scholarly journals A Case Report : Pregnancy with Multiple Sclerosis

2020 ◽  
Vol 9 (1-2) ◽  
pp. 93-95
Author(s):  
Shiuly Chowdhury ◽  
Nilufar Islam ◽  
Khadiza Nurun Nahar ◽  
Kaniz Fatema ◽  
Salma Akter Munmun ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Young Adults ◽  
Case Report ◽  
Pregnant Woman ◽  
Postpartum Period ◽  
Clinical Course ◽  
Child Bearing ◽  
Pregnancy And Postpartum ◽  
Do So

Multiple sclerosis causes disability in young adults and like most autoimmune diseases, affects women more commonly in their child-bearing years. In general, pregnancy does not appear to affect the long-term clinical course of multiple sclerosis and the disease does not affect the course or outcome of pregnancy. In this reportedcase, a pregnant woman with multiple sclerosis showed relapse of the disease in first half of her pregnancy and disease was well controlled in the second half of her pregnancy and postpartum period after taking appropriate measure. Women who have multiple sclerosis and wish to have a family can usually do so successfully with the assistance of their neurologist and obstetrician. Ibrahim Card Med J 2019; 9 (1&2): 93-95

Mild gray matter atrophy in patients with long-standing multiple sclerosis and favorable clinical course

2021 ◽  
pp. 135245852110196
Author(s):  
Rosa Cortese ◽  
Marco Battaglini ◽  
Francesca Parodi ◽  
Maria Laura Stromillo ◽  
Emilio Portaccio ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Gray Matter ◽  
Clinical Course ◽  
Resonance Imaging ◽  
Volume Changes ◽  
Magnetic Resonance Imaging Mri ◽  
Global Brain ◽  
Diffuse Brain

The mechanisms responsible for the favorable clinical course in multiple sclerosis (MS) remain unclear. In this longitudinal study, we assessed whether magnetic resonance imaging (MRI)-based changes in focal and diffuse brain damage are associated with a long-term favorable MS diseases course. We found that global brain and gray matter (GM) atrophy changes were milder in MS patients with long-standing disease (⩾30 years from onset) and favorable (no/minimal disability) clinical course than in sex-age-matched disable MS patients, independently of lesions accumulation. Data showed that different trajectories of volume changes, as reflected by mild GM atrophy, may characterize patients with long-term favorable evolution.

Concealed pregnancies and protected postpartum periods

2020 ◽  
pp. 472-492
Author(s):  
Jan Brunson
Keyword(s):  
Maternal Health ◽  
Sexual Activity ◽  
Postpartum Period ◽  
Urban Community ◽  
Demographic And Health Survey ◽  
Ethnographic Interviews ◽  
Critical Junctures ◽  
Pregnancy And Postpartum ◽  
Nutritional Needs

This chapter analyses the delineation of what counts as a critical period for action and intervention in improving maternal health. Using ethnographic interviews alongside descriptive data from the Nepal Demographic and Health Survey, it analyses two critical junctures for maternal health, the antepartum and postpartum periods, in the context of a particular peri-urban community of Nepal. The postpartum period is socially recognized as sutkeri for Hindu Nepalis, a forty-day period in which a woman who gave birth is considered ritually polluted, but also particularly susceptible to long-term health problems if proper care is not taken for her body in its vulnerable state. This perception of bodily vulnerability and mandated care while sutkeri exists in stark contrast to the absence of such notions and protective practices for the period of pregnancy. Pregnancy, an outwardly visible sign of sexual activity, is a state that one should hide or minimize in order to maintain one’s reputation and honour as a woman. Women worked to conceal their pregnancies, and typically no or little extra care was provided to women to meet their nutritional needs or to enable them to avoid hard physical labour. However, intersecting statuses, such as caste and class, and contexts, such as agricultural households and multi-generational households, crosscut any simple characterizations of the pregnancy and postpartum periods—even within the confines of a subgroup of the Nepali population (Parbatiya) in a single community and place.

scholarly journals Hypertensive Complications of Pregnancy and Risk of Venous Thromboembolism

Hypertension ◽  
2020 ◽  
Vol 75 (3) ◽  
pp. 781-787
Author(s):  
Luuk J.J. Scheres ◽  
Willem M. Lijfering ◽  
Norbert F.M. Groenewegen ◽  
Sanne Koole ◽  
Christianne J.M. de Groot ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Postpartum Period ◽  
Reference Group ◽  
Later Life ◽  
Thrombotic Risk ◽  
Hazard Ratios ◽  
Anticoagulation Clinics ◽  
Pregnancy And Postpartum ◽  
Cox Proportional Hazard Models

Hypertension during pregnancy and preeclampsia are associated with increased arterial thrombotic risk in later life. Whether these complications are associated with risk of venous thromboembolism (VTE) on the short term after pregnancy and on the long term, that is, outside pregnancy, is largely unknown. We conducted a nationwide cohort study in women with at least 1 pregnancy and their first VTE risk by linking the Dutch perinatal registry (Perined) to anticoagulation clinics. We used Cox proportional hazard models to estimate hazard ratios (HRs) and corresponding 95% CI for VTE risk in women with hypertension during pregnancy, women with preeclampsia, compared with women with uncomplicated pregnancies (reference). A total of 1 919 918 women were followed for a median of 13.7 (interquartile range, 7.6–19.2) years for a total of 24 531 118 person-years in which 5759 first VTEs occurred; incidence rate: 2.3 (95% CI, 2.3–2.4) per 10 000 person-years. In the first pregnancy and 3-month postpartum period, VTE risk was higher in women with hypertension, HR, 2.0 (95% CI, 1.7–2.4), and highest among women with preeclampsia, HR, 7.8 (95% CI, 5.4–11.3), versus the reference group. On the long term, women with hypertension during pregnancy and preeclampsia had a higher VTE risk: HR, 1.5 (95% CI, 1.4–1.6) and HR, 2.1 (95% CI, 1.8–2.4), respectively, versus the reference group. When excluding events during pregnancy and postpartum, these HRs were 1.4 (95% CI, 1.3–1.5) and 1.6 (95% CI, 1.4–2.0), respectively. In conclusion, hypertension during pregnancy and preeclampsia are associated with an increased VTE risk during pregnancy and postpartum period and in the 13 years after.

scholarly journals R u a smkn m0m?: Aspects of a Text Messaging Smoking Cessation/Reduction Intervention for Younger Mothers

2013 ◽  
Vol 10 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Sophie Soklaridis ◽  
Jenna López ◽  
Karina Czyzewski ◽  
Rosa Dragonetti ◽  
Peter Selby
Keyword(s):  
Smoking Cessation ◽  
Focus Groups ◽  
Young Women ◽  
Postpartum Period ◽  
Text Messaging ◽  
Unmet Need ◽  
Postpartum Women ◽  
Telephone Interviews ◽  
Pregnancy And Postpartum

Introduction: Women who are younger in age are more likely to smoke during pregnancy and postpartum and tend to have less success with cessation/reduction. There is an unmet need for interventions targeted to pregnant and postpartum young women that provide them with support to quit/reduce long-term into the postpartum period and beyond.Aims: Our study aimed to gain an in-depth understanding of the perspectives of young pregnant and postpartum women of text messaging (TM) as a conduit for smoking cessation/reduction, and to determine the appropriate content, frequency, duration and unique features needed for an effective cessation/reduction TM programme.Methods: Six focus groups and six telephone interviews were convened with 36 pregnant and postpartum women 16–30 years of age.Results: Three main themes were identified: 1) topic areas that women would like TM to focus on; 2) the need for messages to be tailored; and 3) the importance for the programme to take a woman-centered approach.Conclusions: Respondents supported the idea of a TM cessation/reduction intervention and had clear programme recommendations. A personalised, woman-centered TM programme that meets a young woman's unique needs and addresses her concerns through her participation and direction is likely to empower and support her to quit/reduce.

scholarly journals Case Report: Clinical and Imaging Characteristics of a Patient with Anti-flotillin Autoantibodies: Neuromyelitis Optica or Multiple Sclerosis?

2021 ◽  
Vol 12 ◽  
Author(s):  
Ke Shang ◽  
Chang Cheng ◽  
Chuan Qin ◽  
Jun Xiao ◽  
Gang Deng ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Report ◽  
Neuromyelitis Optica ◽  
Clinical Reasoning ◽  
Clinical Course ◽  
Case Summary ◽  
First Case ◽  
Imaging Characteristics

BackgroundDemyelination diseases are complex puzzles that are not always straightforward to diagnose. Multiple sclerosis and neuromyelitis optica are two that are frequently encountered. Numerous autoantibodies newly discovered in recent years have significantly aided clinical reasoning and diagnosis in differentiating demyelination disorders. Here we report a case of demyelination disease with anti-flotillin autoantibodies positive, which is not common in past references.Case summaryThe patient presented with characteristic neuromyelitis optica symptoms and had remission and relapse. But his images exhibited characteristics of both neuromyelitis optica spectrum illness and multiple sclerosis.ConclusionThis is the first case report describing the clinical course and imaging characteristics of demyelination illness associated with anti-flotillin autoantibodies. Although so far it appears to be a subtype of multiple sclerosis, there is still a potential that it is separate from MS and NMOSD.

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