scholarly journals Carcinoma of the Rectum: A Clinicopathological Evaluation of Patients in Tertiary Care Hospitals

2020 ◽  
Vol 24 (1) ◽  
pp. 15-20
Author(s):  
Mohammad Arif Hossain ◽  
Md Jahangir Kabir Bhuiyan ◽  
Tutul Talukdar ◽  
Feroze Quader

Background: Colorectal carcinoma is the fourth most commonly diagnosed cancer and the third leading cause of cancer deaths worldwide. The rectum is the most frequent site involved. The disease is no less common in our country in comparison to western world. The aim of this study was to determine the incidence and to review the clinicopathological aspects of carcinoma rectum in different ages in our country. Methods: This is a prospective observational study which includes 50 cases of carcinoma rectum which were admitted under different surgical units of Dhaka Medical College Hospital and Bangabandhu Sheikh Mujib Medical University during the period of November 2007 to December 2008. Results: The present study showed maximum incidence of carcinoma rectum in the age group 21-30 years. Next common age group was 31-40 years. Incidence declined after 60 years. Majority of victims were male giving a male to female ratio of 1.17:1. As regards the mode of clinical presentation, most patients presented with bleeding per rectum. Majority of patients in this study was moderately anaemic. Curative resection was possible in 54% cases, palliative resection in 38% and palliative end colostomy was done in 4% cases. Only 2% mortality was reported in this study. Histopathological grading showed that poorly differentiated adenocarcinoma of rectum was more common in younger age group. Conclusion: Younger patients with carcinoma rectum have several distinct clinicopathological features. Since early diagnosis is essential to improve the cure rate for carcinoma rectum, all known procedure tools must be used to detect carcinoma of the rectum in an early stage, in addition to periodic selective investigations of high-risk group. Journal of Surgical Sciences (2020) Vol. 24 (1) : 15-20

2017 ◽  
Vol 28 (1) ◽  
pp. 9-11
Author(s):  
Naireen Sultana ◽  
Nahid Sultana ◽  
Rabeya Sultana ◽  
Rowshan Ara Begum

Bangladesh is a developing country where maternal death due to obstetric haemorrhage is very high. This study was carried out at Dhaka medical college hospital from January 2013 to December 2013. The aim of this study was to identify the different life threatening complications due to obstetric haemorrhage and also to identify the major causes of maternal death due to obstetric haemorrhage. From total 8500 obstetric admissions during 2013, 597 cases were of obstetric haemorrhage, giving the incidence of 7.02%. PPH was the most common cause of maternal death (75%). Those who survived among them (49.50%) women had PPH. The women who experienced several severe morbidities were in the age group between 20-24year (61.38%). Those who died their age group was 25-29 years (39.28%). Both in morbid cases and death cases most of the women belonged to lower middle class (62.37% and 60.71%). In both groups those who had life threatening complications and those who died most of them came from sub urban area (52.47% and 53.57%). About 42.85% in morbid cases had no regular antenatal check up and those who died among them 42.85% patient also did not take any antenatal checkup . 67.85 % of the death cases had circulatory failure and 59.40% of the severely morbid women also had circulating failure . Next to circulatory failure other morbidities were pulmonary edema ( 29.70%), septicemia ( 4.95%) & DIC (1.98%). Hence the result of the study clearly indicated that low socioeconomic states, irregular antenatal cheek up influence the outcome of obstetric hemorrhage. All death from obstetric hemorrhage are not preventable but regular antenatal check up by well trained health personals can recognize the high risk group or any complications at an early stage and appropriate measures can be taken.Medicine Today 2016 Vol.28(1): 9-11


2021 ◽  
pp. 60-61
Author(s):  
Shibani Pal ◽  
Shabarna Roy ◽  
Surajit Sasmal ◽  
Saikat Bhattacharya ◽  
Malay. K. Dasgupta

Introduction: Accidental kerosene poisoning in pediatric age group is still a common problem in India. It causes considerable morbidity and occasional mortality. The objective of our study is to determine the pattern and severity of kerosene poisoning cases presenting to our emergency department and to discuss the various risk factors heralding adverse outcome. Methodology: Data were collected over a period of three years from 1..3.2017-29.2.2020.Atotal 75 children were studied. A detailed history was taken using the proforma having special reference to age, sex, seasonal inuence and thorough clinical examination was carried out including anthropometry, general and systemic details and data were compiled and subjected to statistical analysis with the help of spss software. Results: Among 75 children with acute kerosene poisoning majority were I the toddler age group accounting to 93.33%. Males outnumbered the females with male female ratio 1.52:1.Seasonal preponderance were noted in the month of March to June followed by second peaking in the month of October and November. The casualties mostly took place in the own domestic premises. Potentially harmful habits of keeping kerosene in water storing bottles within the reach of the children were practiced by most of the householders.The most common clinical presentations were fever(93%), cough(90%) and vomiting (85%).Pneumonitis occurred in 31 patients and CNS involvement could be documented in three only. Mean Hospital stay were of three days. All patients improved except two died. Severe Protein energy Malnutrition, presence of complications and prolonged hospital staywere associated with adverse outcome. Extensive radiological ndngs in CXR 6 hours after the ingestion showed signicant coorelation with prolonged hospital stay


Author(s):  
Deepa Hatwal ◽  
Chitra Joshi ◽  
Ranjan Agrawal

Introduction: Ovarian sex cord-stromal tumours, including Granulosa Cell Tumours (GCTs), are a group of neoplasm that occurs rarely, especially in children. Only 0.1% of all ovarian tumours and 4-5% of GCTs occur in children. They commonly present as precocious puberty especially in prepubertal girls. Aim: To analyse the clinico-pathological features along with the laboratory findings of ovarian mass. Materials and Methods: A prospective study in tertiary care teaching institutions was carried out during a three year study period starting from April 2017 to March 2020. The study was carried out in tertiary care teaching institutions i.e., VCSGG Medical Sciences and Research Institute, Srinagar Garhwal, PauriGarhwal, Doon Medical College, Dehradun and Rohilkhand Medical College, Bareilly. A total of 11 cases of Juvenile Granulosa Cell Tumour (JGCT) among girls in the age group of 5-13 years who presented with precocious puberty were included in the present study. The results were analysed especially the clinico-laboratory parameters including histopathology and Immunohistochemistry (IHC) findings. All the patients underwent resection of the ovarian mass and were subjected to histopathological examination. Microscopy and IHC was compatible with the diagnosis of juvenile GCT in all the 11 cases. Results: Majority of the patients with GCTs of the ovary presented in the early stage. Of the 11 cases included, only one patient was aged 13 years; seven were in the age group of 5-8 years and three in the 9-12 years of age group. The laboratory profile in all showed an elevated Estradiol level, low Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) levels. Among the thyroid profile only the Triiodothyronine (T3) levels were raised while Thyroid Stimulating Hormone (TSH) and Thyroxine (T4) levels were within normal limits. All cases were histopathologically proved and confirmed using IHC markers. Surgery is the primary treatment modality for GCTs. Conclusion: Histopathology along with specific IHC is important in the diagnosis of JGCT. A careful search provides good insight of the tumour and its final outcome. Diagnosing JGCT especially in the early stage is important as they carry a favourable prognosis when treated in the initial phase.


2015 ◽  
Vol 24 (Number 1) ◽  
pp. 3-7
Author(s):  
A H M Karnal ◽  
K H Mollah ◽  
A Begum ◽  
K Khoda ◽  
S Tanzeem ◽  
...  

Dengue is a rapidly spreading mosquito-borne viral disease worldwide. The endemicity in Bangladesh is also increasing gradually. The study was a prospective observational one, documented the presenting features and outcome of management. It was carried out in Department of Medicine in Holy Family Red Crescent Medical College Hospital, Dhaka from June 2013 to December 2013. Total 100 admitted cases of both sera positive and sera-negative were included in this study. Detailed history was taken, clinical examination and relevant investigations were done. Out of 100 patients 54 (54%) were male and 46 (46%) were female. So male to female ratio was 1.7:1. The age of the patients ranged from 12-75 years. Among them 20-40 years age group was highest 63%. Patients of higher socio-economic group were (69%) more affected. Out of 100 cases 54 had classical dengue fever (DF), 46 had dengue hemorrhagic fever (DHF). Antibody was positive in 81% cases. All patients presented with high fever, headache in 90%, retro-orbital pain in 45%, body ache in 56%, and backache in 48%. Leucopenia found in 60, platelet count <100x1091L was in 57, HCT- normal 17, <20% rise in 48%, ?20% rise in 28%. With proper management all patients were recovered.


2020 ◽  
pp. 3-5
Author(s):  
Ayesha Goel ◽  
Ritu Nigam

Myiasis in head and neck region is a rare occurrence and is usually found in tropical countries like India. Poor hygiene, unsanitary living conditions, mental retardation, neglected wounds, diabetes mellitus and old age along with a warm and humid climate lay down a conducive environment for the larva of dipterous fly to infest humans. Maggots due to their tissue destructive properties can affect many regions in otolaryngorhinology like nasal cavity, ears, oral cavity, tracheostomy site ostoma, PNS, the skin and ulcerative lesions of head and neck. The burden of the disease lies in the fact that the complications range from minor tissue destruction, perforation of either the tympanic membrane, palate or septum, vertigo, angioedema to severe neurological manifestations, intracranial extension or rarely even death. Objective: To assess the commonly affected age group and gender infested by myiasis, it’s seasonal trend, socioeconomic status of the affected patients and the relationship of myiasis infestation with various predisposing factors. Methodology: Retrograde study was conducted on 95 patients of department of otorhinolaryngology. The study was done from January 2015 to October 2018 by collecting data of 3 years 10 months time interval and results tabulated. Ethical clearance was sort and patients consent obtained. Result: The most commonly affected age group was found to be elderly, in the 7th decade of life (56.84%). Females were more commonly affected than males consisting of 55 out of 95 cases (57.89%), with a male female ratio of 1:1.4. Majority of cases presented in the months of October-January, with a peak in November (32/95). Nasal myiasis was found to be more common (69 cases) in comparison to aural and oral cavity myiasis. The most common predisposing factor was found to be Atrophic Rhinitis in 66.7% cases. Conclusion : With awareness and improved personal hygiene a devastating disease like myiasis is easily preventable and curable.


2014 ◽  
Vol 15 (2) ◽  
pp. 118-121
Author(s):  
Aparna Das ◽  
Modhusudan Saha ◽  
Bimal Chandra Shil ◽  
Rubina Yasmin ◽  
Gobinda Banik ◽  
...  

Background: The pattern and incidence of Carcinoma Stomach vary widely in different parts of the world. Overall it is the 2nd most common cause of death but in some Asian countries, it is still the commonest cause of cancer death in patients of > 50 years.Aim: To analyze the clinical presentation and histological findings of patients of carcinoma of the stomach. Methods and materials: This study was done over a period of 2 years between January 2011 and December 2012. Adult patients (Age more than 18 years) of histologically confirmed as having carcinoma stomach were included in the study. Studied variables included age, gender, socioeconomic status, clinical presentations, site of lesion, histopathological subtypes. Diagnostic modalities included abdominal ultrasound, upper GI (gastrointestinal) endoscopy and endoscopic biopsy to confirm the diagnosis. Results: Total number of patients included in this study was 150. The number of patients in <50 years age group and >50 years age group were 50 (33.33%) & 100 (66.66%) respectively. The median age at presentation was 57 years. The peak incidence was in 61-70 years age group. In our study,male: female ratio being 2.3:1. By occupation, farmer 74 (49%), housewife 37(24.6%), serviceholder12(8%), business man 5(10%) and others12 (8%). 71 (47.4%) patients were from lower socioeconomic group, middle74 (49.4%), upper class 5 (3.4%) & only 63 (42%) were literate. The common clinical features were vomiting 28%, abdominal pain 18%, weight loss and anorexia 17.3% , dyspepsia 16% , Anaemia (26% ), Abdominal mass 4%, Metastatic lymph node 4%, Ascites 1.3%. lesions are involved in Cardia 14%, Body &Antrum 6.6%, Antrum 2.6%, Body 23.3%, Fundus 2% and Diffusely in 1.3% cases. Conclusion: As regards to clinical presentation, patients in our country are presenting more with features of gastric outlet obstruction whereas abdominal lump and upper GI bleeding are more common in Western world. If gastric carcinoma is diagnosed at an early stage, patients can have a highly favorable prognosis.DOI: http://dx.doi.org/10.3329/jom.v15i2.20683 J MEDICINE 2014; 15 : 118-121


2014 ◽  
Vol 38 (1) ◽  
pp. 5-10
Author(s):  
Nasir Uddin Mahamud ◽  
Sanat Kumar Barua ◽  
Pranab Kumar Chowdhury ◽  
Md Rezaul Karim ◽  
Prabad Chandra Barua ◽  
...  

Introduction: Acute encephalitis is potentially harmful central nervous system (CNS) inflammation usually caused by infections. The diagnosis is difficult to establish and the etiology often remain unclear. It is endemic throughout the year with occasional epidemics in various localities in our country. So this study was carried out to see the clinical and epidemiological background of hospitalized children with encephalitis. Methodology: A retrospective, observational study, conducted in the department of Paediatrics, Chittagong Medical College Hospital (CMCH). The study period was from January 2009 to December 2010. Children with all ages and sex with clinical case definition of encephalitis characterized by new onset of fever (tempareturee”380C) or history of fever during present illness along with altered mental status (confusion, disorientation, coma) and/or neurological deficit (focal or diffuse neurological dysfunction or new onset of seizure) were included. Results: A total of 666 cases were analyzed during the study period. The mean age of the children was 3.77 years (SD± 2.9 years), most of the cases (48.5%) were between 12 months to 60 months age group. Urban cases were 144 (25%) & rural cases were 421 (75%).Year wise admissions in 2009 & 2010 were 312 & 354; deaths were 46% & 56%. Prominent clinical features of admitted encephalitis patients were fever (89%), convulsion (84%) and altered consciousness (75%). The trend of admission was high in the months of January, April and October. Significant number of death were observed under 5 year’s age group (P value <0.02%). Conclusion: It was observed from this study that clinical profiles among children with encephalitis can help to understand the course and epidemiological pattern of the disease. The spectrum of encephalitis can differ from rural to urban area and the months of January, April and October were the peak seasons for encephalitis in south-east region of Bangladesh; probably due to viral surge. DOI: http://dx.doi.org/10.3329/bjch.v38i1.20020 Bangladesh J Child Health 2014; VOL 38 (1) : 5-10


2021 ◽  
Vol 7 (1) ◽  
pp. 56-59
Author(s):  
Sumiya Bent Kalam ◽  
Sadia Islam ◽  
Mohammad Abdullah Az Zubayer Khan ◽  
Tanjina Akhter

Background: Elderly people are posing a significant health burden in our country for their multi morbidity as economic growth has increased our life expectancy. Pattern of multi morbidity of this older people varies according to geography, ethnicity, culture and life style. Aim: The aim of this study was to identify the prevalence and pattern of multi morbidity of elderly patients admitted in a tertiary care hospital. Method: 50 random cases of elderly patients aged more than 60 years admitted in medicine and allied wards of Dhaka medical college hospital were observed at this cross-sectional study from January 2017 to June 2017(total 6 months period). Data were reviewed and analyzed using simple frequency and percentage. Protocol was reviewed by institutional ethical board (IRB) of Dhaka medical college hospital. Result: A total number of 50 elderly patients with age ranging from 60 to 95 years were observed with male and female ratio 1.3:1 having multi morbidity among 92.0% patients and female is more affected than male. Hypertension, ischemic heart disease, diabetes mellitus and stroke were found most common diseases as individual. Hypertension and diabetes mellitus was found as the most common multi morbidity pattern followed by hypertension and IHD, stroke & diabetes mellitus. Conclusion: This study sheds light on priority needs of elderly patients in terms of medical facility in tertiary care hospital of Bangladesh. Journal of National Institute of Neurosciences Bangladesh, January 2021, Vol. 7, No. 1, pp. 56-59


2019 ◽  
Vol 32 (1) ◽  
pp. 62-69 ◽  
Author(s):  
Tamanna Tasnim ◽  
Md Mizanur Rahman ◽  
Ariful Alam ◽  
Rupsha Nura Laila ◽  
Abdul Matin ◽  
...  

Intestinal Obstruction is a common surgical emergency and constitutes a major cause of morbidity and financial expenditure in hospitals around the world. This study aimed to provide the current spectrum of intestinal obstruction in a tertiary care hospital with a special view to identify any change in the aetiologic pattern. This prospective observational study was carried out in all four surgical units of Rajshahi Medical College Hospital from September 2010 to August 2011. The study included 250 adult patients with clinical and radiological evidence of complete intestinal obstruction. Out of 250 consecutive patients ranging between (13-90) years with a male to female ratio of 2.1:1, the maximum cases were within (31-40) years and (51-60) years of age group. In this study 175 cases (70%) were presented with small bowel and 75 cases (30%) with large bowel obstruction. The main causes of obstructions were bands and adhesions (44%) followed by volvulus (18%), external hernias (16%), neoplasm (12%), intussusceptions (3.2%), intestinal tuberculosis (2.8%) and miscellaneous (4%). Approximately, 86% patient with adhesive obstructions had previous laparotomy while 42% needed surgical exploration for failed conservative management. The overall mortality was 8%; mainly owing to strangulating obstruction and old age. Varying degrees of wound infections were the common post-operative complications. There was a significant change in the aetiologic pattern of intestinal obstruction. Post operative adhesions were the commonest cause of obstruction and appendicectomy was the most common previous operation causing adhesion. TAJ 2019; 32(1): 62-69


2017 ◽  
Vol 3 (1) ◽  
pp. 3-5 ◽  
Author(s):  
Md Shafiul Alam ◽  
Md Abdus Salam ◽  
Tayseer Farzana ◽  
ASM Raushan Newaz ◽  
Md Saiful Islam

Background: Spinal tuberculosis is more frequently reported in developing countries.Objective: The purpose of the present study was to see the socio-demographic characteristics of spinal tuberculosis patients.Methodology: This study was carried out in the Department of Neurosurgery, Dhaka Medical College Hospital during the period of January 2002 to December 2004 to elucidate the effectiveness of surgical and conservative treatment of the tuberculosis of the spine. For this purpose, a total number of 50 consecutive cases admitted during the study period with tuberculosis of the spine supported by investigations were included in this study.Result: The mean age of the patients was 25.4 years and ranged from 7 years to 68 years. The highest incidence of tuberculosis of the spine was found in age group between 11 to 20 years and 70% of the patients were under 30 years of age. Incidence of tuberculosis of this spine was more in male (62%) in comparison to female (3 8%) with a male female ratio of 1.63:1. In this study most of the patients came from low class society (66%) followed by middle class (28%) and high class (6%) respectively.Conclusion: Spinal TB more frequently occurs among the young age group with a male predominance.Bangladesh Journal of Infectious Diseases 2016;3(1):3-5


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