scholarly journals Study of High Sensitive C-Reactive Protein in Ischemic Heart Disease

2013 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
BA Ferdous ◽  
N Sultana ◽  
S Ahmed ◽  
EH Khan ◽  
F Atia ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischaemic Heart Disease ◽  
Close Association ◽  
Ischemic Heart ◽  
C Reactive Protein ◽  
College Hospital ◽  
Medical College ◽  
Reactive Protein ◽  
Control Subjects

C-reactive protein (CRP) is a sensitive marker of inflammation, and elevated levels have been associated with future risk of myocardial infarction (MI). Even elevated CRP in healthy men and women can predict the future coronary events. This cross-sectional analytical study was undertaken to observe association between high hsCRP level with chronic ischaemic heart disease and was conducted in the Department of Biochemistry, Dhaka Medical College, Dhaka from July 2010 to June 2011. A total 50 cases were selected purposively according to the selection criteria form the patients admitted in the Department of Cardiology, Dhaka Medical College Hospital with chronic ischaemic heart disease (IHD). Diagnosed IHD patients were taken as cases; age- and sex-matched 50 healthy subjects were taken as controls. Serum hsCRP and serum TC, TAG, LDL-C and HDL-C were measured in all study subjects. The mean serum hsCRP concentration in cases and controls were 11.22±7.64 mg/dl and 1.72±0.98 mg/dl respectively. Serum hsCRP, Total Cholesterol, TAG and LDL-C were significantly higher in cases than control subjects. Serum HDL-C was significantly lower in cases than control subjects. The present study reveals that the patients of chronic ischemic heart disease have been found to have close association of increased level of hsCRP. DOI: http://dx.doi.org/10.3329/bjmb.v6i1.13281 Bangladesh J Med Biochem 2013; 6(1): 11-13

GENETICALLY ELLEVATED C-REACTIVE PROTEIN AND ISCHEMIC HEART DISEASE: THREE MENDELIAN RANDOMIZATION STUDIES

2008 ◽  
Vol 9 (1) ◽  
pp. 81
Author(s):  
J. Zacho ◽  
A. Tybjaerg-Hansen ◽  
J. SkovJensen ◽  
P. Grande ◽  
B.G. Nordestgaard
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Mendelian Randomization ◽  
Ischemic Heart ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Spectrum of heart diseases on Echocardiography in a Rural tertiary care Medical college hospital in Bangladesh

KYAMC Journal ◽  
2013 ◽  
Vol 3 (1) ◽  
pp. 223-234
Author(s):  
Md Saiful Islam ◽  
Md Annaz Mus Sakib ◽  
Ranjan Talukder ◽  
Sheikh Mohammed Taslim Yusuf
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Heart Diseases ◽  
Hypertensive Heart Disease ◽  
Medical College Hospital ◽  
Ischemic Heart ◽  
Cardiac Diseases ◽  
College Hospital ◽  
Medical College ◽  
Pericardial Diseases

Background: Echocardiography is a non-invasive, on-injurious, relatively cheap and useful   imaging technique for the evaluation of cardiac diseases. The procedure has reliable levels of  accuracy. Echocardiography commenced at the Cardiology Department of Khawja Yunus Ali   Medical College Hospital,Enayetpur Sirajgonj,Bangladesh since 2004.The aim of this study is to  report our experience with the procedure, and to define the clinical cases seen in our setting.Methods: This is a retrospective analysis of a prospectively collected data. Echocardiography was  performed using Aloka Prosound-SSD 5500 SV echocardiograph equipped with 2.5-5.0 MHz   transducer.  Results: During the period of 6 months under review (July 2011-December 2011), 1883 procedures  were performed. Those reports were reviewed for demographic parameter, indications for the procedure and the main echocardiographic diagnoses. The mean age of the 1883 individuals   studied was 50 +/- 18.67 years (10-90). There were 1221 men and 662 women. Four hundred   ninety eight(498) (26.45%) had Ischemic Heart Disease, 229(12.16%) subjects were Hypertensive Heart disease,160 subjects (8.5%) had rheumatic heart disease while 62,(3.3%) had   cardiomyopathy. Pericardial diseases, corpulmonale, congenital heart diseases, were present in 36(1.92%), 35 (1.85%), 88(4.67%), respectively. Seven hundred and Seventy Five (41.1%) subjects had normal study.   Conclusion: Ischemic heart disease was found to be the most prevalent cardiac condition in this study. The relatively frequent diagnoses of Hypertensive heart Disease, valvular heart disease, cardiomyopathies and pericardial diseases reflect the impact of infections on the cardiovascular   health of adult Bangladeshis. We suggest that prevention and treatment of cardiac diseases in our setting should among other things focus on life style modification, Ceasation of smoking,regular exercise, blood pressure and blood glucose control and early treatment of infections causing heart   diseases.DOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13657KYAMC Journal Vol. 3, No.-1, June 2012 p.223-224

scholarly journals C-Reactive Protein, Fibrin D-Dimer, and Incident Ischemic Heart Disease in the Speedwell Study

2001 ◽  
Vol 21 (4) ◽  
pp. 603-610 ◽  
Author(s):  
Gordon D. O. Lowe ◽  
John W. G. Yarnell ◽  
Ann Rumley ◽  
David Bainton ◽  
Peter M. Sweetnam
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
D Dimer

scholarly journals Elaboration of New Medical Technology for Predicting the Risk of Ischemic Heart Disease in the Workers of the Coal Industry

2019 ◽  
Vol 4 (3) ◽  
pp. 52-57 ◽  
Author(s):  
N. I. Panev ◽  
S. N. Filimonov ◽  
O. Yu. Korotenko ◽  
R. N. Panev ◽  
N. Ya. Paneva
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Genetic Markers ◽  
Medical Technology ◽  
Density Lipoprotein ◽  
Morphological Type ◽  
Coal Industry ◽  
Ischemic Heart ◽  
C Reactive Protein ◽  
Reactive Protein

Background. Ischemic heart disease is the leading cause of death in the majority of developed countries, including Russia. It determines the importance of elaboration of individual risk prediction of ischemic heart disease for primary prevention.Aim: to develop a strategy for predicting the ischemic heart disease in coal industry workers.Materials and methods. Ischemic heart disease incidence and its risk factors were studied in 196 coalmine workers (sinkers, stope miners). Rose Questionnaire, daily ECG monitoring and bicycle ergometry were used to detect angina. The indices of lipid metabolism, hemostatic system, the level of homocysteine, uric acid, C-reactive protein, constitutional-morphological type by Rees – Eysenck, genetic markers of blood groups of AB0, P and MN systems were studied.When elaborating the prognostic system, we used the Bayes method. A prognostic coefficient was calculated for each factor. Prediction of ischemic heart disease was carried out according to the sum of prognostic coefficients.Results. Ischemic heart disease was detected in 18 (9.2 %) miners. According to the above mentioned indices, a medical technology was elaborated to predict the ischemic heart disease, based on the determination of the most significant risk markers: age, work experience in harmful working conditions, type A behavior, arterial hypertension, fasting hyperglycemia, metabolic syndrome, hypercholesterolemia, decrease in the level of high density lipoprotein cholesterol, increase in the value of low density lipoprotein cholesterol, hypertriglyceridemia, hyperhomocysteinemia, hyperfibrinogenemia, increase in the level of soluble fibrin monomer complexes and C-reactive protein, abdominal obesity, hypersthenic constitutional-morphological type by Rees – Eysenck, genetic markers of blood groups of AB0, P and MN systems.Conclusion. Based on the most significant markers, a personalized strategy for ischemic heart disease prediction in miners was elaborated, which allowed timely undertaking therapeutic and preventive measures.

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