scholarly journals Effect of Peanut (Arachis Hypogaea L.) on Dyslipidemia in Young Adult

2015 ◽  
Vol 10 (1) ◽  
pp. 11-16
Author(s):  
Hasina Akter ◽  
Nasim Jahan ◽  
Nayma Sultana

Background: Dyslipidemia is a major risk factor for cardiovascular disease. Lipid lowering drugs are available in modern medicine but prolong use of these drugs may produce some side effects. Peanut due to some of its active component can improve lipid profile.Objective: To observe the effects of peanut (Arachis hypogaea L.) on dyslipidemia in young adults.Methods: This prospective interventional study was carried out in the Department of Physiology, Sir Salimullah Medical College (SSMC), Dhaka between 1st July 2013 and 30th June 2014. For this purpose 30 dyslipidemic young adults of both sexes with aged 30 to 40 years were included in this study and they were selected from Out Patient Department of Medicine of Sir Salimullah Medical College and Mitford Hospital, Dhaka. They were studied three times i,e before supplementation with peanut (BSP), after 4 weeks supplementation with peanut (4 wks AP) and after 8 weeks supplementation with peanut (8 wks AP). For assessing lipid profile TAG, LDL-C, TC and HDL-C of all subjects were estimated by enzymatic method. The statistical analysis was done by using paired sample‘t’ test as applicable.Results: In this study, the mean serum TAG, LDL-C and TC levels were significantly decreased after 8 weeks supplementation with peanut in comparison to those of after 4 weeks and before supplementation with peanut. However, these levels were also decreased after 4 weeks supplementation than those of before supplementation but it was significant only for TC (p<0.05) and LDL-C (p<0.001). Whereas, the mean serum HDL-C level was significantly (p<0.001) increased after 8 weeks supplementation when compared to those of after 4 weeks and before supplementation of peanut.Conclusion: The present study revealed that, peanut (Arachis hypogaea L.) has effect on improvement of lipid profile by lowering serum TAG, LDL-C, TC levels and by increasing serum HDL-C level. This lipid lowering effects of peanut may be due to its high Mg+2 content and other active components of peanut.Bangladesh Soc Physiol. 2015, June; 10(1): 11-16

1990 ◽  
Vol 17 (2) ◽  
pp. 65-67 ◽  
Author(s):  
T. B. Brenneman ◽  
W. D. Branch ◽  
A. S. Csinos

Abstract The susceptibility of 16 peanut (Arachis hypogaea L.) genotypes (eight Virginia and eight runner types) to southern stem rot (Sclerotium rolfsii Sacc.) was evaluated in field tests over three years. Mean disease incidence for all cultivars was 10.0, 15.4 and 16.4 disease loci per 12.2 m row and average yields were 3488, 2826 and 3569 kg/ha in 1986, 1987 and 1988, respectively. Disease incidence averaged 14.3 disease loci per 12.2 m of row for both market types. The mean yield for the eight Virginia types was 3287 kg/ha versus 3214 for the eight runner types. Culitvars within market types varied significantly in disease incidence and pod yield. Of the Virginia types, NC 6 and Florigiant were the most susceptible with NC 9, VA 81B and Early Bunch being the most resistant. Incidence of stem rot in runner cultivars was high except for Southern Runner and Langley which had about 50% less disease than the most susceptible entries. There was a highly significant correlation (P≤0.01) between yields and disease incidence all three years. Overall, Southern Runner had the lowest disease incidence and highest pod yield of any cultivar. Compared to Florunner, the current industry standard for runner types, Southern Runner had about 50% less disease and yields were 1346 kg/ha higher.


2002 ◽  
Vol 37 (9) ◽  
pp. 953-956 ◽  
Author(s):  
Jim M. Backes ◽  
Patrick M. Moriarty ◽  
Cheryl A. Gibson

Although numerous studies have established the efficacy of micronized fenofibrate (MF) and gemfibrozil in improving lipid profiles, there are limited comparative data on the lipid-lowering effects of these two agents. The objective of this study was to evaluate the mean changes in lipid values of hypertriglyceridemic patients crossed over from gemfibrozil to MF. The Medical charts of 21 patients were analyzed retrospectively. Patients were maintained on gemfibrozil 600 mg twice daily for a minimum of 3 months. The patient's last fasting lipid profile on gemfibrozil was compared to the first lipid profile after crossover to MF 200 to 201 mg/day. Patients were excluded if there were alterations in other lipid-lowering therapy during the cross-over or documented non-adherence. The lipid profiles after the crossover showed a significant reduction in triglycerides (56%; P < 0.05) and TC/HDL ratio (38%; P < 0.05) and a significant increase in HDL (22%; P < 0.05). There were nonsignificant changes in other lipid values: TC (-22%; P = 0.058), LDL (+5%; P = 0.866) and LDL/HDL ratio (+6; P = 1.0). The results show that MF had additional favorable effects on triglycerides, HDL, and TC/HDL ratio compared with gemfibrozil. A larger, randomized trial to confirm these effects is warranted.


1961 ◽  
Vol 12 (2) ◽  
pp. 239 ◽  
Author(s):  
K Helms ◽  
NE Grylls ◽  
GS Purss

A disease of peanut (Arachis hypogaea L.) in Queensland, previously referred to as "chlorosis", was identified as being caused by the tomato spotted wilt virus. Symptoms of the disease on peanut are described. Erigeron bonariensis L., Tagetes minuta L., and Trifolium subterraneurn L. are recorded as new hosts. The disease was not seed-transmitted, although seeds developed lesions and were malformed. Infective virus was found in tissues of the integuments of immature seed. The maximum disease incidence recorded in an individual crop was 5.5%. The mean seed yield of diseased plants was 12.7 g per plant, whereas that of healthy plants was 128.2 g.


Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Paulo A Lotufo ◽  
Steven Jones ◽  
Michael Blaha ◽  
Cid Sabbag ◽  
Raul Dias-Santos ◽  
...  

Introduction: Psoriasis is associated with chronically heightened systemic inflammatory tone and increased risk for cardiovascular disease. It remains to be established if the psoriatic state itself associates with dyslipidemia. Hypothesis: The lipid profile of patients with psoriasis is more atherogenic compared to disease-free control patients. Methods: The concentration and size of lipoprotein particles were measured using nuclear magnetic resonance spectroscopy in 221 patients with a diagnosis of psoriasis (53.6% men; mean age=56.6 years; mild cases=31%; moderate/severe only skin=27%; arthritis=27%)) and 689 disease-free persons matched by sex and age. We compared means of lipoprotein particle concentration and size using a univariate general linear model and adjusting for body-mass index, waist circumference, diabetes, use of lipid lowering-drugs, as well as duration/severity of psoriasis. Results: Patients with psoriasis were more overweight, had larger waist circumference, and a higher frequency of diabetes and use of lipid-lowering drugs. Total LDL particle means (nmol/L) for the psoriasis and control groups were 1436 (1378-1494) vs. 1420 (1388-1452) (P=0.4), respectively. The mean concentration of IDL was higher in patients with psoriasis compared to controls: 143.6 (130.7-156.5) vs. 106.1 (99.1-113.2), P<0.01. Large and small LDL particle concentrations were similar between groups. Large VLDL/chylomicron particle concentrations (nmol/L) were higher in psoriasis patients compared to controls 6.1 (5.2-7.0) vs. 4.0 (3.6-4.5) (P<0.01). Total HDL particle and subfractions were not statistically different between groups. The mean size (nm) of VLDL was higher in psoriasis patients: 50.2 (49.2-51.2) vs. 46.2 (45.6-46.7) (P<0.001) for psoriasis and controls, respectively. In contrast, mean sizes of LDL and HDL particles were similar (P=0.3). Adjustment for covariates above mentioned did not change these findings. The absence/presence of arthritis did not change the results. Conclusion: Patients with psoriasis have a more atherogenic lipid profile compared to controls with higher levels of IDL and VLDL of large and small size. In addition, the greater mean size of VLDL particles in psoriasis compared to controls suggests enhanced secretion of triglyceride loaded VLDL, impaired lipolysis and impaired clearance of remnant IDL.


2013 ◽  
Vol 2 (1) ◽  
pp. 14-20
Author(s):  
Samaresh Chandra Hazra ◽  
Ehsanul Kabir ◽  
Nafiza Ahmed

Background: Doxepin hydrochloride is a dibenzoxepin tricyclic, has a potent H1 & H2 receptor blocking actions. If topical doxepin can effectively control pruritus associated with eczematous dermatoses, we can use it as adjunctive therapy and can reduce the drawbacks of topical steroids and antihistamines. Methods: An interventional study from january 2010 to june 2010 has done in the department of dermatology and venereology, Faridpur Medical College Hospital, Bangladesh to evaluate the efficacy of topical doxepin cream in eczematous dermatoses. We included moderate to severe pruritic eczematous dermatoses patient in this study. Results: Improvement of pruritus was assessed at day 3 and at day 7 by both Visual analogue scale (VAS) and Itch severity scale (ISS). At day 3 by VAS 61.3 %( 57) patients showed improvement and at day 7 improvement rate increases to 84.9% (79). By ISS improvement at day 3 was 68.9% (64) and increased to 90.3% (84) at day 7. Improvement was experienced by all types of eczema patients. An average of 27.27% (29.88% by VAS and 24.65% by ISS) reduction of pruritus noticed at the end of day 3 and at the end of study, response increases to 55.58% (57.10% by VAS and 54.06% by ISS). Paired sample t test was done both for visual analogue scale (VAS) and itch severity scale (ISS) that compare the mean pruritus reduction at day 3 and day 7 with baseline pruritus (day-0). Pruritus reduction was statistically significant at day 3 and day 7 both by VAS & ISS.Conclusion: Doxepin cream is highly effective in relieving pruritus associated with eczematous dermatoses but it has little effect on eczema itself.DOI: http://dx.doi.org/10.3329/updcj.v2i1.13955 Update Dent. Coll. j: 2012; 2 (1): 14-20


1983 ◽  
Vol 10 (2) ◽  
pp. 66-69 ◽  
Author(s):  
C. C. Green ◽  
M. K. Beute ◽  
J. C. Wynne

Abstract Three methods presently used to evaluate disease resistance in peanut (Arachis hypogaea L.) to Cylindrocladium black rot (CBR) were compared to identify the most efficient method to screen peanut lines in field tests. Forty randomly selected F2 families in the F5 generation from a cross of the CBR-resistant source NC 3033 with NC 6 and the two parents were evaluated for percent dead and diseased plants, root rot index and microsclerotia/g of root. Significant differences were detected between the parents (p = 0.05) and among segregates (familes) (p = 0.01) for percent dead and diseased plants only. Error components exceeded the mean square values for differences among segregates for the root rot index and microsclerotia/g of root resulting in no significant differences among entries for these traits and low to no correlations among traits. Percent dead and diseased plants was concluded to be the best of the three methods for screening peanut lines in the field for CBR resistance.


2020 ◽  
Vol 22 (4) ◽  
pp. 238-242
Author(s):  
Sanita Kayastha ◽  
B Tiwari ◽  
R Subedi

The main objective of the study was to see the association of dyslipidemia in preeclampsia (PET) as compare to normotensive (NT) patients. It was a descriptive study done in Nepal Medical College Teaching Hospital Department of Obstetrics and Gynecology from April 2019 from April 2020. A total of 75 PET (test group) and 75 NT (control group) in their third trimester were included. Their fasting lipid profile was studied. It was found that triglyceride (TG) and very low density lipoprotein (VLDL) was significantly high among PET group as compared to that of NT patients. The mean TG of PET group was 266.11± 98.61 and the NT group was 187±58.56 (p=0.00) and the mean VLDL of PET group was 46.00±15.31 and NT group was 37.88±12.85 (p=0.001). On the other hand, the total cholesterol (TC), low density lipoprotein (LDL) and high density lipoprotein (HDL) were not significantly different in both the groups. It was also found that with the severity of the disease (Preeclampsia), the level of TG and VLDL increased significantly. Therefore, among the investigation done for PET, we should include lipid profile, especially the TG and VLDL. Furthermore, TG and VLDL should be measured serially (at least once a week) so as to predict the progress of PET and manage the patient accordingly.


Author(s):  
Naila Ikram ◽  
Shehzada A. A. Babar ◽  
Tahir Aslam ◽  
Hira Malik ◽  
Natasha Zahid ◽  
...  

<p class="abstract"><strong>Background:</strong> The association of cholecystectomy with alterations in lipid profile is well documented. Objectives of this study were to determine the effect of cholecystectomy on lipid profile of cholelithiasis patients.</p><p class="abstract"><strong>Methods:</strong> This cross-sectional observational study was done on 170 patients admitted in general surgery department of Naz Memorial Hospital, Karachi from July 2018 to June 2019. Symptomatic cholelithaisis patients between 18 to 60 years, elective cholecystectomy was included while patients previously on lipid lowering agents, diagnosed renal failure, nephrotic syndrome, cardiac failure, pregnant mothers, hypothyroidism, pancreatitis and obstructive jaundice were excluded. For data analysis, SPSS was used. Wilcoxon signed ranked test was used to compare mean values of pre and post-operative lipid profiles after cholecystectomy keeping p value of &lt;0.05 as significant.  </p><p class="abstract"><strong>Results:</strong> 60% of patients were females with majority, 31% patients between 31-40 years while least, i.e. 11% were between 61-70 years. The mean pre-operative and post-operative difference of 52±7.32 mg/dl was seen in total cholesterol levels (p&lt;0.001). The mean difference in high density lipoprotein (HDL) between pre and post-operative was of 13±0.36 mg/dl (p&lt;0.001). The mean difference in low density lipoprotein (LDL) between pre- and post-operative was 61±10.45 mg/dl (p&lt;0.001). The mean difference in triglycerides levels between pre- and post-operative was 46±25.49 mg/dl (p&lt;0.001).</p><p class="abstract"><strong>Conclusions:</strong> Cholecystectomy in gall stone disease patients elicited favorable response in significantly lowering levels of total serum cholesterol, LDL and triglycerides while substantially increasing levels of HDL cholesterol.</p><p> </p>


2013 ◽  
Vol 3 (1) ◽  
pp. 3-6
Author(s):  
II Mannan ◽  
SH Khundkar ◽  
T Ahmed ◽  
FB Ibrahim

The subcutaneous pedicled rhomboid flap is a technique that can release scar contractures without skin graft or additional flap. This study was planned to evaluate the efficacy of this technique. This prospective interventional study was conducted in the department of Plastic Surgery, Dhaka Medical College Hospital, over a period of 16 months. A total of 28 procedures of subcutaneous pedicled rhomboid flap were performed on 12 patients. The contractures were released successfully by the rhomboid flaps. The mean percentage gain in length of the scar band was 77.28%. Most of the cases had complication free recovery. The clinical results indicated that the subcutaneous pedicled rhomboid flap is an effective and versatile technique for releasing scar contractures in different parts of the body. DOI: http://dx.doi.org/10.3329/bdjps.v3i1.14998 Bangladesh Journal of Plastic Surgery 2012, 3(1): 3-6


2016 ◽  
Vol 5 (08) ◽  
pp. 4759
Author(s):  
Binod Mahato

Cardiovascular disease is one of the major causes of death in the India, therefore present study, was aimed to study the lipid profile, enzymatic antioxidant and oxidative stress in cardiovascular diseases. The study was carried out in the Department of Biochemistry and Medicine MGM Medical College and Hospital, Mumbai. 5ml. Blood sample was drawn into plain vacutainers and was utilised for estimation of lipid profile, oxidative stress markers concentration and antioxidant enzymes activities. The mean values of Total cholesterol, LDL TG, and MDA were significantly increased in CVD patients as compared to control (p<0.0001) and HDL, NO, SOD, CAT in CVD patients were significantly decreased as compared to control (p<0.0001). The present study reveals the importance of determining the lipid profile, free radicals and antioxidant status in CVD to enable the formulation of specific therapies for early intervention and better management of disease.


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