scholarly journals Findings of Brain Imaging among Tuberculous Meningitis Patients: A Study of 30 Cases in Bangladesh

2019 ◽  
Vol 6 (1) ◽  
pp. 8-11
Author(s):  
Abul Kalam Mohammed Shoab ◽  
Mostafa Hosen ◽  
Syed Abul Foez ◽  
Md Shaheen Wadud ◽  
Habibur Rahman ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Infectious Diseases ◽  
Brain Imaging ◽  
Tuberculous Meningitis ◽  
Health Hazard ◽  
Brain Lesions ◽  
College Hospital ◽  
Medical College ◽  
The Brain

Background: Tuberculous meningitis is a serious health hazard and difficult to diagnose. Objectives: The purpose of the present study was to observe the role of CT/MRI in TBM diagnosis. Methodology: This was a retrospective study done from January 2010 to December 2011 for a period of two (02) years. Patients of TBM were reviewed in a medical college hospital of Bangladesh. Results: A total number of reviewed 30 TBM patients; among them 11 cases were confirmed TBM patients and 19 were probable patients. Brain imaging (CT/MRI) was performed in 15 cases. The use of brain imaging allowed the Brain lesions in 93.3% patients. Conclusion: Brain imaging was done in 15 out of 30 TBM patients and most of them (14/15) had got various forms of radiological abnormalities that aid in diagnosis and monitor of disease progression in TBM. Bangladesh Journal of Infectious Diseases, June 2019; 6(1):8-11

scholarly journals Sinovenous Abnormalities in Patients of Idiopathic Intracranial Hypertension

2018 ◽  
Vol 26 ◽  
pp. 53-56
Author(s):  
M Pervez Amin ◽  
Pijush Kumar Kundu ◽  
M Munzur Alahi ◽  
Mukul Kumar Sarkar ◽  
M Ahmed Ali ◽  
...  
Keyword(s):  
Intracranial Hypertension ◽  
Idiopathic Intracranial Hypertension ◽  
Transverse Sinus ◽  
College Hospital ◽  
Medical College ◽  
Significant Difference ◽  
History Of ◽  
History Of Use ◽  
The Brain

Idiopathic Intracranial Hypertension is a disease of unknown aetiology common in obese females and presents with headache, papilledema, raised CSF opening pressure, no abnormalities in CSF examination and no abnormality on CT scan or MRI of the Brain. Sinovenous abnormalities are commonly detected in patients of IIH by different neuroimaging techniques. But the exact role of these sinovenous abnormalities in the causation of the disease or whether they are an effect of the disease is not yet known. Nor has a ‘gold standard’ investigation been established yet for detection of the sinovenous abnormalities. This study was done to detect the presence of sinovenous abnormalities in IIH patients by performing a Magnetic Resonance Venography of the brain. All 33 patients of IIH who presented to Rajshahi Medical College Hospital during the study period from June 2009 to May 2010 were included in the study. There were 30 females and 3 males having a F:M ratio of 10:1. 91% of the patients were between 20 and 35 years of age and most of them were married housewives. 63.64% patients had history of use of oral contraceptives. Unusually 51.52% of the patients had a BMI less than 25 indicating that they were not even overweight (BMI 25 to 30). Only 6% of the patients had BMI > 30 indicating that they were obese. Headache and papilloedema were present in all patients but visual difficulties were present only in 54.54% of the patients. Abnormalities in MRV of the brain were detected in 27.27% (9/33) of the patients and transverse sinus hypoplasia was the commonest finding (88.89% - 8/9 patients). There was no statistically significant difference in the findings of MRV abnormalities between the males and females or among the patients having BMI less or more than 25TAJ 2013; 26: 53-56

Abstract TP147: Central Post Stroke Pain: A Systematic Review

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Jonathan Singer ◽  
Alyssa Conigliaro ◽  
Elizabeth Spina ◽  
Susan Law ◽  
Steven Levine
Keyword(s):  
Systematic Review ◽  
Brain Imaging ◽  
Pain Scale ◽  
Post Stroke ◽  
Underlying Causes ◽  
Single Question ◽  
Thalamic Region ◽  
The Brain ◽  
A Current

Background: Central Post Stroke Pain (CPSP) is reportedly due to strokes in the thalamic region (Dishinbition Theory); however, the Central Imbalance Theory states that CPSP is due to damage to the spinothalamic pathway (STP). Aims: 1) Clarify the role of thalamic strokes and STP damage in CPSP patients. 2) Gain a current understanding of anatomic substrates, brain imaging, and treatment of CPSP. Methods: Two independent reviewers systematically reviewed PUBMED, CINAHL and Web of Science for studies including original, clinical studies and randomized controlled trials (RCTs) using PRISMA guidelines. Studies had to assess CPSP, using a single question or pain scale. Results: Search from January – July 2016, identifying 731 publications. We extracted data from 23 studies and categorized the articles’ aims into 4 sections: somatosensory deficits (5 studies), STP (3 studies), brain imaging (7 studies), and RCTs (8 studies). Somatosensory studies showed high rates of CPSP; however, the underlying causes of these deficits were unclear. Most studies did not refer to stroke location as playing a role in CPSP, but that pathways may. STP studies displayed consistent evidence that the STP plays a major role in CPSP, delineating that CPSP can occur even when the stroke is not in the thalamic region but in other regions (e.g. cerebellum, basal ganglia, medulla). Four of the brain imaging studies found CPSP not related and 3 found it was related to thalamic strokes. All 7 studies had major limitations including sample size, no control groups, and selection bias. RCTs were mostly negative, but brain stem and motor cortex stimulation studies showed the most promise. Conclusions: While CPSP has been linked to the thalamic region since the early 1900’s, the peer-reviewed literature showed equivocal results when examining location of stroke. Our systematic review suggests damage to the STP is associated with CPSP and this could provide insights into mechanisms and treatment. Moreover, historical connection of strokes in the thalamic region and CPSP should be reevaluated as many studies noted that strokes in other regions of the brain also produce CPSP.

scholarly journals Evaluation of role of laparoscopy in determining etiology of infertility

2017 ◽  
Vol 6 (12) ◽  
pp. 5322
Author(s):  
Hema K. R. ◽  
Lalitha H. S.
Keyword(s):  
Diagnostic Laparoscopy ◽  
Secondary Infertility ◽  
Peritoneal Disease ◽  
College Hospital ◽  
Medical College ◽  
Uterine Anomalies ◽  
Morphological Defects ◽  
Indispensable Tool ◽  
Infertility Patients

Background: Although population explosion is a major problem in India, infertility appears to be a problem in 5-15% of Indian population. All these patients require evaluation. Laparoscopy plays a valuable role in the diagnosis of infertility. After thorough clinical examination and specific investigations, diagnostic laparoscopy is performed to detect patency of tubes, morphological defects in uterus, ovaries and tuboperitoineal factors. This study was conducted to assess the role of diagnostic laparoscopy in the investigation of female infertility and to evaluate the various causes of infertility like endometriosis, PCOD tubal and peritoneal factors, uterine anomalies, tuberculosis etc. by using diagnostic laparoscopy.Methods: Study was carried out in 60 infertile patients attending outpatient department of hospitals attached to Sri Siddhartha Medical College Hospital, Tumkur.  Both primary and secondary infertility patients who were anxious to conceive and undergo diagnostic laparoscopy were evaluated. Those who were not willing and who were contraindicated for the procedure were excluded.Results: Diagnostic laparoscopy was performed in 72% of primary and 28% of secondary infertility patients. Majority of the patients of primary infertility were in age group 21-25 years and that of secondary were between 26-30 years. Majority of patients in both the groups had duration of 1-5 year of infertility. In our study tubal factors (50%) contributed to majority of the infertility causes. Complication rate was minimum and was comparable to other standard studies.Conclusions: Laparoscopic is the gold standard for diagnosing tubal and peritoneal disease, endometriosis and other pelvic pathology, because no other imaging technique gives the same degree of sensitivity or specificity. Hence diagnostic laparoscopy is an indispensable tool in the evaluation in the evaluation infertility.

scholarly journals HISTOMORPHOLOGICAL SPECTRUM OF LESIONS OF HYSTERECTOMY SPECIMENS IN GCS MEDICAL COLLEGE, HOSPITALAND RESEARCH CENTER, AHMEDABAD : A STUDY OF 100 CASES

2020 ◽  
pp. 80-82
Author(s):  
Shweta Shah ◽  
S.K. Suri ◽  
Ami Shah
Keyword(s):  
Retrospective Study ◽  
Age Groups ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Medical College Hospital ◽  
Research Centre ◽  
Age Group ◽  
Gynaecological Surgery ◽  
College Hospital ◽  
Medical College

Background: Most frequently performed gynaecological surgery is hysterectomy. The prevalence of hysterectomy varies within different regions. There are mainly two types of hysterectomies according to which part of uterus is removed. The main types of hysterectomy are total and subtotal or partial hysterectomy. The hysterectomy can be performed by three routes abdominal, laproscopic and vaginal hysterectomy. The main objective of our study is to know most common pathology and different age groups of the patients underwent hysterectomy. Materials and Methods: In this retrospective study was carried during period 6 months, at GCS medical college, hospital and research centre, Ahmedabad. Total 100 hysterectomy specimens were analyzed for histopathological lesions. We had taken the clinical and histopathological findings of these cases from the records of department of pathology, GCS medical college , hospital and research centre. Results: In our study of 100 cases, most common age group underwent hysterectomy was 40-49 years and least common age group was 20-29 years. Type of hysterectomy performed most commonly in this study was total abdominal hysterectomy with bilateral salpingoophorectomy. Most of lesions were seen in the myometrium 42 cases (42%), Endometrium 32 cases (32%), Cervix 16 cases (16%) and Ovary 10 cases (10%). Hysterectomy remains the widely used treatment modality.

scholarly journals Clinical features of a Chinese female nongestational choriocarcinoma cohort: a retrospective study of 37 patients

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Yuming Shao ◽  
Yang Xiang ◽  
Fang Jiang ◽  
Boju Pan ◽  
Xirun Wan ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Clinical Laboratory ◽  
Age Of Onset ◽  
Survival Rates ◽  
Malignant Neoplasm ◽  
Complete Response ◽  
College Hospital ◽  
Medical College ◽  
Gestational Choriocarcinoma ◽  
Therapeutic Outcomes

Abstract Background Choriocarcinoma is a rare malignant neoplasm, which is classified as either gestational choriocarcinoma or nongestational choriocarcinoma. The purpose of this study was to examine the clinical characteristics of Chinese female nongestational choriocarcinoma patients and discuss our experience in treating this rare disease. Results We conducted a single-center retrospective study on a sample of 37 nongestational choriocarcinoma patients who were diagnosed and treated at Peking Union Medical College Hospital from March 1982 to March 2020. Their demographic, clinical, laboratory, and therapeutic data were collected. Detailed information was available for all 37 individuals in our sample. The primary lesions included 34 in the ovaries, 2 in the pituitary and 1 in the stomach. The median age of onset was 22 years, and the median follow-up period spanned 41 months. The lungs (40.5%) were the most commonly observed metastatic site. All subjects were treated with surgery and multidrug chemotherapies, and a median of 4.0 courses was required to achieve complete remission. The overall complete response rate, relapse rate, and 3-year and 5-year survival rates were 81.1%, 16.7%, 80.0%, and 75.5%, respectively. Conclusions Nongestational choriocarcinoma can be managed well using surgery and multidrug chemotherapies, but the overall outcome of nongestational choriocarcinoma is still worse than that of gestational choriocarcinoma. Mixed nongestational choriocarcinoma seems to have similar therapeutic outcomes as pure tumors.

scholarly journals Cause of Neonatal Sepsis: Transplacental vs Environmental

2013 ◽  
Vol 5 (3) ◽  
pp. 132-134
Author(s):  
Swati Shiradkar ◽  
Gauri N Bapat ◽  
Manjushree H Bhalchandra ◽  
Shubhangi Mande ◽  
Mangala Bansal
Keyword(s):  
South Asian ◽  
Health Professionals ◽  
Neonatal Sepsis ◽  
Carrier State ◽  
Blood Cultures ◽  
Transplacental Transmission ◽  
College Hospital ◽  
Nasal Carrier ◽  
Medical College

ABSTRACT Objectives To study the role of transplacental transmission and environmental factors in neonatal sepsis (0-3) days and incidence of early neonatal sepsis in obstetrics and gynecology wards of MGM Medical College Hospital. Materials and methods The study was carried out on 100 full term women and their babies who delivered in MGM hospital. Their cord blood cultures were done. The nasal carrier state for Staphylococcus aureus (S. aureus) in all the health professionals working in labor room was also studied. Results S. aureus was the most common organism grown in cord cultures of woman who delivered vaginally. None of the babies followed in wards showed any Sign of sepsis in first 72 hours. More than 50% of health professionals working in labor room were carriers of S. aureus. Conclusion S. aureus is having environmental source and it causes late neonatal sepsis so none of the babies developed any Sign of sepsis in first 72 hours of life. Other organisms isolated probably responded to intrapartum antibiotics or maternal immunity played its role and so babies did not showed any s/o sepsis in first 3 days. How to cite this article Bapat GN, Shiradkar S, Bhalchandra MH, Mande S, Bansal M. Cause of Neonatal Sepsis: Transplacental vs Environmental. J South Asian Feder Obst Gynae 2013;5(3):132-134.

scholarly journals Role of Maternal Smokeless Tobacco Ingestion During Pregnancy in Delivery of Preterm Babies

2017 ◽  
Vol 40 (3) ◽  
pp. 135-138
Author(s):  
Farzana Rahman Munmun ◽  
Md Ekhlasur Rahman ◽  
Ahmed Ferdous Jahangir ◽  
Md Shamsul Arefin Patwary ◽  
Abu Sayeed Chowdhury ◽  
...  
Keyword(s):  
Smokeless Tobacco ◽  
Adverse Pregnancy Outcome ◽  
Retrospective Case ◽  
College Hospital ◽  
Term Neonates ◽  
Medical College ◽  
History Of ◽  
Preterm Babies ◽  
Adverse Pregnancy

Background:Smokeless tobacco is an established cause of adverse pregnancy outcome. Preterm deliveries are quite high(14%) in our country and approximately 39% women in Bangladesh use smokeless tobacco (ST).Objective: To determine the outcome of maternal smokeless tobacco ingestion during pregnancy in delivery of preterm babies.Methods: A retrospective case control study was carried out in the department of Pediatrics & department of Obstetrics and Gynecology in Dhaka Medical College Hospital between July 2010 to June 2011. Immediately after admission, detailed history of the newborn baby & mother was taken. A total of 100 cases (preterm babies) and 100 suitably matched controls (sick term neonates) were enrolled. Every case satisfying the selection criteria (inclusion & exclusion criteria) was enrolled in the study. The mother was asked whether she used to use smokeless tobacco (jorda, shada or gul) during pregnancy and about frequency and duration of ingestion of ST.Results: Baseline characteristics of cases and controls were comparable. ST user mothers of preterm babies used ST about 5 times a day. Maternal smokeless tobacco (ST) use during pregnancy was significantly associated (46%) with the delivery of preterm babies (p<0.001) and carries a risk of 2.7 times than that of non ST users.Conclusion: Maternal ST use ?5 times a day during pregnancy increases 2.7 folds risk of delivery of preterm babies than that of non-ingested.Bangladesh J Child Health 2016; VOL 40 (3) :135-138

scholarly journals Brain Imaging Biomarkers for Chronic Pain

2022 ◽  
Vol 12 ◽  
Author(s):  
Zhengwu Zhang ◽  
Jennifer S. Gewandter ◽  
Paul Geha
Keyword(s):  
Chronic Pain ◽  
Brain Imaging ◽  
Substance Misuse ◽  
Clinical Applications ◽  
Imaging Biomarkers ◽  
Costs And Benefits ◽  
Brain Circuitry ◽  
Chronic Pain Conditions ◽  
The Brain

The prevalence of chronic pain has reached epidemic levels. In addition to personal suffering chronic pain is associated with psychiatric and medical co-morbidities, notably substance misuse, and a huge a societal cost amounting to hundreds of billions of dollars annually in medical cost, lost wages, and productivity. Chronic pain does not have a cure or quantitative diagnostic or prognostic tools. In this manuscript we provide evidence that this situation is about to change. We first start by summarizing our current understanding of the role of the brain in the pathogenesis of chronic pain. We particularly focus on the concept of learning in the emergence of chronic pain, and the implication of the limbic brain circuitry and dopaminergic signaling, which underly emotional learning and decision making, in this process. Next, we summarize data from our labs and from other groups on the latest brain imaging findings in different chronic pain conditions focusing on results with significant potential for translation into clinical applications. The gaps in the study of chronic pain and brain imaging are highlighted in throughout the overview. Finally, we conclude by discussing the costs and benefits of using brain biomarkers of chronic pain and compare to other potential markers.

scholarly journals Clinical Presentation of Dengue in 150 Admitted Cases in Dhaka Medical College Hospital

1970 ◽  
Vol 7 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Md Abul Kalam Azad ◽  
Hanif Mohammad ◽  
Md Billal Alam ◽  
Anup Kumar Saha ◽  
Tofayel Ahmed
Keyword(s):  
Dengue Fever ◽  
Prospective Observational Study ◽  
Health Hazard ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
Medical College Hospital ◽  
College Hospital ◽  
Medical College ◽  
Group 3 ◽  
Group 2

Dengue fever was not recognized as a major public health hazard in Bangladesh before 1999 outbreak, so there was little evidence and awareness in this regard. A prospective observational study was carried out to determine the risk group of patients suffering from dengue syndrome; clinical parameters of the subjects for hospitalization and the pattern of presentation of dengue fever in hospital care in different medicine units of Dhaka Medical College hospital from July 2000 to March 2001. Total 150 cases were selected randomly and diagnosed clinically as dengue, and were classified into 3 groups, i.e. 18 cases of classical dengue fever, 127 cases of dengue hemorrhagic fever (DHF-I and DHF-II) and 5 cases of dengue shock syndrome (DSS), and were discharged uneventfully. Among them 125(83.3%) were male and 25(16.7%) were female. Mean ages of the subjects were 26.75 ±3.69, 27.59 ± 1.18 and 10.67 ± 2.33 years in respective groups. Mean temperature was 103.45±0.28, 103.08±0.13, and 104.00±1.00 °F with mean duration was 5.50±0.51 days, 6.12±0.2 days, and 5.00±1.15 in respective groups. Majority had profound weakness, headache, myalgia, anorexia, nausea, and vomiting. Diarrhoea, abdominal pain, organomegaly, ascites, and pleural effusion were frequent complaints in group-3 patients, whereas infrequent complaints in other groups. Haemorrhagic manifestations were common in group 2 and 3 patients, melaena being the most common manifestations.   DOI = 10.3329/jom.v7i1.1355 J MEDICINE 2006; 7: 3-9

Sign in / Sign up

Export Citation Format

Share Document