum and many more is not yet unveiled and can be considered as future prospects that need to be worked out.  Graphical Abstract: 


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