scholarly journals Aqueous-Mediated Synthesis and Characterization of Gelatin Methacryloyl for Biomedical Applications

2021 ◽  
Vol 12 (5) ◽  
pp. 6269-6279

In recent years, gelatin methacryloy¬l (GelMA)-based hydrogels have been widely used in many biomedical applications, particularly tissue engineering, due to their biocompatibility and tunable physicochemical, mechanical, and other functional properties. Phosphate buffer saline (PBS) or carbonate-bicarbonate buffer are frequently used to make GelMA. In this article, the authors provide an elegant aqueous-mediated synthesis and characterization of GelMA. The experimental conditions were optimized and extensively discussed. The results of proton nuclear magnetic resonance (1H NMR) and Fourier transform infrared spectroscopy (FTIR) confirmed the formation of GelMA with characteristic absorption peaks and chemical functional groups. The morphological analysis done with scanning electron microscopy (SEM) showed the porous nature of the GelMA with an average pore size of 80 microns. It was also found that the gelation properties of aqueous-mediated GelMA hydrogel were highly tunable by varying the percentage of gel concentration, which yields a wide range of tunable physicochemical properties. The preparation of this kind of aqueous-mediated GelMA is cost-effective compared to their counterparts and easy to prepare in laboratory settings with high yield under optimal conditions.

2006 ◽  
Vol 514-516 ◽  
pp. 1005-1009 ◽  
Author(s):  
José V. Araújo ◽  
J.A. Lopes da Silva ◽  
Margarida M. Almeida ◽  
Maria Elisabete V. Costa

Porous chitosan/brushite composite scaffolds were prepared by a freeze-drying technique, starting from brushite suspensions in chitosan solutions. The obtained scaffolds showed a regular macroporous and interconnected structure with brushite particles uniformly distributed in the chitosan matrix. The variation of the brushite concentration affected the microstructure of the final freeze-dried scaffold, in particular, its porosity and its average pore size. The yield strengths of the composite scaffolds could also be improved by the increase of the brushite content.


2021 ◽  
Author(s):  
Meghan Winterlich ◽  
Darragh McHugh ◽  
Evan O'Toole ◽  
Katerina Skordi ◽  
Ciaran O'Malley ◽  
...  

Metal organic frameworks (MOFs) have attracted considerable attention in recent years due to their use in a wide range of environmental, industrial and biomedical applications. The employment of benzophenone-4,4’-dicarboxylic acid...


Photonics ◽  
2021 ◽  
Vol 8 (7) ◽  
pp. 255
Author(s):  
Marie Tahon ◽  
Silvio Montresor ◽  
Pascal Picart

Digital holography is a very efficient technique for 3D imaging and the characterization of changes at the surfaces of objects. However, during the process of holographic interferometry, the reconstructed phase images suffer from speckle noise. In this paper, de-noising is addressed with phase images corrupted with speckle noise. To do so, DnCNN residual networks with different depths were built and trained with various holographic noisy phase data. The possibility of using a network pre-trained on natural images with Gaussian noise is also investigated. All models are evaluated in terms of phase error with HOLODEEP benchmark data and with three unseen images corresponding to different experimental conditions. The best results are obtained using a network with only four convolutional blocks and trained with a wide range of noisy phase patterns.


RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9076-9085
Author(s):  
Kanchan Yadav ◽  
Megha Das ◽  
Nurul Hassan ◽  
Archana Mishra ◽  
Jayeeta Lahiri ◽  
...  

A novel nanodot-using protein has been synthesized for the live cell imaging and drug delivery of melatonin in breast cancer cells. Its unique properties hold potential for various biomedical applications in the field of bioimaging and drug delivery.


2019 ◽  
Vol 28 (4) ◽  
pp. 265-272 ◽  
Author(s):  
Hamou Gherras ◽  
Ahmed Yahiaoui ◽  
Aicha Hachemaoui ◽  
Abdelkader Belfedal ◽  
Abdelkader Dehbi ◽  
...  

The use of conductive polymers as a substitute for metallic conductors and semiconductors has attracted much attention in the literature. In particular, aromatic heterocyclic polymers constitute an important class since they possess chemical and electrical stability in both the oxidized (doped) and neutral (undoped) state. A series of poly(pyrrole- co-2-nitrocinnamaldehyde) were obtained via the condensation of pyrrole and 2-nitrocinnamaldehyde in chloroform using acid exchanged montmorillonite clay called maghnite-H+ as an efficient catalyst. The conjugated copolymer was characterized using proton nuclear magnetic resonance, ultraviolet–visible spectroscopy, Fourier transform infrared spectroscopy, and scanning electron microscopy.


2005 ◽  
Vol 19 (12) ◽  
pp. 1215-1219 ◽  
Author(s):  
G. M. Mizanur Rahman ◽  
H. M. ‘Skip’ Kingston ◽  
Matt Pamukcu

2007 ◽  
Vol 12 (4) ◽  
pp. 574-582 ◽  
Author(s):  
Nelson Heriberto de Almeida Camargo ◽  
O. J. Bellini ◽  
Enori Gemelli ◽  
M. Tomiyama

Nanostructured materials have been largely studied in the last few years because they have a great potential to applications in different fields like physics, chemistry, biology, mechanic and medicine. Synthesis and characterization of nanostructured materials is a subject of great interest involving science, market, politicians, government and society. The nanostructured materials are in demand in biomedical area, mainly the bioceramics composed of calcium phosphates (Ca/P), which have an excellent biocompatibility and mineralogical characteristics similar to those of bones. The aim of this work was to optimize the method of powder synthesis of nanostructured calcium phosphate and of nanocomposites composed of calcium phosphate//SiO2n, containing 5, 10 and 15% (in volume) of nanometric silica (SiO2n). The results are expressed according to the method of synthesis, mineralogical and morphological characterization, and thermal behavior for the different compositions of the nanostructured powder synthesized.


2008 ◽  
Vol 62 (6-7) ◽  
pp. 914-917 ◽  
Author(s):  
Ping Ou ◽  
Gang Xu ◽  
Zhaohui Ren ◽  
Xiaohong Hou ◽  
Gaorong Han

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