scholarly journals Factors Affecting Therapeutic Compliance among the Patients with Rheumatic Heart Disease in Bangladesh

2018 ◽  
Vol 10 (2) ◽  
pp. 180-185 ◽  
Author(s):  
Kakon Farzana ◽  
Mohammad Omar Faruque ◽  
Salma Zareen ◽  
Kamrun Nahar Choudhury ◽  
Ahmed Hossain

Background: Acute rheumatic fever (ARF) can recur as a result of subsequent Group A Streptococcus (GAS) infections and each recurrence can worsen Rheumatic heart disease (RHD) that has evoked a substantial disease burden in developing countries, including Bangladesh. The objective of this study was to determine the penicillin compliance for rheumatic fever patients.Methods: A matched cross sectional study was conducted among 160 patients in National Center for the Control of Rheumatic Fever and Heart Diseases (NCCRF/HD), Dhaka. Data was collected on face-to-face interview using a standard structured questionnaire about socio-demographic, clinical and behavioral factors. Descriptive and multivariate logistic regression analyses were used to analyze the data.Results: The multiple logistic regression analyses indicated that duration of diagnosis>5 beyond the duration of diagnosis <5 years (OR=2.484, CI=1.170-5.421), age (OR=0.548,CI=0.217-0.574), sex (OR=0.916, CI=0.422-1.964), education (OR=1.963, CI= 0.737-05.361), marital status(OR=0.700, CI=0.272-1.774), fathers education (OR=0.482 CI=0.176 -1.279) and family member (OR= 0.619 CI= 0.2 97 -1.261) were significantly or almost significantly associated with RHD status.Conclusion: In this study, the identified risk groups for rheumatic heart disease reflect a complex interaction between socioeconomic conditions and chronic disease status. Interventions focused on education and poverty will undoubtedly be useful, but not sufficient. Rheumatic heart disease control would benefit from a collaboration of broad public health activities aimed at the prevention and control other chronic diseases. The integration of rheumatic heart disease control activities with non communicable disease programme is crucial in Bangladesh.Cardiovasc. j. 2018; 10(2): 180-185

2021 ◽  
Vol 8 ◽  
Author(s):  
Renato Pedro de Almeida Torres ◽  
Rômulo Francisco de Almeida Torres ◽  
Gabrielle de Crombrugghe ◽  
Scarllet Palacin Moraes da Silva ◽  
Sarah Leticia Veroneze Cordeiro ◽  
...  

Secondary prophylaxis of rheumatic heart diseases is efficient in reducing disease recurrence, heart damage, and cardiac impairment. We aimed to monitor the clinical evolution of a large Brazilian cohort of rheumatic patients under prolonged secondary prophylaxis. From 1986 to 2018, a cohort of 593 patients with rheumatic fever was followed every 6 months by the Reference Center for the Control and Prevention of Rheumatic Fever and Rheumatic Cardiopathy (CPCFR), Paraná, Brazil. In this cohort, 243 (41%) patients did not present cardiac damage (group I), while 350 (59%) were diagnosed with rheumatic heart disease (RHD) (group II) using the latest case definition. Among group II, 233 and 15 patients had impairment of the mitral and aortic valves, respectively, while 102 patients had impairment of both valves. Lesions on the mitral and aortic valves presented a regression in 69.9 and 48.7% of the patients, respectively. Active patient recruitment in the reference center and early detection of oropharyngeal GAS were important factors for optimal adherence to the prophylactic treatment. Patients with disease progression were associated with noncompliance to secondary prophylaxis. No patients undergoing regular prophylaxis presented progression of the rheumatic cardiac disease. Eighteen valvular surgeries were performed, and four (0.7%) patients died. This study confirmed that tailored and active efforts invested in rheumatic heart disease secondary prevention allowed for significant clinical improvement.


2018 ◽  
Vol 10 (2) ◽  
pp. 206-211 ◽  
Author(s):  
Mohammad Arifur Rahman ◽  
Afzalur Rahman ◽  
Syed Nasir Uddin ◽  
AKM Monwarul Islam ◽  
Tariq Ahmed Chowdhury ◽  
...  

In the 21st century, Rheumatic fever (RF) and Rheumatic heart disease (RHD) are neglected diseases of marginalized communities. Globally, RHD remains the most-common cardiovascular disease in young people aged <25 years. Although RF and RHD have been almost eradicated in areas with established economies, migration from low-income to high-income settings might be responsible for a new burden of RHD in high-income countries. Globally, the prevalence of rheumatic fever (RF) and rheumatic heart disease (RHD) has declined sharply but, in developing countries, RF is still aleading cause of heart disease and, consequently, death in children and young adults. In 2005, it was estimated that over 2.4 million children aged 5-14 years were having RHD globally and 79% of all these cases were from lessdeveloped countries.Cardiovasc. j. 2018; 10(2): 206-211


Author(s):  
Madhavi Sarkari ◽  
Mithilesh Yadav ◽  
Ashutosh Kr. Rai

Background: The incidence and prevalence rates of heart failure (HF) are increasing worldwide. The prevalence of HF rises exponentially with increasing age and affects 4% to 8% of people older than 65. The leading causes of HF in India include coronary artery disease (CAD), diabetes, hypertension, rheumatic valvular heart diseases and primary cardiac muscle diseases. Rheumatic heart disease (RHD) is still a common cause of HF in India. Epidemiological studies have estimated that 1.5% to 2% population experience HF and it is the main reason for hospital admission of elderly patients. The objective of this study was to establish the etiological factors of heart failureMethods: A cross sectional study of 150 patients above the age of 18 years presented with heart failure diagnosed clinically on the basis of Framingham heart failure criteria and echocardiography, done over a period of one year in department of medicine in BRD medical college Gorakhpur Uttar Pradesh.Results: A total of 150 patients were include in this analysis the majority of patients were male (57.3%). Age of patients ranged from 18 - 70 years and 84% patients were above the age of 40 years.Conclusions: Heart failure was more prevalent in elderly male above 40 years of age. Myocardial infarction, DCMP, rheumatic heart disease and hypertensive heart failure are the common etiology leading to heart failure.


2000 ◽  
Vol 6 (2-3) ◽  
pp. 437-446
Author(s):  
A. Bassili ◽  
S. R. Zaher ◽  
A. Zaki ◽  
G. Tognoni

A cross-sectional study was conducted in specialist children’s hospitals in Alexandria, which aimed to evaluate the current regimen of secondary prophylaxis for children suffering from rheumatic heart disease. Two-thirds of the patients had complied with their prophylactic regimen. Prophylactic failure occurred in one-third of the patients, raising doubts about the efficacy of the brands of penicillin prescribed. Recurrence of rheumatic fever was recorded in 37.3% of the patients, with semiurban or rural residence and non-compliance with secondary prophylaxis the significant risk factors. These unsatisfactory findings suggest the need for a more effective strategy of primary and secondary prophylaxis for controlling rheumatic fever in our community


2020 ◽  
Vol 9 (15) ◽  
Author(s):  
Emmy Okello ◽  
Emma Ndagire ◽  
Jenifer Atala ◽  
Asha C. Bowen ◽  
Marc P. DiFazio ◽  
...  

Background Despite the high burden of rheumatic heart disease in sub‐Saharan Africa, diagnosis with acute rheumatic fever (ARF) is exceedingly rare. Here, we report the results of the first prospective epidemiologic survey to diagnose and characterize ARF at the community level in Africa. Methods and Results A cross‐sectional study was conducted in Lira, Uganda, to inform the design of a broader epidemiologic survey. Key messages were distributed in the community, and children aged 3 to 17 years were included if they had either (1) fever and joint pain, (2) suspicion of carditis, or (3) suspicion of chorea, with ARF diagnoses made by the 2015 Jones Criteria. Over 6 months, 201 children met criteria for participation, with a median age of 11 years (interquartile range, 6.5) and 103 (51%) female. At final diagnosis, 51 children (25%) had definite ARF, 11 (6%) had possible ARF, 2 (1%) had rheumatic heart disease without evidence of ARF, 78 (39%) had a known alternative diagnosis (10 influenza, 62 malaria, 2 sickle cell crises, 2 typhoid fever, 2 congenital heart disease), and 59 (30%) had an unknown alternative diagnosis. Conclusions ARF persists within rheumatic heart disease–endemic communities in Africa, despite the low rates reported in the literature. Early data collection has enabled refinement of our study design to best capture the incidence of ARF and to answer important questions on community sensitization, healthcare worker and teacher education, and simplified diagnostics for low‐resource areas. This study also generated data to support further exploration of the relationship between malaria and ARF diagnosis in rheumatic heart disease/malaria‐endemic countries.


BMJ ◽  
1964 ◽  
Vol 2 (5412) ◽  
pp. 775-779 ◽  
Author(s):  
T. D. Dublin ◽  
A. D. Bernanke ◽  
E. L. Pitt ◽  
B. F. Massell ◽  
F. H. Allen ◽  
...  

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