scholarly journals Environmental Impact for 3D Bone Tissue Engineering Scaffolds Life Cycle: An Assessment

2021 ◽  
Vol 12 (5) ◽  
pp. 6504-6515

With the development of additive manufacturing technology, 3D bone tissue engineering scaffolds have evolved. Bone tissue engineering is one of the techniques for repairing bone abnormalities caused by a variety of circumstances, such as injuries or the need to support damaged sections. Many bits of research have gone towards developing 3D bone tissue engineering scaffolds all across the world. The assessment of the environmental impact, on the other hand, has received less attention. As a result, the focus of this study is on developing a life cycle assessment (LCA) model for 3D bone tissue engineering scaffolds and evaluating potential environmental impacts. One of the methodologies to evaluating a complete environmental impact assessment is life cycle assessment (LCA). The cradle-to-grave method will be used in this study, and GaBi software was used to create the analysis for this study. Previous research on 3D bone tissue engineering fabrication employing poly(ethylene glycol) diacrylate (PEGDA) soaked in dimethyl sulfoxide (DMSO), and diphenyl (2,4,6-trimethylbenzoyl) phosphine oxide (TPO) as a photoinitiator will be reviewed. Meanwhile, digital light processing (DLP) 3D printing is employed as the production technique. The GaBi program and the LCA model developed to highlight the potential environmental impact. This study shows how the input and output of LCA of 3D bone tissue engineering scaffolds might contribute to environmental issues such as air, freshwater, saltwater, and industrial soil emissions. The emission contributing to potential environmental impacts comes from life cycle input, electricity and transportation consumption, manufacturing process, and material resources. The results from this research can be used as an indicator for the researcher to take the impact of the development of 3D bone tissue engineering on the environment seriously.

2021 ◽  
Author(s):  
Nurul Ainina Nadhirah Tajurahim ◽  
Salwa Mahmood ◽  
Muhamad Zameri Mat Saman ◽  
Nor Hasrul Akhmal Ngadiman

Abstract The bone tissue engineering scaffolds are one of the methods to repairing bone defects caused by various factors. According to modern tissue engineering technology, three-dimensional (3D) printing technology for bone tissue engineering provides a temporary basis for the creation of biological replacements. Through the generated 3D bone tissue engineering scaffolds from previous studies, the assessment to evaluate the environmental impact has shown less attention in research. Purposes — The main purpose of this research at developing the life cycle assessment (LCA) Model for 3D bone tissue engineering scaffolds of 3D gel-printing technology and present the analysis technique of LCA from cradle-to-gate to assess the environmental impacts from material selection and manufacturing processes. LCA is indeed a valuable tool for conducting a complete environmental impact assessment of 3D bone tissue engineering scaffolds. Method — The methodology of this research is based on the LCA Model through the application of GaBi software according to ISO 14040 standards. The parameters for the developed LCA Model were determined through the system boundaries of 3D gel-printing technology. Acrylamide, citric acid, N,N-Dimethylaminopropyl acrylamide, deionized water, and 2-Hydroxyethyl acrylate were selected as the material resources. Meanwhile, the 3D gel-printing technology was used as the manufacturing processes in the system boundary. Besides, consideration of LCA Model was given to all phases of LCA approach set out in the regulatory framework. The analytical findings are presented through graphs generated by GaBi software based on the inventory of each material and manufacturing process used. Results — The environmental impact was assessed in the 3D gel-printing technology and the result obtained showed the environmental impact of global warming potential (GWP). All of the emissions contribute to GWP have been identified such as emission to air, freshwater, seawater, and industrial soil. The quantity of flows that contributes to GWP comes from electricity consumption, manufacturing process, and material resources. Conclusions — The input data is understood to be resources required whereas, the output is the emission of the different compartments such as emission to air, water, and soil. The issue of GWP is represented by the GWP impacts category. Any emissions to air, water, and soil that contributes to GWP are classified as contributors. Throughout the results, it can be described that the impact category in the system comes from the linking process of specific resources to the specific environmental issue. Thus, it is believed that the development of LCA Model is very helpful to graphically assess the potential environmental impact associated with the material and manufacturing processes of a product’s life cycle. Besides, the data analysis of the results is expected to use for improving the performance at the material and manufacturing process of the product life cycle. Also, it is to makes the production process more environmentally friendly.


Author(s):  
S. Boughrara ◽  
M. Chedri ◽  
K. Louhab

The aim of this study is the use of Life Cycle Assessment, to evaluate the impact generated by cement manufactory situated in Sour EL Ghozlane town in Algeria country, which use the dry process to produce cement Portland. The LCA method is used for compiling and examining the inputs and outputs of energy, raw material and environmental impacts directly attributable to the manufacture and functioning of a product throughout its life. It is also used to determine element and energy contributing to each impact evaluated. Potentials impacts are evaluated using the SimaProV.7.1 software and IMPACT2000+ method in this study.


2021 ◽  
Vol 11 (3) ◽  
pp. 1160
Author(s):  
Antonella Accardo ◽  
Giovanni Dotelli ◽  
Marco Luigi Musa ◽  
Ezio Spessa

This paper presents the results of an environmental assessment of a Nickel-Manganese-Cobalt (NMC) Lithium-ion traction battery for Battery Electric Light-Duty Commercial Vehicles (BEV-LDCV) used for urban and regional freight haulage. A cradle-to-grave Life Cycle Inventory (LCI) of NMC111 is provided, operation and end-of-life stages are included, and insight is also given into a Life Cycle Assessment of different NMC chemistries. The environmental impacts of the manufacturing stages of the NMC111 battery are then compared with those of a Sodium-Nickel-Chloride (ZEBRA) battery. In the second part of the work, two electric-battery LDCVs (powered with NMC111 and ZEBRA batteries, respectively) and a diesel urban LDCV are analysed, considering a wide set of environmental impact categories. The results show that the NMC111 battery has the highest impacts from production in most of the impact categories. Active cathode material, Aluminium, Copper, and energy use for battery production are the main contributors to the environmental impact. However, when vehicle application is investigated, NMC111-BEV shows lower environmental impacts, in all the impact categories, than ZEBRA-BEV. This is mainly due to the greater efficiency of the NMC111 battery during vehicle operation. Finally, when comparing BEVs to a diesel LDCV, the electric powertrains show advantages over the diesel one as far as global warming, abiotic depletion potential-fossil fuels, photochemical oxidation, and ozone layer depletion are concerned. However, the diesel LDCV performs better in almost all the other investigated impact categories.


2020 ◽  
Vol 76 (3) ◽  
pp. 137-153
Author(s):  
Harnpon Phungrassami ◽  
Phairat Usubharatana

Environmental impacts of fishery production have resulted in increased concern and awareness. Thailand, as one of the largest global fish exporters, faces challenges related to environmental problems caused by fishery processes. Here, the environmental impact of Thai surimi production was estimated based on life cycle assessment (LCA) methodology, focusing specifically on two Thai surimi products made from goatfish and ponyfish caught within the southern region of Thailand. Three impact categories where explored: global warming, acidification and eutrophication. Life cycle impacts were calculated for one kg of product using both mass and economic allocations. Results of this study indicated that goatfish has lower impacts than ponyfish for all the impact categories. Fuel consumption during the fishery phase and electricity consumption during processing were the main parameters leading to most of the considered environmental impacts. The value of Global Warming  Potential(GWP) ranged within 1.3‒3.0 kg CO2eq for goatfish and 2.2‒7.1 kg CO2eq ponyfish depending on the allocation method. The acidification impact of goatfish and ponyfish were revealed at 3.2‒7.3 gSO2eq and 12.7‒39.7 gSO2eq, respectively. The eutrophication of goatfish and ponyfish were 0.7‒1.6 gPO4eq and 2.5‒8.1 gPO4eq, respectively. Sensitivity analysis of fuel consumption, electricity consumption, product yield and allocation method were evaluated.


2016 ◽  
Vol 19 (2) ◽  
pp. 93-100
Author(s):  
Lalita El Milla

Scaffolds is three dimensional structure that serves as a framework for bone growth. Natural materials are often used in synthesis of bone tissue engineering scaffolds with respect to compliance with the content of the human body. Among the materials used to make scafffold was hydroxyapatite, alginate and chitosan. Hydroxyapatite powder obtained by mixing phosphoric acid and calcium hydroxide, alginate powders extracted from brown algae and chitosan powder acetylated from crab. The purpose of this study was to examine the functional groups of hydroxyapatite, alginate and chitosan. The method used in this study was laboratory experimental using Fourier Transform Infrared (FTIR) spectroscopy for hydroxyapatite, alginate and chitosan powders. The results indicated the presence of functional groups PO43-, O-H and CO32- in hydroxyapatite. In alginate there were O-H, C=O, COOH and C-O-C functional groups, whereas in chitosan there were O-H, N-H, C=O, C-N, and C-O-C. It was concluded that the third material containing functional groups as found in humans that correspond to the scaffolds material in bone tissue engineering.


2021 ◽  
Vol 13 (9) ◽  
pp. 5322
Author(s):  
Gabriel Zsembinszki ◽  
Noelia Llantoy ◽  
Valeria Palomba ◽  
Andrea Frazzica ◽  
Mattia Dallapiccola ◽  
...  

The buildings sector is one of the least sustainable activities in the world, accounting for around 40% of the total global energy demand. With the aim to reduce the environmental impact of this sector, the use of renewable energy sources coupled with energy storage systems in buildings has been investigated in recent years. Innovative solutions for cooling, heating, and domestic hot water in buildings can contribute to the buildings’ decarbonization by achieving a reduction of building electrical consumption needed to keep comfortable conditions. However, the environmental impact of a new system is not only related to its electrical consumption from the grid, but also to the environmental load produced in the manufacturing and disposal stages of system components. This study investigates the environmental impact of an innovative system proposed for residential buildings in Mediterranean climate through a life cycle assessment. The results show that, due to the complexity of the system, the manufacturing and disposal stages have a high environmental impact, which is not compensated by the reduction of the impact during the operational stage. A parametric study was also performed to investigate the effect of the design of the storage system on the overall system impact.


2021 ◽  
Vol 13 (5) ◽  
pp. 2525
Author(s):  
Camila López-Eccher ◽  
Elizabeth Garrido-Ramírez ◽  
Iván Franchi-Arzola ◽  
Edmundo Muñoz

The aim of this study is to assess the environmental impacts of household life cycles in Santiago, Chile, by household income level. The assessment considered scenarios associated with environmental policies. The life cycle assessment was cradle-to-grave, and the functional unit considered all the materials and energy required to meet an inhabitant’s needs for one year (1 inh/year). Using SimaPro 9.1 software, the Recipe Midpoint (H) methodology was used. The impact categories selected were global warming, fine particulate matter formation, terrestrial acidification, freshwater eutrophication, freshwater ecotoxicity, mineral resource scarcity, and fossil resource scarcity. The inventory was carried out through the application of 300 household surveys and secondary information. The main environmental sources of households were determined to be food consumption, transport, and electricity. Food consumption is the main source, responsible for 33% of the environmental impacts on global warming, 69% on terrestrial acidification, and 29% on freshwater eutrophication. The second most crucial environmental hotspot is private transport, whose contribution to environmental impact increases as household income rises, while public transport impact increases in the opposite direction. In this sense, both positive and negative environmental effects can be generated by policies. Therefore, life-cycle environmental impacts, the synergy between policies, and households’ socio-economic characteristics must be considered in public policy planning and consumer decisions.


2021 ◽  
Vol 13 (13) ◽  
pp. 7386
Author(s):  
Thomas Schaubroeck ◽  
Simon Schaubroeck ◽  
Reinout Heijungs ◽  
Alessandra Zamagni ◽  
Miguel Brandão ◽  
...  

To assess the potential environmental impact of human/industrial systems, life cycle assessment (LCA) is a very common method. There are two prominent types of LCA, namely attributional (ALCA) and consequential (CLCA). A lot of literature covers these approaches, but a general consensus on what they represent and an overview of all their differences seems lacking, nor has every prominent feature been fully explored. The two main objectives of this article are: (1) to argue for and select definitions for each concept and (2) specify all conceptual characteristics (including translation into modelling restrictions), re-evaluating and going beyond findings in the state of the art. For the first objective, mainly because the validity of interpretation of a term is also a matter of consensus, we argue the selection of definitions present in the 2011 UNEP-SETAC report. ALCA attributes a share of the potential environmental impact of the world to a product life cycle, while CLCA assesses the environmental consequences of a decision (e.g., increase of product demand). Regarding the second objective, the product system in ALCA constitutes all processes that are linked by physical, energy flows or services. Because of the requirement of additivity for ALCA, a double-counting check needs to be executed, modelling is restricted (e.g., guaranteed through linearity) and partitioning of multifunctional processes is systematically needed (for evaluation per single product). The latter matters also hold in a similar manner for the impact assessment, which is commonly overlooked. CLCA, is completely consequential and there is no limitation regarding what a modelling framework should entail, with the coverage of co-products through substitution being just one approach and not the only one (e.g., additional consumption is possible). Both ALCA and CLCA can be considered over any time span (past, present & future) and either using a reference environment or different scenarios. Furthermore, both ALCA and CLCA could be specific for average or marginal (small) products or decisions, and further datasets. These findings also hold for life cycle sustainability assessment.


Micromachines ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 664
Author(s):  
Haiyuan Zhao ◽  
Yafeng Han ◽  
Chen Pan ◽  
Ding Yang ◽  
Haotian Wang ◽  
...  

In order to obtain scaffold that can meet the therapeutic effect, researchers have carried out research on irregular porous structures. However, there are deficiencies in the design method of accurately controlling the apparent elastic modulus of the structure at present. Natural bone has a gradient porous structure. However, there are few studies on the mechanical property advantages of gradient bionic bone scaffold. In this paper, an improved method based on Voronoi-tessellation is proposed. The method can get controllable gradient scaffolds to fit the modulus of natural bone, and accurately control the apparent elastic modulus of porous structure, which is conducive to improving the stress shielding. To verify the designed structure can be fabricated by additive manufacturing, several designed models are obtained by SLM and EBM. Through finite element analysis (FEA), it is verified that the irregular porous structure based on Voronoi-tessellation is more stable than the traditional regular porous structure of the same structure volume, the same pore number and the same material. Furthermore, it is verified that the gradient irregular structure has a better stability than the non-gradient structure. An experiment is conducted successfully to verify the stability performance got by FEA. In addition, a dynamic impact FEA is also performed to simulate impact resistance. The result shows that the impact resistance of the regular porous structure, the irregular porous structure and the gradient irregular porous structure becomes better in turn. The mechanical property verification provides a theoretical basis for the structural design of gradient irregular porous bone tissue engineering scaffolds.


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