scholarly journals Human Papilloma Virus Vaccine for Cervical Cancer Prevention

2021 ◽  
Vol 39 (2) ◽  
pp. 123-131
Author(s):  
Chowdhury Shamima Sultana
Keyword(s):  
Public Health ◽  
Cervical Cancer ◽  
Screening Program ◽  
Hpv Vaccination ◽  
Invasive Cervical Cancer ◽  
Public Health Problem ◽  
Developed Countries ◽  
Hpv Infection ◽  
Human Papilloma Virus Vaccine ◽  
Major Public Health Problem

HPV infection is estimated to be responsible for about 5% of human cancers worldwide. Among all HPV-associated malignancies, cervical cancer is the most important cause of morbidity and mortality worldwide. Cervical cancer is the fourth most common cancer in women worldwide and leading cause of cancer death among females in less developed countries. Persistent HPV infection is a necessary cause of invasive cervical cancer with a prevalence of 99.7% in cervical cancer worldwide.At least 70% of cervical cancers are caused by HPV 16 and HPV 18. HPV vaccination in combination with regular screening offers the most effective way for women to be protected against cervical cancer.The global burden of cervical cancer falls heaviest on the developing countries which haven’t introduced the HPV vaccine as part of their national public health strategy to prevent and control cervical cancer. Different studies showed a drop in the prevalence of HPV associated diseases in vaccinated populations. Sustained efficacy, immunogenicity, and safety of the bHPV vaccine were observed in the final analysis of a follow-up study up to 9.4 years postvaccination. Cervical cancer is a major public health problem in Bangladesh. There has been little success with screening program against cervical cancer in Bangladesh. Therefore, a National HPV Vaccination Program seems to be the window of opportunity to reduce the mortality and morbidity of cervical cancer in Bangladesh. J Bangladesh Coll Phys Surg 2021; 39(2): 123-131

scholarly journals Cervical cancer in Iquitos, Peru: local realities to guide prevention planning

2004 ◽  
Vol 20 (1) ◽  
pp. 160-171 ◽  
Author(s):  
Jennifer L. Hunter
Keyword(s):  
Cervical Cancer ◽  
Screening Program ◽  
Public Health Problem ◽  
Ethnographic Study ◽  
Herbal Remedies ◽  
Pap Smears ◽  
Major Public Health Problem ◽  
Medical Systems ◽  
Cervical Cancer Screening Program ◽  
Cancer Experience

Cervical cancer is a major public health problem in Latin America, and in much of the underdeveloped world. This issue has not historically been addressed as a health priority, but in recent years is receiving increased attention and funding. This ethnographic study on the experience of cervical cancer was conducted in Iquitos, Peru, between August 1998 and May 1999. Research methodologies included: (1) observation and household interviews to obtain background knowledge about the region, medical systems, and local cultural understanding of illness; (2) cancer experience interviews; and (3) case studies of women in various stages of cervical cancer or diagnosis. Findings are presented related to local knowledge and experience of Pap smears and cervical cancer and the ineffectiveness of a recently initiated cervical cancer screening program. The findings guide recommendations for interventions in the region in relation to: (1) needed changes in health education, (2) screening frequency and age, (3) sites for screening and treatment, (4) type and availability of treatment, (5) payment issues, (6) documentation of care, and (7) the potential of herbal remedies.

Cervical neoplasia

2019 ◽  
pp. 357-364
Keyword(s):  
Cervical Cancer ◽  
Screening Program ◽  
Cervical Screening ◽  
Hpv Vaccination ◽  
Invasive Cervical Cancer ◽  
Intraepithelial Neoplasia ◽  
Cervical Neoplasia ◽  
Women Living With Hiv ◽  
The Bethesda System ◽  
Common Malignancy

Cervical neoplasia provides an overview of the 4th most common malignancy in women worldwide, including the premalignant phase. Specific terminology used in cytology and histology (including atypia, dyskaryosis, cervical intraepithelial neoplasia (CIN), cervical glandular intraepithelial neoplasia (CGIN) and invasive cervical cancer (ICC) are explained, and the epidemiology and risk factors (with an emphasis on human papilloma virus (HPV)) for this common malignancy are included. Clinical presentation is outlined. Cervical screening is discussed, including the role of HPV testing, and both the British Association for Cytopathology/NHS cervical screening program 2013 classification of cervical cytology and the Bethesda system (used more widely worldwide) are explained. Diagnosis includes colposcopic examination of the cervix, and the management of both CIN and cervical cancer are included. HPV vaccination, pregnancy, and women living with HIV (including ICC as AIDS-defining) are discussed.

scholarly journals Smoking in Latin America: a major public health problem

1998 ◽  
Vol 14 (suppl 3) ◽  
pp. S109-S115 ◽  
Author(s):  
Vera Luiza da Costa e Silva ◽  
Sergio Koifman
Keyword(s):  
Public Health ◽  
Latin America ◽  
Latin American ◽  
Health Problem ◽  
Public Health Problem ◽  
Lung Cancer Mortality ◽  
Developed Countries ◽  
Major Public Health Problem ◽  
Tobacco Epidemic ◽  
Latin American Countries

Smoking has become a major public health problem in Latin America, and its scope varies from country to country. Despite difficulties in obtaining methodologically consistent data for the region, we analyzed the results from prevalence surveys in 14 Latin American countries. Smoking prevalence among men varied from 24.1% (Paraguay) to 66.3% (Dominican Republic) and among women from 5.5% (Paraguay) to 26,6% (Uruguay). By applying point prevalence data to the stage model of the tobacco epidemic in developed countries, we concluded that the Latin American countries are in stage 2, i.e., with a clearly rising prevalence among men, a prevalence for women that is beginning to increase, and mortality attributable to smoking among men still not reflecting peak prevalence. None of the countries analyzed appeared to have reached stage 3, in which one observes a downward trend in prevalence of smoking among men and peak prevalence among women, with broad impact on tobacco-related mortality. The only exception appears to be Paraguay, which is still emerging from stage 1, i.e., with low prevalence rates among men, too. Nevertheless, high lung cancer mortality rates in Uruguay and Argentina are comparable to those of the developed countries.

scholarly journals O enfermeiro na assistência à mulher com câncer de colo uterino

2015 ◽  
pp. 19
Author(s):  
Carla Monteiro Santos ◽  
Doralice De Almeida Nascimento Silva ◽  
Gleise Gonçalves Passos da Silva ◽  
Tatiana Santana de Oliveira ◽  
Luiz Faustino dos Santos Maia
Keyword(s):  
Public Health ◽  
Health Care ◽  
Cervical Cancer ◽  
Health Problem ◽  
Public Health Problem ◽  
Morbidity And Mortality ◽  
Major Public Health Problem ◽  
Care Practices ◽  
Multiple Health

O Câncer de Colo Uterino apresenta nos dias atuais um grande problema de saúde pública no Brasil, necessitando cada vez mais de profissionais capacitados para o combate a essa doença maligna, minimizando sua morbimortalidade. Neste âmbito podemos destacar o Papel do enfermeiro como fundamental na transformação dessa realidade que vivemos hoje. O enfermeiro atua tanto no sentido de assistir, coordenar as práticas de cuidado, quanto no sentido de educar, promover, proteger, reabilitar essas mulheres, de forma autônoma, criativa e ativa nos múltiplos níveis de atenção à saúde, através do levantamento de hipóteses analíticas e intervenções sistematizadas de rotinas de cuidados, subsidiando falhas e promovendo continuidade e resolutividade do cuidado em saúde.Descritores: Câncer de Colo Uterino, Mulher, Enfermagem. Nurses in care woman with cervical cancerAbstract: The Cancer Cervical presents nowadays a major public health problem in Brazil, requiring more and more trained professionals to combat this evil disease, minimizing morbidity and mortality. In this context we can highlight the nurse's role as fundamental in transforming this reality we live in today. The nurse acts both to assist coordinate care practices, as to educate, promote, protect, rehabilitate these women in an autonomous, creative and active in multiple health care levels, through the lifting of analytical assumptions systematized and interventions care routines, subsidizing failure and promoting continuity and resolution of health care. Descriptors: Cervical Cancer, Women, Nursing. Enfermero en la atención la mujer con cáncer de cuello uterinoResumen: Los regalos del cáncer de cuello uterino hoy en día un importante problema de salud pública en Brasil, lo que requiere cada vez más capacitados profesionales para combatir esta enfermedad mal, lo que minimiza la morbilidad y la mortalidad. En este contexto cabe destacar el papel de la enfermera tan fundamental en la transformación de esta realidad que vivimos hoy. La enfermera actúa tanto para ayudar, coordinar las prácticas de atención, como para educar, promover, proteger, rehabilitar a estas mujeres en un autónomas, creativas y activas en múltiples niveles de atención de salud, a través de la elevación de supuestos analíticos rutinas sistematizados y las intervenciones de atención, subsidiando el fracaso y la promoción de la continuidad y de la resolución de la atención sanitaria. Descriptores: Cáncer de Cuello Uterino, Mujer, Enfermería.

scholarly journals Molecular Genetic Diagnostic Strategy to Help Clinicians to a Better Assessment of the Heaviness of a Human Papilloma Virus (HPV) Infection

2011 ◽  
Vol 4 ◽  
pp. IDRT.S6646
Author(s):  
Florian Heirler ◽  
Emanuel Ždárský ◽  
Ricardo Borelli ◽  
Hans Jürgen Heppner
Keyword(s):  
Cervical Cancer ◽  
Screening Program ◽  
Molecular Genetic ◽  
Lymphocyte Transformation ◽  
Developed Countries ◽  
Hpv Infection ◽  
Cancer Development ◽  
Carrier Status ◽  
Diagnostic Strategy ◽  
Cytological Examination

Since the introduction of a cytology-based screening program for cervical cancer in developed countries a dramatic reduction of specific morbidity and mortality has been reported. In addition to this in 1972 zur Hausen proposed HPV as a causal factor of cervical cancer. About 15 viral subtypes have been identified: the so called high-risk subtypes for cancer development. Despite this the clinical use of subtype identification in a prevention strategy has not substantially been reported. Simple identification of HPV carrier status cannot reliably be used as a prognostic factor for cervical cancer development nor as a useful alternative to cytological examination. Therefore we are establishing a link between the classical cytological examination and the techniques of molecular biology. Our strategy detects HPV in a semi-quantitative way as well as the E7-m-RNA activity and T-lymphocyte-transformation in order to better calculate how serious an infection is, how active the virus and how active the defense reaction is.

HUMAN PAPILLOMAVIRUS INFECTION AND CERVICAL CANCER (OWERWIEW)

2021 ◽  
Vol 2 (4) ◽  
pp. 23-29
Author(s):  
I.P. Sharipova ◽  
◽  
E.I. Musabaev ◽  
Keyword(s):  
Cervical Cancer ◽  
Viral Infections ◽  
Cervical Screening ◽  
Public Health Problem ◽  
Hpv Infection ◽  
Geographic Region ◽  
Screening Methods ◽  
Major Public Health Problem ◽  
Oncogenic Viruses ◽  
Screening Programs

Viral infections are responsible for 15–20% of all human cancers. Infection with oncogenic viruses can contribute to various stages of carcinogenesis. Despite effective screening methods, cervical cancer continues to be a major public health problem. There are large differences in morbidity and mortality from cervical cancer by geographic region. The age-specific prevalence of HPV varies widely in different populations and has shown two peaks of HPV positiveness in young and older women. Around the world, there have been many studies on the epidemiology of HPV infection and oncogenic properties due to different HPV genotypes. However, there are still many countries where population prevalence has not yet been determined. Moreover, screening strategies for cervical cancer differ from country to country. Organized cervical screening programs are potentially more effectivethan opportunistic screening programs.Key words:Human papillomavirus, cervical cancer, screening, dysplasia

Study of antibiotics resistance in bacteria isolated from retailed eggshell in three major markets in Minna, Nigeria

2020 ◽  
pp. 3709-3719
Author(s):  
N.U. Adabara ◽  
C.E. Amarachi ◽  
A.S. Adedeji ◽  
A. Usman ◽  
M. Maude ◽  
...  
Keyword(s):  
Public Health ◽  
Public Health Problem ◽  
Developed Countries ◽  
Multidrug Resistant ◽  
Total Coliform ◽  
Health Concern ◽  
Resistant Bacteria ◽  
Antibiotics Resistance ◽  
Major Public Health Problem ◽  
Antibiotic Susceptibility Test

Food borne disease associated with inappropriately treated or untreated eggs is a major public health problem affecting developing and developed countries. This study isolated, identified and determined the Antibiogram of bacteria isolates from eggshell of eggs obtained from three major markets in Minna, Nigeria. A total of ten (10) duplicate egg samples were purchased from egg retailers. The egg samples were analyzed for the enumeration and isolation of bacteria. The isolated bacteria were identified using biochemical methods. Antibiotic susceptibility test to prescribed commercially available antibiotic discs was also investigated. The total viable bacteria count (TVBC) ranged from 1.38×104 - 2.52×104 cfu/mL while the total coliform count (TCC) ranged from 8.5×103 - 2.02×104 cfu/mL. Escherichia coli (9.1%), Streptococcus pyogenes (4.5%), Enterococcus sp. (4.5%), Shigella sp. (13.6%), Salmonella sp. (13.6%), Staphylococcus aureus (36.4%), Clostridium sp. (9.1%) and Neisseria sp. (9.1%) were isolated and identified from eggshells. Gram positive bacteria showed highest sensitivity to gentamycin (100%) however, resist cloxacillin, ceftadizime and erythromycin (100%). Similarly, there was no ciprofloxacin resistant Gram-negative bacteria though E. coli, Salmonella sp. and Shigella sp. isolated from eggshells were resistant to augmentin and amoxicillin. Further analysis of result revealed that all the isolated bacteria from eggshells were multidrug resistant except Neisseria sp. with multidrug resistant index greater than 0.2. The fact that these antibiotic resistant bacteria can be transferred to humans is of public health concern. Therefore, stringent use of public health regulations for cleaning eggs before retailing is advocated.

scholarly journals O enfermeiro na assistência à mulher com câncer de colo uterino

2015 ◽  
Vol 5 (14) ◽  
pp. 19
Author(s):  
Carla Monteiro Santos ◽  
Doralice De Almeida Nascimento Silva ◽  
Gleise Gonçalves Passos da Silva ◽  
Tatiana Santana de Oliveira ◽  
Luiz Faustino dos Santos Maia
Keyword(s):  
Public Health ◽  
Health Care ◽  
Cervical Cancer ◽  
Health Problem ◽  
Public Health Problem ◽  
Morbidity And Mortality ◽  
Major Public Health Problem ◽  
Care Practices ◽  
Multiple Health

O Câncer de Colo Uterino apresenta nos dias atuais um grande problema de saúde pública no Brasil, necessitando cada vez mais de profissionais capacitados para o combate a essa doença maligna, minimizando sua morbimortalidade. Neste âmbito podemos destacar o Papel do enfermeiro como fundamental na transformação dessa realidade que vivemos hoje. O enfermeiro atua tanto no sentido de assistir, coordenar as práticas de cuidado, quanto no sentido de educar, promover, proteger, reabilitar essas mulheres, de forma autônoma, criativa e ativa nos múltiplos níveis de atenção à saúde, através do levantamento de hipóteses analíticas e intervenções sistematizadas de rotinas de cuidados, subsidiando falhas e promovendo continuidade e resolutividade do cuidado em saúde.Descritores: Câncer de Colo Uterino, Mulher, Enfermagem. Nurses in care woman with cervical cancerAbstract: The Cancer Cervical presents nowadays a major public health problem in Brazil, requiring more and more trained professionals to combat this evil disease, minimizing morbidity and mortality. In this context we can highlight the nurse's role as fundamental in transforming this reality we live in today. The nurse acts both to assist coordinate care practices, as to educate, promote, protect, rehabilitate these women in an autonomous, creative and active in multiple health care levels, through the lifting of analytical assumptions systematized and interventions care routines, subsidizing failure and promoting continuity and resolution of health care. Descriptors: Cervical Cancer, Women, Nursing. Enfermero en la atención la mujer con cáncer de cuello uterinoResumen: Los regalos del cáncer de cuello uterino hoy en día un importante problema de salud pública en Brasil, lo que requiere cada vez más capacitados profesionales para combatir esta enfermedad mal, lo que minimiza la morbilidad y la mortalidad. En este contexto cabe destacar el papel de la enfermera tan fundamental en la transformación de esta realidad que vivimos hoy. La enfermera actúa tanto para ayudar, coordinar las prácticas de atención, como para educar, promover, proteger, rehabilitar a estas mujeres en un autónomas, creativas y activas en múltiples niveles de atención de salud, a través de la elevación de supuestos analíticos rutinas sistematizados y las intervenciones de atención, subsidiando el fracaso y la promoción de la continuidad y de la resolución de la atención sanitaria. Descriptores: Cáncer de Cuello Uterino, Mujer, Enfermería.

scholarly journals 973Eliminating Cervical Cancer in the Asia Pacific- From Research to Policy and Practice

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Sharon Hanley
Keyword(s):  
Public Health ◽  
Cervical Cancer ◽  
Cervical Screening ◽  
Hpv Vaccination ◽  
Scale Up ◽  
Public Health Problem ◽  
Associate Professor ◽  
Asia Pacific ◽  
Vaccine Hesitancy ◽  
Research Fellow

Abstract Focus and outcomes for participants Rationale for the symposium, including for its inclusion in the Congress Cervical cancer, caused by persistent infection with oncogenic human papillomavirus (HPV), is one of the most preventable and treatable forms of cancer, yet more than 300,000 women die from the disease annually and over 500,000 cases are diagnosed. Modelling has shown that effective integration of HPV immunization programmes, HPV-based screening, and access to high-quality cancer treatment and palliative care services has the potential to eliminate cervical cancer in most countries in the world over the next century. In 2018, the Director-General of WHO made a global call to action for the elimination of cervical cancer as a public health problem. As a result, WHO has developed a global strategy towards eliminating cervical cancer as a public health problem due for endorsement at the World Health Assembly in May 2020, which proposes an elimination threshold of four cases per 100 000 women and includes 2030 triple-intervention coverage targets for scale-up of HPV vaccination of 90%, twice-lifetime cervical screening of 70%, and treatment of pre-invasive lesions and invasive cancer of 90%. As the first country to establish a national HPV immunization programme and one of the first countries to move to an HPV based screening programme, Australia has played a leading role in the global battle against cervical cancer and is on course to eliminate the disease within the next decade. However, while the burden of disease and the highest mortality from cervical cancer occur in lower income countries, factors such as the inequitable cervical cancer burden in Indigenous populations and vaccine hesitancy mean that significant barriers to the elimination of cervical cancer also exists within high-income countries. This session will have seven experts working in four countries within the Asia Pacific region. By sharing experiences and providing evidence-based guidance on key technical and strategic issues, we hope to generate a comprehensive understanding and new knowledge on factors impacting participation in, and the potential for effective scale up of, cervical cancer control programmes within the region. Presentation program Names of presenters -Dr Kate Simms is a Postdoctoral Research Fellow at Cancer Council NSW, Australia. Her research focusses on modelling the impact of HPV vaccination and cervical cancer screening across a range of settings, including predictions for the potential elimination of cervical cancer across 181 countries. -Associate Professor Julia Brotherton is a public health physician and Medical Director of VCS Population Health. She is involved in research and policy development informing the implementation and evaluation of HPV vaccination programs in Australia and is member of the WHO Director General's Expert Advisory Group on Cervical Cancer Elimination. -Assistant Professor Sharon Hanley is a cancer epidemiologist at Hokkaido University, Japan. Her research interests include HPV vaccine hesitancy and HPV self-sampling to increase cervical screening uptake in never/under screened Japanese women. - Associate Professor Lisa Whop is an Indigenous Senior Research Fellow at the Australian National University, Canberra, Australia. Her research focuses on improving health outcomes for Aboriginal and Torres Strait Islander people with cancer, with a key focus on equity. - Dr Megan Smith is a Postdoctoral Research Fellow whose research focuses on optimizing and successfully implementing cervical cancer prevention, at the population level and in different population subgroups. She has contributed to a large number of reports to government, including several evaluations that have directly informed policy in Australia, New Zealand and England. -Professor Andrew Vallely is a clinical epidemiologist at the Kirby Institute, University of New South Wales, Australia. He recently completed a field evaluation comparing point-of-care Xpert HPV testing using self-collected specimens with visual inspection of the cervix with acetic acid (VIA), to detect high-grade cervical disease. - Professor Woo Yin Ling is a Consultant Obstetrician and Gynaecologist at the University of Malaya. She is the programme designer of Project ROSE (Removal of Obstacles to Cervical Screening), a novel cervical screening research programme which employs HPV self-sampling and digital technology to increase access to cervical screening in Malaysia. Names of facilitator or chair Assistant Professor Sharon J.B. Hanley, Hokkaido University and Professor John Kaldor, Kirby Institute, University of New South Wales?

Sign in / Sign up

Export Citation Format

Share Document