Childhood Stroke: A Cross-sectional Study in a Tertiary Level Hospital of Bangladesh

Background & objective:The present study was undertaken to find the prevalence and pattern of childhood stroke and to see its clinical presentation and sub-types. Materials & Methods:The present cross sectional study was conducted in the Department of Pediatrics, BSMMU, Dhaka over a period of 6 months. A total of 30 children suffering from childhood stroke, provisionally diagnosed on the basis of clinical criteria and confirmed by neuroimaging were the study population.The demographic variables were age, sex, age at onset and age at case taking. The signs and symptoms at presentation, causes, investigations, neuro-imaging findings and final diagnosis were recorded. Result: Over half (53.4%) of the patients were in the range of 13 – 36 months with mean age of the patients being 39.1 ± 8.2 months. The mean age at onset was 36.2 ± 8.3 months. About 47% of patients were male and 53% female. Paresis of limb was invariably present, unconsciousness at onset (50%), convulsion (33.3%), aphasia (26.7%), raised blood pressure (23.3%), vomiting (13.3%), visual defect (8.7%) and headache (6.7%). Arterial occlusion was the main cause of childhood stroke (36.7%) followed by hypertensive encephalopathy (10%), migraine, hematoligical disease, cardiomyopathies (each 6.7%). Investigations revealed that over one-third (36.7%) of the patients had leucocytosis and 13.3% abnormal echocardiography. All the children either exhibited ischemia or infarction or hemorrhage on Computed Tomography (CT) and 86.7% on Magnetic Resonance Imaging (MRI). Seventy percent and 36.7% of patients had MRA and MRV abnormality respectively. About 47% of the patients had acute ischemic stroke, 13.3% AIS with left-sided haemiparesis with facial palsey and another 13.3% AIS with right-sided haemiparesia. Acute haemorragic stroke (AHS), acute stroke with Hb beta-thalassaemia, acute stroke with right-sided haemiparesis with cardiomyopathy and recurrent haemorragic stroke were rare. Conclusion: The study concluded that childhood stroke occurs most frequently between one to three years of age and equally affects male and female. Paresis of limb and unconsciousness at the onset were the main presenting features and arterial hypertension and hypertensive encephalopathy were the common cause of childhood stroke. Nearly three-quarters of the children present with ischemic stroke and the rest with haemorrhagic stroke. Ibrahim Card Med J 2016; 6 (1&2): 20-24

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A cross-sectional study of awareness regarding dog bite and its management in rural community of Maharashtra, India

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20203593 ◽

2020 ◽

Vol 7 (9) ◽

pp. 1307

Author(s):

Mohammed Alqwaifly

Keyword(s):

Saudi Arabia ◽

Ischemic Stroke ◽

Acute Stroke ◽

Acute Ischemic Stroke ◽

Stroke Care ◽

Cross Sectional Study ◽

Sectional Study ◽

Acute Stroke Care ◽

Cross Sectional ◽

Stroke Treatment

Background: Stroke is a major cause of morbidity and disability worldwide. However, its outcomes have improved in the last few years with advancement in acute stroke treatment, including the use of tissue plasminogen activator (t-PA) within 4.5 hours of onset, which led several international guidelines to adopt it as the standard of care. In this study, authors sought to assess the knowledge, practices, and attitudes of emergency and medicine staff in Qassim, Saudi Arabia toward acute ischemic stroke care.Methods: A quantitative observational cross-sectional study involving 148 physicians from emergency and medicine departments (only three neurologists) was conducted in three main hospitals of the Qassim region, Saudi Arabia. Information was obtained from a self-administered questionnaire. A logistic regression model was used to control for potential confounding factors.Results: Ninety-two percent of participants were aware of t-PA. Eighty-seven percent of participants thought that t-PA was an effective treatment for acute ischemic stroke. Only 20% of participants had given t-PA or participated in the use of t-PA in acute ischemic stroke. Moreover, 64% of participants believed that allowing blood pressure to remain high was the most appropriate action in the first 24 hours in acute ischemic stroke patients who presented outside the t-PA window.Conclusion: Most of the emergency and medicine staff are well informed about t-PA, but the majority of these physicians have never given t-PA or participated in the administration of t-PA to a stroke patient. The main finding here is the positive outlook among emergency and medicine physicians in Qassim toward training in acute stroke care and administering t-PA for stroke, which will positively impact patient outcomes.

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Pattern of Stroke in Diabetic and Non-Diabetic Patients Admitted at a Tertiary Care Hospital, a Cross Sectional Study

Journal of Clinical Case Reports and Studies ◽

10.31579/2690-8808/073 ◽

2021 ◽

Vol 2 (5) ◽

pp. 01-05

Author(s):

Mubashir Ahmed ◽

Sohail Ahmed Siddiqui ◽

Abdul Haq ◽

Atif Ahmed ◽

Pir Abdul Hayee ◽

...

Keyword(s):

Ischemic Stroke ◽

Acute Stroke ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Haemorrhagic Stroke ◽

Cross Sectional Study ◽

Care Hospital ◽

Sectional Study ◽

Stroke Patients ◽

Cross Sectional

Objective: To determine the frequency of diabetic among stroke patients and to compare the pattern of stroke in diabetic and non-diabetic stroke patients admitted at a tertiary care hospital in Hyderabad, Sindh. Methods: A cross sectional study enrolled 148 consecutive adult acute stroke patients admitted at Liaquat University Hospital, Hyderabad, during Sep 2014 to Feb 2015. Demographic, clinical, radio-imaging and laboratory data were collected on structured questionnaire to identify diabetes, type of stroke and different risk factors of stroke. Data was entered and analysed by using SPSS version 16. Association was seen by using Pearson’s Chi-square test and Independent t test. A P value of < 0.05 was considered statistically significant. Results: A total of 148 acute stroke cases were enrolled in the study. Males were 92 (62%). Mean age of study participants was 51.21 ± 10.19 years. Diabetes was found in 104 (70.3%) stroke patients. Ischemic stroke was seen in 101 (68.2%) and haemorrhagic stroke seen in 47 (31.8) stroke patients. Diabetes was more common in ischemic stroke 81 (80.2) as compared to haemorrhagic stroke 23 (48.9%) (P< 0.05). Hospital mortality of stroke patients was 37 (25%). No difference of mortality in diabetic and non-diabetic (P>0.05) stroke patients was recorded. Conclusion: Diabetes was found in majority of stroke patients. Ischemic stroke was more common than haemorrhagic stroke. Ischaemic stroke is more prevalent in diabetic whereas haemorrhagic stroke was more in non-diabetic stroke patients. Prognosis of stroke was bad in both diabetic and non-diabetic stroke patients.

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Combined effect of hypertension and hyperuricemia on ischemic stroke in a rural Chinese population

BMC Public Health ◽

10.1186/s12889-021-10858-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Peng Sun ◽

Mengqi Chen ◽

Xiaofan Guo ◽

Zhao Li ◽

Ying Zhou ◽

...

Keyword(s):

Ischemic Stroke ◽

Missing Data ◽

Chinese Population ◽

Joint Effect ◽

Cross Sectional Study ◽

Combined Effect ◽

Sectional Study ◽

Cross Sectional ◽

Current Smoking ◽

Positive Correlations

Abstract Background To investigate the combined effect of hypertension and hyperuricemia to the risk of ischemic stroke in a rural Chinese population. Methods The cross-sectional study was conducted from 2012 to 2013 in a rural area of China. After exclusion for missing data, we finally included 11,731 participants into analysis. Results After adjusting for age, current smoking, current drinking, BMI, TG, HDL-C and eGFR, hypertension was significantly associated with ischemic stroke in men (OR: 2.783, 95% CI: 1.793, 4.320) and in women (OR: 4.800, 95% CI: 2.945, 7.822). However, hyperuricemia was significantly associated with ischemic stroke only in women (OR: 1.888, 95% CI: 1.244, 2.864). After full adjustment, participants with both hypertension and hyperuricemia had 8.9 times higher risk than those without them. Finally, the interaction between hypertension and hyperuricemia was statistically significant only in women rather than in men after full adjustment. Conclusions This study demonstrated the positive correlations between hypertension, hyperuricemia and ischemic stroke. Our study also demonstrated the joint effect between hypertension and hyperuricemia towards ischemic stroke only in women, not in men.

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Gender Differences in the Age-Stratified Prevalence of Risk Factors in Korean Ischemic Stroke Patients: A Nationwide Stroke Registry-Based Cross-Sectional Study

International Journal of Stroke ◽

10.1111/ijs.12146 ◽

2013 ◽

Vol 9 (6) ◽

pp. 759-765 ◽

Cited By ~ 20

Author(s):

Tai Hwan Park ◽

Youngchai Ko ◽

Soo Joo Lee ◽

Kyung Bok Lee ◽

Jun Lee ◽

...

Keyword(s):

Risk Factors ◽

Gender Differences ◽

Ischemic Stroke ◽

Cross Sectional Study ◽

Sectional Study ◽

Stroke Patients ◽

Cross Sectional ◽

Stroke Registry

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Admixture analysis of age at onset in older patients with schizophrenia spectrum disorders

International Psychogeriatrics ◽

10.1017/s104161022000085x ◽

2020 ◽

Vol 32 (6) ◽

pp. 781-785

Author(s):

Maureen M. J. Smeets-Janssen ◽

Idan M. Aderka ◽

Paul D. Meesters ◽

Sjors Lange ◽

Sigfried Schouws ◽

...

Keyword(s):

Late Onset ◽

Age At Onset ◽

Cross Sectional Study ◽

Data Driven ◽

Admixture Analysis ◽

Schizophrenia Spectrum Disorders ◽

Sectional Study ◽

Cross Sectional ◽

Schizophrenia Spectrum ◽

Spectrum Disorders

ABSTRACTThe nature of schizophrenia spectrum disorders with an onset in middle or late adulthood remains controversial. The aim of our study was to determine in patients aged 60 and older if clinically relevant subtypes based on age at onset can be distinguished, using admixture analysis, a data-driven technique. We conducted a cross-sectional study in 94 patients aged 60 and older with a diagnosis of schizophrenia or schizoaffective disorder. Admixture analysis was used to determine if the distribution of age at onset in this cohort was consistent with one or more populations of origin and to determine cut-offs for age at onset groups, if more than one population could be identified. Results showed that admixture analysis based on age at onset demonstrated only one normally distributed population. Our results suggest that in older schizophrenia patients, early- and late-onset ages form a continuum.

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Variables Associated with Attitude Towards Medication and Compliance of Treatment in Outpatients with Stable Schizophrenia

European Psychiatry ◽

10.1016/s0924-9338(11)73092-9 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 1387-1387

Author(s):

E. Valmisa ◽

J. Galan

Keyword(s):

Statistical Analysis ◽

Adverse Events ◽

Cross Sectional Study ◽

Antipsychotic Treatment ◽

Sectional Study ◽

Subjective Effect ◽

Cross Sectional ◽

General Attitude ◽

Clinical Criteria ◽

Length Of Treatment

IntroductionAttitude towards medication has been associated with compliance, but different variables have been associated with them.PurposeAssess relationship between attitude towards medication and compliance, and to evaluate variables related to treatment associated with them.MethodsNon-interventional, multicentre, cross-sectional study. Outpatients with stable schizophrenia (according to clinical criteria) who had the last acute episode at least 2 months before were included.Results941 patients recruited were included in the study, 931 patients were included in the statistical analysis.Mean score on DAI was 4.2 and in its subscales: 1.6 on general attitude 2.8 on subjective effect 2.8. Mean score on compliance (a component of David's scale of insight), with range from 0 to 4, was: 3.0.There were statistically significant (p < 0.0001) correlations between this subscale of David's insight scale and total DAI score (r = 0.495), with general attitude (r = 0.480) and with subjective effect (r = 0.419).Variables related to medication with association statistically (p < 0.005) with DAI (total score and both subscales) were: length of treatment with current antipsychotic, number of total adverse events (AEs), moderate AEs, severe AEs, and total severity of adverse events (sum of severity of each one). All of them, except number of severe AEs, had statistically significant relationship (p < 0.05) with compliance.ConclusionVariables related to attitude towards medication (DAI total and both subscale) were very similar to those related to compliance (construct of David's insight scale). Adverse events and length of antipsychotic treatment had a clear clinical relevance. Study sponsored by AstraZeneca Spain, S.A.

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Association between Family Histories of Thyroid Cancer and Thyroid Cancer Incidence: A Cross-Sectional Study Using the Korean Genome and Epidemiology Study Data

Genes ◽

10.3390/genes11091039 ◽

2020 ◽

Vol 11 (9) ◽

pp. 1039

Author(s):

Soo-Hwan Byun ◽

Chanyang Min ◽

Hyo-Geun Choi ◽

Seok-Jin Hong

Keyword(s):

Thyroid Cancer ◽

Family History ◽

Cancer Incidence ◽

Age At Onset ◽

Cross Sectional Study ◽

Sectional Study ◽

Epidemiology Study ◽

Cross Sectional ◽

Family Histories ◽

Thyroid Cancer Incidence

This study assessed the association between thyroid cancer and family history. This cross-sectional study used epidemiological data from the Korean Genome and Epidemiology Study from 2001 to 2013. Among 211,708 participants, 988 were in the thyroid cancer group and 199,588 were in the control group. Trained interviewers questioned the participants to obtain their thyroid cancer history and age at onset. The participants were examined according to their age, sex, monthly household income, obesity, smoking, alcohol consumption, and past medical history. The adjusted odds ratios (95% confidence intervals) for the family histories of fathers, mothers, and siblings were 6.59 (2.05–21.21), 4.76 (2.59–8.74), and 9.53 (6.92–13.11), respectively, and were significant. The results for the subgroup analyses according to sex were consistent. The rate of family histories of thyroid cancer for fathers and siblings were not different according to the thyroid cancer onset, while that of mothers were higher in participants with a younger age at onset (<50 years old group, 11/523 [2.1%], p = 0.007). This study demonstrated that thyroid cancer incidence was associated with thyroid cancer family history. This supports regular examination of individuals with a family history of thyroid cancer to prevent disease progression and ensure early management.

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