scholarly journals Detection of CTX-M gene in extended spectrum beta lactamase (ESBL) producing Escherichia coli and Klebsiella species of different hospitals.

2012 ◽  
Vol 4 (2) ◽  
pp. 28-31 ◽  
Author(s):  
Nawshad Muhammad Wahidur Rahman ◽  
Afzalunnessa Binte Lutfor ◽  
Sanya Tahmina Jhora ◽  
Mahmuda Yasmin ◽  
Jalaluddin Ashraful Haq
Keyword(s):  
Escherichia Coli ◽  
Tertiary Care ◽  
Beta Lactamase ◽  
M Gene ◽  
Klebsiella Species ◽  
Extended Spectrum Beta Lactamase ◽  
Extended Spectrum ◽  
Synergy Test ◽  
Tertiary Care Hospitals ◽  
Klebsiella Spp

A total of 200, non-duplicate ESBL producing strains (171 Escherichia coli and 29 Klebsiella spp.) from three tertiary care hospitals were detected using screening test & double disc synergy test. All isolates were screened for the detection of CTX-M type Extended spectrum Beta-lactamase (ESBL) using PCR. Among them 133 (66.5%) were positive for CTX-M type ESBLs which include 114 (66.66%) E.coli and 19 (65.51%) Klebsiella spp. This is the first report of identifying CTX-M gene in ESBL producing Escherichia coli and Klebsiella species of different hospitals.DOI: http://dx.doi.org/10.3329/bjmm.v4i2.10829 

Fecal Carriage of Extended Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli and Klebsiella spp. in Children in Zonguldak

2019 ◽  
Vol 24 (3) ◽  
pp. 236-243
Author(s):  
Nesibe Söğütlü ◽  
Füsun Cömert ◽  
İbrahim Etem Pişkin ◽  
Elif Aktaş ◽  
Füruzan Köktürk ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Beta Lactamase ◽  
Extended Spectrum Beta Lactamase ◽  
Fecal Carriage ◽  
Extended Spectrum ◽  
Klebsiella Spp

Wide dissemination of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella spp. in acute care and rehabilitation hospitals

2011 ◽  
Vol 140 (3) ◽  
pp. 528-534 ◽  
Author(s):  
A. KOHLENBERG ◽  
F. SCHWAB ◽  
H. RÜDEN
Keyword(s):  
Escherichia Coli ◽  
Control Measures ◽  
Beta Lactamase ◽  
Extended Spectrum Beta Lactamase ◽  
Extended Spectrum ◽  
The Mean ◽  
Rehabilitation Hospitals ◽  
Klebsiella Spp ◽  
Wide Dissemination ◽  
Community Onset

SUMMARYA prospective surveillance system for extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-E) and ESBL-producing Klebsiella spp. (ESBL-K) was implemented in 39 German hospitals with the aim of determining the incidence densities (IDs) of community-onset and hospital-onset cases and of identifying risk factors for high IDs of hospital-onset cases. During 2008, 2081 ESBL-E/K cases were documented. ESBL-E cases (n=1330, 63·9%) were more common than ESBL-K cases (n=751, 36·1%), but a higher proportion of ESBL-K cases (59%) than of ESBL-E cases (39·5%) were hospital-onset cases. The mean IDs were 0·54 (range 0–2·53) per 1000 patient-days for all ESBL-EK cases, 0·29 (range 0–1·81) per 1000 patient-days for community-onset ESBL-EK cases and 0·25 (range 0–1·82) per 1000 patient-days for hospital-onset ESBL-EK cases. Regression analysis showed a linear association between the IDs of community-onset and hospital-onset cases. The wide dissemination of ESBL-E and ESBL-K emphasizes the need for hospital-wide surveillance to guide control measures.

scholarly journals Antimicrobial Susceptibility Pattern and Detection of Extended-Spectrum Beta-Lactamase (blaCTX-M) Gene in Escherichia coli from Urinary Tract Infections at the University Teaching Hospital in Lusaka, Zambia

2020 ◽  
Author(s):  
Emmanuel Chirwa ◽  
Georgina Mulundu ◽  
Kunda Ndashe ◽  
Kalo Kanongesha ◽  
Kaziwe Simpokolwe ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Antimicrobial Susceptibility ◽  
University Teaching ◽  
Beta Lactamase ◽  
M Gene ◽  
Extended Spectrum Beta Lactamase ◽  
Extended Spectrum ◽  
Tract Infections ◽  
The University

Urinary tract infections caused by Extended Spectrum Beta-Lactamase producing Escherichia coli are increasing globally and yet treatment still remains a challenge due to antibiotic resistance of the causative agent. The aim of the study was to determine the antimicrobial susceptibility pattern and detect the presence of blaCTX-M gene in Escherichia coli isolated from urinary tract infection patients at the University Teaching Hospital, Lusaka, Zambia. This was a cross-sectional study that involved the collection of urine samples from patients who were diagnosed with urinary tract infections. The samples were cultured on MacConkey agar complemented with cefotaxime and Polymerase Chain Reaction was performed to confirm the Extended-Spectrum Beta-Lactamase producers by detecting the CTX-M gene. Antimicrobial susceptibility tests were conducted using standard methods. A total of 327 urine samples were cultured and 15 (4.6%) of these samples were positive ESBL producers. The isolates showed complete resistance to ampicillin and cotrimoxazole. Multi drug-resistant Extended Spectrum Beta-Lactamase producing Escherichia coli was detected in 4.6 % of UTI patients at the University Teaching Hospital.

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